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The map label for this gene is mogA [H]

Identifier: 157368934

GI number: 157368934

Start: 759499

End: 760086

Strand: Direct

Name: mogA [H]

Synonym: Spro_0689

Alternate gene names: 157368934

Gene position: 759499-760086 (Clockwise)

Preceding gene: 157368933

Following gene: 157368935

Centisome position: 13.94

GC content: 58.16

Gene sequence:

>588_bases
ATGGACATATTACGTATTGGTTTGGTTTCCGTTTCTGACCGCGCTTCCGGCGGCGTTTACCAGGATAAAGGGATACCGGC
GCTGGAGGAATGGCTGACTGGCGCGCTGAGCACTCCGTTTAAGCTGGAGACCCGCCTGATCCCTGATGAGCAGACGTTGA
TCGAACAAACCCTGTGTGAGCTGGTGGATGAAATGGGCTGCCATCTGGTGCTGACCACCGGTGGTACCGGCCCCGCGCGC
CGCGACGTGACGCCTGACGCCACCTTGGCCATTGCCGATCGCGTGATGCCCGGCTTCGGCGAGCAAATGCGTCAAATCAG
CCTACACTATGTGCCAACGGCCATTCTTTCACGTCAGGTGGGGGCAATCCGCAAGCAGGCATTGATCATCAACCTGCCGG
GGCAACCCAAGTCGATCAAGGAAACGCTGGAAGGGGTTAAGGACGAGCAGGGCAAGGTGGTGGTGCATGGCATCTTCGCC
AGCGTGCCGTACTGCATACAGTTGCTTGAGGGGCCCTATGTGGAAACCGAGGCGGCAGTGGTAGCAGCATTTCGTCCGAA
GAATGCGCGTCGCGAGATAAACATCTAA

Upstream 100 bases:

>100_bases
CTGCAGATCCCGCAGGCAGGCAGACACTTTATACTCTCAAGATTGAAAATAGGGCGGGGAGCGAACCCGTCCGAACCCCA
TCAGGCTGTAGAGGTTACGC

Downstream 100 bases:

>100_bases
ATTTCAGCCTTTTGTGAGATTAGCGCTAGCCGATCTGGTGTGAAAATAATTTGCCGTTATAGTAAGGATTCGTTTACAGA
AAGCCGCTGGCTTTTATTTT

Product: molybdenum cofactor biosynthesis protein MogA

Products: NA

Alternate protein names: MPT adenylyltransferase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MDILRIGLVSVSDRASGGVYQDKGIPALEEWLTGALSTPFKLETRLIPDEQTLIEQTLCELVDEMGCHLVLTTGGTGPAR
RDVTPDATLAIADRVMPGFGEQMRQISLHYVPTAILSRQVGAIRKQALIINLPGQPKSIKETLEGVKDEQGKVVVHGIFA
SVPYCIQLLEGPYVETEAAVVAAFRPKNARREINI

Sequences:

>Translated_195_residues
MDILRIGLVSVSDRASGGVYQDKGIPALEEWLTGALSTPFKLETRLIPDEQTLIEQTLCELVDEMGCHLVLTTGGTGPAR
RDVTPDATLAIADRVMPGFGEQMRQISLHYVPTAILSRQVGAIRKQALIINLPGQPKSIKETLEGVKDEQGKVVVHGIFA
SVPYCIQLLEGPYVETEAAVVAAFRPKNARREINI
>Mature_195_residues
MDILRIGLVSVSDRASGGVYQDKGIPALEEWLTGALSTPFKLETRLIPDEQTLIEQTLCELVDEMGCHLVLTTGGTGPAR
RDVTPDATLAIADRVMPGFGEQMRQISLHYVPTAILSRQVGAIRKQALIINLPGQPKSIKETLEGVKDEQGKVVVHGIFA
SVPYCIQLLEGPYVETEAAVVAAFRPKNARREINI

Specific function: Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Homo sapiens, GI10880983, Length=179, Percent_Identity=34.6368715083799, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI66932975, Length=179, Percent_Identity=34.6368715083799, Blast_Score=92, Evalue=4e-19,
Organism=Escherichia coli, GI1786190, Length=194, Percent_Identity=87.1134020618557, Blast_Score=355, Evalue=1e-99,
Organism=Caenorhabditis elegans, GI17564954, Length=149, Percent_Identity=36.9127516778523, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17136978, Length=146, Percent_Identity=32.1917808219178, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24638841, Length=146, Percent_Identity=32.1917808219178, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 21230; Mature: 21230

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILRIGLVSVSDRASGGVYQDKGIPALEEWLTGALSTPFKLETRLIPDEQTLIEQTLCE
CCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
LVDEMGCHLVLTTGGTGPARRDVTPDATLAIADRVMPGFGEQMRQISLHYVPTAILSRQV
HHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GAIRKQALIINLPGQPKSIKETLEGVKDEQGKVVVHGIFASVPYCIQLLEGPYVETEAAV
HHHHHCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCEE
VAAFRPKNARREINI
EEEECCCCCCCCCCC
>Mature Secondary Structure
MDILRIGLVSVSDRASGGVYQDKGIPALEEWLTGALSTPFKLETRLIPDEQTLIEQTLCE
CCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHH
LVDEMGCHLVLTTGGTGPARRDVTPDATLAIADRVMPGFGEQMRQISLHYVPTAILSRQV
HHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
GAIRKQALIINLPGQPKSIKETLEGVKDEQGKVVVHGIFASVPYCIQLLEGPYVETEAAV
HHHHHCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCEE
VAAFRPKNARREINI
EEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]