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The map label for this gene is deoC

Identifier: 157368905

GI number: 157368905

Start: 725574

End: 726353

Strand: Direct

Name: deoC

Synonym: Spro_0660

Alternate gene names: 157368905

Gene position: 725574-726353 (Clockwise)

Preceding gene: 157368904

Following gene: 157368906

Centisome position: 13.32

GC content: 59.87

Gene sequence:

>780_bases
ATGACCGAATTAACCGCAGCAGCGCAACGTGCGCTGACCTTAATGGATTTGACCACGCTGAACGATGATGACACCGATGA
GAAAGTGATCGCGCTGTGTCGTCAGGCGAACAGCCCGGCCGGGCATACCGCGGCCATCTGCATTTACCCGCGCTTTATTC
CGGCGGCACGCAAGGCCCTGCGTGAGCAGGGGACGCCAGACATCCGCATTGCGACCGTCACCAACTTCCCGCATGGCAAC
GATGATATCGAGATCGCGCTGGCGGAAACCCGTGCGGCTATCGCTTACGGTGCCGATGAAGTGGACGTGGTGTTCCCATA
CCGCGCACTGATCGCCGGTAATGAGCAGGTCGGTTTTGAGCTGGTGAAACAGTGCAAGCAGGCCTGTTTGGCCGCCAACG
TGCTGCTGAAAGTGATCATCGAAACCGGTGAGCTCAAGCAGGCCAATCTGATCCGCAAGGCTTCGGAAATTGCCATCAAT
GCCGGCGCGGACTTTATCAAGACCTCAACCGGTAAAGTGCCTGTCAACGCGACGCTGGAAAGCGCCGAGCTGATGATGTC
GGTGATCCGCGATATGGGCGTCGCCAAGACGGTGGGCTTCAAGCCGGCCGGCGGTGTGCGTACGGCGGAAGATGCACTGC
ATTACCTGCAACTTGCCGATCGTATTCTGGGTGAAGGCTGGGCCGATGCGCGCCATTTCCGCTTCGGGGCTTCCAGCCTG
TTAGCCAGCCTGTTGGCGACGCTGGGCCACGGTGCCGAGCCGTCTGGCAGCGGTTACTGA

Upstream 100 bases:

>100_bases
GAGAAGGATCTCAGTTGCCGATGAGGGACCCGTTCCCCAGCGCTATCTTCAAGGAACCAAGTCCGCTCGCCAACACCCAG
GTTCTCAGTTGGAGAGTTTT

Downstream 100 bases:

>100_bases
TCGATTCCGTCGGCAAGGCGCGATATGGCGTCTGCCTGCACTCTACATTAGCTAAAACAGGGGGATGCCTTGTTCCTGGC
ACAAGAAATTATTCGTAAAA

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MTELTAAAQRALTLMDLTTLNDDDTDEKVIALCRQANSPAGHTAAICIYPRFIPAARKALREQGTPDIRIATVTNFPHGN
DDIEIALAETRAAIAYGADEVDVVFPYRALIAGNEQVGFELVKQCKQACLAANVLLKVIIETGELKQANLIRKASEIAIN
AGADFIKTSTGKVPVNATLESAELMMSVIRDMGVAKTVGFKPAGGVRTAEDALHYLQLADRILGEGWADARHFRFGASSL
LASLLATLGHGAEPSGSGY

Sequences:

>Translated_259_residues
MTELTAAAQRALTLMDLTTLNDDDTDEKVIALCRQANSPAGHTAAICIYPRFIPAARKALREQGTPDIRIATVTNFPHGN
DDIEIALAETRAAIAYGADEVDVVFPYRALIAGNEQVGFELVKQCKQACLAANVLLKVIIETGELKQANLIRKASEIAIN
AGADFIKTSTGKVPVNATLESAELMMSVIRDMGVAKTVGFKPAGGVRTAEDALHYLQLADRILGEGWADARHFRFGASSL
LASLLATLGHGAEPSGSGY
>Mature_258_residues
TELTAAAQRALTLMDLTTLNDDDTDEKVIALCRQANSPAGHTAAICIYPRFIPAARKALREQGTPDIRIATVTNFPHGND
DIEIALAETRAAIAYGADEVDVVFPYRALIAGNEQVGFELVKQCKQACLAANVLLKVIIETGELKQANLIRKASEIAINA
GADFIKTSTGKVPVNATLESAELMMSVIRDMGVAKTVGFKPAGGVRTAEDALHYLQLADRILGEGWADARHFRFGASSLL
ASLLATLGHGAEPSGSGY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 2 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=258, Percent_Identity=39.5348837209302, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI1790841, Length=259, Percent_Identity=81.0810810810811, Blast_Score=391, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17533015, Length=247, Percent_Identity=39.2712550607287, Blast_Score=164, Evalue=4e-41,
Organism=Drosophila melanogaster, GI19922098, Length=268, Percent_Identity=37.3134328358209, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_SERP5 (A8G9H6)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476894.1
- ProteinModelPortal:   A8G9H6
- SMR:   A8G9H6
- STRING:   A8G9H6
- GeneID:   5605713
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0660
- eggNOG:   COG0274
- HOGENOM:   HBG636421
- OMA:   CKEACGD
- ProtClustDB:   PRK05283
- BioCyc:   SPRO399741:SPRO_0660-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00592
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 27550; Mature: 27419

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: ACT_SITE 167-167 ACT_SITE 201-201

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELTAAAQRALTLMDLTTLNDDDTDEKVIALCRQANSPAGHTAAICIYPRFIPAARKAL
CCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHH
REQGTPDIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVDVVFPYRALIAGNEQVGFE
HHCCCCCEEEEEEECCCCCCCCEEEEEECHHHHHHCCCCCEEEEECHHHHHCCCHHHHHH
LVKQCKQACLAANVLLKVIIETGELKQANLIRKASEIAINAGADFIKTSTGKVPVNATLE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCHHCCCCCCCCCCCCHH
SAELMMSVIRDMGVAKTVGFKPAGGVRTAEDALHYLQLADRILGEGWADARHFRFGASSL
HHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHH
LASLLATLGHGAEPSGSGY
HHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TELTAAAQRALTLMDLTTLNDDDTDEKVIALCRQANSPAGHTAAICIYPRFIPAARKAL
CCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCCCCCEEEEEEECHHHHHHHHHH
REQGTPDIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVDVVFPYRALIAGNEQVGFE
HHCCCCCEEEEEEECCCCCCCCEEEEEECHHHHHHCCCCCEEEEECHHHHHCCCHHHHHH
LVKQCKQACLAANVLLKVIIETGELKQANLIRKASEIAINAGADFIKTSTGKVPVNATLE
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEECCCCHHCCCCCCCCCCCCHH
SAELMMSVIRDMGVAKTVGFKPAGGVRTAEDALHYLQLADRILGEGWADARHFRFGASSL
HHHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHH
LASLLATLGHGAEPSGSGY
HHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA