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The map label for this gene is dgoA [C]

Identifier: 157368885

GI number: 157368885

Start: 705606

End: 706883

Strand: Direct

Name: dgoA [C]

Synonym: Spro_0640

Alternate gene names: 157368885

Gene position: 705606-706883 (Clockwise)

Preceding gene: 157368884

Following gene: 157368886

Centisome position: 12.95

GC content: 61.03

Gene sequence:

>1278_bases
ATGACCACAATTACCGCACTGCGGGTTGAAGATATTCGCTTCCCCACCTCGCTGGCGCTGGACGGATCCGATGCGATGAA
TCCGGATCCGGACTATTCCGCCGCCTACGTGATCCTGGAGACCGATCGTGACGATCTGACCGGCCACGGGCTGACCTTTA
CCATCGGCCGCGGCAATGAGATCTGCTGTGCGGCGATCCGCGCGCTGGAGCATCAGATCGTCGGGGTTTCGTTGGAAGAG
ATCGCCGCCGATATGGGCGCCTTCTGGCGACGTTTTACCGGTGACAGCCAGTTGCGCTGGATCGGCCCGGACAAGGGCGC
GATCCACCTGGCGACCGGGGCGGTGATCAACGCGGTTTGGGATCTGTGGGCCAAGGCCGAGGGTAAACCGGTGTGGCGAC
TGGTGGCAGAGATGACGCCAGAGGAGCTGGTACGCTGCATCGATTTTCGCTACATCACTGACTGCATTACGCCGCAGGAA
GCGCTTACCTTGCTCAGGCAGCGGGCGCACGGCAAGGAGCAGCGCCTGGAGCGGCTGCTGCAGGACGGGTATCCCTGCTA
CACCACCTCCGCCGGTTGGTTGGGTTACCCGGACGATAAGCTGCGCCGGTTGTGCCAGGAAGCGGTCGACGCCGGTTTCT
CCTACCTGAAGCTGAAGGTCGGGCGCGATCTGGAAGATGATATTCGCCGGGTGCGCATTGCCCGCGAGGTGATCGGCCCC
GATCGTCAACTGATGATCGACGCCAACCAGGTTTGGGAAGTCAACGACGCCATTCCCTGGGTGAAGCATCTGGCGTTCGC
CAAACCCTGGTTTATCGAAGAACCGACCAGCCCGGACGACGTGGAAGGGCACCGCCGTATCCGCGAAGGGGTGCATCCGG
TCAAGGTGGCCACCGGCGAGATGTGCCAAAACCGCATCCTGTTCAAGCAGTTCATCATGCGCGAAGCGATTGACGTGGTG
CAGATCGACGCCTGTCGCCTGGGGGGCGTTAATGAAGTGCTGGCGGTGATGCTAATGGCGGCCAAATACAACCTGCCGGT
GTGCCCGCATGCCGGTGGCGTGGGACTGTGCGAATACGTTCAACATCTGTCGATGATCGACTACCTGTGCATTGCCGGCA
CCCACGACGGCCGGGTGATCGAATACGTCGATCATCTGCATGAACATTTTGTCCATCCCTGTGAGGTCAAGGGGGCGGCC
TATATGCCACCGCTCAATCCCGGATATTCGATCGAGATGCATGCGGCGTCGCTCGAACAGTACCGGTTCCGCGGTTGA

Upstream 100 bases:

>100_bases
ACGCCGGTCTACCTGAAGGCCGGGCAGACGATGCGCCTGGGCATTGAAGGATTGGGTGAACAGTGTCAAACAACCGTACA
AGCCTGATGGGGAGCATGCC

Downstream 100 bases:

>100_bases
ACGGGAAACTAACCATGCTGCGCATCGATGCTCACCAACATTACTGGCATTACCAGCCGCAACGCTATCCGTGGATCAGC
GAGCAGATGGCGGTGTTGCA

Product: mandelate racemase/muconate lactonizing protein

Products: Glyceraldehyde 3-phosphate; Pyruvate [C]

Alternate protein names: Mandelate Racemase/Muconate Lactonizing; Mandelate Racemase; Racemase; Mandelate Racemase/Muconate Lactonizing-Like Protein; Mandelate Racemase/Muconate Lactonizing Family Protein; Uroporphyrinogen Decarboxylase HemE; Galactonate Dehydratase; Mandelate Racemase/Muconate Lactonizing Domain Protein; Mandelate Racemase Protein; Mandelate Racemase/Muconate Lactonizing Family Protein; Mandelate Racemase/Muconate Lactonizing -Like Protein; Dehydratase; L-Alanine-DL-Glutamate Epimerase; L-Fuconate Dehydratase; Dehydratase Member Of Enolase Family; Phosphopyruvate Hydratase; Mandalate Racemase; Mandelate Racemase/Muconate Lactonizing Protein; RTS Beta Protein; Mandelate Racemase / L-Alanine-DL-Glutamate Epimerase; Chloromuconate Cycloisomerase Protein; Muconate Cycloisomerase

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTTITALRVEDIRFPTSLALDGSDAMNPDPDYSAAYVILETDRDDLTGHGLTFTIGRGNEICCAAIRALEHQIVGVSLEE
IAADMGAFWRRFTGDSQLRWIGPDKGAIHLATGAVINAVWDLWAKAEGKPVWRLVAEMTPEELVRCIDFRYITDCITPQE
ALTLLRQRAHGKEQRLERLLQDGYPCYTTSAGWLGYPDDKLRRLCQEAVDAGFSYLKLKVGRDLEDDIRRVRIAREVIGP
DRQLMIDANQVWEVNDAIPWVKHLAFAKPWFIEEPTSPDDVEGHRRIREGVHPVKVATGEMCQNRILFKQFIMREAIDVV
QIDACRLGGVNEVLAVMLMAAKYNLPVCPHAGGVGLCEYVQHLSMIDYLCIAGTHDGRVIEYVDHLHEHFVHPCEVKGAA
YMPPLNPGYSIEMHAASLEQYRFRG

Sequences:

>Translated_425_residues
MTTITALRVEDIRFPTSLALDGSDAMNPDPDYSAAYVILETDRDDLTGHGLTFTIGRGNEICCAAIRALEHQIVGVSLEE
IAADMGAFWRRFTGDSQLRWIGPDKGAIHLATGAVINAVWDLWAKAEGKPVWRLVAEMTPEELVRCIDFRYITDCITPQE
ALTLLRQRAHGKEQRLERLLQDGYPCYTTSAGWLGYPDDKLRRLCQEAVDAGFSYLKLKVGRDLEDDIRRVRIAREVIGP
DRQLMIDANQVWEVNDAIPWVKHLAFAKPWFIEEPTSPDDVEGHRRIREGVHPVKVATGEMCQNRILFKQFIMREAIDVV
QIDACRLGGVNEVLAVMLMAAKYNLPVCPHAGGVGLCEYVQHLSMIDYLCIAGTHDGRVIEYVDHLHEHFVHPCEVKGAA
YMPPLNPGYSIEMHAASLEQYRFRG
>Mature_424_residues
TTITALRVEDIRFPTSLALDGSDAMNPDPDYSAAYVILETDRDDLTGHGLTFTIGRGNEICCAAIRALEHQIVGVSLEEI
AADMGAFWRRFTGDSQLRWIGPDKGAIHLATGAVINAVWDLWAKAEGKPVWRLVAEMTPEELVRCIDFRYITDCITPQEA
LTLLRQRAHGKEQRLERLLQDGYPCYTTSAGWLGYPDDKLRRLCQEAVDAGFSYLKLKVGRDLEDDIRRVRIAREVIGPD
RQLMIDANQVWEVNDAIPWVKHLAFAKPWFIEEPTSPDDVEGHRRIREGVHPVKVATGEMCQNRILFKQFIMREAIDVVQ
IDACRLGGVNEVLAVMLMAAKYNLPVCPHAGGVGLCEYVQHLSMIDYLCIAGTHDGRVIEYVDHLHEHFVHPCEVKGAAY
MPPLNPGYSIEMHAASLEQYRFRG

Specific function: D-galactonate degradation; first step. D-galactonate degradation; third step. [C]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI42544119, Length=423, Percent_Identity=54.1371158392435, Blast_Score=506, Evalue=1e-143,
Organism=Homo sapiens, GI42544117, Length=406, Percent_Identity=52.9556650246305, Blast_Score=475, Evalue=1e-134,
Organism=Homo sapiens, GI186972148, Length=349, Percent_Identity=52.1489971346705, Blast_Score=404, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.2.21; 4.2.1.6 [C]

Molecular weight: Translated: 47881; Mature: 47750

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTITALRVEDIRFPTSLALDGSDAMNPDPDYSAAYVILETDRDDLTGHGLTFTIGRGNE
CCCEEEEEEECCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCH
ICCAAIRALEHQIVGVSLEEIAADMGAFWRRFTGDSQLRWIGPDKGAIHLATGAVINAVW
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEHHHHHHHHH
DLWAKAEGKPVWRLVAEMTPEELVRCIDFRYITDCITPQEALTLLRQRAHGKEQRLERLL
HHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHH
QDGYPCYTTSAGWLGYPDDKLRRLCQEAVDAGFSYLKLKVGRDLEDDIRRVRIAREVIGP
HCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
DRQLMIDANQVWEVNDAIPWVKHLAFAKPWFIEEPTSPDDVEGHRRIREGVHPVKVATGE
CCEEEEECCCEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEHHHH
MCQNRILFKQFIMREAIDVVQIDACRLGGVNEVLAVMLMAAKYNLPVCPHAGGVGLCEYV
HHHHHHHHHHHHHHHHHHHEEECHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
QHLSMIDYLCIAGTHDGRVIEYVDHLHEHFVHPCEVKGAAYMPPLNPGYSIEMHAASLEQ
HHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEEEHHHHHH
YRFRG
HHCCC
>Mature Secondary Structure 
TTITALRVEDIRFPTSLALDGSDAMNPDPDYSAAYVILETDRDDLTGHGLTFTIGRGNE
CCEEEEEEECCCCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEEECCCCH
ICCAAIRALEHQIVGVSLEEIAADMGAFWRRFTGDSQLRWIGPDKGAIHLATGAVINAVW
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEHHHHHHHHH
DLWAKAEGKPVWRLVAEMTPEELVRCIDFRYITDCITPQEALTLLRQRAHGKEQRLERLL
HHHHCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHH
QDGYPCYTTSAGWLGYPDDKLRRLCQEAVDAGFSYLKLKVGRDLEDDIRRVRIAREVIGP
HCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
DRQLMIDANQVWEVNDAIPWVKHLAFAKPWFIEEPTSPDDVEGHRRIREGVHPVKVATGE
CCEEEEECCCEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEHHHH
MCQNRILFKQFIMREAIDVVQIDACRLGGVNEVLAVMLMAAKYNLPVCPHAGGVGLCEYV
HHHHHHHHHHHHHHHHHHHEEECHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
QHLSMIDYLCIAGTHDGRVIEYVDHLHEHFVHPCEVKGAAYMPPLNPGYSIEMHAASLEQ
HHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCEEEEEHHHHHH
YRFRG
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Dehydro-3-deoxy-D-galactonate 6-phosphate [C]

Specific reaction: 2-Dehydro-3-deoxy-D-galactonate 6-phosphate <==> Glyceraldehyde 3-phosphate + Pyruvate [C]

General reaction: elimination of H2O C-O bond; Cleavage [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA