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The map label for this gene is ycgM [C]

Identifier: 157368884

GI number: 157368884

Start: 704747

End: 705592

Strand: Direct

Name: ycgM [C]

Synonym: Spro_0639

Alternate gene names: 157368884

Gene position: 704747-705592 (Clockwise)

Preceding gene: 157368883

Following gene: 157368885

Centisome position: 12.93

GC content: 59.93

Gene sequence:

>846_bases
ATGAAACTTTTACGTTATGGCGCACCGGGGCAGGAACGTCCGGGGATATTGGACAATCAGGGTCAGATCCGTGACCTCTC
GCAGCACATCGCCGATCTGAGTGGTGAGGCATTGCTGCCCGCCGCGTTGGACCAACTGCGCGCGCTGGACATCAACCAAC
TGCCGAAGGTGGCTGGACAGCCGCGTTTGGGGCCGTGCGTGGGCCACATCGGCAAGTTTATCTGTATTGGTCTCAATTAC
GCTGACCATGCGGCGGAAACCGGCGCGGCGATCCCCTCTGAACCAGTGGTGTTCAACAAGTGGACCAGCGCGGTGGTCGG
GCCGAACGATCAGGTGCAGATCCCGCGTGACTCGCTCAAGACCGACTGGGAGGTGGAGCTGGGGGTGATCATTGGTCAGG
GTGGGCGCTATATCAGCGAGCAGGACGCGATGCAGCACGTTGCCGGCTACTGCGTGATCAACGACGTCTCGGAGCGTGAA
TTCCAAATCGAACGCGGCGGCACCTGGGACAAGGGCAAGGGGTGCGACACCTTTGGCCCCACCGGCCCCTGGCTGGTGAC
TGCCGATGAAATTGCCGATCCCCATAGCCTGAATCTGTGGCTGGAAGTGGACGGCAAACGCTATCAGGACGGCAATACCA
GCACCATGATCTTCCGCATTCCACAAATTATCAGTTACCTGAGCCGCTTTATGAGTCTGCAACCGGGCGATGTGATCTCC
ACCGGTACGCCGCCGGGCGTCGGCATGGGGCAAAAGCCAACGCCGGTCTACCTGAAGGCCGGGCAGACGATGCGCCTGGG
CATTGAAGGATTGGGTGAACAGTGTCAAACAACCGTACAAGCCTGA

Upstream 100 bases:

>100_bases
GCGTCCGACGCCAGTTCCTATACCACAGGTACGGTGCAGATTATCGACGGCGGCTGGAGTAACTGAGGCCCTGACCATCT
ACTTTCTTAGTGAGGATTGC

Downstream 100 bases:

>100_bases
TGGGGAGCATGCCATGACCACAATTACCGCACTGCGGGTTGAAGATATTCGCTTCCCCACCTCGCTGGCGCTGGACGGAT
CCGATGCGATGAATCCGGAT

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKLLRYGAPGQERPGILDNQGQIRDLSQHIADLSGEALLPAALDQLRALDINQLPKVAGQPRLGPCVGHIGKFICIGLNY
ADHAAETGAAIPSEPVVFNKWTSAVVGPNDQVQIPRDSLKTDWEVELGVIIGQGGRYISEQDAMQHVAGYCVINDVSERE
FQIERGGTWDKGKGCDTFGPTGPWLVTADEIADPHSLNLWLEVDGKRYQDGNTSTMIFRIPQIISYLSRFMSLQPGDVIS
TGTPPGVGMGQKPTPVYLKAGQTMRLGIEGLGEQCQTTVQA

Sequences:

>Translated_281_residues
MKLLRYGAPGQERPGILDNQGQIRDLSQHIADLSGEALLPAALDQLRALDINQLPKVAGQPRLGPCVGHIGKFICIGLNY
ADHAAETGAAIPSEPVVFNKWTSAVVGPNDQVQIPRDSLKTDWEVELGVIIGQGGRYISEQDAMQHVAGYCVINDVSERE
FQIERGGTWDKGKGCDTFGPTGPWLVTADEIADPHSLNLWLEVDGKRYQDGNTSTMIFRIPQIISYLSRFMSLQPGDVIS
TGTPPGVGMGQKPTPVYLKAGQTMRLGIEGLGEQCQTTVQA
>Mature_281_residues
MKLLRYGAPGQERPGILDNQGQIRDLSQHIADLSGEALLPAALDQLRALDINQLPKVAGQPRLGPCVGHIGKFICIGLNY
ADHAAETGAAIPSEPVVFNKWTSAVVGPNDQVQIPRDSLKTDWEVELGVIIGQGGRYISEQDAMQHVAGYCVINDVSERE
FQIERGGTWDKGKGCDTFGPTGPWLVTADEIADPHSLNLWLEVDGKRYQDGNTSTMIFRIPQIISYLSRFMSLQPGDVIS
TGTPPGVGMGQKPTPVYLKAGQTMRLGIEGLGEQCQTTVQA

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=244, Percent_Identity=47.1311475409836, Blast_Score=216, Evalue=1e-56,
Organism=Homo sapiens, GI40786394, Length=202, Percent_Identity=48.5148514851485, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI215422413, Length=210, Percent_Identity=39.0476190476191, Blast_Score=143, Evalue=1e-34,
Organism=Homo sapiens, GI66348062, Length=202, Percent_Identity=40.0990099009901, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI13654274, Length=202, Percent_Identity=40.0990099009901, Blast_Score=142, Evalue=3e-34,
Organism=Escherichia coli, GI1787428, Length=182, Percent_Identity=38.4615384615385, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17557057, Length=179, Percent_Identity=39.1061452513966, Blast_Score=133, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6324161, Length=213, Percent_Identity=30.0469483568075, Blast_Score=91, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28572127, Length=271, Percent_Identity=40.9594095940959, Blast_Score=183, Evalue=9e-47,
Organism=Drosophila melanogaster, GI28571789, Length=205, Percent_Identity=37.0731707317073, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24663695, Length=243, Percent_Identity=32.5102880658436, Blast_Score=137, Evalue=9e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30419; Mature: 30419

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLRYGAPGQERPGILDNQGQIRDLSQHIADLSGEALLPAALDQLRALDINQLPKVAGQ
CCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECHHHHHHHHHCCHHHHHHHCCC
PRLGPCVGHIGKFICIGLNYADHAAETGAAIPSEPVVFNKWTSAVVGPNDQVQIPRDSLK
CCCCHHHHHHHCEEEEECCCHHHHHHCCCCCCCCCEEEECCCCEEECCCCCEECCHHHCC
TDWEVELGVIIGQGGRYISEQDAMQHVAGYCVINDVSEREFQIERGGTWDKGKGCDTFGP
CCCEEEEEEEEECCCCCCCHHHHHHHHHCEEEEECCCCCEEEEECCCCCCCCCCCCCCCC
TGPWLVTADEIADPHSLNLWLEVDGKRYQDGNTSTMIFRIPQIISYLSRFMSLQPGDVIS
CCCEEEEHHHCCCCCCEEEEEEECCCEECCCCCEEEEEEHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGMGQKPTPVYLKAGQTMRLGIEGLGEQCQTTVQA
CCCCCCCCCCCCCCEEEEECCCEEEECHHHCCHHHHHHHCC
>Mature Secondary Structure
MKLLRYGAPGQERPGILDNQGQIRDLSQHIADLSGEALLPAALDQLRALDINQLPKVAGQ
CCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEECHHHHHHHHHCCHHHHHHHCCC
PRLGPCVGHIGKFICIGLNYADHAAETGAAIPSEPVVFNKWTSAVVGPNDQVQIPRDSLK
CCCCHHHHHHHCEEEEECCCHHHHHHCCCCCCCCCEEEECCCCEEECCCCCEECCHHHCC
TDWEVELGVIIGQGGRYISEQDAMQHVAGYCVINDVSEREFQIERGGTWDKGKGCDTFGP
CCCEEEEEEEEECCCCCCCHHHHHHHHHCEEEEECCCCCEEEEECCCCCCCCCCCCCCCC
TGPWLVTADEIADPHSLNLWLEVDGKRYQDGNTSTMIFRIPQIISYLSRFMSLQPGDVIS
CCCEEEEHHHCCCCCCEEEEEEECCCEECCCCCEEEEEEHHHHHHHHHHHHCCCCCCEEE
TGTPPGVGMGQKPTPVYLKAGQTMRLGIEGLGEQCQTTVQA
CCCCCCCCCCCCCCEEEEECCCEEEECHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA