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The map label for this gene is hpcD [H]

Identifier: 157368874

GI number: 157368874

Start: 694793

End: 695179

Strand: Direct

Name: hpcD [H]

Synonym: Spro_0629

Alternate gene names: 157368874

Gene position: 694793-695179 (Clockwise)

Preceding gene: 157368873

Following gene: 157368875

Centisome position: 12.75

GC content: 58.66

Gene sequence:

>387_bases
ATGCCCCATTTTTACGCTGAATGTACCGACAACATTCGCCACGAGGCGGATTTGCCCGCGCTGTTTGCCAGGGTCAATCA
GGCACTGGCGGACACCGGTATTTTCCCCCTGGCCGGGGTGCGCAGCCGCGCCATCTGGCTCGATACCTGGCAGATGGCCG
ACGGCCAGCGGGACTACGCTTTTGTGCATATGACGTTGAAGATCGGCCACGGGCGCAGTCTGGAAAGCCGTGAACAGGTC
GGGGCGATGCTGTTCAGCCTGATCACCGAGCACTTCGCCGCGCTGATGGCCAGCCGCTATCTGGCGCTGTCGTTCACCAT
GGAAGAGTTGGATCCGGTGCTGAACTACAAGCAAAACAATGTCCACGCGCTATTTCGTAAAGAGTAA

Upstream 100 bases:

>100_bases
TGACGGCAAGGTGGAGTTTGTTACCCCGCTGTTTGCCAGTTCCGGCACCGGGCAAGTCAACGCCATCTTCCCGCTGCCGG
CCGAAGCCTGAGGAGTCTCC

Downstream 100 bases:

>100_bases
GGGGCCGTCCATGTTGAATAAAGAGCTGGTGAGCCGTGCCGTGCAGCGTTTGCATCAGGCGGAGCAGAACCGCGAGCAGA
TCCGCGCGCTGTCGCTGGAT

Product: 5-carboxymethyl-2-hydroxymuconate isomerase

Products: NA

Alternate protein names: 5-carboxymethyl-2-hydroxymuconic acid isomerase; CHM isomerase; CHMI [H]

Number of amino acids: Translated: 128; Mature: 127

Protein sequence:

>128_residues
MPHFYAECTDNIRHEADLPALFARVNQALADTGIFPLAGVRSRAIWLDTWQMADGQRDYAFVHMTLKIGHGRSLESREQV
GAMLFSLITEHFAALMASRYLALSFTMEELDPVLNYKQNNVHALFRKE

Sequences:

>Translated_128_residues
MPHFYAECTDNIRHEADLPALFARVNQALADTGIFPLAGVRSRAIWLDTWQMADGQRDYAFVHMTLKIGHGRSLESREQV
GAMLFSLITEHFAALMASRYLALSFTMEELDPVLNYKQNNVHALFRKE
>Mature_127_residues
PHFYAECTDNIRHEADLPALFARVNQALADTGIFPLAGVRSRAIWLDTWQMADGQRDYAFVHMTLKIGHGRSLESREQVG
AMLFSLITEHFAALMASRYLALSFTMEELDPVLNYKQNNVHALFRKE

Specific function: Transforms 5-carboxymethyl-2-hydroxy-muconic acid (CHM) into 5-oxo-pent-3-ene-1,2,5-tricarboxylic acid (OPET) [H]

COG id: COG3232

COG function: function code E; 5-carboxymethyl-2-hydroxymuconate isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004220
- InterPro:   IPR014347 [H]

Pfam domain/function: PF02962 CHMI [H]

EC number: =5.3.3.10 [H]

Molecular weight: Translated: 14629; Mature: 14498

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHFYAECTDNIRHEADLPALFARVNQALADTGIFPLAGVRSRAIWLDTWQMADGQRDYA
CCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHCCCCCCCCEE
FVHMTLKIGHGRSLESREQVGAMLFSLITEHFAALMASRYLALSFTMEELDPVLNYKQNN
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCC
VHALFRKE
EEEEEECC
>Mature Secondary Structure 
PHFYAECTDNIRHEADLPALFARVNQALADTGIFPLAGVRSRAIWLDTWQMADGQRDYA
CCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHCCCCCCCCEE
FVHMTLKIGHGRSLESREQVGAMLFSLITEHFAALMASRYLALSFTMEELDPVLNYKQNN
EEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCCC
VHALFRKE
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2194841; 2261999; 8547259 [H]