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The map label for this gene is scoA [H]

Identifier: 157368835

GI number: 157368835

Start: 654825

End: 655523

Strand: Direct

Name: scoA [H]

Synonym: Spro_0590

Alternate gene names: 157368835

Gene position: 654825-655523 (Clockwise)

Preceding gene: 157368830

Following gene: 157368836

Centisome position: 12.02

GC content: 61.09

Gene sequence:

>699_bases
ATGGCAGGGCTCGATAAACGCGTCGCAAGCTACCAGGAAGCGCTGGCAGGCCTGACGGACAATATGACGGTGTTGGCGGG
CGGTTTCGGCCTGTGCGGCATCCCGGAAAACCTGATTAATGAGATCCGTCGCCTGGGAGTGACCGGCCTGACGGTGGTAT
CAAACAACTGCGGCGTCGACGGCTTTGGCCTCGGTCTGCTGCTGGAAAACCGGCAGATCCGCAAGGTGGTGGCCTCCTAC
GTTGGTGAGAACGCGCTGTTCGAGCAGCAGGCGATCAGCGGTGAACTGGAAGTGGAACTGACGCCGCAGGGTTCTCTGGC
AGAAAAAATCCGTGCCGGAGGCGCCGGTATCCCGGCGTTCTTCACCGCTACTGGCTACGGCACCCCGGTGGCCGAAGGCA
AGGAGGTACGCGAGTTCAACGGGCGCCCTTACATCATGGAGCAGGCGATCACCGGTGACTTCGCCATCATCAAGGGCTGG
AAAGCCGATCACTTCGGCAATGTCATCTATCGCCACACCGCACAGAACTTTAACCCGCTGATGGCCACCGCCGGGCGAAT
CACCGTGGTGGAGGTGGAAGAGATCGTCGCACCGGGCGAACTGGATCCGGCCGCGATCCACACCCCCGGCATCTACGTTG
ACCGCCTGATCCAGGGCAGTTTCGAAAAGCGCATTGAACAGCGCACTCTGCGTACCTGA

Upstream 100 bases:

>100_bases
GCACAAAAACAAAATTAACAAATCATTTTTGTGACCTGATGATGCCTTTGCACAGGCAGGGGCATGCCGCCCACGGCCAC
AGAATACTCAGAGGCAGCCA

Downstream 100 bases:

>100_bases
GGAGAACCCCATGCTTACCCGTGAACAAATGGCGCAGCGCGTGGCACAAGAACTGCGTGACGGTGACTACGTCAATCTGG
GGATCGGCATTCCTACGCTG

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MAGLDKRVASYQEALAGLTDNMTVLAGGFGLCGIPENLINEIRRLGVTGLTVVSNNCGVDGFGLGLLLENRQIRKVVASY
VGENALFEQQAISGELEVELTPQGSLAEKIRAGGAGIPAFFTATGYGTPVAEGKEVREFNGRPYIMEQAITGDFAIIKGW
KADHFGNVIYRHTAQNFNPLMATAGRITVVEVEEIVAPGELDPAAIHTPGIYVDRLIQGSFEKRIEQRTLRT

Sequences:

>Translated_232_residues
MAGLDKRVASYQEALAGLTDNMTVLAGGFGLCGIPENLINEIRRLGVTGLTVVSNNCGVDGFGLGLLLENRQIRKVVASY
VGENALFEQQAISGELEVELTPQGSLAEKIRAGGAGIPAFFTATGYGTPVAEGKEVREFNGRPYIMEQAITGDFAIIKGW
KADHFGNVIYRHTAQNFNPLMATAGRITVVEVEEIVAPGELDPAAIHTPGIYVDRLIQGSFEKRIEQRTLRT
>Mature_231_residues
AGLDKRVASYQEALAGLTDNMTVLAGGFGLCGIPENLINEIRRLGVTGLTVVSNNCGVDGFGLGLLLENRQIRKVVASYV
GENALFEQQAISGELEVELTPQGSLAEKIRAGGAGIPAFFTATGYGTPVAEGKEVREFNGRPYIMEQAITGDFAIIKGWK
ADHFGNVIYRHTAQNFNPLMATAGRITVVEVEEIVAPGELDPAAIHTPGIYVDRLIQGSFEKRIEQRTLRT

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=238, Percent_Identity=60.5042016806723, Blast_Score=283, Evalue=1e-76,
Organism=Homo sapiens, GI11545841, Length=244, Percent_Identity=55.327868852459, Blast_Score=248, Evalue=3e-66,
Organism=Escherichia coli, GI1788551, Length=214, Percent_Identity=40.6542056074766, Blast_Score=176, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17531517, Length=239, Percent_Identity=54.3933054393305, Blast_Score=262, Evalue=1e-70,
Organism=Drosophila melanogaster, GI21358325, Length=234, Percent_Identity=51.2820512820513, Blast_Score=238, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24655794, Length=234, Percent_Identity=51.2820512820513, Blast_Score=238, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 24965; Mature: 24834

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLDKRVASYQEALAGLTDNMTVLAGGFGLCGIPENLINEIRRLGVTGLTVVSNNCGVD
CCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCC
GFGLGLLLENRQIRKVVASYVGENALFEQQAISGELEVELTPQGSLAEKIRAGGAGIPAF
CEEEEEEECCHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCE
FTATGYGTPVAEGKEVREFNGRPYIMEQAITGDFAIIKGWKADHFGNVIYRHTAQNFNPL
EEECCCCCCCCCCCHHHHCCCCCEEEEHHCCCCEEEEECCCCCCCCCEEEEECCCCCCHH
MATAGRITVVEVEEIVAPGELDPAAIHTPGIYVDRLIQGSFEKRIEQRTLRT
HHCCCCEEEEEHHHHCCCCCCCCCEEECCCHHHHHHHHCHHHHHHHHHHCCC
>Mature Secondary Structure 
AGLDKRVASYQEALAGLTDNMTVLAGGFGLCGIPENLINEIRRLGVTGLTVVSNNCGVD
CCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCC
GFGLGLLLENRQIRKVVASYVGENALFEQQAISGELEVELTPQGSLAEKIRAGGAGIPAF
CEEEEEEECCHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCE
FTATGYGTPVAEGKEVREFNGRPYIMEQAITGDFAIIKGWKADHFGNVIYRHTAQNFNPL
EEECCCCCCCCCCCHHHHCCCCCEEEEHHCCCCEEEEECCCCCCCCCEEEEECCCCCCHH
MATAGRITVVEVEEIVAPGELDPAAIHTPGIYVDRLIQGSFEKRIEQRTLRT
HHCCCCEEEEEHHHHCCCCCCCCCEEECCCHHHHHHHHCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]