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The map label for this gene is nahA [H]

Identifier: 157368783

GI number: 157368783

Start: 592234

End: 594627

Strand: Direct

Name: nahA [H]

Synonym: Spro_0536

Alternate gene names: 157368783

Gene position: 592234-594627 (Clockwise)

Preceding gene: 157368782

Following gene: 157368795

Centisome position: 10.87

GC content: 60.74

Gene sequence:

>2394_bases
ATGCACAGATCTCTGCGTTATACGCTACTGGCTTCATCGTTATTGCTTTCCCTGGGCGCGCTGGCGCAGCCGGCCGGCGA
TTTGCCGCTGATGCCCTGGCCGCAGCAGGTGGAACTGACCCAACCGGCGGGCAGGCTGGTGCTGGACCACCGTTTGTCGA
TTAACCTGCAGGGTGACGATTTGGGTGATGCGCTGCCGCGCTGGCGGCAACGTATTGAGCTGCAAACCGGTTGGACGCTG
GCACCGCAGGCGGCAAAAGCCGCAGGCGTGGTGATTAACGTGAACATCAAAGACAAGGTGGCGGCGCAGCCGCTGCCGGG
CAGCGACGAGAGCTATAAACTGCTGGTGATGCAGGATGGCGTCACCCTGACCGCCAATACCCGTTTCGGTGCGCTGCGTG
GCATGGAAACCCTGCTGCAACTGGTGCAGACCGACGGCCAGAACACCTTCCTGCCGCTGGTGAGTATCACCGACGTACCG
CGTTTCCCGTGGCGCGGCGTGCTGCTGGATTCGGCGCGTCATTTCCTGCCGCTGGCGGATATTCTGCGCCAGCTCGACGG
CATGGCGGCAGCCAAGCTCAACGTGTTTCACTGGCACCTGACCGACGATCAGGGTTGGCGTTTTGCTTCTGAGCATTATC
CCAAGCTGCAACAGCAGGCCAGCGACGGCCAGTTTTATACTCGCGAACAGATGCAACAGGTGGTGGCCTATGCCACCGCG
CGCGGCATCCGGGTGGTGCCGGAAATCGATCTGCCGGGTCATGCTTCCAGCATCGCCGTGGCTTACCCGGAGCTGATGAG
CGCGCCGGGGCCGTATCAGATGGAGCGCAAGTGGGGTGTCCATAAGCCAACGCTCGATCCGACCCGTGAAGAAGTTTATC
AATTTGTAGACGCTATTATTGGCGAACTGGCGGCGATCTTCCCCGATCCTTACCTGCATATTGGCGGTGACGAGGTGGAT
GCCAGCCAATGGAAGCAATCGAAAACCATTCAGGCCTTTATGCAGCAACATCAGTTGGCGGACATCCATGCATTGCAGGC
CTACTTCAACCAGAAGCTGGAAAAAATCCTCGAACAGCACCAACGGCAGATGGTCGGTTGGGATGAGATTTATCACCCGT
CGCTACCACGCAGCATTGTGATCCAATCCTGGCAGGGTCAGGACTCACTGGGGGCCAGCGCGCAGGACGGCTATCAGGGC
ATTCTGTCCACCGGCTTCTACCTCGATCAACCACAGAGCAGCGCCTATCACTATCGCAACGAGATCCTGCCGCAGCCGCT
GGGCGTCGCCACCGAGGTGCAGCCCGATGAAAAGGCGCAGAGCTGGCAGTTCAGCATGCCGCGACTGAAGGGCAGCGCGG
TGGAGGGCAGTTTTACCCTGATTGAAGGCAAACAAGGCTGGCGTGGCTTTATCGACTTCAACGGCAAATCTCGCCGTGCA
TTGCAGGATATCGTCTGGCGTTCTCCGCAGCAGGTGAGCTTCCGCGTCGATACCTGGATGGGCGAGACGCGTCCGGTGTT
CACGCTGCAGCAGGATAAGCTCAGTGGGTATACGCTGGTTGGCAACGTGCGTTACCCGACCAGCGGCGGCAAGCTGACGG
CGATCCCGGCGGGCAAGATGCCGGTGGTACCGGACGCGAAGCAGCAGAGCAATATTCTTGGCGGCGAGGCGGCGCTGTGG
GCGGAAAACATCAGGGCGCCGATCCTCGATCTCAAGCTGTGGCCGCGCGGGTTCGCGGTGGCGGAGCGCTTGTGGTCGGC
ACAGGACGTAACCGATGAAAACAACATGTACCGGCGGCTGGCGGCAGTTGACGCCTGGTCGGTGGTGTCGGTGGGCTTGC
AGCAGCATGCAGAGACCGCCCGCGAATTCACCCGGCTGGCGAACAGCGTGCAGATTGCACCGCTGCAAACCCTGGCCGAG
GCGGTCGAGCCGGGCCAGTACTACACCCGTCAGCATCTGAAATTCAAGGCCGGTAATTATCACCAGTTCGAACCGCTGAA
TCGCTTTGCCGACGCTCTGCCGGCGGAAAGCAACGCAGTGCGCGAGATGGGGCTGCAGGTCGCGGCCCTGGTGAAAGATC
GCAATAACAGTGCGGCGGCACAGGCGCTGCGCGAACGTTTGCAACGCTGGCAGTTGAATACCGCGCCGGTGAAAACGGTG
ATTGCCGGTAACCGGGTGATGCAGGATCTGGCTCCGGTAGCGCAGGATGTCGGCGCGCTGGCGGCACTGGGGCTGATGCT
GCTGGAACGTTATCAGCAGAACAAACCCTTGAGCAAAGCCGAAGCCGGGCAAATACAGCAACAGCTGGATACGGCGGCGC
AAATACGTGACGAAGTGGTGATTGCGGCGGTTTATCCGCTGGAAGCCCTGCTGCGTGCCAGCGCGATCGAATAA

Upstream 100 bases:

>100_bases
ACCCGGCTTTTCACCCTCGCCGTTGGACATCTGTACTGTGCTCAGTCTTTATTTATAGCTTCGCTGTTTTTATTGATTTT
TTTCCTCTGAGGAATTTCTG

Downstream 100 bases:

>100_bases
TTTTCTGCCTCGTCGGGCTCAGCATGCGTAGGGGCTCTGCATGCCGAGCCCTCACAGCACCTACAGCTGCAGCGGCGGCA
ACTGTTTGAAAATGCTGACC

Product: beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 797; Mature: 797

Protein sequence:

>797_residues
MHRSLRYTLLASSLLLSLGALAQPAGDLPLMPWPQQVELTQPAGRLVLDHRLSINLQGDDLGDALPRWRQRIELQTGWTL
APQAAKAAGVVINVNIKDKVAAQPLPGSDESYKLLVMQDGVTLTANTRFGALRGMETLLQLVQTDGQNTFLPLVSITDVP
RFPWRGVLLDSARHFLPLADILRQLDGMAAAKLNVFHWHLTDDQGWRFASEHYPKLQQQASDGQFYTREQMQQVVAYATA
RGIRVVPEIDLPGHASSIAVAYPELMSAPGPYQMERKWGVHKPTLDPTREEVYQFVDAIIGELAAIFPDPYLHIGGDEVD
ASQWKQSKTIQAFMQQHQLADIHALQAYFNQKLEKILEQHQRQMVGWDEIYHPSLPRSIVIQSWQGQDSLGASAQDGYQG
ILSTGFYLDQPQSSAYHYRNEILPQPLGVATEVQPDEKAQSWQFSMPRLKGSAVEGSFTLIEGKQGWRGFIDFNGKSRRA
LQDIVWRSPQQVSFRVDTWMGETRPVFTLQQDKLSGYTLVGNVRYPTSGGKLTAIPAGKMPVVPDAKQQSNILGGEAALW
AENIRAPILDLKLWPRGFAVAERLWSAQDVTDENNMYRRLAAVDAWSVVSVGLQQHAETAREFTRLANSVQIAPLQTLAE
AVEPGQYYTRQHLKFKAGNYHQFEPLNRFADALPAESNAVREMGLQVAALVKDRNNSAAAQALRERLQRWQLNTAPVKTV
IAGNRVMQDLAPVAQDVGALAALGLMLLERYQQNKPLSKAEAGQIQQQLDTAAQIRDEVVIAAVYPLEALLRASAIE

Sequences:

>Translated_797_residues
MHRSLRYTLLASSLLLSLGALAQPAGDLPLMPWPQQVELTQPAGRLVLDHRLSINLQGDDLGDALPRWRQRIELQTGWTL
APQAAKAAGVVINVNIKDKVAAQPLPGSDESYKLLVMQDGVTLTANTRFGALRGMETLLQLVQTDGQNTFLPLVSITDVP
RFPWRGVLLDSARHFLPLADILRQLDGMAAAKLNVFHWHLTDDQGWRFASEHYPKLQQQASDGQFYTREQMQQVVAYATA
RGIRVVPEIDLPGHASSIAVAYPELMSAPGPYQMERKWGVHKPTLDPTREEVYQFVDAIIGELAAIFPDPYLHIGGDEVD
ASQWKQSKTIQAFMQQHQLADIHALQAYFNQKLEKILEQHQRQMVGWDEIYHPSLPRSIVIQSWQGQDSLGASAQDGYQG
ILSTGFYLDQPQSSAYHYRNEILPQPLGVATEVQPDEKAQSWQFSMPRLKGSAVEGSFTLIEGKQGWRGFIDFNGKSRRA
LQDIVWRSPQQVSFRVDTWMGETRPVFTLQQDKLSGYTLVGNVRYPTSGGKLTAIPAGKMPVVPDAKQQSNILGGEAALW
AENIRAPILDLKLWPRGFAVAERLWSAQDVTDENNMYRRLAAVDAWSVVSVGLQQHAETAREFTRLANSVQIAPLQTLAE
AVEPGQYYTRQHLKFKAGNYHQFEPLNRFADALPAESNAVREMGLQVAALVKDRNNSAAAQALRERLQRWQLNTAPVKTV
IAGNRVMQDLAPVAQDVGALAALGLMLLERYQQNKPLSKAEAGQIQQQLDTAAQIRDEVVIAAVYPLEALLRASAIE
>Mature_797_residues
MHRSLRYTLLASSLLLSLGALAQPAGDLPLMPWPQQVELTQPAGRLVLDHRLSINLQGDDLGDALPRWRQRIELQTGWTL
APQAAKAAGVVINVNIKDKVAAQPLPGSDESYKLLVMQDGVTLTANTRFGALRGMETLLQLVQTDGQNTFLPLVSITDVP
RFPWRGVLLDSARHFLPLADILRQLDGMAAAKLNVFHWHLTDDQGWRFASEHYPKLQQQASDGQFYTREQMQQVVAYATA
RGIRVVPEIDLPGHASSIAVAYPELMSAPGPYQMERKWGVHKPTLDPTREEVYQFVDAIIGELAAIFPDPYLHIGGDEVD
ASQWKQSKTIQAFMQQHQLADIHALQAYFNQKLEKILEQHQRQMVGWDEIYHPSLPRSIVIQSWQGQDSLGASAQDGYQG
ILSTGFYLDQPQSSAYHYRNEILPQPLGVATEVQPDEKAQSWQFSMPRLKGSAVEGSFTLIEGKQGWRGFIDFNGKSRRA
LQDIVWRSPQQVSFRVDTWMGETRPVFTLQQDKLSGYTLVGNVRYPTSGGKLTAIPAGKMPVVPDAKQQSNILGGEAALW
AENIRAPILDLKLWPRGFAVAERLWSAQDVTDENNMYRRLAAVDAWSVVSVGLQQHAETAREFTRLANSVQIAPLQTLAE
AVEPGQYYTRQHLKFKAGNYHQFEPLNRFADALPAESNAVREMGLQVAALVKDRNNSAAAQALRERLQRWQLNTAPVKTV
IAGNRVMQDLAPVAQDVGALAALGLMLLERYQQNKPLSKAEAGQIQQQLDTAAQIRDEVVIAAVYPLEALLRASAIE

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=329, Percent_Identity=35.258358662614, Blast_Score=211, Evalue=3e-54,
Organism=Homo sapiens, GI189181666, Length=438, Percent_Identity=33.5616438356164, Blast_Score=211, Evalue=3e-54,
Organism=Caenorhabditis elegans, GI17569815, Length=370, Percent_Identity=34.8648648648649, Blast_Score=197, Evalue=3e-50,
Organism=Drosophila melanogaster, GI24657468, Length=353, Percent_Identity=32.2946175637394, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI17647501, Length=353, Percent_Identity=32.2946175637394, Blast_Score=155, Evalue=1e-37,
Organism=Drosophila melanogaster, GI281365639, Length=353, Percent_Identity=32.2946175637394, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24657474, Length=353, Percent_Identity=32.2946175637394, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI17933586, Length=364, Percent_Identity=33.2417582417582, Blast_Score=145, Evalue=1e-34,
Organism=Drosophila melanogaster, GI45551090, Length=280, Percent_Identity=32.8571428571429, Blast_Score=134, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24653074, Length=280, Percent_Identity=32.8571428571429, Blast_Score=134, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 88801; Mature: 88801

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRSLRYTLLASSLLLSLGALAQPAGDLPLMPWPQQVELTQPAGRLVLDHRLSINLQGDD
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEEEEECCCC
LGDALPRWRQRIELQTGWTLAPQAAKAAGVVINVNIKDKVAAQPLPGSDESYKLLVMQDG
HHHHHHHHHHHEECCCCCEECCCHHHHCCEEEEECCCHHHCCCCCCCCCCCEEEEEEECC
VTLTANTRFGALRGMETLLQLVQTDGQNTFLPLVSITDVPRFPWRGVLLDSARHFLPLAD
EEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCHHH
ILRQLDGMAAAKLNVFHWHLTDDQGWRFASEHYPKLQQQASDGQFYTREQMQQVVAYATA
HHHHHCCCCEEEEEEEEEEEECCCCCEEHHHHCHHHHHHCCCCCCHHHHHHHHHHHHHHH
RGIRVVPEIDLPGHASSIAVAYPELMSAPGPYQMERKWGVHKPTLDPTREEVYQFVDAII
CCEEEEECCCCCCCCCCEEEECHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHH
GELAAIFPDPYLHIGGDEVDASQWKQSKTIQAFMQQHQLADIHALQAYFNQKLEKILEQH
HHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRQMVGWDEIYHPSLPRSIVIQSWQGQDSLGASAQDGYQGILSTGFYLDQPQSSAYHYRN
HHHHCCHHHHCCCCCCHHHEEECCCCCCCCCCCCCHHHHHHHHCCEEECCCCCHHHHHHH
EILPQPLGVATEVQPDEKAQSWQFSMPRLKGSAVEGSFTLIEGKQGWRGFIDFNGKSRRA
HCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCHHHH
LQDIVWRSPQQVSFRVDTWMGETRPVFTLQQDKLSGYTLVGNVRYPTSGGKLTAIPAGKM
HHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCEEEEECCCCC
PVVPDAKQQSNILGGEAALWAENIRAPILDLKLWPRGFAVAERLWSAQDVTDENNMYRRL
CCCCCCHHHCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCHHHHHHH
AAVDAWSVVSVGLQQHAETAREFTRLANSVQIAPLQTLAEAVEPGQYYTRQHLKFKAGNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHCCCHHHHHHHHEEECCCC
HQFEPLNRFADALPAESNAVREMGLQVAALVKDRNNSAAAQALRERLQRWQLNTAPVKTV
CCCCHHHHHHHHCCCCCHHHHHHHHHHEEHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHH
IAGNRVMQDLAPVAQDVGALAALGLMLLERYQQNKPLSKAEAGQIQQQLDTAAQIRDEVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCEE
IAAVYPLEALLRASAIE
EEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MHRSLRYTLLASSLLLSLGALAQPAGDLPLMPWPQQVELTQPAGRLVLDHRLSINLQGDD
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEEEEECCCC
LGDALPRWRQRIELQTGWTLAPQAAKAAGVVINVNIKDKVAAQPLPGSDESYKLLVMQDG
HHHHHHHHHHHEECCCCCEECCCHHHHCCEEEEECCCHHHCCCCCCCCCCCEEEEEEECC
VTLTANTRFGALRGMETLLQLVQTDGQNTFLPLVSITDVPRFPWRGVLLDSARHFLPLAD
EEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHCCHHH
ILRQLDGMAAAKLNVFHWHLTDDQGWRFASEHYPKLQQQASDGQFYTREQMQQVVAYATA
HHHHHCCCCEEEEEEEEEEEECCCCCEEHHHHCHHHHHHCCCCCCHHHHHHHHHHHHHHH
RGIRVVPEIDLPGHASSIAVAYPELMSAPGPYQMERKWGVHKPTLDPTREEVYQFVDAII
CCEEEEECCCCCCCCCCEEEECHHHHCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHH
GELAAIFPDPYLHIGGDEVDASQWKQSKTIQAFMQQHQLADIHALQAYFNQKLEKILEQH
HHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRQMVGWDEIYHPSLPRSIVIQSWQGQDSLGASAQDGYQGILSTGFYLDQPQSSAYHYRN
HHHHCCHHHHCCCCCCHHHEEECCCCCCCCCCCCCHHHHHHHHCCEEECCCCCHHHHHHH
EILPQPLGVATEVQPDEKAQSWQFSMPRLKGSAVEGSFTLIEGKQGWRGFIDFNGKSRRA
HCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCHHHH
LQDIVWRSPQQVSFRVDTWMGETRPVFTLQQDKLSGYTLVGNVRYPTSGGKLTAIPAGKM
HHHHHCCCCCCEEEEEECCCCCCCCEEEEECCCCCCEEEEEEEECCCCCCEEEEECCCCC
PVVPDAKQQSNILGGEAALWAENIRAPILDLKLWPRGFAVAERLWSAQDVTDENNMYRRL
CCCCCCHHHCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHHCCCCCCCCHHHHHHH
AAVDAWSVVSVGLQQHAETAREFTRLANSVQIAPLQTLAEAVEPGQYYTRQHLKFKAGNY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHCCCHHHHHHHHEEECCCC
HQFEPLNRFADALPAESNAVREMGLQVAALVKDRNNSAAAQALRERLQRWQLNTAPVKTV
CCCCHHHHHHHHCCCCCHHHHHHHHHHEEHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHH
IAGNRVMQDLAPVAQDVGALAALGLMLLERYQQNKPLSKAEAGQIQQQLDTAAQIRDEVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCEE
IAAVYPLEALLRASAIE
EEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]