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The map label for this gene is rsgA

Identifier: 157368670

GI number: 157368670

Start: 472660

End: 473709

Strand: Reverse

Name: rsgA

Synonym: Spro_0423

Alternate gene names: 157368670

Gene position: 473709-472660 (Counterclockwise)

Preceding gene: 157368672

Following gene: 157368669

Centisome position: 8.69

GC content: 58.0

Gene sequence:

>1050_bases
GTGAGCAAGAACAAACTGTCCAAAGGTCAAGAACGCCGCGTGCAGGCGAACCATCAACGTCGCCTGAAGCGCACTGACAA
CAAACCGGAACTGGATGATTCCCAACTGGGTGAACCGCAGGACGGCATCGTCATCAGTCGTTTCGGCATGCACGCCGACG
TTGAAGCAGCGGATGGCACTCAGCACCGCTGTAACATCCGCCGTACGTTACGTTCGCTGGTGACCGGCGATCGTGTGGTA
TGGCGCCCTGGCGTCGGCACCCATGCCGGGGTGAAGGGCATCGTAGAGGCCGTGCATGAACGCACTTCCGTACTGAACCG
CCCCGACATCTACGACGGCGTGAAGCCCATCGCCGCCAATATCGATCAGATCGTCATCGTCTCCGCCATCCTGCCAGAGC
TGTCGCTGAATATGATCGACCGCTATCTGGTGGCCTGTGAAACGCTGGAAGTCGAGCCGCTGATCGTACTGAACAAAATC
GATTTACTGGATGCCGAAGCACGCAAGACCGTCGACGGGATGATGGATATCTACCGCCATATCGGCTACCGGGTGCTGGA
AGTCTCCAGCCAGACGCGTGAAGGCATGGAGGCGTTTGAACAAGCGCTGGCCGACCGTATCAGTATCTTTGCCGGCCAGT
CCGGGGTGGGTAAATCCAGCCTGCTGAACGCCCTGCTGCCACCGAGCGATAAGCAAATTCTGGTAAATCAGGTTTCCGAT
GTCTCTGGCCTCGGGCAACATACCACCACCGCTGCGCGGCTGTACCATTTCCAGCACGGCGGCGATGTGATCGATTCACC
GGGTGTGCGTGAGTTTGGTCTGTGGCATCTGGAGCCGGAACAAGTGACTCAAGCCTATGTCGAATTCCGTGACTATTTGG
GCGGTTGCAAATTCCGCGACTGCCGCCACGATACCGACCCAGGCTGCGCCATCCGCGGGGCGATGGAGAAAGGCGATATC
GCGAAAGAGCGTTTCGAAAACTACCATCGCATTCTGGAAAGCATGGCCTCAGTGAAGGTTCGCAAGAACTTCACCGACGC
CGCAGGCTGA

Upstream 100 bases:

>100_bases
GCTGCACGTGGCGGCTAACAACGGTTATTTAATATAAAATAGCGTGTATCATAGTCCTTTTGGTCGCCATGAGCGATAAA
GCGGATTCAAGTGAGGCGCA

Downstream 100 bases:

>100_bases
TAATACCGGGCGGCGTTGACTGTGGCGGAGCCACGGTTACAATGCGCGCCCTTTACCCCGATTCACGAGGTTAATGTGCT
GGATAGCATCAAAATTAAAT

Product: ribosome-associated GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSKNKLSKGQERRVQANHQRRLKRTDNKPELDDSQLGEPQDGIVISRFGMHADVEAADGTQHRCNIRRTLRSLVTGDRVV
WRPGVGTHAGVKGIVEAVHERTSVLNRPDIYDGVKPIAANIDQIVIVSAILPELSLNMIDRYLVACETLEVEPLIVLNKI
DLLDAEARKTVDGMMDIYRHIGYRVLEVSSQTREGMEAFEQALADRISIFAGQSGVGKSSLLNALLPPSDKQILVNQVSD
VSGLGQHTTTAARLYHFQHGGDVIDSPGVREFGLWHLEPEQVTQAYVEFRDYLGGCKFRDCRHDTDPGCAIRGAMEKGDI
AKERFENYHRILESMASVKVRKNFTDAAG

Sequences:

>Translated_349_residues
MSKNKLSKGQERRVQANHQRRLKRTDNKPELDDSQLGEPQDGIVISRFGMHADVEAADGTQHRCNIRRTLRSLVTGDRVV
WRPGVGTHAGVKGIVEAVHERTSVLNRPDIYDGVKPIAANIDQIVIVSAILPELSLNMIDRYLVACETLEVEPLIVLNKI
DLLDAEARKTVDGMMDIYRHIGYRVLEVSSQTREGMEAFEQALADRISIFAGQSGVGKSSLLNALLPPSDKQILVNQVSD
VSGLGQHTTTAARLYHFQHGGDVIDSPGVREFGLWHLEPEQVTQAYVEFRDYLGGCKFRDCRHDTDPGCAIRGAMEKGDI
AKERFENYHRILESMASVKVRKNFTDAAG
>Mature_348_residues
SKNKLSKGQERRVQANHQRRLKRTDNKPELDDSQLGEPQDGIVISRFGMHADVEAADGTQHRCNIRRTLRSLVTGDRVVW
RPGVGTHAGVKGIVEAVHERTSVLNRPDIYDGVKPIAANIDQIVIVSAILPELSLNMIDRYLVACETLEVEPLIVLNKID
LLDAEARKTVDGMMDIYRHIGYRVLEVSSQTREGMEAFEQALADRISIFAGQSGVGKSSLLNALLPPSDKQILVNQVSDV
SGLGQHTTTAARLYHFQHGGDVIDSPGVREFGLWHLEPEQVTQAYVEFRDYLGGCKFRDCRHDTDPGCAIRGAMEKGDIA
KERFENYHRILESMASVKVRKNFTDAAG

Specific function: May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover

COG id: COG1162

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 engC GTPase domain

Homologues:

Organism=Escherichia coli, GI87082381, Length=349, Percent_Identity=77.9369627507163, Blast_Score=557, Evalue=1e-160,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSGA_SERP5 (A8G8U1)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476659.1
- ProteinModelPortal:   A8G8U1
- SMR:   A8G8U1
- STRING:   A8G8U1
- GeneID:   5602464
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0423
- eggNOG:   COG1162
- HOGENOM:   HBG652450
- OMA:   FRDCKHL
- ProtClustDB:   PRK12288
- BioCyc:   SPRO399741:SPRO_0423-MONOMER
- HAMAP:   MF_01820
- InterPro:   IPR010914
- InterPro:   IPR004881
- TIGRFAMs:   TIGR00157

Pfam domain/function: PF03193 DUF258

EC number: NA

Molecular weight: Translated: 38865; Mature: 38733

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS50936 ENGC_GTPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKNKLSKGQERRVQANHQRRLKRTDNKPELDDSQLGEPQDGIVISRFGMHADVEAADGT
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCC
QHRCNIRRTLRSLVTGDRVVWRPGVGTHAGVKGIVEAVHERTSVLNRPDIYDGVKPIAAN
HHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHC
IDQIVIVSAILPELSLNMIDRYLVACETLEVEPLIVLNKIDLLDAEARKTVDGMMDIYRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHCHHHHHHHHHHHHHHHH
IGYRVLEVSSQTREGMEAFEQALADRISIFAGQSGVGKSSLLNALLPPSDKQILVNQVSD
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHH
VSGLGQHTTTAARLYHFQHGGDVIDSPGVREFGLWHLEPEQVTQAYVEFRDYLGGCKFRD
HHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCC
CRHDTDPGCAIRGAMEKGDIAKERFENYHRILESMASVKVRKNFTDAAG
CCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SKNKLSKGQERRVQANHQRRLKRTDNKPELDDSQLGEPQDGIVISRFGMHADVEAADGT
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCC
QHRCNIRRTLRSLVTGDRVVWRPGVGTHAGVKGIVEAVHERTSVLNRPDIYDGVKPIAAN
HHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHC
IDQIVIVSAILPELSLNMIDRYLVACETLEVEPLIVLNKIDLLDAEARKTVDGMMDIYRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHCHHHHHHHHHHHHHHHH
IGYRVLEVSSQTREGMEAFEQALADRISIFAGQSGVGKSSLLNALLPPSDKQILVNQVSD
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHH
VSGLGQHTTTAARLYHFQHGGDVIDSPGVREFGLWHLEPEQVTQAYVEFRDYLGGCKFRD
HHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCC
CRHDTDPGCAIRGAMEKGDIAKERFENYHRILESMASVKVRKNFTDAAG
CCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA