Click here to switch to the map view.

The map label for this gene is bcsB [H]

Identifier: 157368398

GI number: 157368398

Start: 161602

End: 163911

Strand: Direct

Name: bcsB [H]

Synonym: Spro_0149

Alternate gene names: 157368398

Gene position: 161602-163911 (Clockwise)

Preceding gene: 157368397

Following gene: 157368399

Centisome position: 2.97

GC content: 59.83

Gene sequence:

>2310_bases
ATGACGAGAAAAATAACCTGGTTTACCGCCCTGGCCTTAGGCATCAGCACCCTGTCTCAGGCTGAAACTGCCACCGCGCC
GACCGTTGCCGCACAACCGCCGCTGGCGGTGCCAGCCGACGCAGCGGTTACGACACCCATGGGATCGGTCGCGCCGCAGG
ATCCGAATGCGCCGGTGCGTGACGTGCAATTGCCGTTTGCCAAGATTGCGCCGCCGCCGGGCACCTTTACCCTGCGTGGC
ACCCGGCCGGATGGCCAGGTCGAATTCGGTGTGCGCAGCGATGAAGTGGTGTCGCAGGCGATGCTCGACCTGGAATTCAC
CCCGTCACCTTCGCTGATCCCGGTGGAGTCGCACGTCAAGGTGTACCTCAATGACGAACTGATGGGGGTGACCACTCTCG
CCAAAGAGCAGCTCGGCAAACCCAATCGTATCCAGATGGCGATCGATCCGCGCTATATCACCGATTTTAACCGTGTGCGG
CTGGTGTTCGTTGGTCATTACCAGAACATTTGTGAAAACCCGGCCAGCACCACGCTGTGGCTCGAAGTCAGCAAATCCAG
TTCGTTGAATCTACGCTACCAAACCCTGCCGGTGAAAAACGAGCTTTCGCATTTCCCGGAGCCGTTCTTCGACAGTCGCG
ACAACCGGCCGCTGACCTTGCCAATGGTGTTTGCCGGCCAGCCGGATATCACCCAGCAGCGGGCTGCGGGCATTCTGGCC
TCGTGGTTCGGCAGCAAAGCGCAGTGGCGCGGCCAGTCGTTCCCGACGCTGTATAACAAGCTGCCGGAGCAGCATGCCAT
CGTTTTTGCCACCAATAAGCAGCGCCCGGACTTCCTGCGCGATTATCCGCCGGTCAACGGCCCGACGGTGGAGATGATCA
GCCATCCGGATAATCCGTACATCAAGCTGCTGCTGGTGCAGGGCCGTGACGACAACGATTTGATCACCGCCGTGAAAGGC
ATTGCGCAGGGTAACATCCTGTTCCGTGGCCAGAATGTTACGGTGGACAAGGTCGAACAACTGGCGCCGCGCCAGCCGTA
TGACGCGCCTAACTGGGTGCGTACCGACAGGCCAATGACCTTTGCCGAGCTGCAGCAGTATGCTGAACAACTGCAGACCA
GCGGCATTGAGCCGGGCCCGATCTCGCTGACCATGAATCTGCCGCCGGACCTGTTCCTGATCCGCAGTACCGGCATTGAT
ATGCATCTGAAATATCACTACACCGCGCCGCGCATTCAGGACGGTTCGCGCCTGAGCGTTAGCCTGAACAACCAGTTTGT
GCAGGCCTATTCGCTGGTGCCGGAGCATGAGCAGGGCGCTCAACTGTTACGTTTGCCACTGACCCAGGGGCTGATCGACT
CGGACAAGAGCGTCAATATCCCGGCGCTGCGGCTGGGAGCCACCAACCAACTGCGTTTCGACTTTGACTACACCACCCTG
CTCGCCAGCGGTGCCGAAGGACGCTGTGAAACCTATTCCTTTACCGCCAACCATGCGGTGATCGACGGTTCATCGACCAT
TGATTTCTCCGGTTACCGCCACTTTATGGCGATGCCGGATCTGCGTGCCTTTGCCAATGCCGGTTTCCCTTTCAGCCGTT
TGGCCGATCTGTCGCAGACCCTGGTGCTGGTGAACAAGCAGCCACAGCCATCGCAGGTCAGCGCATTGCTGAACGCGATG
GGCGTTATCGGCGCTCAGACCGGTTATCCGGCGCTGGCGGTGACGGTGAGTGACGACTGGTCGCAGGCCAAGGAACGCGA
TGCCGATATTCTGATGATCGGCACTATTCCGCCGGAACTGCGGGACGACAAAAAAATCAACCTGCTGGTGGATGCCACCC
AGAGCTGGGTGAAGCAGCCGACGCGGCAGTTACCGCTGCCGACCATGGACGTGCTGGCGGAGGATACCAAGGCGGACAGC
AAAACCACCATCAGTTCAGAAGGGGCCATGTCGGCGATTGTTGGCGTGCAGTCACCGTTTAACGATCAGCGCAGCATTGT
GGCGTTACTGGCCGACAGCCCGCGTGGCTACGACCTGCTCAACAATGCACTTCTGGACAGTGGCAAGCGTGCGGCGGTGT
TTGGTTCGGTGGCGGTGATCCGGGAATCCGGGGTGAACAGCCTGCGCGTGGGCGACGTTTATTATGTCGGTCACCTGCCG
TGGTGGGAGCGTATCTGGCATGCGCTGTCGACTCACCCGGTGTTGCTGGCAGTGATTGCGGTCGTGGTGGTGGTGATCCT
GGCGCTGTTGTTGTGGCGTGGTTTGAAAGCCTTCAGCCGTCGTCGCCTGTCGCCTGAAGATCGGGACTAA

Upstream 100 bases:

>100_bases
GTCGGCAGGGCTCCAGCCTTCAGCCAAAAAGAGACAGTGGTATAGGCAAACCGCCCGCTTACTCGCCTGGCCCCCAGGCT
CTAACATTGATGATGATACG

Downstream 100 bases:

>100_bases
TCGCTATGCCTGCGGCATTGAAGCGTCTGACCTTCGGCATGTTGCTACTGTGCTCATTCAGCGCGGTAGCCACCTGCGAG
TGGCCAGCCTGGCAACAGTA

Product: cellulose synthase regulator protein

Products: NA

Alternate protein names: Cellulose synthase regulatory subunit [H]

Number of amino acids: Translated: 769; Mature: 768

Protein sequence:

>769_residues
MTRKITWFTALALGISTLSQAETATAPTVAAQPPLAVPADAAVTTPMGSVAPQDPNAPVRDVQLPFAKIAPPPGTFTLRG
TRPDGQVEFGVRSDEVVSQAMLDLEFTPSPSLIPVESHVKVYLNDELMGVTTLAKEQLGKPNRIQMAIDPRYITDFNRVR
LVFVGHYQNICENPASTTLWLEVSKSSSLNLRYQTLPVKNELSHFPEPFFDSRDNRPLTLPMVFAGQPDITQQRAAGILA
SWFGSKAQWRGQSFPTLYNKLPEQHAIVFATNKQRPDFLRDYPPVNGPTVEMISHPDNPYIKLLLVQGRDDNDLITAVKG
IAQGNILFRGQNVTVDKVEQLAPRQPYDAPNWVRTDRPMTFAELQQYAEQLQTSGIEPGPISLTMNLPPDLFLIRSTGID
MHLKYHYTAPRIQDGSRLSVSLNNQFVQAYSLVPEHEQGAQLLRLPLTQGLIDSDKSVNIPALRLGATNQLRFDFDYTTL
LASGAEGRCETYSFTANHAVIDGSSTIDFSGYRHFMAMPDLRAFANAGFPFSRLADLSQTLVLVNKQPQPSQVSALLNAM
GVIGAQTGYPALAVTVSDDWSQAKERDADILMIGTIPPELRDDKKINLLVDATQSWVKQPTRQLPLPTMDVLAEDTKADS
KTTISSEGAMSAIVGVQSPFNDQRSIVALLADSPRGYDLLNNALLDSGKRAAVFGSVAVIRESGVNSLRVGDVYYVGHLP
WWERIWHALSTHPVLLAVIAVVVVVILALLLWRGLKAFSRRRLSPEDRD

Sequences:

>Translated_769_residues
MTRKITWFTALALGISTLSQAETATAPTVAAQPPLAVPADAAVTTPMGSVAPQDPNAPVRDVQLPFAKIAPPPGTFTLRG
TRPDGQVEFGVRSDEVVSQAMLDLEFTPSPSLIPVESHVKVYLNDELMGVTTLAKEQLGKPNRIQMAIDPRYITDFNRVR
LVFVGHYQNICENPASTTLWLEVSKSSSLNLRYQTLPVKNELSHFPEPFFDSRDNRPLTLPMVFAGQPDITQQRAAGILA
SWFGSKAQWRGQSFPTLYNKLPEQHAIVFATNKQRPDFLRDYPPVNGPTVEMISHPDNPYIKLLLVQGRDDNDLITAVKG
IAQGNILFRGQNVTVDKVEQLAPRQPYDAPNWVRTDRPMTFAELQQYAEQLQTSGIEPGPISLTMNLPPDLFLIRSTGID
MHLKYHYTAPRIQDGSRLSVSLNNQFVQAYSLVPEHEQGAQLLRLPLTQGLIDSDKSVNIPALRLGATNQLRFDFDYTTL
LASGAEGRCETYSFTANHAVIDGSSTIDFSGYRHFMAMPDLRAFANAGFPFSRLADLSQTLVLVNKQPQPSQVSALLNAM
GVIGAQTGYPALAVTVSDDWSQAKERDADILMIGTIPPELRDDKKINLLVDATQSWVKQPTRQLPLPTMDVLAEDTKADS
KTTISSEGAMSAIVGVQSPFNDQRSIVALLADSPRGYDLLNNALLDSGKRAAVFGSVAVIRESGVNSLRVGDVYYVGHLP
WWERIWHALSTHPVLLAVIAVVVVVILALLLWRGLKAFSRRRLSPEDRD
>Mature_768_residues
TRKITWFTALALGISTLSQAETATAPTVAAQPPLAVPADAAVTTPMGSVAPQDPNAPVRDVQLPFAKIAPPPGTFTLRGT
RPDGQVEFGVRSDEVVSQAMLDLEFTPSPSLIPVESHVKVYLNDELMGVTTLAKEQLGKPNRIQMAIDPRYITDFNRVRL
VFVGHYQNICENPASTTLWLEVSKSSSLNLRYQTLPVKNELSHFPEPFFDSRDNRPLTLPMVFAGQPDITQQRAAGILAS
WFGSKAQWRGQSFPTLYNKLPEQHAIVFATNKQRPDFLRDYPPVNGPTVEMISHPDNPYIKLLLVQGRDDNDLITAVKGI
AQGNILFRGQNVTVDKVEQLAPRQPYDAPNWVRTDRPMTFAELQQYAEQLQTSGIEPGPISLTMNLPPDLFLIRSTGIDM
HLKYHYTAPRIQDGSRLSVSLNNQFVQAYSLVPEHEQGAQLLRLPLTQGLIDSDKSVNIPALRLGATNQLRFDFDYTTLL
ASGAEGRCETYSFTANHAVIDGSSTIDFSGYRHFMAMPDLRAFANAGFPFSRLADLSQTLVLVNKQPQPSQVSALLNAMG
VIGAQTGYPALAVTVSDDWSQAKERDADILMIGTIPPELRDDKKINLLVDATQSWVKQPTRQLPLPTMDVLAEDTKADSK
TTISSEGAMSAIVGVQSPFNDQRSIVALLADSPRGYDLLNNALLDSGKRAAVFGSVAVIRESGVNSLRVGDVYYVGHLPW
WERIWHALSTHPVLLAVIAVVVVVILALLLWRGLKAFSRRRLSPEDRD

Specific function: Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass type I membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcsB/BcsB family [H]

Homologues:

Organism=Escherichia coli, GI1789952, Length=765, Percent_Identity=60.7843137254902, Blast_Score=982, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003920
- InterPro:   IPR018513 [H]

Pfam domain/function: PF03170 BcsB [H]

EC number: NA

Molecular weight: Translated: 84788; Mature: 84656

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKITWFTALALGISTLSQAETATAPTVAAQPPLAVPADAAVTTPMGSVAPQDPNAPVR
CCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
DVQLPFAKIAPPPGTFTLRGTRPDGQVEFGVRSDEVVSQAMLDLEFTPSPSLIPVESHVK
EEECCHHHCCCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHEEEECCCCCEEEECCCEE
VYLNDELMGVTTLAKEQLGKPNRIQMAIDPRYITDFNRVRLVFVGHYQNICENPASTTLW
EEECCCCHHHHHHHHHHCCCCCEEEEEECCCEECCCCCEEEEEEECHHHHHCCCCCEEEE
LEVSKSSSLNLRYQTLPVKNELSHFPEPFFDSRDNRPLTLPMVFAGQPDITQQRAAGILA
EEEECCCCCEEEEEECCCHHHHHHCCCCHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
SWFGSKAQWRGQSFPTLYNKLPEQHAIVFATNKQRPDFLRDYPPVNGPTVEMISHPDNPY
HHHCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCCCCHHHCCCCCCCCEEEEEECCCCCE
IKLLLVQGRDDNDLITAVKGIAQGNILFRGQNVTVDKVEQLAPRQPYDAPNWVRTDRPMT
EEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCEECCCCCC
FAELQQYAEQLQTSGIEPGPISLTMNLPPDLFLIRSTGIDMHLKYHYTAPRIQDGSRLSV
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEECCCEEEEEEEECCCCCCCCCEEEE
SLNNQFVQAYSLVPEHEQGAQLLRLPLTQGLIDSDKSVNIPALRLGATNQLRFDFDYTTL
EECCCEEEHHHCCCCCCCCCCEEEHHHHHCCCCCCCCCCCCEEEECCCCEEEEECCHHHE
LASGAEGRCETYSFTANHAVIDGSSTIDFSGYRHFMAMPDLRAFANAGFPFSRLADLSQT
EECCCCCCCEEEEEECCCEEECCCCEEECCCCCHHHCCCCHHHHHCCCCCHHHHHHCCCE
LVLVNKQPQPSQVSALLNAMGVIGAQTGYPALAVTVSDDWSQAKERDADILMIGTIPPEL
EEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCCEEEEECCCCCC
RDDKKINLLVDATQSWVKQPTRQLPLPTMDVLAEDTKADSKTTISSEGAMSAIVGVQSPF
CCCCEEEEEEECHHHHHHCHHHHCCCCHHHHHHCCCCCCCCCEECCCCCCEEEEECCCCC
NDQRSIVALLADSPRGYDLLNNALLDSGKRAAVFGSVAVIRESGVNSLRVGDVYYVGHLP
CCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEHHEEEEHHCCCCEEEECCEEEECCCC
WWERIWHALSTHPVLLAVIAVVVVVILALLLWRGLKAFSRRRLSPEDRD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TRKITWFTALALGISTLSQAETATAPTVAAQPPLAVPADAAVTTPMGSVAPQDPNAPVR
CCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCC
DVQLPFAKIAPPPGTFTLRGTRPDGQVEFGVRSDEVVSQAMLDLEFTPSPSLIPVESHVK
EEECCHHHCCCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHEEEECCCCCEEEECCCEE
VYLNDELMGVTTLAKEQLGKPNRIQMAIDPRYITDFNRVRLVFVGHYQNICENPASTTLW
EEECCCCHHHHHHHHHHCCCCCEEEEEECCCEECCCCCEEEEEEECHHHHHCCCCCEEEE
LEVSKSSSLNLRYQTLPVKNELSHFPEPFFDSRDNRPLTLPMVFAGQPDITQQRAAGILA
EEEECCCCCEEEEEECCCHHHHHHCCCCHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHH
SWFGSKAQWRGQSFPTLYNKLPEQHAIVFATNKQRPDFLRDYPPVNGPTVEMISHPDNPY
HHHCCCCCCCCCCCCHHHHHCCCCCEEEEEECCCCCCHHHCCCCCCCCEEEEEECCCCCE
IKLLLVQGRDDNDLITAVKGIAQGNILFRGQNVTVDKVEQLAPRQPYDAPNWVRTDRPMT
EEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCEECCCCCC
FAELQQYAEQLQTSGIEPGPISLTMNLPPDLFLIRSTGIDMHLKYHYTAPRIQDGSRLSV
HHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEEEECCCEEEEEEEECCCCCCCCCEEEE
SLNNQFVQAYSLVPEHEQGAQLLRLPLTQGLIDSDKSVNIPALRLGATNQLRFDFDYTTL
EECCCEEEHHHCCCCCCCCCCEEEHHHHHCCCCCCCCCCCCEEEECCCCEEEEECCHHHE
LASGAEGRCETYSFTANHAVIDGSSTIDFSGYRHFMAMPDLRAFANAGFPFSRLADLSQT
EECCCCCCCEEEEEECCCEEECCCCEEECCCCCHHHCCCCHHHHHCCCCCHHHHHHCCCE
LVLVNKQPQPSQVSALLNAMGVIGAQTGYPALAVTVSDDWSQAKERDADILMIGTIPPEL
EEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCCEEEEECCCCCC
RDDKKINLLVDATQSWVKQPTRQLPLPTMDVLAEDTKADSKTTISSEGAMSAIVGVQSPF
CCCCEEEEEEECHHHHHHCHHHHCCCCHHHHHHCCCCCCCCCEECCCCCCEEEEECCCCC
NDQRSIVALLADSPRGYDLLNNALLDSGKRAAVFGSVAVIRESGVNSLRVGDVYYVGHLP
CCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEHHEEEEHHCCCCEEEECCEEEECCCC
WWERIWHALSTHPVLLAVIAVVVVVILALLLWRGLKAFSRRRLSPEDRD
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]