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The map label for this gene is avtA [H]

Identifier: 157368302

GI number: 157368302

Start: 52549

End: 53871

Strand: Reverse

Name: avtA [H]

Synonym: Spro_0053

Alternate gene names: 157368302

Gene position: 53871-52549 (Counterclockwise)

Preceding gene: 157368303

Following gene: 157368301

Centisome position: 0.99

GC content: 56.08

Gene sequence:

>1323_bases
ATGAACCGCATTGCGTCGGAAATTGACAGGCGGTATGGTGGGGAATTACCTGCTAAAAATAATACAGCTGCACCTATGAC
TTTTTCACTTTTCGGCGACAAATTTACCCGTTACGCGGGCATTACCCGTTTAATGGATGACCTGAACGAAGGCCTGCGCA
CCCCCGGTGCCATCATGCTCGGCGGCGGCAATCCGGCGCAAATTCCAGAGATGGAAAGCTACTTCAAACAGCTGTGTCAG
GACATGCTCGACCAGGGCAAACTGACCGAGGCGCTGTGTAACTATGACGGCCCACAGGGCAAAGACGCCCTGCTGAAAGC
ACTGGCCAAATTGCTGCGCGACGAGCTGGGCTGGCAGATCTCTCCACAGAATATTGCACTGACAAATGGCAGTCAGAGCG
CGTTTTTCTACTTGTTTAACCTGTTTGCCGGCCGCTATGCCGACGGCAGCCGCCGCCGCGTACTGTTCCCGCTGGCGCCG
GAATATATCGGCTATGCCGATGCCGGGTTGGACGAAGGGCTGTTTGTCTCGGCCAAACCCAACATCGAATTGCTGCCAGA
AGGCCAGTTCAAGTATCACGTTGATTTCGAACACCTGAACATCGGCGATGATATCGGCATGATCTGCGTATCACGCCCGA
CCAATCCGACCGGCAACGTGATCACCGACGAAGAGCTGATGAAGCTCGACCGGTTGGCGCAGCAGCGCAATATTCCGCTG
GTGATCGATAACGCCTATGGCGTGCCCTTCCCCGGCATTATCTTCAGCGACGCAACGCCGCTGTGGAACCCGAACATTAT
TCTGTGCATGAGCCTGTCGAAACTCGGCCTGCCCGGTTCGCGCTGCGGCATAGTGATCGCCGATGAAAAGACCATCAGCG
CCCTGACCAACATGAACGGCATCATTAGCCTGTCACCGGGCAGCATGGGGCCGGCGATGGCAACGGAAATGATTGAACGC
GGCGATCTGCTGCGCCTGTCCAACGAGGTGATCCGTCCGTTCTACAAACAGCGCGTCGAGCACACTATCGAGATCATTCG
CCGCTACCTGTCACCAGAGCGCTGCCTGATCCATAAACCGGAAGGGGCAATTTTCCTCTGGCTGTGGTTCAAGGATCTGC
CGATTACCACTGAATTGCTGTACCAGCGCCTGAAAAAACGTGGCGTGCTGATGGTACCCGGCCACTATTTCTTCCCTGGG
CTGGAGCATGAATGGCCGCATACCCATCAGTGCATGCGGATGAACTACGTGCCGGATCCGGAGAAAATTGAGCGTGGCGT
GGCGATCCTGGCGGAAGAGATCGAACGCGCGCACCAGGAATAA

Upstream 100 bases:

>100_bases
ATAAGGTGATGGTGGTGTGGGTCGGCGATCGGTCACAATAATTCAGCGCGATATGCTGGTAAATGGCCATCGGGCGAAGT
TTACTCCCGGTGGCTGTTTT

Downstream 100 bases:

>100_bases
TGATCCTGCCTCGCTCGATTGATTGAAAATTAACCAGAAAAGATATATGATACGTATATCGTATATCTTTTTTCTCAGAA
GGTTAATTATGGCCCGCATA

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MNRIASEIDRRYGGELPAKNNTAAPMTFSLFGDKFTRYAGITRLMDDLNEGLRTPGAIMLGGGNPAQIPEMESYFKQLCQ
DMLDQGKLTEALCNYDGPQGKDALLKALAKLLRDELGWQISPQNIALTNGSQSAFFYLFNLFAGRYADGSRRRVLFPLAP
EYIGYADAGLDEGLFVSAKPNIELLPEGQFKYHVDFEHLNIGDDIGMICVSRPTNPTGNVITDEELMKLDRLAQQRNIPL
VIDNAYGVPFPGIIFSDATPLWNPNIILCMSLSKLGLPGSRCGIVIADEKTISALTNMNGIISLSPGSMGPAMATEMIER
GDLLRLSNEVIRPFYKQRVEHTIEIIRRYLSPERCLIHKPEGAIFLWLWFKDLPITTELLYQRLKKRGVLMVPGHYFFPG
LEHEWPHTHQCMRMNYVPDPEKIERGVAILAEEIERAHQE

Sequences:

>Translated_440_residues
MNRIASEIDRRYGGELPAKNNTAAPMTFSLFGDKFTRYAGITRLMDDLNEGLRTPGAIMLGGGNPAQIPEMESYFKQLCQ
DMLDQGKLTEALCNYDGPQGKDALLKALAKLLRDELGWQISPQNIALTNGSQSAFFYLFNLFAGRYADGSRRRVLFPLAP
EYIGYADAGLDEGLFVSAKPNIELLPEGQFKYHVDFEHLNIGDDIGMICVSRPTNPTGNVITDEELMKLDRLAQQRNIPL
VIDNAYGVPFPGIIFSDATPLWNPNIILCMSLSKLGLPGSRCGIVIADEKTISALTNMNGIISLSPGSMGPAMATEMIER
GDLLRLSNEVIRPFYKQRVEHTIEIIRRYLSPERCLIHKPEGAIFLWLWFKDLPITTELLYQRLKKRGVLMVPGHYFFPG
LEHEWPHTHQCMRMNYVPDPEKIERGVAILAEEIERAHQE
>Mature_440_residues
MNRIASEIDRRYGGELPAKNNTAAPMTFSLFGDKFTRYAGITRLMDDLNEGLRTPGAIMLGGGNPAQIPEMESYFKQLCQ
DMLDQGKLTEALCNYDGPQGKDALLKALAKLLRDELGWQISPQNIALTNGSQSAFFYLFNLFAGRYADGSRRRVLFPLAP
EYIGYADAGLDEGLFVSAKPNIELLPEGQFKYHVDFEHLNIGDDIGMICVSRPTNPTGNVITDEELMKLDRLAQQRNIPL
VIDNAYGVPFPGIIFSDATPLWNPNIILCMSLSKLGLPGSRCGIVIADEKTISALTNMNGIISLSPGSMGPAMATEMIER
GDLLRLSNEVIRPFYKQRVEHTIEIIRRYLSPERCLIHKPEGAIFLWLWFKDLPITTELLYQRLKKRGVLMVPGHYFFPG
LEHEWPHTHQCMRMNYVPDPEKIERGVAILAEEIERAHQE

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=415, Percent_Identity=80.9638554216867, Blast_Score=704, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 49492; Mature: 49492

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRIASEIDRRYGGELPAKNNTAAPMTFSLFGDKFTRYAGITRLMDDLNEGLRTPGAIML
CCHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
GGGNPAQIPEMESYFKQLCQDMLDQGKLTEALCNYDGPQGKDALLKALAKLLRDELGWQI
CCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEE
SPQNIALTNGSQSAFFYLFNLFAGRYADGSRRRVLFPLAPEYIGYADAGLDEGLFVSAKP
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHCCCCCCCCCCEEEECCC
NIELLPEGQFKYHVDFEHLNIGDDIGMICVSRPTNPTGNVITDEELMKLDRLAQQRNIPL
CEEEEECCCEEEEEEEEEECCCCCCCEEEEECCCCCCCCEECHHHHHHHHHHHHHCCCCE
VIDNAYGVPFPGIIFSDATPLWNPNIILCMSLSKLGLPGSRCGIVIADEKTISALTNMNG
EEECCCCCCCCCEEECCCCCCCCCCEEEEEEHHHCCCCCCCCCEEEECCHHHHHHHCCCC
IISLSPGSMGPAMATEMIERGDLLRLSNEVIRPFYKQRVEHTIEIIRRYLSPERCLIHKP
EEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
EGAIFLWLWFKDLPITTELLYQRLKKRGVLMVPGHYFFPGLEHEWPHTHQCMRMNYVPDP
CCCEEEEEEECCCCCCHHHHHHHHHHCCEEEECCHHCCCCCCCCCCCHHHHEEECCCCCH
EKIERGVAILAEEIERAHQE
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNRIASEIDRRYGGELPAKNNTAAPMTFSLFGDKFTRYAGITRLMDDLNEGLRTPGAIML
CCHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
GGGNPAQIPEMESYFKQLCQDMLDQGKLTEALCNYDGPQGKDALLKALAKLLRDELGWQI
CCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEE
SPQNIALTNGSQSAFFYLFNLFAGRYADGSRRRVLFPLAPEYIGYADAGLDEGLFVSAKP
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHCCCCCCCCCCEEEECCC
NIELLPEGQFKYHVDFEHLNIGDDIGMICVSRPTNPTGNVITDEELMKLDRLAQQRNIPL
CEEEEECCCEEEEEEEEEECCCCCCCEEEEECCCCCCCCEECHHHHHHHHHHHHHCCCCE
VIDNAYGVPFPGIIFSDATPLWNPNIILCMSLSKLGLPGSRCGIVIADEKTISALTNMNG
EEECCCCCCCCCEEECCCCCCCCCCEEEEEEHHHCCCCCCCCCEEEECCHHHHHHHCCCC
IISLSPGSMGPAMATEMIERGDLLRLSNEVIRPFYKQRVEHTIEIIRRYLSPERCLIHKP
EEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
EGAIFLWLWFKDLPITTELLYQRLKKRGVLMVPGHYFFPGLEHEWPHTHQCMRMNYVPDP
CCCEEEEEEECCCCCCHHHHHHHHHHCCEEEECCHHCCCCCCCCCCCHHHHEEECCCCCH
EKIERGVAILAEEIERAHQE
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]