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The map label for this gene is ibpA

Identifier: 157368297

GI number: 157368297

Start: 49046

End: 49459

Strand: Direct

Name: ibpA

Synonym: Spro_0048

Alternate gene names: 157368297

Gene position: 49046-49459 (Clockwise)

Preceding gene: 157368295

Following gene: 157368298

Centisome position: 0.9

GC content: 47.1

Gene sequence:

>414_bases
ATGCGTAATTTCGATCTTTCTCCACTCTACCGTTCTGCAATTGGCTTTGACCGTTTGTTTAATGCGTTGGAGGCAGGCCA
GAGTCAGGGTAATGGCGGCTATCCTCCTTATAACGTTGAGCTGGTGGATGAAAATCATTACCGCATCGCGATCGCGGTGG
CAGGATTCGCCGAGCAAGAGCTCGAGATTACCACCCAGGATAACCTGTTGATTGTACGTGGCGCTCATAATAATGAGCCG
GCGGAAAGAACCTACTTATATCAAGGTATTGCCGAACGTAACTTTGAACGTAAATTCCAGTTGGCCGAGCATATCCAAAT
TAAAGGCGCCAAACTGGAAAACGGCCTGTTGTATATCGATATGGAACGCATCGTGCCGGAAACATTAAAACCGCGCCGGA
TAGAAATTAAGTAA

Upstream 100 bases:

>100_bases
AAATTAAGAATTCGCCGTAAGGGAATTCTGATTATTTAGCCTGTCCATGATGGAAGGCTTAATTATTAAACCTCGCTGAA
GTGCCTTAGGAGGCTGTTTT

Downstream 100 bases:

>100_bases
TTCTTATTTCATCGGCGGAATGAACCGCTGGTGCAATGAATGTTAGTTAACTGCCTGCCGTCAGGGGGCGATTAAACCTC
ATCTCGCTTCATAGAAGGAG

Product: heat shock protein IbpA

Products: NA

Alternate protein names: 16 kDa heat shock protein A

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MRNFDLSPLYRSAIGFDRLFNALEAGQSQGNGGYPPYNVELVDENHYRIAIAVAGFAEQELEITTQDNLLIVRGAHNNEP
AERTYLYQGIAERNFERKFQLAEHIQIKGAKLENGLLYIDMERIVPETLKPRRIEIK

Sequences:

>Translated_137_residues
MRNFDLSPLYRSAIGFDRLFNALEAGQSQGNGGYPPYNVELVDENHYRIAIAVAGFAEQELEITTQDNLLIVRGAHNNEP
AERTYLYQGIAERNFERKFQLAEHIQIKGAKLENGLLYIDMERIVPETLKPRRIEIK
>Mature_137_residues
MRNFDLSPLYRSAIGFDRLFNALEAGQSQGNGGYPPYNVELVDENHYRIAIAVAGFAEQELEITTQDNLLIVRGAHNNEP
AERTYLYQGIAERNFERKFQLAEHIQIKGAKLENGLLYIDMERIVPETLKPRRIEIK

Specific function: Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently ref

COG id: COG0071

COG function: function code O; Molecular chaperone (small heat shock protein)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small heat shock protein (HSP20) family

Homologues:

Organism=Escherichia coli, GI1790122, Length=136, Percent_Identity=83.0882352941177, Blast_Score=235, Evalue=8e-64,
Organism=Escherichia coli, GI87082316, Length=138, Percent_Identity=47.8260869565217, Blast_Score=130, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IBPA_SERP5 (A8G7R8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476286.1
- ProteinModelPortal:   A8G7R8
- STRING:   A8G7R8
- GeneID:   5606858
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0048
- eggNOG:   COG0071
- HOGENOM:   HBG748242
- OMA:   MRNYDLT
- ProtClustDB:   PRK10743
- BioCyc:   SPRO399741:SPRO_0048-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_02000
- InterPro:   IPR002068
- InterPro:   IPR008978

Pfam domain/function: PF00011 HSP20; SSF49764 HSP20_chap

EC number: NA

Molecular weight: Translated: 15736; Mature: 15736

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01031 HSP20

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNFDLSPLYRSAIGFDRLFNALEAGQSQGNGGYPPYNVELVDENHYRIAIAVAGFAEQE
CCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCC
LEITTQDNLLIVRGAHNNEPAERTYLYQGIAERNFERKFQLAEHIQIKGAKLENGLLYID
EEEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEEECCCEECCCEEEEE
MERIVPETLKPRRIEIK
HHHCCCCCCCCEEEEEC
>Mature Secondary Structure
MRNFDLSPLYRSAIGFDRLFNALEAGQSQGNGGYPPYNVELVDENHYRIAIAVAGFAEQE
CCCCCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCEEEEEEEECCCCCC
LEITTQDNLLIVRGAHNNEPAERTYLYQGIAERNFERKFQLAEHIQIKGAKLENGLLYID
EEEEECCCEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHEEECCCEECCCEEEEE
MERIVPETLKPRRIEIK
HHHCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA