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The map label for this gene is ttuB [H]

Identifier: 157368288

GI number: 157368288

Start: 39690

End: 41006

Strand: Direct

Name: ttuB [H]

Synonym: Spro_0039

Alternate gene names: 157368288

Gene position: 39690-41006 (Clockwise)

Preceding gene: 157368285

Following gene: 157368289

Centisome position: 0.73

GC content: 52.47

Gene sequence:

>1317_bases
ATGGATTCCAGTACTTATTCCACGACAATCAAAAGGATGAATCGGCGTATTATTCCATTTATTATGCTGCTTTATCTTAT
TGCATATATAGACAGATCTAATATTTCCATTGCTGCATTGCAGATGAATGCCGATTTGGCGCTTAGCGCCGAGATGTATG
GTATTGCCGCAGGGATTTTCTATATTTCCTACATTATTTTTGAAGTCCCCAGCAATATATTATTGAGCCGTATCGGTGCC
AAGATATGGATTGCGCGCATCATGGTCACCTGGGGCATCATCGCCGCCGGTATGAGCCTGGTACAAACGCCAACGCAACT
CTATGTGATGCGTTTTTTACTTGGTGTGGCGGAGGCCGGGTTTACCCCTGGCATTATTTATTATCTTTCCTGTTGGTATC
CGCGCAGTGACCGTGCGCGTGCCATGTCGATGTTTTACATCGGTGCAGCCCTGGCTTCGGTTATTGGCCTGCCGCTGTCC
GGCAGCATCCTGAATATGCATGGTTTATTTGACATAGCAGGGTGGCGTTGGTTGTTCCTGCTGGAAGGTATTCCGGCGGT
GTTGCTGGGCATCGTCACCTATTTTTACCTCGATGATGCGCCGCAACAGGCAAAATGGTTGGCGCCGCCGCAACGTCAGT
GGCTGGTTAATAAAATGGCCGGTGAAATGGCGGAGACCGCTGGCGGACAATCACATCGCTGGAGCCAGGCGTTGACCAAC
CGGCGGGTTTGGGCGCTGAGCTTTATGTGGCTGTTGCAGGCGTTCGGCACCATAGGTATCACGCTATTTTTACCCTTGAT
CGTCAAGGGTGTAGTCACGGAGCAAAGCTCCTTTGTTGTCAATGTCCTTTCCGCCATTCCGTTTTTCTTTGCCTGCATTT
TCATGTACTTCAACGGTAGGCACTCCGATTTGACCGGTGAGCGATCCCTGCATTTGGGGGGGCCGCTGATTGCCGCCGGT
CTGCTGCTGCTGGCGGCGATTTATTGTCAAAATCTGGTGTTGGCCTACGGCATGTTGGTGCTTACCGTCGCGTTGAACTG
GGCGATCACCCCTATTTTCTGGGCGGTAACCACCGAATCTATCGCCGGCGTGGCTGGTGCGGCGTCAATAGCCTTGATTA
ATGCGGTGGCCAATATTGCCGGCCTGGTCTTTCCACCGGTCATGGGGCGAATTAAAGATATTACCGGCAACTATGATATT
GCGCTGATGGCCATCGCTGCGGCGTTGGTGGCTGGCGGCATTATCGGCCTGCGGCTTGGCAGGCCGCTATCAGCGGCCAC
AGGCGAGGTTGCACTGCGGGAGAACAACCATGGCTGA

Upstream 100 bases:

>100_bases
AACGAGTTTTTTCTGATGACGAGATGAAAACACCACTGGATGCGTGATTTGTCAGGAACAGATCGTGCAGAAATTAATGA
ATTGCTCTGGGGGATGAATT

Downstream 100 bases:

>100_bases
GACCATTTTGCAGGCCTCACCTTTGCCGCAAAGGTTGGTGGTGCAACTGCGTCAACATTTCCCATTGGTGGATCAGCGCG
AATTGGCCCCTTTGGCGCTG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MDSSTYSTTIKRMNRRIIPFIMLLYLIAYIDRSNISIAALQMNADLALSAEMYGIAAGIFYISYIIFEVPSNILLSRIGA
KIWIARIMVTWGIIAAGMSLVQTPTQLYVMRFLLGVAEAGFTPGIIYYLSCWYPRSDRARAMSMFYIGAALASVIGLPLS
GSILNMHGLFDIAGWRWLFLLEGIPAVLLGIVTYFYLDDAPQQAKWLAPPQRQWLVNKMAGEMAETAGGQSHRWSQALTN
RRVWALSFMWLLQAFGTIGITLFLPLIVKGVVTEQSSFVVNVLSAIPFFFACIFMYFNGRHSDLTGERSLHLGGPLIAAG
LLLLAAIYCQNLVLAYGMLVLTVALNWAITPIFWAVTTESIAGVAGAASIALINAVANIAGLVFPPVMGRIKDITGNYDI
ALMAIAAALVAGGIIGLRLGRPLSAATGEVALRENNHG

Sequences:

>Translated_438_residues
MDSSTYSTTIKRMNRRIIPFIMLLYLIAYIDRSNISIAALQMNADLALSAEMYGIAAGIFYISYIIFEVPSNILLSRIGA
KIWIARIMVTWGIIAAGMSLVQTPTQLYVMRFLLGVAEAGFTPGIIYYLSCWYPRSDRARAMSMFYIGAALASVIGLPLS
GSILNMHGLFDIAGWRWLFLLEGIPAVLLGIVTYFYLDDAPQQAKWLAPPQRQWLVNKMAGEMAETAGGQSHRWSQALTN
RRVWALSFMWLLQAFGTIGITLFLPLIVKGVVTEQSSFVVNVLSAIPFFFACIFMYFNGRHSDLTGERSLHLGGPLIAAG
LLLLAAIYCQNLVLAYGMLVLTVALNWAITPIFWAVTTESIAGVAGAASIALINAVANIAGLVFPPVMGRIKDITGNYDI
ALMAIAAALVAGGIIGLRLGRPLSAATGEVALRENNHG
>Mature_438_residues
MDSSTYSTTIKRMNRRIIPFIMLLYLIAYIDRSNISIAALQMNADLALSAEMYGIAAGIFYISYIIFEVPSNILLSRIGA
KIWIARIMVTWGIIAAGMSLVQTPTQLYVMRFLLGVAEAGFTPGIIYYLSCWYPRSDRARAMSMFYIGAALASVIGLPLS
GSILNMHGLFDIAGWRWLFLLEGIPAVLLGIVTYFYLDDAPQQAKWLAPPQRQWLVNKMAGEMAETAGGQSHRWSQALTN
RRVWALSFMWLLQAFGTIGITLFLPLIVKGVVTEQSSFVVNVLSAIPFFFACIFMYFNGRHSDLTGERSLHLGGPLIAAG
LLLLAAIYCQNLVLAYGMLVLTVALNWAITPIFWAVTTESIAGVAGAASIALINAVANIAGLVFPPVMGRIKDITGNYDI
ALMAIAAALVAGGIIGLRLGRPLSAATGEVALRENNHG

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=404, Percent_Identity=23.019801980198, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI87082071, Length=426, Percent_Identity=34.7417840375587, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI2367379, Length=431, Percent_Identity=25.0580046403712, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789152, Length=443, Percent_Identity=25.0564334085779, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI2367193, Length=244, Percent_Identity=23.3606557377049, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789515, Length=437, Percent_Identity=23.1121281464531, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082320, Length=422, Percent_Identity=21.0900473933649, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=295, Percent_Identity=24.406779661017, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6321698, Length=294, Percent_Identity=23.8095238095238, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319876, Length=248, Percent_Identity=24.5967741935484, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6322612, Length=243, Percent_Identity=22.2222222222222, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323032, Length=241, Percent_Identity=22.8215767634855, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324410, Length=164, Percent_Identity=26.219512195122, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321502, Length=311, Percent_Identity=24.7588424437299, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319250, Length=183, Percent_Identity=24.0437158469945, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583789, Length=214, Percent_Identity=24.2990654205607, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573708, Length=386, Percent_Identity=21.2435233160622, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573707, Length=386, Percent_Identity=21.2435233160622, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19922400, Length=425, Percent_Identity=22.1176470588235, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47674; Mature: 47674

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSSTYSTTIKRMNRRIIPFIMLLYLIAYIDRSNISIAALQMNADLALSAEMYGIAAGIF
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEHHHHHHHHHHHH
YISYIIFEVPSNILLSRIGAKIWIARIMVTWGIIAAGMSLVQTPTQLYVMRFLLGVAEAG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
FTPGIIYYLSCWYPRSDRARAMSMFYIGAALASVIGLPLSGSILNMHGLFDIAGWRWLFL
CCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHH
LEGIPAVLLGIVTYFYLDDAPQQAKWLAPPQRQWLVNKMAGEMAETAGGQSHRWSQALTN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
RRVWALSFMWLLQAFGTIGITLFLPLIVKGVVTEQSSFVVNVLSAIPFFFACIFMYFNGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
HSDLTGERSLHLGGPLIAAGLLLLAAIYCQNLVLAYGMLVLTVALNWAITPIFWAVTTES
CCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGVAGAASIALINAVANIAGLVFPPVMGRIKDITGNYDIALMAIAAALVAGGIIGLRLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHEECC
RPLSAATGEVALRENNHG
CCCCCCCCCEEEECCCCC
>Mature Secondary Structure
MDSSTYSTTIKRMNRRIIPFIMLLYLIAYIDRSNISIAALQMNADLALSAEMYGIAAGIF
CCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEHHHHHHHHHHHH
YISYIIFEVPSNILLSRIGAKIWIARIMVTWGIIAAGMSLVQTPTQLYVMRFLLGVAEAG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
FTPGIIYYLSCWYPRSDRARAMSMFYIGAALASVIGLPLSGSILNMHGLFDIAGWRWLFL
CCCCHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHH
LEGIPAVLLGIVTYFYLDDAPQQAKWLAPPQRQWLVNKMAGEMAETAGGQSHRWSQALTN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
RRVWALSFMWLLQAFGTIGITLFLPLIVKGVVTEQSSFVVNVLSAIPFFFACIFMYFNGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
HSDLTGERSLHLGGPLIAAGLLLLAAIYCQNLVLAYGMLVLTVALNWAITPIFWAVTTES
CCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAGVAGAASIALINAVANIAGLVFPPVMGRIKDITGNYDIALMAIAAALVAGGIIGLRLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHEECC
RPLSAATGEVALRENNHG
CCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]