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The map label for this gene is tdcD [H]

Identifier: 157162597

GI number: 157162597

Start: 3311290

End: 3312498

Strand: Reverse

Name: tdcD [H]

Synonym: EcHS_A3303

Alternate gene names: 157162597

Gene position: 3312498-3311290 (Counterclockwise)

Preceding gene: 157162598

Following gene: 157162596

Centisome position: 71.34

GC content: 48.3

Gene sequence:

>1209_bases
ATGAATGAATTTCCGGTTGTTTTGGTTATTAACTGTGGTTCGTCTTCGATTAAGTTTTCCGTGCTCGATGCCAGCGACTG
TGAAGTATTAATGTCAGGTATTGCCGACGGTATTAACTCGGAAAATGCATTCTTATCCGTAAATGGGGGAGAGCCAGCAC
CGCTGGCTCACCACAGCTACGAAGGTGCATTGAAGGCAATTGCATTTGAACTGGAAAAACGGAATTTAAATGACAGTGTG
GCCTTAATTGGCCACCGCATCGCTCACGGCGGCAGTATTTTTACCGAGTCCGCCATTATTACCGATGAAGTCATTGATAA
TATCCGTCGCGTTTCTCCACTGGCACCCCTGCATAATTACGCCAATTTAAGTGGTATTGAATCGGCGCAGCAATTATTTC
CGGGCGTAACTCAGGTGGCGGTATTTGATACCAGTTTCCACCAGACGATGGCTCCGGAAGCTTATTTATACGGCCTGCCG
TGGAAATATTATGAAGAGTTAGGTGTACGCCGTTATGGTTTCCACGGCACGTCGCACCGCTATGTTTCCCAGCGCGCACA
TTCGCTGCTGAATCTGGCGGAAGATGACTCCGGCCTGGTTGTGGCGCATCTTGGCAATGGCGCGTCAATCTGCGCGGTTC
GCAACGGTCAGAGTGTTGATACCTCAATGGGAATGACGCCGCTGGAAGGCTTGATGATGGGTACCCGCAGTGGCGATGTC
GACTTTGGTGCGATGTCCTGGGTCGCCAGCCAAACCAACCAGAGCCTGGGTGACCTGGAACGCGTAGTGAATAAAGAGTC
GGGATTATTAGGTATTTCCGGTCTTTCTTCGGATTTACGTGTTCTGGAAAAAGCCTGGCATGAAGGTCACGAACGCGCGC
AACTGGCAATTAAAACCTTTGTTCACCGAATTGCCCGTCATATTGCCGGACACGCAGCTTCATTACGTCGCCTGGATGGA
ATTATATTCACCGGCGGAATAGGAGAGAATTCAAGCTTAATTCGTCGTCTGGTCATGGAACATTTGGCTGTATTAGGCTT
AGAGATTGATACAGAAATGAATAATCGCTCTAACTCCTGTGGTGAGCGAATTGTTTCCAGTGAAAATGCGCGTGTCATTT
GTGCCGTTATTCCGACTAACGAAGAAAAAATGATTGCTTTGGATGCCATTCATTTAGGCAAAGTTAACGCGCCCGCAGAA
TTTGCATAA

Upstream 100 bases:

>100_bases
GGTCGTCTGGATAACGTGTTTGTTACCGTGATTGGTCTGCTGACCATCCTGAACATCGTATACAAACTGTTTTAATCCGT
AACTCAGGATGAGAAAAGAG

Downstream 100 bases:

>100_bases
TTTAGTTGAAGTATTGTAGAGAGATTATTTTTCATGAAGGTAGATATTGATACCAGCGATAAGCTGTACGCCGACGCATG
GCTTGGCTTTAAAGGTACGG

Product: propionate/acetate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSV
ALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLP
WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDV
DFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDG
IIFTGGIGENSSLIRRLVMEHLAVLGLEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAE
FA

Sequences:

>Translated_402_residues
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSV
ALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLP
WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDV
DFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDG
IIFTGGIGENSSLIRRLVMEHLAVLGLEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAE
FA
>Mature_402_residues
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSV
ALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLP
WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDV
DFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDG
IIFTGGIGENSSLIRRLVMEHLAVLGLEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAE
FA

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family. TdcD subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693184, Length=402, Percent_Identity=100, Blast_Score=822, Evalue=0.0,
Organism=Escherichia coli, GI1788633, Length=396, Percent_Identity=43.9393939393939, Blast_Score=315, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.15 [H]

Molecular weight: Translated: 43385; Mature: 43385

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS01075 ACETATE_KINASE_1 ; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSY
CCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCH
EGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHH
ANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHR
CCCCHHHHHHHHCCCCEEEEEEECHHHHHCCCCCEEECCCHHHHHHCCCEEECCCCCCHH
YVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDV
HHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCHHHHHEECCCCCCC
DFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTF
CCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHH
VHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGLEIDTEMNNRSNSC
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCHH
GERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
HHHHHCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSY
CCCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCH
EGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNY
HHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHH
ANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHR
CCCCHHHHHHHHCCCCEEEEEEECHHHHHCCCCCEEECCCHHHHHHCCCEEECCCCCCHH
YVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDV
HHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCHHHHHEECCCCCCC
DFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTF
CCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHH
VHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGLEIDTEMNNRSNSC
HHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCEEEECCCCCCCCHH
GERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
HHHHHCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA