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The map label for this gene is yehC

Identifier: 157161594

GI number: 157161594

Start: 2233275

End: 2233949

Strand: Reverse

Name: yehC

Synonym: EcHS_A2246

Alternate gene names: 157161594

Gene position: 2233949-2233275 (Counterclockwise)

Preceding gene: 157161595

Following gene: 157161593

Centisome position: 48.11

GC content: 38.96

Gene sequence:

>675_bases
ATGAAAGGATTATTATCTTTACTCATTTTTTCTATGGTCCTTCCTGCACATGCCGGAATTGTTATCTACGGGACGCGCAT
TATTTACCCGGCAGAAAATAAAGAAGTGATGGTGCAGTTGATGAACCAGGGAAACCGTTCTTCGCTGCTGCAGGCGTGGA
TTGATGATGGCGATACGTCATTACCACCAGAAAAAATTCAGGTTCCTTTCATGTTAACGCCACCAGTGGCAAAAATAGGG
GCAAATTCCGGGCAGCAAGTAAAAATCAAAATTATGCCGAATAAACTGCCCACTAATAAAGAAAGCATTTTTTATCTGAA
TGTTCTGGATATTCCACCAAATAGTCCAGAGCAAGAAGGTAAGAATGCACTGAAGTTTGCGATGCAAAACAGAATTAAGT
TGTTTTACCGGCCAGCGGGTATTGCTCCGGTAAATAAAGCGACATTTAAAAAATTGCTGGTAAATCGCAGTGGCAATGGT
TTGGTGATAAAAAATGACTCAGCTAATTGGGTGACGATTTCGGATGTCAAAGCTAATAATGTCAAAGTCAATTATGAAAC
TATTATGATTGCCCCCTTAGAAAGTCAGAGTGTTAATGTCAAAAGTAATAATGCAAATAACTGGCATCTGACCATTATCG
ATGACCATGGCAACTATATTAGTGACAAAATTTAA

Upstream 100 bases:

>100_bases
ATGCGTGTGGCGCAGGATTAATAAATAAAATTGTAAGTTTCTCCAGGTAATAAACATGGCCGCTATCCCATGGCGGCCTT
TTAATTTAAGAGGCATTAAA

Downstream 100 bases:

>100_bases
TTGCAGGAGCTGCCTATGTTGAGAATGACCCCACTTGCATCAGTAATCGTAGCGTTATTGCTCGGCATTGAAGCTTATGC
AGCTGAAGAAACCTTTGATA

Product: pilus assembly chaperone

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKGLLSLLIFSMVLPAHAGIVIYGTRIIYPAENKEVMVQLMNQGNRSSLLQAWIDDGDTSLPPEKIQVPFMLTPPVAKIG
ANSGQQVKIKIMPNKLPTNKESIFYLNVLDIPPNSPEQEGKNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNG
LVIKNDSANWVTISDVKANNVKVNYETIMIAPLESQSVNVKSNNANNWHLTIIDDHGNYISDKI

Sequences:

>Translated_224_residues
MKGLLSLLIFSMVLPAHAGIVIYGTRIIYPAENKEVMVQLMNQGNRSSLLQAWIDDGDTSLPPEKIQVPFMLTPPVAKIG
ANSGQQVKIKIMPNKLPTNKESIFYLNVLDIPPNSPEQEGKNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNG
LVIKNDSANWVTISDVKANNVKVNYETIMIAPLESQSVNVKSNNANNWHLTIIDDHGNYISDKI
>Mature_224_residues
MKGLLSLLIFSMVLPAHAGIVIYGTRIIYPAENKEVMVQLMNQGNRSSLLQAWIDDGDTSLPPEKIQVPFMLTPPVAKIG
ANSGQQVKIKIMPNKLPTNKESIFYLNVLDIPPNSPEQEGKNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNG
LVIKNDSANWVTISDVKANNVKVNYETIMIAPLESQSVNVKSNNANNWHLTIIDDHGNYISDKI

Specific function: Could be required for the biogenesis of a putative fimbria

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain

Homologues:

Organism=Escherichia coli, GI1788428, Length=224, Percent_Identity=100, Blast_Score=452, Evalue=1e-128,
Organism=Escherichia coli, GI1786333, Length=221, Percent_Identity=37.10407239819, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789532, Length=217, Percent_Identity=31.3364055299539, Blast_Score=107, Evalue=4e-25,
Organism=Escherichia coli, GI1786936, Length=222, Percent_Identity=29.7297297297297, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790771, Length=219, Percent_Identity=28.310502283105, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788677, Length=201, Percent_Identity=34.8258706467662, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786743, Length=221, Percent_Identity=29.8642533936652, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1787171, Length=227, Percent_Identity=25.5506607929515, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI87082203, Length=222, Percent_Identity=27.4774774774775, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI87081806, Length=229, Percent_Identity=24.8908296943231, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YEHC_ECOLI (P33342)

Other databases:

- EMBL:   U00007
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   E64978
- RefSeq:   AP_002708.1
- RefSeq:   NP_416613.1
- ProteinModelPortal:   P33342
- SMR:   P33342
- STRING:   P33342
- EnsemblBacteria:   EBESCT00000000969
- EnsemblBacteria:   EBESCT00000016396
- GeneID:   946621
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2097
- KEGG:   eco:b2110
- EchoBASE:   EB1932
- EcoGene:   EG11989
- eggNOG:   COG3121
- GeneTree:   EBGT00070000031707
- HOGENOM:   HBG758617
- OMA:   WITIPEI
- ProtClustDB:   CLSK879542
- BioCyc:   EcoCyc:EG11989-MONOMER
- Genevestigator:   P33342
- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147
- Gene3D:   G3DSA:2.60.40.360
- Gene3D:   G3DSA:2.60.40.1070
- PRINTS:   PR00969

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N; SSF49354 PapD-like; SSF49584 Pili_assmbl_chaperone_C_bac

EC number: NA

Molecular weight: Translated: 24837; Mature: 24837

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLLSLLIFSMVLPAHAGIVIYGTRIIYPAENKEVMVQLMNQGNRSSLLQAWIDDGDTS
CHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHCCCCCC
LPPEKIQVPFMLTPPVAKIGANSGQQVKIKIMPNKLPTNKESIFYLNVLDIPPNSPEQEG
CCHHHEEEEEEECCCHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCCHHHH
KNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNGLVIKNDSANWVTISDVKANN
HHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCC
VKVNYETIMIAPLESQSVNVKSNNANNWHLTIIDDHGNYISDKI
EEEEEEEEEEEECCCCEEEEECCCCCEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKGLLSLLIFSMVLPAHAGIVIYGTRIIYPAENKEVMVQLMNQGNRSSLLQAWIDDGDTS
CHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHCCCCCC
LPPEKIQVPFMLTPPVAKIGANSGQQVKIKIMPNKLPTNKESIFYLNVLDIPPNSPEQEG
CCHHHEEEEEEECCCHHHHCCCCCCEEEEEEECCCCCCCCCEEEEEEEEECCCCCCHHHH
KNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNGLVIKNDSANWVTISDVKANN
HHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCC
VKVNYETIMIAPLESQSVNVKSNNANNWHLTIIDDHGNYISDKI
EEEEEEEEEEEECCCCEEEEECCCCCEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503