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The map label for this gene is wzb [C]

Identifier: 157161546

GI number: 157161546

Start: 2174782

End: 2175219

Strand: Reverse

Name: wzb [C]

Synonym: EcHS_A2192

Alternate gene names: 157161546

Gene position: 2175219-2174782 (Counterclockwise)

Preceding gene: 157161547

Following gene: 157161545

Centisome position: 46.84

GC content: 41.1

Gene sequence:

>438_bases
ATGTTTGAATCAATTTTAGTTATTTGTACGGGCAATATTTGTCGTTCTCCAATAGGAGAACGGCTTTTACGAAAATTGCT
TCCCTCAAAGGTGATTAATTCGGCTGGTACGAATGCAATGGTTGGTTATAGCGCCGATTTGAATGCTTGTAAAATCGCAT
CATTGCATAATCTTTCGCTCGAAAATCATGTAGCAAAACAATACTCAGCGTCCATGGGGCGCAAGTACGATCTTATATTA
GTAATGGAAAAGGCCCATATAGAGCAAATCGGGCGTATCTCACCCGAAGCCAGAGGGAAAACAATGCTTTATGGTCACTG
GTGCAACCAGCGAGATATCCCAGATCCATATAGGAAAAGTGAAGAAGCATTTGCATCAGTATATAATTTAATAGAATTGG
CCGGTGAGCGGTGGGCTGAAAAACTAGGCGCAAAATAA

Upstream 100 bases:

>100_bases
TTAGTACGTTGGAATCGTGTAATTTCCCAACTTGTACCTACCATTACTGGAGTACATGATATGACAGAAACTGTAAGATA
TATTAGGACCTGGCCATAAA

Downstream 100 bases:

>100_bases
TCAGGAATATTTTAATGTCACCAGTTATTAATAAACAAGCATCTCAGGAATCTGATGAAATCGATTTTGGTCGCTTAATC
GGTGAATTGATTGATCATCG

Product: low molecular weight phosphotyrosine protein phosphatase

Products: NA

Alternate protein names: ORF5 [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MFESILVICTGNICRSPIGERLLRKLLPSKVINSAGTNAMVGYSADLNACKIASLHNLSLENHVAKQYSASMGRKYDLIL
VMEKAHIEQIGRISPEARGKTMLYGHWCNQRDIPDPYRKSEEAFASVYNLIELAGERWAEKLGAK

Sequences:

>Translated_145_residues
MFESILVICTGNICRSPIGERLLRKLLPSKVINSAGTNAMVGYSADLNACKIASLHNLSLENHVAKQYSASMGRKYDLIL
VMEKAHIEQIGRISPEARGKTMLYGHWCNQRDIPDPYRKSEEAFASVYNLIELAGERWAEKLGAK
>Mature_145_residues
MFESILVICTGNICRSPIGERLLRKLLPSKVINSAGTNAMVGYSADLNACKIASLHNLSLENHVAKQYSASMGRKYDLIL
VMEKAHIEQIGRISPEARGKTMLYGHWCNQRDIPDPYRKSEEAFASVYNLIELAGERWAEKLGAK

Specific function: Dephosphorylates Wzc. Required For The Extracellular Polysaccharide Colanic Acid Synthesis. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788375, Length=145, Percent_Identity=54.4827586206897, Blast_Score=171, Evalue=2e-44,
Organism=Escherichia coli, GI87081812, Length=141, Percent_Identity=56.0283687943262, Blast_Score=167, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16196; Mature: 16196

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESILVICTGNICRSPIGERLLRKLLPSKVINSAGTNAMVGYSADLNACKIASLHNLSL
CCCCEEEEEECCHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCH
ENHVAKQYSASMGRKYDLILVMEKAHIEQIGRISPEARGKTMLYGHWCNQRDIPDPYRKS
HHHHHHHHHHHCCCCEEEEEEECHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHH
EEAFASVYNLIELAGERWAEKLGAK
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFESILVICTGNICRSPIGERLLRKLLPSKVINSAGTNAMVGYSADLNACKIASLHNLSL
CCCCEEEEEECCHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHCCCH
ENHVAKQYSASMGRKYDLILVMEKAHIEQIGRISPEARGKTMLYGHWCNQRDIPDPYRKS
HHHHHHHHHHHCCCCEEEEEEECHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHH
EEAFASVYNLIELAGERWAEKLGAK
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7896702 [H]