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The map label for this gene is yebQ

Identifier: 157161295

GI number: 157161295

Start: 1929253

End: 1930626

Strand: Direct

Name: yebQ

Synonym: EcHS_A1919

Alternate gene names: 157161295

Gene position: 1929253-1930626 (Clockwise)

Preceding gene: 157161293

Following gene: 157161300

Centisome position: 41.55

GC content: 52.33

Gene sequence:

>1374_bases
ATGCCAAAAGTTCAGGCCGACGGCCTGCCATTGCCCCAGCGATACGGTGCGATATTAACCATTGTGATTGGTATTTCGAT
GGCTGTCCTTGACGGCGCAATCGCCAACGTCGCCCTGCCAACAATCGCCACGGACCTTCATGCCACGCCAGCCAGTTCCA
TCTGGGTAGTGAACGCCTATCAAATCGCCATTGTCATCTCCCTGCTCTCGTTTTCGTTTCTGGGCGATATGTTTGGCTAT
CGACGTATTTATAAATGCGGTCTGGTCGTTTTTCTGTTGTCTTCACTGTTCTGCGCCCTTTCTGATTCGCTGCAAATGCT
CACCCTTGCGCGTGTCATACAAGGTTTCGGCGGTGCAGCGTTGATGAGCGTTAATACCGCACTTATCCGCCTGATCTATC
CACAACGTTTTCTGGGGAGAGGGATGGGCATAAACTCGTTTATTGTTGCCGTCTCTTCTGCTGCCGGGCCGACAATTGCT
GCAGCAATCCTCTCCATCGCATCCTGGAAATGGTTATTTTTAATCAACGTACCGTTAGGTATTATCGCCCTGCTTCTGGC
GATGCGTTTTCTGCCACCCAATGGTTCTCGCGCCAGTAAACCCCGTTTCGACCTGCCCAGCGCCGTGATGAACGCGTTAA
CCTTCGGCCTGCTTATCACTGCGTTGAGTGGTTTCGCTCAGGGGCAATCGCTAACGTTAATTGCTGCGGAACTGGTGGTA
ATGGTTGTTGTTGGTATTTTCTTTATTCGCCGCCAGCTTTCTCTTCCCGTACCGCTGCTACCGGTGGATTTACTGCGTAT
CCCGCTGTTTTCACTTTCTATTTGCACATCTGTTTGCTCTTTCTGCGCACAAATGCTGGCAATGGTTTCCCTGCCCTTTT
ACCTGCAAACCGTGCTCGGGCGTAGTGAAGTCGAAACAGGTTTACTTCTGACACCGTGGCCGTTAGCAACGATGGTGATG
GCTCCGCTGGCAGGCTATTTGATTGAACGCGTACATGCAGGATTGCTGGGTGCTTTAGGGTTGTTCATCATGGCTGCGGG
GCTTTTTTCCCTGGTTCTGCTGCCCGCGTCACCTGCGGATATCAATATTATCTGGCCGATGATCTTATGTGGCGCTGGAT
TTGGCTTATTCCAGTCACCCAATAACCACACCATTATTACCTCCGCTCCGCGCGAACGTAGCGGTGGGGCCAGTGGCATG
TTAGGAACGGCTCGTCTACTGGGTCAGAGTAGTGGCGCGGCGCTGGTGGCGCTGATGCTAAATCAGTTCGGTGATAATGG
TACGCACGTTTCGCTGATGGCTGCGGCTATTCTGGCAGTGATTGCTGCCTGTGTGAGTGGTTTACGTATCACTCAGCCAC
GATCCAGGGCATAA

Upstream 100 bases:

>100_bases
CCATCTTTTGCCGGTTAGTTACAATTCTGCGACATCCACCGTGAATATCAGTGCTAGAATCATACCCCTGTTGATTATTC
ACCAAAGATATAAAATTCCT

Downstream 100 bases:

>100_bases
AAAAAGCGCGTCGATCAGGACGCGCTTTTTAGTATTTACTTCATATTACTTCAGGTATTCACCCGTACGCAGAGCTTCAA
TTCGTTTATCCAGCGGCGGG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MPKVQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGY
RRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIA
AAILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVV
MVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVM
APLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGM
LGTARLLGQSSGAALVALMLNQFGDNGTHVSLMAAAILAVIAACVSGLRITQPRSRA

Sequences:

>Translated_457_residues
MPKVQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGY
RRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIA
AAILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVV
MVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVM
APLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGM
LGTARLLGQSSGAALVALMLNQFGDNGTHVSLMAAAILAVIAACVSGLRITQPRSRA
>Mature_456_residues
PKVQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGYR
RIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAA
AILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVM
VVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMA
PLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGML
GTARLLGQSSGAALVALMLNQFGDNGTHVSLMAAAILAVIAACVSGLRITQPRSRA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family

Homologues:

Organism=Escherichia coli, GI87081983, Length=457, Percent_Identity=100, Blast_Score=893, Evalue=0.0,
Organism=Escherichia coli, GI1790195, Length=437, Percent_Identity=27.9176201372998, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789042, Length=425, Percent_Identity=27.2941176470588, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1788392, Length=429, Percent_Identity=29.1375291375291, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788710, Length=440, Percent_Identity=26.3636363636364, Blast_Score=114, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6325455, Length=167, Percent_Identity=28.1437125748503, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YEBQ_ECOLI (P76269)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_002448.1
- RefSeq:   NP_416342.4
- ProteinModelPortal:   P76269
- STRING:   P76269
- EnsemblBacteria:   EBESCT00000000860
- EnsemblBacteria:   EBESCT00000015845
- GeneID:   946048
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5299
- KEGG:   eco:b1828
- EchoBASE:   EB3773
- EcoGene:   EG14019
- eggNOG:   COG0477
- GeneTree:   EBGT00050000008825
- HOGENOM:   HBG679341
- OMA:   ICTSICS
- ProtClustDB:   CLSK880224
- BioCyc:   EcoCyc:B1828-MONOMER
- Genevestigator:   P76269
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411
- PRINTS:   PR01036

Pfam domain/function: PF07690 MFS_1; SSF103473 MFS_gen_substrate_transporter

EC number: NA

Molecular weight: Translated: 48152; Mature: 48021

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x14f4fa08)-; HASH(0x1480d3d0)-; HASH(0x14de39a8)-; HASH(0x15204398)-; HASH(0x11abd7f0)-; HASH(0x14ccda90)-; HASH(0x11a71574)-; HASH(0x1413ffa0)-; HASH(0x14e1fa78)-; HASH(0x14ce0e40)-; HASH(0x148b31a4)-; HASH(0x14d1f988)-; HASH(0x155599c0)-; HASH(0x15163c68)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHH
QIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCCCHHHHHHHHHHHCCCEEEEEECCHH
IIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVV
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RSEVETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPAD
HHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
INIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVALML
CCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHH
NQFGDNGTHVSLMAAAILAVIAACVSGLRITQPRSRA
HHHCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCH
>Mature Secondary Structure 
PKVQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAY
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHH
QIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCCCHHHHHHHHHHHCCCEEEEEECCHH
IIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVV
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
MVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RSEVETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPAD
HHHHCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
INIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVALML
CCHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHH
NQFGDNGTHVSLMAAAILAVIAACVSGLRITQPRSRA
HHHCCCCCHHHHHHHHHHHHHHHHHCCCEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503