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The map label for this gene is proQ

Identifier: 157159080

GI number: 157159080

Start: 2042433

End: 2043131

Strand: Reverse

Name: proQ

Synonym: EcE24377A_2060

Alternate gene names: 157159080

Gene position: 2043131-2042433 (Counterclockwise)

Preceding gene: 157158805

Following gene: 157155122

Centisome position: 41.03

GC content: 53.22

Gene sequence:

>699_bases
ATGGAAAATCAACCTAAGTTGAATAGCAGTAAAGAAGTAATCGCGTTTCTGGCCGAACGTTTTCCCCACTGTTTCAGTGC
GGAAGGTGAAGCGCGTCCGCTGAAAATCGGTATTTTTCAGGATTTGGTCGATCGTGTTGCCGGGGAAATGAACCTGAGCA
AAACGCAATTACGATCCGCTTTACGTCTCTACACTTCGAGCTGGCGTTATCTTTACGGTGTTAAACCCGGCGCAACGCGT
GTCGATCTTGACGGCAACCCATGCGGTGAGCTGGACGAGCAACATGTAGAGCATGCTCGCAAGCAGCTTGAAGAAGCGAA
AGCGCGTGTTCAGGCACAGCGTGCTGAACAGCAAGCGAAAAAACGCGAAGCTGCCGCAGCTGCTGGTGAGAAAGAAGACG
CACCGCCCCGCGAACGCAAGCCACGTCCGACCACGCCACGCCGCAAAGAAGGCGCTGAACGTAAACCTCGTGCGCAAAAG
CCGGTAGAGAAAGCGCCAAAAACAGTAAAAGCACCTCGCGAAGAACAGCACACCCCGGTTTCTGACATTTCAGCTCTGAC
TGTCGGACAAGCCCTGAAGGTGAAAGCGGGTCAAAACGCGATGGATGCCACCGTATTAGAAATCACCAAAGACGGCGTCC
GCGTCCAGCTGAATTCGGGTATGTCTTTGATTGTGCGCGCAGAACACCTGGTGTTCTGA

Upstream 100 bases:

>100_bases
ATAATCAACGGATAACGTAGCATTTACTGGTAGCGTCATTATAATGACGCCTGTTCATGCCTGCGCTTGTTGGCTACGTC
CGTTGTAATCAGGAAATTTC

Downstream 100 bases:

>100_bases
AACGGAGGCCGGGCCAGGCATGAACATGTTTTTTAGGCTTACCGCGTTAGCTGGCCTGCTTGCAATAGCAGGCCAGACCT
TCGCTGTAGAAGATATCACG

Product: putative solute/DNA competence effector

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATR
VDLDGNPCGELDEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPPRERKPRPTTPRRKEGAERKPRAQK
PVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF

Sequences:

>Translated_232_residues
MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATR
VDLDGNPCGELDEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPPRERKPRPTTPRRKEGAERKPRAQK
PVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
>Mature_232_residues
MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATR
VDLDGNPCGELDEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPPRERKPRPTTPRRKEGAERKPRAQK
PVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF

Specific function: Not exactly known; may be a structural element that influences the osmotic activation of proP at a post-translational level

COG id: COG3109

COG function: function code T; Activator of osmoprotectant transporter ProP

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proQ family

Homologues:

Organism=Escherichia coli, GI48994892, Length=232, Percent_Identity=99.1379310344828, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PROQ_ECO24 (A7ZMV4)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001463133.1
- ProteinModelPortal:   A7ZMV4
- SMR:   A7ZMV4
- STRING:   A7ZMV4
- EnsemblBacteria:   EBESCT00000019889
- GeneID:   5586643
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_2060
- NMPDR:   fig|331111.3.peg.4479
- eggNOG:   COG3109
- GeneTree:   EBGT00050000009427
- HOGENOM:   HBG495470
- OMA:   RFPQCFS
- ProtClustDB:   PRK04950
- BioCyc:   ECOL331111:ECE24377A_2060-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00749
- InterPro:   IPR016103
- Gene3D:   G3DSA:1.10.1710.10
- SMART:   SM00945

Pfam domain/function: PF04352 ProQ; SSF48657 FINO

EC number: NA

Molecular weight: Translated: 25804; Mature: 25804

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSA
CCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHH
LRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQLEEAKARVQAQRAEQQAK
HHHHHCCCCEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KREAAAAAGEKEDAPPRERKPRPTTPRRKEGAERKPRAQKPVEKAPKTVKAPREEQHTPV
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHCCHHHCCCCHHCCCCH
SDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
HHHHHHHHCHHHEECCCCCHHHHHHHEEECCCEEEEECCCCEEEEEHHHHCC
>Mature Secondary Structure
MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSA
CCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHH
LRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQLEEAKARVQAQRAEQQAK
HHHHHCCCCEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KREAAAAAGEKEDAPPRERKPRPTTPRRKEGAERKPRAQKPVEKAPKTVKAPREEQHTPV
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCHHHCCHHHCCCCHHCCCCH
SDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
HHHHHHHHCHHHEECCCCCHHHHHHHEEECCCEEEEECCCCEEEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA