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The map label for this gene is spaP [H]

Identifier: 157159039

GI number: 157159039

Start: 3199048

End: 3199713

Strand: Reverse

Name: spaP [H]

Synonym: EcE24377A_3184

Alternate gene names: 157159039

Gene position: 3199713-3199048 (Counterclockwise)

Preceding gene: 157154771

Following gene: 157158179

Centisome position: 64.26

GC content: 34.23

Gene sequence:

>666_bases
ATGTCAAATAGCATTTCGCTGATAGCGATATTATCATTATTTACACTATTGCCGTTTATAATAGCATCCGGGACATGTTT
TATTAAATTCTCGATTGTTTTTGTTATTGTCCGAAAAGCGCTGGGACTTCAGCAAGTGCCATCAAATATGACACTTAATG
GGGTTGCTTTGCTATTGTCAATGTTCGTAATGATGCCGGTTGGGAAGGAAATATATAATAACAGTCAGAATGAGAATCTT
TCATTCAATAATGTAGCATCAGTTGTTAATTTTGTTGAGACAGGCATGAGTGGTTATAAATCATATTTGATAAAATATTC
TGAACCTGAGTTGGTTAGCTTTTTTGAAAAGATTCAGAAGGTGAATAGTTCTGAAGACAATGAAGAGATAATCGATGATG
ATAATATTTCAATTTTCTCGTTACTGCCCGCATATGCATTGAGTGAGATAAAAAGTGCATTTATTATAGGTTTTTATATC
TATTTACCCTTTGTCGTAGTGGATCTGGTTATATCCAGCGTTCTGTTAACGTTAGGTATGATGATGATGAGTCCGGTAAC
CATATCTACACCGATAAAATTAATTTTGTTTGTCGCGATGGACGGTTGGACAATGTTATCAAAAGGGCTAATTTTACAAT
ATTTTGACCTATCCATTAATCCCTGA

Upstream 100 bases:

>100_bases
AAAATACGTGTAAATGGCGCGCTAACTGGCTATGGCGAACTTGTTGAAGTGGATGATAAATTGGGCGTAGAAATTCATTC
TTGGTTATCAGGGAATAATA

Downstream 100 bases:

>100_bases
GGAAAAAATATGGACGATATTGTTTTTGCGGGGAATAGGGCGCTGTATCTGATTTTAGTTATGTCTGCAGGACCTATTGC
AGTTGCGACATTTGTTGGTT

Product: surface presentation of antigens protein SpaP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MSNSISLIAILSLFTLLPFIIASGTCFIKFSIVFVIVRKALGLQQVPSNMTLNGVALLLSMFVMMPVGKEIYNNSQNENL
SFNNVASVVNFVETGMSGYKSYLIKYSEPELVSFFEKIQKVNSSEDNEEIIDDDNISIFSLLPAYALSEIKSAFIIGFYI
YLPFVVVDLVISSVLLTLGMMMMSPVTISTPIKLILFVAMDGWTMLSKGLILQYFDLSINP

Sequences:

>Translated_221_residues
MSNSISLIAILSLFTLLPFIIASGTCFIKFSIVFVIVRKALGLQQVPSNMTLNGVALLLSMFVMMPVGKEIYNNSQNENL
SFNNVASVVNFVETGMSGYKSYLIKYSEPELVSFFEKIQKVNSSEDNEEIIDDDNISIFSLLPAYALSEIKSAFIIGFYI
YLPFVVVDLVISSVLLTLGMMMMSPVTISTPIKLILFVAMDGWTMLSKGLILQYFDLSINP
>Mature_220_residues
SNSISLIAILSLFTLLPFIIASGTCFIKFSIVFVIVRKALGLQQVPSNMTLNGVALLLSMFVMMPVGKEIYNNSQNENLS
FNNVASVVNFVETGMSGYKSYLIKYSEPELVSFFEKIQKVNSSEDNEEIIDDDNISIFSLLPAYALSEIKSAFIIGFYIY
LPFVVVDLVISSVLLTLGMMMMSPVTISTPIKLILFVAMDGWTMLSKGLILQYFDLSINP

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells [H]

COG id: COG4790

COG function: function code U; Type III secretory pathway, component EscR

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliP/mopC/spaP family [H]

Homologues:

Organism=Escherichia coli, GI1788259, Length=215, Percent_Identity=35.8139534883721, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005838
- InterPro:   IPR005773 [H]

Pfam domain/function: PF00813 FliP [H]

EC number: NA

Molecular weight: Translated: 24539; Mature: 24408

Theoretical pI: Translated: 4.30; Mature: 4.30

Prosite motif: PS01061 FLIP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSISLIAILSLFTLLPFIIASGTCFIKFSIVFVIVRKALGLQQVPSNMTLNGVALLLS
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHH
MFVMMPVGKEIYNNSQNENLSFNNVASVVNFVETGMSGYKSYLIKYSEPELVSFFEKIQK
HHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VNSSEDNEEIIDDDNISIFSLLPAYALSEIKSAFIIGFYIYLPFVVVDLVISSVLLTLGM
HCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMMSPVTISTPIKLILFVAMDGWTMLSKGLILQYFDLSINP
HHHCCCCCCCHHHHHHHHHHCCHHHHHHCHHHHHCCCCCCC
>Mature Secondary Structure 
SNSISLIAILSLFTLLPFIIASGTCFIKFSIVFVIVRKALGLQQVPSNMTLNGVALLLS
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHH
MFVMMPVGKEIYNNSQNENLSFNNVASVVNFVETGMSGYKSYLIKYSEPELVSFFEKIQK
HHHHHCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
VNSSEDNEEIIDDDNISIFSLLPAYALSEIKSAFIIGFYIYLPFVVVDLVISSVLLTLGM
HCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MMMSPVTISTPIKLILFVAMDGWTMLSKGLILQYFDLSINP
HHHCCCCCCCHHHHHHHHHHCCHHHHHHCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7638176; 11677608; 12644504 [H]