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The map label for this gene is lsrR

Identifier: 157159022

GI number: 157159022

Start: 1716462

End: 1717415

Strand: Reverse

Name: lsrR

Synonym: EcE24377A_1713

Alternate gene names: 157159022

Gene position: 1717415-1716462 (Counterclockwise)

Preceding gene: 157155758

Following gene: 157154927

Centisome position: 34.49

GC content: 51.26

Gene sequence:

>954_bases
ATGACAATCAACGATTCGGCAATTTCAGAACAGGGAATGTGTGAAGAAGAACAGGTCGCGCGGATCGCGTGGTTTTACTA
TCACGACGGGCTGACCCAGAGCGAGATCAGCGATCGTCTCGGCCTGACCCGTTTGAAAGTGTCGCGCTTGCTGGAGAAAG
GGCATCAGTCCGGCATTATTCGCGTACAGATTAATTCTCGCTTTGAAGGCTGTCTGGAATATGAAACTCAATTACGTCGT
CAGTTTTCGCTGCAACATGTCCGGGTGATCCCTGGGCTTGCGGATGCTGATGTCGGCGGGCGACTGGGGATAGGCGCGGC
GCATATGTTGATGAGTTTACTTCAACCACAACAGATGCTGGCGATTGGTTTTGGCGAGGCAACCATGAATACGCTGCAAC
GCTTAAGTGGTTTTATTTCGTCACAGCAAATTCGCCTGGTCACGCTCTCCGGTGGCGTCGGTTCTTATATGACGGGTATC
GGGCAGCTTAACGCGGCGTGCAGTGTGAATATTATTCCGGCTCCGTTGCGGGCATCCTCCGCTGACATTGCCCGTACGCT
AAAAAATGAAAATTGCGTCAAAGATGTTCTGTTAGCCGCGCAAGCAGCCGATGTGGCGATTGTCGGCATTGGGGCCGTCA
GTCAACAGGACGACGCGACGATCATTCGCTCCGGTTATATCAGCCAGGGCGAACAGTTAATGATTGGTCGAAAAGGGGCG
GTTGGCGACATTTTAGGCTACTTTTTTGATGCAAAAGGTGACGTTGTCACGGATATTAAAATACATAACGAACTGATTGG
CTTACCTTTAAGCTCGCTGAAGACCATACCCGTCCGGGTTGGCGTGGCAGGGGGAGAAAATAAAGCCGAAGCAATTGCCG
CTGCAATGAAAGGCGGTTATATCAACGCACTGGTTACCGATCAGGACACAGCAGCGGCGATTTTACGTAGTTAA

Upstream 100 bases:

>100_bases
GCTCGTAGAGTCAAACTGTGGCTGCCATCACAGATATAAATGCGCAAGAACTGAACAATTGCATTAAAGATTTAAATATG
TTCAAAGTGAAGAATGAATT

Downstream 100 bases:

>100_bases
ATTTGCATGACCTTATTACCGGGAATGATGGAGAACGTATAGAGGAACAGACAGAACGCATAAGCCGAGGATAATCTAAT
GGCTCGACTCTTTACCCCTT

Product: transcriptional repressor LsrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MTINDSAISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRR
QFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGI
GQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGA
VGDILGYFFDAKGDVVTDIKIHNELIGLPLSSLKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS

Sequences:

>Translated_317_residues
MTINDSAISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRR
QFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGI
GQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGA
VGDILGYFFDAKGDVVTDIKIHNELIGLPLSSLKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS
>Mature_316_residues
TINDSAISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQ
FSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIG
QLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGAV
GDILGYFFDAKGDVVTDIKIHNELIGLPLSSLKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsr operon and its own transcription. In the presence of AI-2, lsrR is inactivated by binding phospho-AI-2, leading to the transcriptio

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family

Homologues:

Organism=Escherichia coli, GI1787791, Length=317, Percent_Identity=99.3690851735016, Blast_Score=638, Evalue=0.0,
Organism=Escherichia coli, GI87082414, Length=335, Percent_Identity=25.3731343283582, Blast_Score=101, Evalue=7e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): LSRR_ECO24 (A7ZLX0)

Other databases:

- EMBL:   CP000800
- RefSeq:   YP_001462799.1
- ProteinModelPortal:   A7ZLX0
- SMR:   A7ZLX0
- STRING:   A7ZLX0
- EnsemblBacteria:   EBESCT00000019022
- GeneID:   5588050
- GenomeReviews:   CP000800_GR
- KEGG:   ecw:EcE24377A_1713
- eggNOG:   COG2390
- GeneTree:   EBGT00050000009016
- HOGENOM:   HBG570280
- OMA:   LARIAWF
- ProtClustDB:   PRK15418
- BioCyc:   ECOL331111:ECE24377A_1713-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- InterPro:   IPR007324
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF04198 Sugar-bind

EC number: NA

Molecular weight: Translated: 33814; Mature: 33683

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINDSAISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGII
CCCCCCCCCCCCCCCHHHHHHEEEEEEECCCCHHHHHHHHCHHHHHHHHHHHCCCCCCEE
RVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQML
EEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCHHHE
AIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASS
EEECCHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCEEEEEEECCCCCCCH
ADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGA
HHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEECCCCCCCCEEEEECCCC
VGDILGYFFDAKGDVVTDIKIHNELIGLPLSSLKTIPVRVGVAGGENKAEAIAAAMKGGY
HHHHHHHHHCCCCCEEEEEEECCHHHCCCHHHCCEEEEEEEECCCCCHHHHHHHHHCCCE
INALVTDQDTAAAILRS
EEEEEECCHHHHHHHCC
>Mature Secondary Structure 
TINDSAISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGII
CCCCCCCCCCCCCCHHHHHHEEEEEEECCCCHHHHHHHHCHHHHHHHHHHHCCCCCCEE
RVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQML
EEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHCCHHHE
AIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGIGQLNAACSVNIIPAPLRASS
EEECCHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHCCCCEEEEEEECCCCCCCH
ADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGA
HHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEECCCCCCCCEEEEECCCC
VGDILGYFFDAKGDVVTDIKIHNELIGLPLSSLKTIPVRVGVAGGENKAEAIAAAMKGGY
HHHHHHHHHCCCCCEEEEEEECCHHHCCCHHHCCEEEEEEEECCCCCHHHHHHHHHCCCE
INALVTDQDTAAAILRS
EEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA