Click here to switch to the map view.

The map label for this gene is epaR [H]

Identifier: 157158728

GI number: 157158728

Start: 3198009

End: 3198776

Strand: Reverse

Name: epaR [H]

Synonym: EcE24377A_3182

Alternate gene names: 157158728

Gene position: 3198776-3198009 (Counterclockwise)

Preceding gene: 157158179

Following gene: 157159225

Centisome position: 64.24

GC content: 39.58

Gene sequence:

>768_bases
ATGGGGGAGGCGATACTCTATCAGTTGCATAGTCTGCTGGCTGCTACAGCGCTCGGTTTTTGCCGATTGGCACCAACTTT
CTATTTGTTACCATTTTTCGCCAGTGGGAATATACCAACAGTAGTTCGTCACCCAATAATAATAGTGGTATCATGTGCAT
TAGTTCAGCATTACCACTATGAATTATTGAACTTAAATGAAATCGATATTGCTTTGTTCGCTGCCAGAGAAATTATCATA
GGGCTGTTTATTGCATGCTTATTAGCATCCCCGTTTTGGATTTTCCTTGCTATAGGTAGCTTTATCGATAACCAACGCGG
TGCAACATTAAGTAGTACTTTGGATCCGGCTACAGGTGTCGATACCTCGGAATTAGCAAGATTATTTAACCTTTTCTCTG
CTGCGGTTTATCTTACTAAAGGTGGAATGAACTTTATTCTGGAAACTCTTTGGCAAAGCCATAATTTATGGCCTTCAGGC
AATTTTAATTTTCCTAAATTAGAGCCTTTATTCTCATATATTAATAACATAATGACTCATACTATCGTTTACGCAAGCCC
CGTGATTGCCGTTATGCTGGGCGGTGAGGCTGTCCTGGGATTGCTGGCATGTTATGCTTCACAACTAAATGCTTTTGCCA
TTTCACTGACTGTCAAAAGTGCGCTGGCATTTTTAATATTAATTATTTATTTTGCCCCAATACTGGCTGAACGAGTAATG
CCGTTATCCTTTTTCCCAGAACAATTGCAACTATACATTGAGAAATAG

Upstream 100 bases:

>100_bases
TGCGTAAGTATTTGCTTTTTTTTAATGAGCGGGTGGTATGGTGAAAAATTATATTCATTTGGTATCGAAATGCTGAATTT
AGCATTCGCGAGAGGATAGC

Downstream 100 bases:

>100_bases
AGTGTTTCATGGCCAATAAAACTGAAAAGCCAACACAAAAGAAACTCCAGGATGCTTCTAAAAAAGGGCAAATTCTAAAA
AGTAGAGACTTAACCATCTC

Product: type III secretion apparatus protein EpaR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MGEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRHPIIIVVSCALVQHYHYELLNLNEIDIALFAAREIII
GLFIACLLASPFWIFLAIGSFIDNQRGATLSSTLDPATGVDTSELARLFNLFSAAVYLTKGGMNFILETLWQSHNLWPSG
NFNFPKLEPLFSYINNIMTHTIVYASPVIAVMLGGEAVLGLLACYASQLNAFAISLTVKSALAFLILIIYFAPILAERVM
PLSFFPEQLQLYIEK

Sequences:

>Translated_255_residues
MGEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRHPIIIVVSCALVQHYHYELLNLNEIDIALFAAREIII
GLFIACLLASPFWIFLAIGSFIDNQRGATLSSTLDPATGVDTSELARLFNLFSAAVYLTKGGMNFILETLWQSHNLWPSG
NFNFPKLEPLFSYINNIMTHTIVYASPVIAVMLGGEAVLGLLACYASQLNAFAISLTVKSALAFLILIIYFAPILAERVM
PLSFFPEQLQLYIEK
>Mature_254_residues
GEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRHPIIIVVSCALVQHYHYELLNLNEIDIALFAAREIIIG
LFIACLLASPFWIFLAIGSFIDNQRGATLSSTLDPATGVDTSELARLFNLFSAAVYLTKGGMNFILETLWQSHNLWPSGN
FNFPKLEPLFSYINNIMTHTIVYASPVIAVMLGGEAVLGLLACYASQLNAFAISLTVKSALAFLILIIYFAPILAERVMP
LSFFPEQLQLYIEK

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells [H]

COG id: COG4791

COG function: function code U; Type III secretory pathway, component EscT

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliR/mopE/spaR family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002010
- InterPro:   IPR006304 [H]

Pfam domain/function: PF01311 Bac_export_1 [H]

EC number: NA

Molecular weight: Translated: 28157; Mature: 28025

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRHPIIIVVSCALVQHYHY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ELLNLNEIDIALFAAREIIIGLFIACLLASPFWIFLAIGSFIDNQRGATLSSTLDPATGV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCC
DTSELARLFNLFSAAVYLTKGGMNFILETLWQSHNLWPSGNFNFPKLEPLFSYINNIMTH
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TIVYASPVIAVMLGGEAVLGLLACYASQLNAFAISLTVKSALAFLILIIYFAPILAERVM
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PLSFFPEQLQLYIEK
CHHCCHHHHHHHHCC
>Mature Secondary Structure 
GEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRHPIIIVVSCALVQHYHY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ELLNLNEIDIALFAAREIIIGLFIACLLASPFWIFLAIGSFIDNQRGATLSSTLDPATGV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCC
DTSELARLFNLFSAAVYLTKGGMNFILETLWQSHNLWPSGNFNFPKLEPLFSYINNIMTH
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
TIVYASPVIAVMLGGEAVLGLLACYASQLNAFAISLTVKSALAFLILIIYFAPILAERVM
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PLSFFPEQLQLYIEK
CHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8404849; 11677609 [H]