| Definition | Escherichia coli E24377A, complete genome. |
|---|---|
| Accession | NC_009801 |
| Length | 4,979,619 |
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The map label for this gene is uvrD [H]
Identifier: 157156759
GI number: 157156759
Start: 3383223
End: 3385115
Strand: Reverse
Name: uvrD [H]
Synonym: EcE24377A_3362
Alternate gene names: 157156759
Gene position: 3385115-3383223 (Counterclockwise)
Preceding gene: 157156101
Following gene: 157155200
Centisome position: 67.98
GC content: 37.77
Gene sequence:
>1893_bases ATGAATCTATCAAATGCTCAGCGCCAGATCGTTGAAGCCCCTATGGATATAGCTATTCAAGTGCTTGCCTCAGCAGGTTC TGGAAAAACTCGTGTCTTAACAGAGCGTGTTCGATATATATTGAATAATACAAAGAGAGATGCTGTTATTGCCCTGACCT TTACGAATAAAGCAGCGGAAGAAATGAGTTCGCGTTTAAGTGATTTTGATCCAGATGAAGATAGGGTCTGGATTGCTACG ATTCACTCTGTTGCGCAGCGTATTTTAGAAAAATACGGACACACCATTGGTTTGCCATCAGATTTGTATATATATGATAG AGATAAGGATCGTATGGAAGTCTTTATGCAGTCTTTGCGTGAAGATGGTATTGATATAGATGAATATCTCTCCATTGCAG ATTCCAAGGAATTGAAAAATAGAGAGCGAAATCTGCAATCGTATATGGATATATTTTCAAAAATAAAGAGAGAGTTGCTT ACTGAGTTTGAGGTATCTGAGTTGTATCCAGATAATAATATCTGGAAAATATATCAAGATTATCAGGCTTCATTACTTAA TAGTGGCGGTATCGATTATGACGATATTTTAGTATATGCACATCGGATTCTGCTCACGCATGATTGGATAGCAAAAATAT ATCGTTCAAAATATAAACATGTTTGTGTTGATGAAGCTCAAGATCTTAATAAAGCGCAGTATGAATTTATTAAGGTGCTG TGCGGTGATGTGATAAAAAGTATTCTTATGGTAGGTGACCCTAATCAAATGATTTATGGTTTTAATGGGTCATCAAAAGA CTACTTTTGTGAAGATTTTATTAATGATTTTTTTCCTAATCAGTTTGAGTTAAAGGAGAATTATCGTAGTGCCAAAGCTA TTATTCGCGCAGCAAATAAGTTAAGACCGGGATCACAAGCAGAGATTGATTATGCCTTAGAGGGAGGCGTTAGAATCTCA GAATTTGCTTCAGAAGAAGATGAAGCTGATACGGTTGTCGCTACTATAAAGCATCTTCTGGAATTGAAAGTTCACGATGA GATTGAGGGGGATATTTCACTAAACAATATGGTTGTGATTGGCCGTAATCGGTTTGTTTTTGGCAAGCTTGAAAAATGCC TTAAAGAAAATTTGATTCCTTACTCTTTGAGGAAAGGAGAGAGAGCGTTAGAACCTTCGACTAGATTTGGAAAAGCCCTG GACTATGCCATTAGAGTGAAGTTGAATTCAAAGGATTGGGTTGATGGAAAAAAATTATGTCAAGTACTTTGCATATCAGA GCCGGCTGGCTGGACACCTGATGTATTGCGAGAGATGGCGGTTCAAATTTCATCATCAGATGATGATTACTCTATTGTAT TTGAAAAACTTCTTACTACTATTGATAGCTTAAATATTGAAAATCCTAAAATTCCCAAGCTAATAAAGGAATTTAATGCT CTTCTTACATCGTTAGTTGAAAATCACAATGGTATTTCAGACGATAAAATAGAAGACGTCAAGTTGAGTATTGAGGAGCT TAAAGAGTTTAGTGGTATGTGGACTCGATTTAAGCGTAAGGGGTTAGGTGATTCATTAGTTGCATTTAGGAACGCATTGG CATTGGGGCAACTAGCTGAAAGTAGTATGGATGAAGGCTTAACTTTAAGTACAGTGCATACTATGAAGGGACTGGAAAAG GATATCGTGTTCTTGATAGGTATGTGTGAAGGGGTTTTCCCGGATTACAGAGCTAGAACGCCCAAAGAGCTTGAAGAGGA ACGCAATAACGCTTTTGTTGCGGTGACAAGAGCGAAGCGTTGGCTGTACGTTTCTTATCCTAGGCAGAGGATGATGCCTT GGGGCGACCTTAGGTTTCAGCAAAAATCCCGATTTGTCAGTGAAATAGAATAA
Upstream 100 bases:
>100_bases TATGCAAAAGCAATCACAGATAATTTGATTAAATTACCGAAAGAAAAATTTCCTCAGAAGATAATTGAATTATTCAAACA AATTGAGTCGGGAGTTTGAT
Downstream 100 bases:
>100_bases GCACAATATCAAATTATTGATGTAGGAGAGTATATTATTACTCTCCTTGAGCAATATTATTCATCTCAGAGCCGTTTTGT TCTCTTAGAGTTCTCCTTAA
Product: UvrD family helicase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 630; Mature: 630
Protein sequence:
>630_residues MNLSNAQRQIVEAPMDIAIQVLASAGSGKTRVLTERVRYILNNTKRDAVIALTFTNKAAEEMSSRLSDFDPDEDRVWIAT IHSVAQRILEKYGHTIGLPSDLYIYDRDKDRMEVFMQSLREDGIDIDEYLSIADSKELKNRERNLQSYMDIFSKIKRELL TEFEVSELYPDNNIWKIYQDYQASLLNSGGIDYDDILVYAHRILLTHDWIAKIYRSKYKHVCVDEAQDLNKAQYEFIKVL CGDVIKSILMVGDPNQMIYGFNGSSKDYFCEDFINDFFPNQFELKENYRSAKAIIRAANKLRPGSQAEIDYALEGGVRIS EFASEEDEADTVVATIKHLLELKVHDEIEGDISLNNMVVIGRNRFVFGKLEKCLKENLIPYSLRKGERALEPSTRFGKAL DYAIRVKLNSKDWVDGKKLCQVLCISEPAGWTPDVLREMAVQISSSDDDYSIVFEKLLTTIDSLNIENPKIPKLIKEFNA LLTSLVENHNGISDDKIEDVKLSIEELKEFSGMWTRFKRKGLGDSLVAFRNALALGQLAESSMDEGLTLSTVHTMKGLEK DIVFLIGMCEGVFPDYRARTPKELEEERNNAFVAVTRAKRWLYVSYPRQRMMPWGDLRFQQKSRFVSEIE
Sequences:
>Translated_630_residues MNLSNAQRQIVEAPMDIAIQVLASAGSGKTRVLTERVRYILNNTKRDAVIALTFTNKAAEEMSSRLSDFDPDEDRVWIAT IHSVAQRILEKYGHTIGLPSDLYIYDRDKDRMEVFMQSLREDGIDIDEYLSIADSKELKNRERNLQSYMDIFSKIKRELL TEFEVSELYPDNNIWKIYQDYQASLLNSGGIDYDDILVYAHRILLTHDWIAKIYRSKYKHVCVDEAQDLNKAQYEFIKVL CGDVIKSILMVGDPNQMIYGFNGSSKDYFCEDFINDFFPNQFELKENYRSAKAIIRAANKLRPGSQAEIDYALEGGVRIS EFASEEDEADTVVATIKHLLELKVHDEIEGDISLNNMVVIGRNRFVFGKLEKCLKENLIPYSLRKGERALEPSTRFGKAL DYAIRVKLNSKDWVDGKKLCQVLCISEPAGWTPDVLREMAVQISSSDDDYSIVFEKLLTTIDSLNIENPKIPKLIKEFNA LLTSLVENHNGISDDKIEDVKLSIEELKEFSGMWTRFKRKGLGDSLVAFRNALALGQLAESSMDEGLTLSTVHTMKGLEK DIVFLIGMCEGVFPDYRARTPKELEEERNNAFVAVTRAKRWLYVSYPRQRMMPWGDLRFQQKSRFVSEIE >Mature_630_residues MNLSNAQRQIVEAPMDIAIQVLASAGSGKTRVLTERVRYILNNTKRDAVIALTFTNKAAEEMSSRLSDFDPDEDRVWIAT IHSVAQRILEKYGHTIGLPSDLYIYDRDKDRMEVFMQSLREDGIDIDEYLSIADSKELKNRERNLQSYMDIFSKIKRELL TEFEVSELYPDNNIWKIYQDYQASLLNSGGIDYDDILVYAHRILLTHDWIAKIYRSKYKHVCVDEAQDLNKAQYEFIKVL CGDVIKSILMVGDPNQMIYGFNGSSKDYFCEDFINDFFPNQFELKENYRSAKAIIRAANKLRPGSQAEIDYALEGGVRIS EFASEEDEADTVVATIKHLLELKVHDEIEGDISLNNMVVIGRNRFVFGKLEKCLKENLIPYSLRKGERALEPSTRFGKAL DYAIRVKLNSKDWVDGKKLCQVLCISEPAGWTPDVLREMAVQISSSDDDYSIVFEKLLTTIDSLNIENPKIPKLIKEFNA LLTSLVENHNGISDDKIEDVKLSIEELKEFSGMWTRFKRKGLGDSLVAFRNALALGQLAESSMDEGLTLSTVHTMKGLEK DIVFLIGMCEGVFPDYRARTPKELEEERNNAFVAVTRAKRWLYVSYPRQRMMPWGDLRFQQKSRFVSEIE
Specific function: May process damage occurring in non-replicating regions of DNA to produce recombinational intermediates for sister strand recombinational exchange [H]
COG id: COG0210
COG function: function code L; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]
Homologues:
Organism=Escherichia coli, GI2367296, Length=673, Percent_Identity=28.3803863298663, Blast_Score=203, Evalue=3e-53, Organism=Escherichia coli, GI48994965, Length=403, Percent_Identity=28.287841191067, Blast_Score=119, Evalue=8e-28, Organism=Saccharomyces cerevisiae, GI6322369, Length=403, Percent_Identity=28.287841191067, Blast_Score=120, Evalue=8e-28,
Paralogues:
None
Copy number: 3000 [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005753 - InterPro: IPR013986 - InterPro: IPR014017 - InterPro: IPR000212 - InterPro: IPR014016 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 72352; Mature: 72352
Theoretical pI: Translated: 5.01; Mature: 5.01
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.7 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNLSNAQRQIVEAPMDIAIQVLASAGSGKTRVLTERVRYILNNTKRDAVIALTFTNKAAE CCCCHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHH EMSSRLSDFDPDEDRVWIATIHSVAQRILEKYGHTIGLPSDLYIYDRDKDRMEVFMQSLR HHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHCCCEECCCCCEEEEECCHHHHHHHHHHHH EDGIDIDEYLSIADSKELKNRERNLQSYMDIFSKIKRELLTEFEVSELYPDNNIWKIYQD HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH YQASLLNSGGIDYDDILVYAHRILLTHDWIAKIYRSKYKHVCVDEAQDLNKAQYEFIKVL HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHHHHHHHH CGDVIKSILMVGDPNQMIYGFNGSSKDYFCEDFINDFFPNQFELKENYRSAKAIIRAANK HHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH LRPGSQAEIDYALEGGVRISEFASEEDEADTVVATIKHLLELKVHDEIEGDISLNNMVVI CCCCCCCCEEEECCCCEEHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEE GRNRFVFGKLEKCLKENLIPYSLRKGERALEPSTRFGKALDYAIRVKLNSKDWVDGKKLC CCCCEEHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHCCEEEEEEECCCCCCCHHHHH QVLCISEPAGWTPDVLREMAVQISSSDDDYSIVFEKLLTTIDSLNIENPKIPKLIKEFNA HHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH LLTSLVENHNGISDDKIEDVKLSIEELKEFSGMWTRFKRKGLGDSLVAFRNALALGQLAE HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH SSMDEGLTLSTVHTMKGLEKDIVFLIGMCEGVFPDYRARTPKELEEERNNAFVAVTRAKR HHHCCCCEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEEECCE WLYVSYPRQRMMPWGDLRFQQKSRFVSEIE EEEEECCHHHCCCCHHCCHHHHHHHHHHCC >Mature Secondary Structure MNLSNAQRQIVEAPMDIAIQVLASAGSGKTRVLTERVRYILNNTKRDAVIALTFTNKAAE CCCCHHHHHHHHCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHH EMSSRLSDFDPDEDRVWIATIHSVAQRILEKYGHTIGLPSDLYIYDRDKDRMEVFMQSLR HHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHCCCEECCCCCEEEEECCHHHHHHHHHHHH EDGIDIDEYLSIADSKELKNRERNLQSYMDIFSKIKRELLTEFEVSELYPDNNIWKIYQD HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH YQASLLNSGGIDYDDILVYAHRILLTHDWIAKIYRSKYKHVCVDEAQDLNKAQYEFIKVL HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCHHHHHHHHHHH CGDVIKSILMVGDPNQMIYGFNGSSKDYFCEDFINDFFPNQFELKENYRSAKAIIRAANK HHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH LRPGSQAEIDYALEGGVRISEFASEEDEADTVVATIKHLLELKVHDEIEGDISLNNMVVI CCCCCCCCEEEECCCCEEHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEEE GRNRFVFGKLEKCLKENLIPYSLRKGERALEPSTRFGKALDYAIRVKLNSKDWVDGKKLC CCCCEEHHHHHHHHHHCCCCCHHHCCCCCCCCCHHHHHHCCEEEEEEECCCCCCCHHHHH QVLCISEPAGWTPDVLREMAVQISSSDDDYSIVFEKLLTTIDSLNIENPKIPKLIKEFNA HHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH LLTSLVENHNGISDDKIEDVKLSIEELKEFSGMWTRFKRKGLGDSLVAFRNALALGQLAE HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH SSMDEGLTLSTVHTMKGLEKDIVFLIGMCEGVFPDYRARTPKELEEERNNAFVAVTRAKR HHHCCCCEEEHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEEEEEEECCE WLYVSYPRQRMMPWGDLRFQQKSRFVSEIE EEEEECCHHHCCCCHHCCHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8294031; 7542800; 3259573 [H]