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The map label for this gene is tmcA [H]

Identifier: 156978246

GI number: 156978246

Start: 2126625

End: 2128643

Strand: Direct

Name: tmcA [H]

Synonym: VIBHAR_07052

Alternate gene names: 156978246

Gene position: 2126625-2128643 (Clockwise)

Preceding gene: 156978244

Following gene: 156978247

Centisome position: 96.49

GC content: 45.32

Gene sequence:

>2019_bases
ATGCTCGCACAATCTGAATTCCTTTCTCTGCTTCAGCTCCAATCTTACAAAGCCTTTCAACGTAATGGCGTGGTGATTTA
TGGTGATGCCGATTGGCAAAACGCCTTGATTGCCGACTTCCATCAAAAGCAGCAAAATCAGACTTGGTTTTGCGTAGGGG
AGTGGCAACTAGAAAATGCCCACTGCGTAAATGCAAAACAAGGCAATATGTTGCTCGGTCGCGAGTGTGACGTTTTGCTG
TTTGATGCGAGAAAAGAGCTTGATGCTAACAGTTTTACTTCGGCTCTTGGCGCGCTCGTCGGCGGTGGACTATTGATTGT
GGTAGTCAATAAAAAACAAGAAGCGGATGAAGCCGAACTGTGGATGCAAACGCAATGGCAACAACTCACCGTTATTGAGG
AAAATTCACCATTACCTCAACTACCAGATTTCATTCAAGCGGAAAAAGCGCATCAGTATAGCGAGCAAACTGAAGCGGTT
TCTTTTATCGAAAAAGTGGTGACAGGGCATCGTAAACGTCCGTTAGTATTAACCGCCGATCGTGGTCGAGGAAAAACCAG
TGCGTTAGGCATTGCATGCGCGCAGCTTTTAGAGCAAAAGCCACTGCGAATTCTTGTCACAGCGCCAAGCATCAAAGCGG
TTGAACCTGTTTATCAGCACGCGCAGAGAATGCTATCAACCGCACAGCGCGTTAAGAAAGACCGATTAGAAGCGGGGCTG
GGTTACATTCAGTTTATTGCGCCGGATGAATTACTCTCAGCTTTACCTGAGTGTGATTTGTTGTTGGTTGATGAAGCTGC
TGCGATTCCGGTTCCTATGCTCAAGCAGATTACTGAGCAATATCATCGCCTCGTCTTTTCAACCACCATTCATGGTTATG
AAGGTTGTGGCCGTGGCTTCGCGCTTAAGTTTGTTGATTGGCTACAAAAGCAAAGACCTGGAACGAAGCTTTGTCATCTT
CAACAACCTATTCGATGGGCAGTAAATGACAACTTGGAATCTTGGCTGTACCAAGCATTTTTGCTGGATGCAGAACTTAC
CCCGAGCCAACCTGCCGAGCTTGGTGACATGTCATTAATCAACCTCCGTAAGTCAGCGTTGATTTCTAATCCTTCCGTAT
TGAAAACGTGCTTCGCGTTACTTGTGAATGCGCACTATCAAACCTCGCCAAATGATTTGTTGCATCTTCTGCAAGATGAA
CATTGCCAGATTTACGTAGCTCAGAATAAGAATGAAATTGTCGGGGTGATGTTAACGGTGGAGGAGGGTAACCTTGATTC
GAATCTCGTTAAAGATATTCAGCTTGGGAAACGTCGTCCGAAAGGGCATCTGACGCCAGTGACCCTCATCAATCAACTTG
GTTACGCTGATGTGGGTGCGCTTTCTACTTTGCGAGTGATGCGAATTGCGGTGAATCCAGAGTTGCAAGGGCAGGGCATT
GGCCAACAAATGTTGAAGCTGTTAGAACAAACTACGCCGCCTCATATTTCTTATTTGTCCACCAGCTTTGGTGCAACAGA
AGAACTGATTACGTTTTGGAAGCAATCTGGTTTTGAATCCATTCGTCTTGGAAGTATGCGAGATGCGGCAAGTGGGTGTT
ACTCGTTGTTGATGGTTCGTCAATGTGGCTCACAACAAAGTTGGATAAACGAAGCTAAATCGTTGTTCGAAGAACTGTTG
CCATTGAGTGCGGCGTCTACTTATCCTAAGTTAGAGCCAAGTTTGTTGCGTGCGCTCTTGCCAGCCTCGGTATCTACTTG
CCAGTCCCATTTAACGAAGCGTACTTTAATCGAGTGTTATGCTCAAGGTGGAAACAATTTTGAATCTGTCTCTGTTTGGA
TTCAGCAATGGTTACTGCAATGTGGTTTGGCTGATGTGTCTGACTTGATGATCAGTAAATTATTCTTAAACAAAGACTGG
AGTGAGTGCGCTAAGCAATATGGCTTGCCGGGACGTAAGCAGGTTGAAGCACATATAAGAAACGAGCTACAAGTTTTGAT
AGCTAAATTTACAGTGTAA

Upstream 100 bases:

>100_bases
AGTTAGCCTTCGGGCGGTTTTTTTATGTCTGCAATTTGACGAAGTCTCCATGAATCCAGATGTGATAACATGGCGTTAGT
TCAACGCTTGGATACACGTA

Downstream 100 bases:

>100_bases
ACAGAGCGAGTAATTTACACTGTAAAAGTAGATTTGAAAGGGGGAGGGTTTACACTGTAAATCCTCCCTTTTGATTTGGC
ACTTTTTAGTCAAGGTCTAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MLAQSEFLSLLQLQSYKAFQRNGVVIYGDADWQNALIADFHQKQQNQTWFCVGEWQLENAHCVNAKQGNMLLGRECDVLL
FDARKELDANSFTSALGALVGGGLLIVVVNKKQEADEAELWMQTQWQQLTVIEENSPLPQLPDFIQAEKAHQYSEQTEAV
SFIEKVVTGHRKRPLVLTADRGRGKTSALGIACAQLLEQKPLRILVTAPSIKAVEPVYQHAQRMLSTAQRVKKDRLEAGL
GYIQFIAPDELLSALPECDLLLVDEAAAIPVPMLKQITEQYHRLVFSTTIHGYEGCGRGFALKFVDWLQKQRPGTKLCHL
QQPIRWAVNDNLESWLYQAFLLDAELTPSQPAELGDMSLINLRKSALISNPSVLKTCFALLVNAHYQTSPNDLLHLLQDE
HCQIYVAQNKNEIVGVMLTVEEGNLDSNLVKDIQLGKRRPKGHLTPVTLINQLGYADVGALSTLRVMRIAVNPELQGQGI
GQQMLKLLEQTTPPHISYLSTSFGATEELITFWKQSGFESIRLGSMRDAASGCYSLLMVRQCGSQQSWINEAKSLFEELL
PLSAASTYPKLEPSLLRALLPASVSTCQSHLTKRTLIECYAQGGNNFESVSVWIQQWLLQCGLADVSDLMISKLFLNKDW
SECAKQYGLPGRKQVEAHIRNELQVLIAKFTV

Sequences:

>Translated_672_residues
MLAQSEFLSLLQLQSYKAFQRNGVVIYGDADWQNALIADFHQKQQNQTWFCVGEWQLENAHCVNAKQGNMLLGRECDVLL
FDARKELDANSFTSALGALVGGGLLIVVVNKKQEADEAELWMQTQWQQLTVIEENSPLPQLPDFIQAEKAHQYSEQTEAV
SFIEKVVTGHRKRPLVLTADRGRGKTSALGIACAQLLEQKPLRILVTAPSIKAVEPVYQHAQRMLSTAQRVKKDRLEAGL
GYIQFIAPDELLSALPECDLLLVDEAAAIPVPMLKQITEQYHRLVFSTTIHGYEGCGRGFALKFVDWLQKQRPGTKLCHL
QQPIRWAVNDNLESWLYQAFLLDAELTPSQPAELGDMSLINLRKSALISNPSVLKTCFALLVNAHYQTSPNDLLHLLQDE
HCQIYVAQNKNEIVGVMLTVEEGNLDSNLVKDIQLGKRRPKGHLTPVTLINQLGYADVGALSTLRVMRIAVNPELQGQGI
GQQMLKLLEQTTPPHISYLSTSFGATEELITFWKQSGFESIRLGSMRDAASGCYSLLMVRQCGSQQSWINEAKSLFEELL
PLSAASTYPKLEPSLLRALLPASVSTCQSHLTKRTLIECYAQGGNNFESVSVWIQQWLLQCGLADVSDLMISKLFLNKDW
SECAKQYGLPGRKQVEAHIRNELQVLIAKFTV
>Mature_672_residues
MLAQSEFLSLLQLQSYKAFQRNGVVIYGDADWQNALIADFHQKQQNQTWFCVGEWQLENAHCVNAKQGNMLLGRECDVLL
FDARKELDANSFTSALGALVGGGLLIVVVNKKQEADEAELWMQTQWQQLTVIEENSPLPQLPDFIQAEKAHQYSEQTEAV
SFIEKVVTGHRKRPLVLTADRGRGKTSALGIACAQLLEQKPLRILVTAPSIKAVEPVYQHAQRMLSTAQRVKKDRLEAGL
GYIQFIAPDELLSALPECDLLLVDEAAAIPVPMLKQITEQYHRLVFSTTIHGYEGCGRGFALKFVDWLQKQRPGTKLCHL
QQPIRWAVNDNLESWLYQAFLLDAELTPSQPAELGDMSLINLRKSALISNPSVLKTCFALLVNAHYQTSPNDLLHLLQDE
HCQIYVAQNKNEIVGVMLTVEEGNLDSNLVKDIQLGKRRPKGHLTPVTLINQLGYADVGALSTLRVMRIAVNPELQGQGI
GQQMLKLLEQTTPPHISYLSTSFGATEELITFWKQSGFESIRLGSMRDAASGCYSLLMVRQCGSQQSWINEAKSLFEELL
PLSAASTYPKLEPSLLRALLPASVSTCQSHLTKRTLIECYAQGGNNFESVSVWIQQWLLQCGLADVSDLMISKLFLNKDW
SECAKQYGLPGRKQVEAHIRNELQVLIAKFTV

Specific function: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) [H]

COG id: COG1444

COG function: function code R; Predicted P-loop ATPase fused to an acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI221316723, Length=497, Percent_Identity=26.5593561368209, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI221316741, Length=497, Percent_Identity=26.5593561368209, Blast_Score=118, Evalue=2e-26,
Organism=Escherichia coli, GI1788818, Length=512, Percent_Identity=32.6171875, Blast_Score=221, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17507621, Length=474, Percent_Identity=24.6835443037975, Blast_Score=127, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324197, Length=532, Percent_Identity=25.3759398496241, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24640662, Length=532, Percent_Identity=28.0075187969925, Blast_Score=167, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR007807 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF05127 DUF699 [H]

EC number: NA

Molecular weight: Translated: 75136; Mature: 75136

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAQSEFLSLLQLQSYKAFQRNGVVIYGDADWQNALIADFHQKQQNQTWFCVGEWQLENA
CCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEEECCC
HCVNAKQGNMLLGRECDVLLFDARKELDANSFTSALGALVGGGLLIVVVNKKQEADEAEL
EEECCCCCCEEECCCCCEEEECCHHHCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHH
WMQTQWQQLTVIEENSPLPQLPDFIQAEKAHQYSEQTEAVSFIEKVVTGHRKRPLVLTAD
HHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
RGRGKTSALGIACAQLLEQKPLRILVTAPSIKAVEPVYQHAQRMLSTAQRVKKDRLEAGL
CCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GYIQFIAPDELLSALPECDLLLVDEAAAIPVPMLKQITEQYHRLVFSTTIHGYEGCGRGF
CEEEEECHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALKFVDWLQKQRPGTKLCHLQQPIRWAVNDNLESWLYQAFLLDAELTPSQPAELGDMSLI
HHHHHHHHHHCCCCCCHHHHCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
NLRKSALISNPSVLKTCFALLVNAHYQTSPNDLLHLLQDEHCQIYVAQNKNEIVGVMLTV
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEEEEE
EEGNLDSNLVKDIQLGKRRPKGHLTPVTLINQLGYADVGALSTLRVMRIAVNPELQGQGI
ECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCCCCC
GQQMLKLLEQTTPPHISYLSTSFGATEELITFWKQSGFESIRLGSMRDAASGCYSLLMVR
HHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHH
QCGSQQSWINEAKSLFEELLPLSAASTYPKLEPSLLRALLPASVSTCQSHLTKRTLIECY
HCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGGNNFESVSVWIQQWLLQCGLADVSDLMISKLFLNKDWSECAKQYGLPGRKQVEAHIR
HCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHH
NELQVLIAKFTV
HHHHHHHHHHCC
>Mature Secondary Structure
MLAQSEFLSLLQLQSYKAFQRNGVVIYGDADWQNALIADFHQKQQNQTWFCVGEWQLENA
CCCHHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEEEECCC
HCVNAKQGNMLLGRECDVLLFDARKELDANSFTSALGALVGGGLLIVVVNKKQEADEAEL
EEECCCCCCEEECCCCCEEEECCHHHCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHH
WMQTQWQQLTVIEENSPLPQLPDFIQAEKAHQYSEQTEAVSFIEKVVTGHRKRPLVLTAD
HHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEC
RGRGKTSALGIACAQLLEQKPLRILVTAPSIKAVEPVYQHAQRMLSTAQRVKKDRLEAGL
CCCCCHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GYIQFIAPDELLSALPECDLLLVDEAAAIPVPMLKQITEQYHRLVFSTTIHGYEGCGRGF
CEEEEECHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALKFVDWLQKQRPGTKLCHLQQPIRWAVNDNLESWLYQAFLLDAELTPSQPAELGDMSLI
HHHHHHHHHHCCCCCCHHHHCCCHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
NLRKSALISNPSVLKTCFALLVNAHYQTSPNDLLHLLQDEHCQIYVAQNKNEIVGVMLTV
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEEECCCCCEEEEEEEE
EEGNLDSNLVKDIQLGKRRPKGHLTPVTLINQLGYADVGALSTLRVMRIAVNPELQGQGI
ECCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHEEECCCCCCCCC
GQQMLKLLEQTTPPHISYLSTSFGATEELITFWKQSGFESIRLGSMRDAASGCYSLLMVR
HHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHH
QCGSQQSWINEAKSLFEELLPLSAASTYPKLEPSLLRALLPASVSTCQSHLTKRTLIECY
HCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQGGNNFESVSVWIQQWLLQCGLADVSDLMISKLFLNKDWSECAKQYGLPGRKQVEAHIR
HCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHH
NELQVLIAKFTV
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]