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The map label for this gene is lacF [H]

Identifier: 156978135

GI number: 156978135

Start: 2035807

End: 2036796

Strand: Reverse

Name: lacF [H]

Synonym: VIBHAR_06940

Alternate gene names: 156978135

Gene position: 2036796-2035807 (Counterclockwise)

Preceding gene: 156978136

Following gene: 156978134

Centisome position: 92.41

GC content: 47.78

Gene sequence:

>990_bases
ATGAATCATGCAGCGAGCAAGGTTATGGAAACTCCAGAAAGTAAGGGCACTTTTTCTCGTCTGAATTTGAAAGCGCTTAC
ACCTTATGGATTCCTATTGCCGTTTTTGATCATCTTTTCAGTGTTCGGAATTTTTCCGTTGCTGTTTTCTATTTTTCTTT
CTTTTCATGAGTGGAACCCAGTCGAGGGTTTGGGCGCTATGGACTATGTGGGGTTCGAAAACTACCACATTGCACTGACA
GACCCGTGGCTGTGGCGCTCATTGAAGAACACGCTTTGGCTAGCGATCACATCAGGCGTGGCTCAACACTTAGTTGCCTT
ACCTGTGGCGTACATCTTGGTGTCGCTGGGTGACCGTTTCCGTCATTGGTTGACGTCGGCTTACTTTCTACCGTTCATCA
CATCTACGGTGGCAGCGTCGCTTATCTTCTTCAATATGTACTCACCAAACTCGGGCATCATCAACCAAAGCTTGATGGCA
CTGGCAGACAGTACCTTGTTTGGTTGGGCATTCTCTTGGGTGAACGACTTCCAGCCAATCCGTTGGTTAGATGACGCGAC
CATGGTTAAGCCTTCCATCGCCATCATGGTGTTCTGGAAATACACCGGTTTCAACATCGTGCTTTACACCACTGGCTTGA
TGACGATTCCGAGAGACATCCTAGAAGCGGCTCGTATGGACGGCGCAAACGCATGGCGTCGATTCTGGAGCATTTCACTA
CCAATGATTCGTCCATTCATCTTCTTTGCGGTCACCATGACCATCATCGGTAACTTGCAGTTGTTCGAAGAACCATTTGT
TCTGACGCGCGGTACTGGTGGTACGGGTCAGTCTGGCTTAACCATCTCTATGTACCTCTACAAAGTGGGTTGGGAATGGT
TAGAAATGGGTACAGCGTCAGCAATTTCATGTCTGCTCTTTACCTTGATTGCAGGCTGTACAGCGGTTCAATTCTTCTTC
TTCGGTAAGAAAGGTCTAGGGGAGCAATAA

Upstream 100 bases:

>100_bases
AGAGCGCATGATCAAGCGTCGTACGCGTAATCTGTAATTTTTTGCCAATACTTAAGGCAGGAAGGGGGCATGTCCCCCTT
CTGGGTAAGAGGTCGTTACT

Downstream 100 bases:

>100_bases
GATGAGTACTAACACTTTACCTGCGGCGCAGCGTTGGCGTCCTAGCGATCGCAGCATCGAGATCTTTACCAAGATACTGA
TGGTGATGCTCGGCACTGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNHAASKVMETPESKGTFSRLNLKALTPYGFLLPFLIIFSVFGIFPLLFSIFLSFHEWNPVEGLGAMDYVGFENYHIALT
DPWLWRSLKNTLWLAITSGVAQHLVALPVAYILVSLGDRFRHWLTSAYFLPFITSTVAASLIFFNMYSPNSGIINQSLMA
LADSTLFGWAFSWVNDFQPIRWLDDATMVKPSIAIMVFWKYTGFNIVLYTTGLMTIPRDILEAARMDGANAWRRFWSISL
PMIRPFIFFAVTMTIIGNLQLFEEPFVLTRGTGGTGQSGLTISMYLYKVGWEWLEMGTASAISCLLFTLIAGCTAVQFFF
FGKKGLGEQ

Sequences:

>Translated_329_residues
MNHAASKVMETPESKGTFSRLNLKALTPYGFLLPFLIIFSVFGIFPLLFSIFLSFHEWNPVEGLGAMDYVGFENYHIALT
DPWLWRSLKNTLWLAITSGVAQHLVALPVAYILVSLGDRFRHWLTSAYFLPFITSTVAASLIFFNMYSPNSGIINQSLMA
LADSTLFGWAFSWVNDFQPIRWLDDATMVKPSIAIMVFWKYTGFNIVLYTTGLMTIPRDILEAARMDGANAWRRFWSISL
PMIRPFIFFAVTMTIIGNLQLFEEPFVLTRGTGGTGQSGLTISMYLYKVGWEWLEMGTASAISCLLFTLIAGCTAVQFFF
FGKKGLGEQ
>Mature_329_residues
MNHAASKVMETPESKGTFSRLNLKALTPYGFLLPFLIIFSVFGIFPLLFSIFLSFHEWNPVEGLGAMDYVGFENYHIALT
DPWLWRSLKNTLWLAITSGVAQHLVALPVAYILVSLGDRFRHWLTSAYFLPFITSTVAASLIFFNMYSPNSGIINQSLMA
LADSTLFGWAFSWVNDFQPIRWLDDATMVKPSIAIMVFWKYTGFNIVLYTTGLMTIPRDILEAARMDGANAWRRFWSISL
PMIRPFIFFAVTMTIIGNLQLFEEPFVLTRGTGGTGQSGLTISMYLYKVGWEWLEMGTASAISCLLFTLIAGCTAVQFFF
FGKKGLGEQ

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787570, Length=268, Percent_Identity=27.6119402985075, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789861, Length=305, Percent_Identity=25.5737704918033, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37113; Mature: 37113

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHAASKVMETPESKGTFSRLNLKALTPYGFLLPFLIIFSVFGIFPLLFSIFLSFHEWNP
CCCHHHHHHHCCCCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VEGLGAMDYVGFENYHIALTDPWLWRSLKNTLWLAITSGVAQHLVALPVAYILVSLGDRF
CCCCCCHHCCCCCCEEEEEECHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHWLTSAYFLPFITSTVAASLIFFNMYSPNSGIINQSLMALADSTLFGWAFSWVNDFQPI
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
RWLDDATMVKPSIAIMVFWKYTGFNIVLYTTGLMTIPRDILEAARMDGANAWRRFWSISL
EECCCCHHCCCCEEEEEEEEECCCEEEEEECCHHHCCHHHHHHHHCCCHHHHHHHHHCCC
PMIRPFIFFAVTMTIIGNLQLFEEPFVLTRGTGGTGQSGLTISMYLYKVGWEWLEMGTAS
HHHHHHHHHHHHHHHHCCHHEECCCEEEEECCCCCCCCCCEEEEHHHHHCHHHHHHCHHH
AISCLLFTLIAGCTAVQFFFFGKKGLGEQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNHAASKVMETPESKGTFSRLNLKALTPYGFLLPFLIIFSVFGIFPLLFSIFLSFHEWNP
CCCHHHHHHHCCCCCCCHHEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VEGLGAMDYVGFENYHIALTDPWLWRSLKNTLWLAITSGVAQHLVALPVAYILVSLGDRF
CCCCCCHHCCCCCCEEEEEECHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
RHWLTSAYFLPFITSTVAASLIFFNMYSPNSGIINQSLMALADSTLFGWAFSWVNDFQPI
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
RWLDDATMVKPSIAIMVFWKYTGFNIVLYTTGLMTIPRDILEAARMDGANAWRRFWSISL
EECCCCHHCCCCEEEEEEEEECCCEEEEEECCHHHCCHHHHHHHHCCCHHHHHHHHHCCC
PMIRPFIFFAVTMTIIGNLQLFEEPFVLTRGTGGTGQSGLTISMYLYKVGWEWLEMGTAS
HHHHHHHHHHHHHHHHCCHHEECCCEEEEECCCCCCCCCCEEEEHHHHHCHHHHHHCHHH
AISCLLFTLIAGCTAVQFFFFGKKGLGEQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]