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The map label for this gene is yafC [H]

Identifier: 156978111

GI number: 156978111

Start: 2013402

End: 2014220

Strand: Reverse

Name: yafC [H]

Synonym: VIBHAR_06916

Alternate gene names: 156978111

Gene position: 2014220-2013402 (Counterclockwise)

Preceding gene: 156978116

Following gene: 156978107

Centisome position: 91.39

GC content: 40.05

Gene sequence:

>819_bases
TTGTCTAAAGCCGCTGAAGAGCTAGGAATCAATGCCTCTACTGTAAGCCGTAAGATATCGGAAATAGAAGCATACTACGG
CGTCAAACTCCTCATACGTTCAACGCGAGCACTTAACCTAACTGAGGAGGGAAAAGCACTCTACCGCTACTTTCAAAATG
TGGACGATGTTTTAAGGCGTTCAGAAGATGAAATAATGCACCACCAACTTGAACCCACAGGCATTTTGAAAGTTGTCGTA
CCTGTTGACCTTGGTAACCTCCTACTTCAAGACGCCCTCGTGAGTTTTTCCCAAAAGTACCCTAAAGTTTTGCTCGACCT
TGATTTTTCTAATCGTCAAGTCGATATGCTTGAAGAAGGTATCGACATTTGGTTTTGCATTGGAGAAGTAAACAGTAAGA
GCTTGATTTCAAGTGAGTTATTATCATATAGACGATACCTTATGGCATCAAAGACATATCTTTTAGAATACGGCGAAATT
GGGTCTATTGCTGACCTAAAAGCGCCTCATAGACAGCTCAAATCTAAAAATCCATTCATTTATCAAGAGTCAGATAAATC
AGTACTTAAACAACTACCTGTGGCATTGACAGTCAATAGCGGCTATACCATTTTCAAAGCTTGTACTTCAGGTCTAGGAC
TAGCTTTCATCATGTCTAGCCTAGTAGAGAAATATGATACCGATAAAACGTTAGTACCCGTCCTTCCCAACGAAATCTAT
CAGCAATCGTCTGTTAACATGGTATATAAAGAGCGAAAACTAAAGCCAATGCGCGTTGAATACTTCTTAGACCACATGAA
GAGTTACTTTCTTGTTTGA

Upstream 100 bases:

>100_bases
GTTAAATGGCTCGAAATCAGGAACAGTTTTGCACAGAAACAATAATCGCTTTGACTTAAACACACTTGTCATCTTTCGGC
GTGTAGTAGACCTAAACTCG

Downstream 100 bases:

>100_bases
AGTCTTATTAAGAAAGGGCACCGTTGTGCCCTTTTGGCTTTTATTGAGATAGTTATACCCAAGTAACCTCGAGATGCTAG
GTTCAGCGAGACTGACTTGG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MSKAAEELGINASTVSRKISEIEAYYGVKLLIRSTRALNLTEEGKALYRYFQNVDDVLRRSEDEIMHHQLEPTGILKVVV
PVDLGNLLLQDALVSFSQKYPKVLLDLDFSNRQVDMLEEGIDIWFCIGEVNSKSLISSELLSYRRYLMASKTYLLEYGEI
GSIADLKAPHRQLKSKNPFIYQESDKSVLKQLPVALTVNSGYTIFKACTSGLGLAFIMSSLVEKYDTDKTLVPVLPNEIY
QQSSVNMVYKERKLKPMRVEYFLDHMKSYFLV

Sequences:

>Translated_272_residues
MSKAAEELGINASTVSRKISEIEAYYGVKLLIRSTRALNLTEEGKALYRYFQNVDDVLRRSEDEIMHHQLEPTGILKVVV
PVDLGNLLLQDALVSFSQKYPKVLLDLDFSNRQVDMLEEGIDIWFCIGEVNSKSLISSELLSYRRYLMASKTYLLEYGEI
GSIADLKAPHRQLKSKNPFIYQESDKSVLKQLPVALTVNSGYTIFKACTSGLGLAFIMSSLVEKYDTDKTLVPVLPNEIY
QQSSVNMVYKERKLKPMRVEYFLDHMKSYFLV
>Mature_271_residues
SKAAEELGINASTVSRKISEIEAYYGVKLLIRSTRALNLTEEGKALYRYFQNVDDVLRRSEDEIMHHQLEPTGILKVVVP
VDLGNLLLQDALVSFSQKYPKVLLDLDFSNRQVDMLEEGIDIWFCIGEVNSKSLISSELLSYRRYLMASKTYLLEYGEIG
SIADLKAPHRQLKSKNPFIYQESDKSVLKQLPVALTVNSGYTIFKACTSGLGLAFIMSSLVEKYDTDKTLVPVLPNEIYQ
QSSVNMVYKERKLKPMRVEYFLDHMKSYFLV

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=273, Percent_Identity=29.3040293040293, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI87081978, Length=275, Percent_Identity=29.8181818181818, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789639, Length=280, Percent_Identity=25.7142857142857, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787128, Length=273, Percent_Identity=24.9084249084249, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI145693193, Length=285, Percent_Identity=28.4210526315789, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1789440, Length=274, Percent_Identity=24.0875912408759, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788706, Length=120, Percent_Identity=32.5, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789173, Length=160, Percent_Identity=30, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788481, Length=238, Percent_Identity=24.7899159663866, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31062; Mature: 30931

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAAEELGINASTVSRKISEIEAYYGVKLLIRSTRALNLTEEGKALYRYFQNVDDVLRR
CCCCHHHHCCCHHHHHHHHHHHHHHHHHHHEEHHHHHCCCCHHHHHHHHHHHHHHHHHHC
SEDEIMHHQLEPTGILKVVVPVDLGNLLLQDALVSFSQKYPKVLLDLDFSNRQVDMLEEG
CHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHCC
IDIWFCIGEVNSKSLISSELLSYRRYLMASKTYLLEYGEIGSIADLKAPHRQLKSKNPFI
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHCCCHHHHHCCCCCCE
YQESDKSVLKQLPVALTVNSGYTIFKACTSGLGLAFIMSSLVEKYDTDKTLVPVLPNEIY
EECCCHHHHHHCCEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCHHHH
QQSSVNMVYKERKLKPMRVEYFLDHMKSYFLV
HHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKAAEELGINASTVSRKISEIEAYYGVKLLIRSTRALNLTEEGKALYRYFQNVDDVLRR
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHEEHHHHHCCCCHHHHHHHHHHHHHHHHHHC
SEDEIMHHQLEPTGILKVVVPVDLGNLLLQDALVSFSQKYPKVLLDLDFSNRQVDMLEEG
CHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHCC
IDIWFCIGEVNSKSLISSELLSYRRYLMASKTYLLEYGEIGSIADLKAPHRQLKSKNPFI
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHCCCHHHHHCCCCCCE
YQESDKSVLKQLPVALTVNSGYTIFKACTSGLGLAFIMSSLVEKYDTDKTLVPVLPNEIY
EECCCHHHHHHCCEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCCCHHHH
QQSSVNMVYKERKLKPMRVEYFLDHMKSYFLV
HHHCCHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]