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The map label for this gene is manP [H]

Identifier: 156977803

GI number: 156977803

Start: 1735088

End: 1735540

Strand: Direct

Name: manP [H]

Synonym: VIBHAR_06591

Alternate gene names: 156977803

Gene position: 1735088-1735540 (Clockwise)

Preceding gene: 156977799

Following gene: 156977804

Centisome position: 78.72

GC content: 39.07

Gene sequence:

>453_bases
ATGAGTCAAAAAATGATTACAGAACTAACAAACGTCAATTTAATTAAAGGCAACCTTCAAGCAAATAATAAAAAAGAAGT
CTTTGAAGAGCTAGCACAGATGCTATTCGAAAATAATCGAGTCAGCAGCAAAGAGGCTTTTTTAACCGACATCGAAGCAC
GTGAAGCATTAAGCGTTACTTCAATGGACGGCATCGCTTACCCACACGCAAAAAGCAAAGCGGTGACAGAGCCTGCGATC
GCTGTTGGCGTAAAGCGCGAAGGCATCGAGTATGGCGACGAAGAGGGAGTCAAACCGACTGTATTCTTCATGATTGCCTC
ACCAGATAACGGTGCCGACCACCATATTTATGTTCTTCAAGAATTATTCGGTAAATTTAGCGAAGAGTTTATTGAAGATA
TTCATAACGCAAAAGACGAAAACCAAATACTAAATATTTTAATTAATTCATAA

Upstream 100 bases:

>100_bases
CACTTAGCTCTCAGTGATACAAAAGTATAGTTATTGGATTTTTTTTACTATTTCAGAAAACCGTAACATTAATTAAATTT
GCCTCATTACTTCAGTACCA

Downstream 100 bases:

>100_bases
GGCGTGAAATTATGAGTACAATCACAGCTCAAGCTAGTAATAATAGCGACTTCAAAAAAATCCTAAGTACCATGAAAGGT
CACCTTTTATTCGGTACTTC

Product: PTS system fructose-specific IIA component

Products: NA

Alternate protein names: EIIBCA-Man; EII-Man; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component; Mannose permease IIC component; PTS system mannose-specific EIIC component; Mannose-specific phosphotransferase enzyme IIA component; PTS system mannose-specific EIIA component [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MSQKMITELTNVNLIKGNLQANNKKEVFEELAQMLFENNRVSSKEAFLTDIEAREALSVTSMDGIAYPHAKSKAVTEPAI
AVGVKREGIEYGDEEGVKPTVFFMIASPDNGADHHIYVLQELFGKFSEEFIEDIHNAKDENQILNILINS

Sequences:

>Translated_150_residues
MSQKMITELTNVNLIKGNLQANNKKEVFEELAQMLFENNRVSSKEAFLTDIEAREALSVTSMDGIAYPHAKSKAVTEPAI
AVGVKREGIEYGDEEGVKPTVFFMIASPDNGADHHIYVLQELFGKFSEEFIEDIHNAKDENQILNILINS
>Mature_149_residues
SQKMITELTNVNLIKGNLQANNKKEVFEELAQMLFENNRVSSKEAFLTDIEAREALSVTSMDGIAYPHAKSKAVTEPAIA
VGVKREGIEYGDEEGVKPTVFFMIASPDNGADHHIYVLQELFGKFSEEFIEDIHNAKDENQILNILINS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1762

COG function: function code GT; Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1786951, Length=146, Percent_Identity=27.3972602739726, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 16774; Mature: 16643

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQKMITELTNVNLIKGNLQANNKKEVFEELAQMLFENNRVSSKEAFLTDIEAREALSVT
CCCHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
SMDGIAYPHAKSKAVTEPAIAVGVKREGIEYGDEEGVKPTVFFMIASPDNGADHHIYVLQ
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHH
ELFGKFSEEFIEDIHNAKDENQILNILINS
HHHHHHHHHHHHHHHCCCCCHHEEEEEECC
>Mature Secondary Structure 
SQKMITELTNVNLIKGNLQANNKKEVFEELAQMLFENNRVSSKEAFLTDIEAREALSVT
CCHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
SMDGIAYPHAKSKAVTEPAIAVGVKREGIEYGDEEGVKPTVFFMIASPDNGADHHIYVLQ
CCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHH
ELFGKFSEEFIEDIHNAKDENQILNILINS
HHHHHHHHHHHHHHHCCCCCHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]