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The map label for this gene is grxB [H]

Identifier: 156977709

GI number: 156977709

Start: 1649989

End: 1650618

Strand: Direct

Name: grxB [H]

Synonym: VIBHAR_06497

Alternate gene names: 156977709

Gene position: 1649989-1650618 (Clockwise)

Preceding gene: 156977708

Following gene: 156977710

Centisome position: 74.86

GC content: 45.56

Gene sequence:

>630_bases
ATGAAACTCTACATTTACGAACATTGCCCATTCAGTGCTCGCGTCCGCTACGTTGCTGGCATGCTGAATATCCAACTCGA
CGTCATCAATATTGCTTATGACGATGACAAAACCACAACAGACCTGATTGGAACCAAACAAGTACCACTTCTTATTAAAG
ACAACGGTGAAGCGATGGCAGAAAGCCTAGATATCATCGCTTACTTCCTTGAACTGGCTACATCAAGTGAAACAAGCCAA
CCATCTCAACAAGCGCTGGATTGGCAAAAAATCGCTTTTCTTCCGCTGCAAAAAGTGGGTTACCCACGTTGGTCAAACAT
CGATTTACCAGAGTTTGCCACTCAGTCTGCACAGCAAGCTTGGCGCGCAAAAAAGGAAACTGACGCACTCAATTTTGATG
CACTCCTGCAGGACACTCCAAACATTGCCAAAGAGGTCGAAGCGCTCATTGAACGTGTGAAAAGTGTGTTGAATCTCGAC
TCTTATCAGCATGTGGCTTTGGTAGACGAAGCGATCCTATTTTCTATTTTGCGCGGGTTCTTCAGTGCCGCAGAAATCCA
ATGGGACAACACCGTGAAAGATTGGATGGAATCGGTAAGCAGCAAAACCCAAGTGCCACTGCTTAAGTAA

Upstream 100 bases:

>100_bases
AGCTCCGAGCTTCAACAACTAATTTCATCCCTACTGGTAGCCCTGACTTAACGTCTCCCGAACAAGCGGGGCTACCCAAT
TAAATCACTAGGAAAACACT

Downstream 100 bases:

>100_bases
GGAGCCGATAATGAGCAAACTATTTGAACCAGCACAGCTAAAACAACTGGATCTACAAAACCGCGTAGTCATGGCACCAA
TGACCCGAGCGCGCACCAGC

Product: glutaredoxin 2

Products: NA

Alternate protein names: Grx2 [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MKLYIYEHCPFSARVRYVAGMLNIQLDVINIAYDDDKTTTDLIGTKQVPLLIKDNGEAMAESLDIIAYFLELATSSETSQ
PSQQALDWQKIAFLPLQKVGYPRWSNIDLPEFATQSAQQAWRAKKETDALNFDALLQDTPNIAKEVEALIERVKSVLNLD
SYQHVALVDEAILFSILRGFFSAAEIQWDNTVKDWMESVSSKTQVPLLK

Sequences:

>Translated_209_residues
MKLYIYEHCPFSARVRYVAGMLNIQLDVINIAYDDDKTTTDLIGTKQVPLLIKDNGEAMAESLDIIAYFLELATSSETSQ
PSQQALDWQKIAFLPLQKVGYPRWSNIDLPEFATQSAQQAWRAKKETDALNFDALLQDTPNIAKEVEALIERVKSVLNLD
SYQHVALVDEAILFSILRGFFSAAEIQWDNTVKDWMESVSSKTQVPLLK
>Mature_209_residues
MKLYIYEHCPFSARVRYVAGMLNIQLDVINIAYDDDKTTTDLIGTKQVPLLIKDNGEAMAESLDIIAYFLELATSSETSQ
PSQQALDWQKIAFLPLQKVGYPRWSNIDLPEFATQSAQQAWRAKKETDALNFDALLQDTPNIAKEVEALIERVKSVLNLD
SYQHVALVDEAILFSILRGFFSAAEIQWDNTVKDWMESVSSKTQVPLLK

Specific function: Involved in reducing some disulfides in a coupled system with glutathione reductase. Does not act as hydrogen donor for ribonucleotide reductase [H]

COG id: COG2999

COG function: function code O; Glutaredoxin 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787303, Length=210, Percent_Identity=31.4285714285714, Blast_Score=107, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR007494
- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR011901
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF04399 Glutaredoxin2_C [H]

EC number: NA

Molecular weight: Translated: 23676; Mature: 23676

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYIYEHCPFSARVRYVAGMLNIQLDVINIAYDDDKTTTDLIGTKQVPLLIKDNGEAMA
CEEEEEECCCHHHHHHHHHHHHEEEEEEEEEEECCCCCHHHHCCCCCCCEEEECCCHHHH
ESLDIIAYFLELATSSETSQPSQQALDWQKIAFLPLQKVGYPRWSNIDLPEFATQSAQQA
HHHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
WRAKKETDALNFDALLQDTPNIAKEVEALIERVKSVLNLDSYQHVALVDEAILFSILRGF
HHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FSAAEIQWDNTVKDWMESVSSKTQVPLLK
HHHHHCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKLYIYEHCPFSARVRYVAGMLNIQLDVINIAYDDDKTTTDLIGTKQVPLLIKDNGEAMA
CEEEEEECCCHHHHHHHHHHHHEEEEEEEEEEECCCCCHHHHCCCCCCCEEEECCCHHHH
ESLDIIAYFLELATSSETSQPSQQALDWQKIAFLPLQKVGYPRWSNIDLPEFATQSAQQA
HHHHHHHHHHHHHCCCCCCCCHHHHHCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
WRAKKETDALNFDALLQDTPNIAKEVEALIERVKSVLNLDSYQHVALVDEAILFSILRGF
HHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
FSAAEIQWDNTVKDWMESVSSKTQVPLLK
HHHHHCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]