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The map label for this gene is frpC [H]

Identifier: 156977657

GI number: 156977657

Start: 1598099

End: 1600681

Strand: Reverse

Name: frpC [H]

Synonym: VIBHAR_06445

Alternate gene names: 156977657

Gene position: 1600681-1598099 (Counterclockwise)

Preceding gene: 156977658

Following gene: 156977656

Centisome position: 72.63

GC content: 56.79

Gene sequence:

>2583_bases
GTGTTTGGTGAGGGCATCGTCCGTGACGAGTTGAGTCTGCGCCGTGAAGGGAACCATCTGGTCATCATGGTAGGTGGGCC
GGACTCGGGTGACTCGATCACCATTGAAGAAGGGTACGTCAACAGTCAGCATCAAATCGAAGAGATTGTGTTGTCGGATG
GCAGTACGGTTTCGCCTCAGTCGTTGCCAATCTTAAGCAGCGCCGAAGCGGATGAGCTGAGAGGTGGGTACTTTGCGGAT
GTGATTGATGGCCGCGAAGGCGATGACCGCCTCTATGGTGAAGGGGGCGACGACACGTTAGAAGGCGGTCAAGGAGATGA
TGTGCTCGATGGGGGCGCAGGCAATGACACGTTGAACGCGGGGGCTGGCAATGACACCGTCACGGCAGGCGCAGGTAATG
ATGTGGTTGCAGGCGGTCTCGGTAACGATACGTTGCATGGCGGCACGGGCAATGACCAAGTGTCCGGCGGTGAGGGCGAC
GATCACCTGACGGTCGCTTACAGTGGCAGTAATACCTTAGACGGTGGCGCGGGTGATGACGTTCTGACGGTCGAAACACC
GACGAGCTCAGGTCGTTACAGTAGCTACTATAAAACAGCCAACAATGCCCGTAACACCTTAATCGGTGGGGCGGGCAATG
ACCGCCTAGTGGGCGGCCTCGGGGCGGAGCGCTACGAGTTCAATCGCGGGGATGGTCAGGACACCATCCGTGACAGAGAC
GTGTACGGCAGCAGTGTTGACCAAATTGTGTTTGGTGAGGGCATCGTCCGTGACGAGTTGAGTCTGCGCCGTGAAGGGAA
CCATCTGGTCATCATGATAGGTGGGCCGGACTCAGGTGACTCGATCACCATTGAAGAAGGGTACGTCAACAGTCAGCATC
AAATCGAAGAGATTGTGTTGTCGGATGGCAGTACGGTTTCGCCTCAGTCGTTGCCAATCTTAAGCAGCGCCGAAGCGGAT
GAGCTGAGAGGTGGGTACTTTGCGGATGTGATTGATGGCCGCGAAGGCGATGACCGCCTCTATGGTGAAGGGGGCGACGA
CACGTTAGAAGGCGGTCAAGGAGATGATGTGCTCGATGGGGGCGCAGGCAATGACACGTTGAACGCGGGGGCTGGCAATG
ACACCGTCACGGCAGGCGCAGGTAATGATGTGGTTGCAGGCGGTCTCGGTAACGATACGTTGCATGGCGGCACGGGCAAC
GACCAAGTGTCCGGCGGTGAGGGCGACGATCACCTGACGGTCGCTTACAGTGGCAGTAATACCTTAGACGGTGGCGCGGG
TGATGACGTTCTGACGGTCGAAACACCGACGAGCTCAGGTCGTTACAGTAGCTACTATAAAACAGCCAATAATGCCCGTA
ACACCTTAATCGGTGGGGCGGGCAATGACCGCCTAGTGGGCGGCCTCGGGGCGGAGCGCTACGAGTTCAATCGCGGGGAT
GGTCAGGACACCATCCGTGACAGAGACGTGTACGGCAGCAGTGTTGACCAAATTGTGTTCGGTGAGGGCATCGTCCGTGA
CGAGTTGAGTCTGCGCCGTGAAGGGAACCATCTGGTCATCATGATAGGTGGGCCGGACTCAGGTGACTCGATCACCATTG
AAGAAGGGTACGTCAACAGTCAGCATCAAATCGAAGAGATTGTGTTGTCGGATGGCAGTACGGTTTCGCCTCAGTCGTTG
CCAATCTTAAGCAGCGCCGAAGCGGATGAGCTGAGAGGTGGGTACTTTGCGGATGTGATTGATGGCCGCGAAGGCGATGA
CCGCCTCTATGGTGAAGGGGGCGACGACACGTTAGAAGGCGGTCAAGGAGATGATGTGCTCGATGGGGGCGCAGGCAATG
ACACGTTGAACGCGGGGGCTGGCAATGACACCGTCACGGCAGGCGCAGGTAATGATGTGGTTGCAGGCGGTCTCGGTAAC
GATACGTTGCATGGCGGCACGGGCAATGACCAAGTGTCCGGCGGTGAGGGCGACGATCACCTGACGGTCGCTTACAGTGG
CAGTAATACCTTAGACGGTGGCGCGGGTGATGACGTTCTGACGGTCGAAACACCGACGAGCTCAGGTCGTTACAGTAGCT
ACTATAAAACAGCCAATAATGCCCGTAACACCTTAATCGGTGGGGCGGGCAATGACCGCCTAGTGGGCGGCCTCGGGGCG
GAGCGCTACGAGTTCAATCGCGGGGATGGTCAGGACACCATCCGTGACAGAGACGTGTACGGCAGCAGTGTTGACCAAAT
TGTGTTTGGTGAGGGCATCGTCCGTGACGAGTTGAGTCTGCGCCGTGAAGGGAACCATCTGGTCATCATGATAGGTGGGC
CGGACTCGGGTGACTCGATCACCATTGAAGAAGGGTACGTCAACAGTCAGTATCAAATCGAAGAGATTGTGTTGTCGGAT
GGCAGTACTGTTTCGCCGTTTGACCTCCCAGACTATGTGGAGCCGGTCATTGAGACGGACCTACTCGTCCAAGCGATGAG
TGCGTTTGATGCGCAAGAAAACGTGGCAAATAACGCTGTTATTGACAGTGTTACCTCCTCAATGTCGCCCAACGTTGTCG
TCAGTGGACGAAGCCCGTTGTAA

Upstream 100 bases:

>100_bases
TAGTGGGCGGCCTCGGGGCGGAGCGCTACGAGTTCAATCGCGGGGATGGTCAGGACACCATCGTGACAGAGACGTGTACG
GCAGCAGTGTTGACCAAATT

Downstream 100 bases:

>100_bases
AGACAAGGCCTTCATCTCTCGATGACGAAATACGATACTTTGCATGCACCGCATGCAGAGTATCGAGTCCAATTTCACGC
CCCCTTGTTTATGAACAAAT

Product: bifunctional hemolysin-adenylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 860; Mature: 860

Protein sequence:

>860_residues
MFGEGIVRDELSLRREGNHLVIMVGGPDSGDSITIEEGYVNSQHQIEEIVLSDGSTVSPQSLPILSSAEADELRGGYFAD
VIDGREGDDRLYGEGGDDTLEGGQGDDVLDGGAGNDTLNAGAGNDTVTAGAGNDVVAGGLGNDTLHGGTGNDQVSGGEGD
DHLTVAYSGSNTLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGAERYEFNRGDGQDTIRDRD
VYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNSQHQIEEIVLSDGSTVSPQSLPILSSAEAD
ELRGGYFADVIDGREGDDRLYGEGGDDTLEGGQGDDVLDGGAGNDTLNAGAGNDTVTAGAGNDVVAGGLGNDTLHGGTGN
DQVSGGEGDDHLTVAYSGSNTLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGAERYEFNRGD
GQDTIRDRDVYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNSQHQIEEIVLSDGSTVSPQSL
PILSSAEADELRGGYFADVIDGREGDDRLYGEGGDDTLEGGQGDDVLDGGAGNDTLNAGAGNDTVTAGAGNDVVAGGLGN
DTLHGGTGNDQVSGGEGDDHLTVAYSGSNTLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGA
ERYEFNRGDGQDTIRDRDVYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNSQYQIEEIVLSD
GSTVSPFDLPDYVEPVIETDLLVQAMSAFDAQENVANNAVIDSVTSSMSPNVVVSGRSPL

Sequences:

>Translated_860_residues
MFGEGIVRDELSLRREGNHLVIMVGGPDSGDSITIEEGYVNSQHQIEEIVLSDGSTVSPQSLPILSSAEADELRGGYFAD
VIDGREGDDRLYGEGGDDTLEGGQGDDVLDGGAGNDTLNAGAGNDTVTAGAGNDVVAGGLGNDTLHGGTGNDQVSGGEGD
DHLTVAYSGSNTLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGAERYEFNRGDGQDTIRDRD
VYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNSQHQIEEIVLSDGSTVSPQSLPILSSAEAD
ELRGGYFADVIDGREGDDRLYGEGGDDTLEGGQGDDVLDGGAGNDTLNAGAGNDTVTAGAGNDVVAGGLGNDTLHGGTGN
DQVSGGEGDDHLTVAYSGSNTLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGAERYEFNRGD
GQDTIRDRDVYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNSQHQIEEIVLSDGSTVSPQSL
PILSSAEADELRGGYFADVIDGREGDDRLYGEGGDDTLEGGQGDDVLDGGAGNDTLNAGAGNDTVTAGAGNDVVAGGLGN
DTLHGGTGNDQVSGGEGDDHLTVAYSGSNTLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGA
ERYEFNRGDGQDTIRDRDVYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNSQYQIEEIVLSD
GSTVSPFDLPDYVEPVIETDLLVQAMSAFDAQENVANNAVIDSVTSSMSPNVVVSGRSPL
>Mature_860_residues
MFGEGIVRDELSLRREGNHLVIMVGGPDSGDSITIEEGYVNSQHQIEEIVLSDGSTVSPQSLPILSSAEADELRGGYFAD
VIDGREGDDRLYGEGGDDTLEGGQGDDVLDGGAGNDTLNAGAGNDTVTAGAGNDVVAGGLGNDTLHGGTGNDQVSGGEGD
DHLTVAYSGSNTLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGAERYEFNRGDGQDTIRDRD
VYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNSQHQIEEIVLSDGSTVSPQSLPILSSAEAD
ELRGGYFADVIDGREGDDRLYGEGGDDTLEGGQGDDVLDGGAGNDTLNAGAGNDTVTAGAGNDVVAGGLGNDTLHGGTGN
DQVSGGEGDDHLTVAYSGSNTLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGAERYEFNRGD
GQDTIRDRDVYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNSQHQIEEIVLSDGSTVSPQSL
PILSSAEADELRGGYFADVIDGREGDDRLYGEGGDDTLEGGQGDDVLDGGAGNDTLNAGAGNDTVTAGAGNDVVAGGLGN
DTLHGGTGNDQVSGGEGDDHLTVAYSGSNTLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGA
ERYEFNRGDGQDTIRDRDVYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNSQYQIEEIVLSD
GSTVSPFDLPDYVEPVIETDLLVQAMSAFDAQENVANNAVIDSVTSSMSPNVVVSGRSPL

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 22 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 88690; Mature: 88690

Theoretical pI: Translated: 3.76; Mature: 3.76

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGEGIVRDELSLRREGNHLVIMVGGPDSGDSITIEEGYVNSQHQIEEIVLSDGSTVSPQ
CCCCCCCHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHEECCCCCCCCC
SLPILSSAEADELRGGYFADVIDGREGDDRLYGEGGDDTLEGGQGDDVLDGGAGNDTLNA
CCCEECCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GAGNDTVTAGAGNDVVAGGLGNDTLHGGTGNDQVSGGEGDDHLTVAYSGSNTLDGGAGDD
CCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
VLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGAERYEFNRGDGQDTIRDRD
EEEEECCCCCCCCCHHHHCCCCCCCEEEECCCCCCEEECCCCCEEECCCCCCCCCCCCCC
VYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNSQHQIEEIVL
CCCCCCCEEEECCCEEHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHEE
SDGSTVSPQSLPILSSAEADELRGGYFADVIDGREGDDRLYGEGGDDTLEGGQGDDVLDG
CCCCCCCCCCCCEECCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GAGNDTLNAGAGNDTVTAGAGNDVVAGGLGNDTLHGGTGNDQVSGGEGDDHLTVAYSGSN
CCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
TLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGAERYEFNRGD
CCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCEEEECCCCCCEEECCCCCEEECCCCC
GQDTIRDRDVYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNS
CCCCCCCCCCCCCCCCEEEECCCEEHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCC
QHQIEEIVLSDGSTVSPQSLPILSSAEADELRGGYFADVIDGREGDDRLYGEGGDDTLEG
HHHHHHHEECCCCCCCCCCCCEECCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCC
GQGDDVLDGGAGNDTLNAGAGNDTVTAGAGNDVVAGGLGNDTLHGGTGNDQVSGGEGDDH
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCE
LTVAYSGSNTLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGA
EEEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCEEEECCCCCCEEECCCC
ERYEFNRGDGQDTIRDRDVYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSI
CEEECCCCCCCCCCCCCCCCCCCCCEEEECCCEEHHHHHHHCCCCEEEEEECCCCCCCEE
TIEEGYVNSQYQIEEIVLSDGSTVSPFDLPDYVEPVIETDLLVQAMSAFDAQENVANNAV
EEECCCCCCCEEEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHH
IDSVTSSMSPNVVVSGRSPL
HHHHHHCCCCCEEEECCCCC
>Mature Secondary Structure
MFGEGIVRDELSLRREGNHLVIMVGGPDSGDSITIEEGYVNSQHQIEEIVLSDGSTVSPQ
CCCCCCCHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHEECCCCCCCCC
SLPILSSAEADELRGGYFADVIDGREGDDRLYGEGGDDTLEGGQGDDVLDGGAGNDTLNA
CCCEECCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GAGNDTVTAGAGNDVVAGGLGNDTLHGGTGNDQVSGGEGDDHLTVAYSGSNTLDGGAGDD
CCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCC
VLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGAERYEFNRGDGQDTIRDRD
EEEEECCCCCCCCCHHHHCCCCCCCEEEECCCCCCEEECCCCCEEECCCCCCCCCCCCCC
VYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNSQHQIEEIVL
CCCCCCCEEEECCCEEHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCHHHHHHHEE
SDGSTVSPQSLPILSSAEADELRGGYFADVIDGREGDDRLYGEGGDDTLEGGQGDDVLDG
CCCCCCCCCCCCEECCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GAGNDTLNAGAGNDTVTAGAGNDVVAGGLGNDTLHGGTGNDQVSGGEGDDHLTVAYSGSN
CCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCC
TLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGAERYEFNRGD
CCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCEEEECCCCCCEEECCCCCEEECCCCC
GQDTIRDRDVYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSITIEEGYVNS
CCCCCCCCCCCCCCCCEEEECCCEEHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCC
QHQIEEIVLSDGSTVSPQSLPILSSAEADELRGGYFADVIDGREGDDRLYGEGGDDTLEG
HHHHHHHEECCCCCCCCCCCCEECCCCHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCC
GQGDDVLDGGAGNDTLNAGAGNDTVTAGAGNDVVAGGLGNDTLHGGTGNDQVSGGEGDDH
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCE
LTVAYSGSNTLDGGAGDDVLTVETPTSSGRYSSYYKTANNARNTLIGGAGNDRLVGGLGA
EEEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHCCCCCCCEEEECCCCCCEEECCCC
ERYEFNRGDGQDTIRDRDVYGSSVDQIVFGEGIVRDELSLRREGNHLVIMIGGPDSGDSI
CEEECCCCCCCCCCCCCCCCCCCCCEEEECCCEEHHHHHHHCCCCEEEEEECCCCCCCEE
TIEEGYVNSQYQIEEIVLSDGSTVSPFDLPDYVEPVIETDLLVQAMSAFDAQENVANNAV
EEECCCCCCCEEEEEEEECCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHH
IDSVTSSMSPNVVVSGRSPL
HHHHHHCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]