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The map label for this gene is mutT [C]

Identifier: 156977584

GI number: 156977584

Start: 1545433

End: 1545831

Strand: Reverse

Name: mutT [C]

Synonym: VIBHAR_06372

Alternate gene names: 156977584

Gene position: 1545831-1545433 (Counterclockwise)

Preceding gene: 156977585

Following gene: 156977580

Centisome position: 70.14

GC content: 46.62

Gene sequence:

>399_bases
ATGCACAAGTCTGCAGGTATCATTATTAAAGACGGCGCGTTGTTAGTGCTGCGATCAAAAGGCAAAGACACCTTCTATGC
GCCGGGCGGAAAACTAGATAATGGCGAAACACCAGAGCAAGCGTTATGTCGCGAACTGCAAGAAGAAGTAAGCATCGTCG
TTGCGGAAGATGCCTTAACGTTGTTTGGTCGCTTTGAGGCGCCTGCACACGATAAAGCCGGCATTACTTTGGTTATGGAT
GTGTTCTTCGTAAATGATTATTCGGGCGAGGTGGTTGCCAGTAACGAAATTGAAGAATGCCAGTGGGTAGATTCTTCAAA
CGTGGATGACATCGCGATAAGCACAATTTTCCGCAATGAGGTCTTCCCACGCTTGGTTGAGCAAGGATTAGTAGAATAA

Upstream 100 bases:

>100_bases
GAAGTTGTCGGCACCGCTAAGAAGCATGCCAAGGTTAACGGCCACTACATCAATGAAGTCATGATCGAGAAATTTCTCTA
ACGCTTAGAAGGAAAGCAAG

Downstream 100 bases:

>100_bases
CGCTAAATCTCGGCCAGAATAAAAACGCCCACAATGCCGATCATACTTTAAGCTTTCCACATGGTTGGTTAGCACAATCA
CTTGTTGGTGAGCTGACGCC

Product: hypothetical protein

Products: 8-Oxo-Dgmp; Pyrophosphate. [C]

Alternate protein names: MutT/Nudix Family Protein; NUDIX Family Hydrolase; MutT Family NTP Pyrophosphatase; Phosphatase; Nudix Family Protein MutT Subfamily; MutT/NUDIX Family Protein; Phosphohydrolase; ADP-Ribose Pyrophosphatase; NTP Pyrophosphohydrolase; Lysine Decarboxylase; MutT/Nudix Family Hydrolase; MutT/Nudix Family Phosphohydrolase; Hydrolase Nudix Family; Nudix Hydrolase; Nudix Superfamily Hydrolase; Conserved Protein YcfB; MutT-Family Protein; MutT Family Protein

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MHKSAGIIIKDGALLVLRSKGKDTFYAPGGKLDNGETPEQALCRELQEEVSIVVAEDALTLFGRFEAPAHDKAGITLVMD
VFFVNDYSGEVVASNEIEECQWVDSSNVDDIAISTIFRNEVFPRLVEQGLVE

Sequences:

>Translated_132_residues
MHKSAGIIIKDGALLVLRSKGKDTFYAPGGKLDNGETPEQALCRELQEEVSIVVAEDALTLFGRFEAPAHDKAGITLVMD
VFFVNDYSGEVVASNEIEECQWVDSSNVDDIAISTIFRNEVFPRLVEQGLVE
>Mature_132_residues
MHKSAGIIIKDGALLVLRSKGKDTFYAPGGKLDNGETPEQALCRELQEEVSIVVAEDALTLFGRFEAPAHDKAGITLVMD
VFFVNDYSGEVVASNEIEECQWVDSSNVDDIAISTIFRNEVFPRLVEQGLVE

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 14489; Mature: 14489

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKSAGIIIKDGALLVLRSKGKDTFYAPGGKLDNGETPEQALCRELQEEVSIVVAEDALT
CCCCCCEEEECCEEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCEE
LFGRFEAPAHDKAGITLVMDVFFVNDYSGEVVASNEIEECQWVDSSNVDDIAISTIFRNE
EHCCCCCCCCCCCCEEEEEEEEEEECCCCCEEECCCCCHHEECCCCCCCHHHHHHHHHHH
VFPRLVEQGLVE
HHHHHHHHCCCC
>Mature Secondary Structure
MHKSAGIIIKDGALLVLRSKGKDTFYAPGGKLDNGETPEQALCRELQEEVSIVVAEDALT
CCCCCCEEEECCEEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHEEEEECCCEE
LFGRFEAPAHDKAGITLVMDVFFVNDYSGEVVASNEIEECQWVDSSNVDDIAISTIFRNE
EHCCCCCCCCCCCCEEEEEEEEEEECCCCCEEECCCCCHHEECCCCCCCHHHHHHHHHHH
VFPRLVEQGLVE
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 8-Oxo-Dgtp; H2O [C]

Specific reaction: 8-Oxo-Dgtp + H2O = 8-Oxo-Dgmp + Pyrophosphate. [C]

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA