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The map label for this gene is sglT [H]

Identifier: 156977562

GI number: 156977562

Start: 1517953

End: 1519473

Strand: Reverse

Name: sglT [H]

Synonym: VIBHAR_06350

Alternate gene names: 156977562

Gene position: 1519473-1517953 (Counterclockwise)

Preceding gene: 156977564

Following gene: 156977561

Centisome position: 68.94

GC content: 48.13

Gene sequence:

>1521_bases
ATGAACAGTACACTTTTTCTTACCGGCTTCGGTGCGTATGTCTTATTTTTAATTTGGTTGGGATGGTTTGTCTCTCGCAA
TCAAAAATCAGGTGAAGACTTTCTACTCGGTGGTCGAGGCTTACCTCTGTTCCTCGTATTAGGTACCACGGTAGCAACCA
TGGTTAGCACTGGCTCTAGTATGGGCGCGGTTGGCTTTGGTTATTCAAACGGTTGGGCTGGTGCGCTTTACGGCATTGGT
GGCGCAATTGGTATCTTGTTATTGGCACTGTGGTTTGCGCCAGTTCGTAAACTCAACTTTATGACTATGAGTGAAGAGCT
CGCATACTACGTAGGTGCAAACCGCATCGTGAAGAACGTGGTTGGTCTGCTTATCTTTATCGCTTCTATTGGCTGGTTGG
GCGCACACATCCTTGGTGGTGGTATGTACCTCGCGTGGATTGCCGATATTGAGCTGAGCACTGCCAAGATGATCATCGCA
GCAGCGTTTACCATTTACGTTGTTATTGGCGGCTACACTGCGGTGGTTTGGACGGACACCATTCAAGCTATCATCTTATT
CATTGGCTTCATCCTAATGGCGGTACTGTCTGTGCAACACATTGGCGGCTTGGATAACCTCTACTCTGCCATGGACCCAG
AAGCGGTTAGCTTCCTTGCGATTGATAAGCTTGGTTTAATCCCAGCAGTTTCTCTTGCTGTTGTGATTGGTGTGGGTGTA
CTTGCAACGCCTTCATTCCGCCAACGTATCTACTCAGGCAAAGATGTATCAACCATCCGCGGTTCATTCGTAGCGTCTGG
TGTGTTGTACTTGTTCTTCTCCATCATCCCTGCAGTCATTGGTATGGCGGCGCATGCGATTGACCCCGAGCTGAATAATG
CAAACTTTGCTTTCCCATACATCGCGGCAACGGTATTGCCAGTAGGTGTTGGTCTTATCGTTCTGATTGCAGGTCTATCA
GCAACCATGTCGAGTGCGAGTTCCGATGCGATTGCGGGCGTTTCTATCCTACTGCGTGATGTTTACGTCATGTTCACCGG
TCGCGTGCCAAACAAAGAATCTATGTTGAATTACTCTCGCTTGGCTTTGGTTGTGGTGATCGGTTGTGCATTGCTGTTCG
CTCTAACTTCGAACGACATCATCGGCTACATCACTAAGATGATCTCGACAGTTATGTCTGGCATGTTCGTGTGCGGTATG
TTGGGTCGCTTCTGGAAGCGTTACAACTGGCAAGGTGCATTGGCAACATTGGCAGGTGCGTCTATCGCTTCATTTTCAGT
AATGATGAGCCCTGACCTAACCGCTTTCTGGGGCAACCCAGTGATTCCATCTTGCTTGTTTGCTCTAACTGCTGGTGTGG
CAGTGAGCCTAGTGACTCCAGCTAACCAAGTGTCACCAGAAATGGCACGAGCAATCCTAGATGATGAGCGTGCTCTGATG
GAAATGGAACTGTCTGACGATGGTGTTCTAGAAGAAGATGCTTCATTAAAAAACCGTACAACAGCAAATCAAAACGCTTA
A

Upstream 100 bases:

>100_bases
ACTATAAAAATAAAATTAGATAATTTCTGGAATAAAATCTAATACTTGCTGCTGGAATTATATCAATCTGAAAGATGGAT
TTTGATATGAGAGGTGTTCA

Downstream 100 bases:

>100_bases
CAGCAAAGAGTTTCGGCTCGAACAGAAACTCGCTCATTAGCTCCTGACAAACTGGTGGCTCCCCCGAGCCACCATTCTAA
ATTTATCCAAAGTAGGTGAA

Product: hypothetical protein

Products: Na (I) [Cytoplasm]; pantothenate [Cytoplasm] [C]

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MNSTLFLTGFGAYVLFLIWLGWFVSRNQKSGEDFLLGGRGLPLFLVLGTTVATMVSTGSSMGAVGFGYSNGWAGALYGIG
GAIGILLLALWFAPVRKLNFMTMSEELAYYVGANRIVKNVVGLLIFIASIGWLGAHILGGGMYLAWIADIELSTAKMIIA
AAFTIYVVIGGYTAVVWTDTIQAIILFIGFILMAVLSVQHIGGLDNLYSAMDPEAVSFLAIDKLGLIPAVSLAVVIGVGV
LATPSFRQRIYSGKDVSTIRGSFVASGVLYLFFSIIPAVIGMAAHAIDPELNNANFAFPYIAATVLPVGVGLIVLIAGLS
ATMSSASSDAIAGVSILLRDVYVMFTGRVPNKESMLNYSRLALVVVIGCALLFALTSNDIIGYITKMISTVMSGMFVCGM
LGRFWKRYNWQGALATLAGASIASFSVMMSPDLTAFWGNPVIPSCLFALTAGVAVSLVTPANQVSPEMARAILDDERALM
EMELSDDGVLEEDASLKNRTTANQNA

Sequences:

>Translated_506_residues
MNSTLFLTGFGAYVLFLIWLGWFVSRNQKSGEDFLLGGRGLPLFLVLGTTVATMVSTGSSMGAVGFGYSNGWAGALYGIG
GAIGILLLALWFAPVRKLNFMTMSEELAYYVGANRIVKNVVGLLIFIASIGWLGAHILGGGMYLAWIADIELSTAKMIIA
AAFTIYVVIGGYTAVVWTDTIQAIILFIGFILMAVLSVQHIGGLDNLYSAMDPEAVSFLAIDKLGLIPAVSLAVVIGVGV
LATPSFRQRIYSGKDVSTIRGSFVASGVLYLFFSIIPAVIGMAAHAIDPELNNANFAFPYIAATVLPVGVGLIVLIAGLS
ATMSSASSDAIAGVSILLRDVYVMFTGRVPNKESMLNYSRLALVVVIGCALLFALTSNDIIGYITKMISTVMSGMFVCGM
LGRFWKRYNWQGALATLAGASIASFSVMMSPDLTAFWGNPVIPSCLFALTAGVAVSLVTPANQVSPEMARAILDDERALM
EMELSDDGVLEEDASLKNRTTANQNA
>Mature_506_residues
MNSTLFLTGFGAYVLFLIWLGWFVSRNQKSGEDFLLGGRGLPLFLVLGTTVATMVSTGSSMGAVGFGYSNGWAGALYGIG
GAIGILLLALWFAPVRKLNFMTMSEELAYYVGANRIVKNVVGLLIFIASIGWLGAHILGGGMYLAWIADIELSTAKMIIA
AAFTIYVVIGGYTAVVWTDTIQAIILFIGFILMAVLSVQHIGGLDNLYSAMDPEAVSFLAIDKLGLIPAVSLAVVIGVGV
LATPSFRQRIYSGKDVSTIRGSFVASGVLYLFFSIIPAVIGMAAHAIDPELNNANFAFPYIAATVLPVGVGLIVLIAGLS
ATMSSASSDAIAGVSILLRDVYVMFTGRVPNKESMLNYSRLALVVVIGCALLFALTSNDIIGYITKMISTVMSGMFVCGM
LGRFWKRYNWQGALATLAGASIASFSVMMSPDLTAFWGNPVIPSCLFALTAGVAVSLVTPANQVSPEMARAILDDERALM
EMELSDDGVLEEDASLKNRTTANQNA

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG0591

COG function: function code ER; Na+/proline symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI14140236, Length=435, Percent_Identity=25.5172413793103, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI4507031, Length=441, Percent_Identity=23.3560090702948, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI110835708, Length=457, Percent_Identity=21.4442013129103, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI17941285, Length=448, Percent_Identity=22.7678571428571, Blast_Score=76, Evalue=9e-14,
Organism=Homo sapiens, GI206597483, Length=383, Percent_Identity=25.8485639686684, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI4507033, Length=503, Percent_Identity=22.2664015904573, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87082237, Length=453, Percent_Identity=22.9580573951435, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787251, Length=382, Percent_Identity=24.869109947644, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790503, Length=425, Percent_Identity=22.3529411764706, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17539284, Length=407, Percent_Identity=25.0614250614251, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648033, Length=401, Percent_Identity=26.6832917705736, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21356865, Length=401, Percent_Identity=26.6832917705736, Blast_Score=78, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 53625; Mature: 53625

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTLFLTGFGAYVLFLIWLGWFVSRNQKSGEDFLLGGRGLPLFLVLGTTVATMVSTGSS
CCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCC
MGAVGFGYSNGWAGALYGIGGAIGILLLALWFAPVRKLNFMTMSEELAYYVGANRIVKNV
CCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLLIFIASIGWLGAHILGGGMYLAWIADIELSTAKMIIAAAFTIYVVIGGYTAVVWTDT
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEEHHH
IQAIILFIGFILMAVLSVQHIGGLDNLYSAMDPEAVSFLAIDKLGLIPAVSLAVVIGVGV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATPSFRQRIYSGKDVSTIRGSFVASGVLYLFFSIIPAVIGMAAHAIDPELNNANFAFPY
HCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHH
IAATVLPVGVGLIVLIAGLSATMSSASSDAIAGVSILLRDVYVMFTGRVPNKESMLNYSR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LALVVVIGCALLFALTSNDIIGYITKMISTVMSGMFVCGMLGRFWKRYNWQGALATLAGA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
SIASFSVMMSPDLTAFWGNPVIPSCLFALTAGVAVSLVTPANQVSPEMARAILDDERALM
HHHHEEEEECCCCCEECCCCCHHHHHHHHHHHHHEEEECCCHHCCHHHHHHHHCCCHHHH
EMELSDDGVLEEDASLKNRTTANQNA
EEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNSTLFLTGFGAYVLFLIWLGWFVSRNQKSGEDFLLGGRGLPLFLVLGTTVATMVSTGSS
CCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHCCCC
MGAVGFGYSNGWAGALYGIGGAIGILLLALWFAPVRKLNFMTMSEELAYYVGANRIVKNV
CCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLLIFIASIGWLGAHILGGGMYLAWIADIELSTAKMIIAAAFTIYVVIGGYTAVVWTDT
HHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCEEEEEEHHH
IQAIILFIGFILMAVLSVQHIGGLDNLYSAMDPEAVSFLAIDKLGLIPAVSLAVVIGVGV
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATPSFRQRIYSGKDVSTIRGSFVASGVLYLFFSIIPAVIGMAAHAIDPELNNANFAFPY
HCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHH
IAATVLPVGVGLIVLIAGLSATMSSASSDAIAGVSILLRDVYVMFTGRVPNKESMLNYSR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LALVVVIGCALLFALTSNDIIGYITKMISTVMSGMFVCGMLGRFWKRYNWQGALATLAGA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
SIASFSVMMSPDLTAFWGNPVIPSCLFALTAGVAVSLVTPANQVSPEMARAILDDERALM
HHHHEEEEECCCCCEECCCCCHHHHHHHHHHHHHEEEECCCHHCCHHHHHHHHCCCHHHH
EMELSDDGVLEEDASLKNRTTANQNA
EEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; pantothenate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + pantothenate [Periplasm] = Na (I) [Cytoplasm] + pantothenate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]