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The map label for this gene is mdaB [H]

Identifier: 156977549

GI number: 156977549

Start: 1506247

End: 1506831

Strand: Reverse

Name: mdaB [H]

Synonym: VIBHAR_06337

Alternate gene names: 156977549

Gene position: 1506831-1506247 (Counterclockwise)

Preceding gene: 156977553

Following gene: 156977548

Centisome position: 68.37

GC content: 44.96

Gene sequence:

>585_bases
ATGAGCAACGTACTGATCATCAATGCACACGAACCATCACCATATTCAGAAGGTCGTCTAAATGCTTCTCTTGTTGATAA
AGCGCAGACGCTTCTGCAAGCAAAAGACCATGACGTTCGCGTTGTGACAATGCAAGATGAGATCAACGTAGATGAGCAAC
TCGCACACTTTGAATGGGCTGATCGCGTGATCATCCAAAGCCCAATCAACTGGATGTCTGTGCCTTGGTCATTCAAAAAA
TACATGGACGATGTTTTTACTGCGGGTATGGGCGGCGCTCTGTGTGCTTTCGACGGTCGTAGCGCAGAAGAACCAAAGAA
AAACTACGGTACAGGTGGTACGCGAACCAACACTAAGTACATGCTTTCACTGACATTCAACGCACCAAAAGAATCGTTTG
ATGATGAGAACGAATACCTGTTCCAAGGTAAAGGTGTCGATGATTTGATGTTCCACATGCACGCTAACTTCCGCTTCTTT
GGTATGTCAGCACTGCCGACATTCGCTAGCTACGATGTGATGAAGAATGCGGATATCGAAAATGATTTTACACGTTTCGA
AGCGCACATTAACGAAAACTTCTAA

Upstream 100 bases:

>100_bases
AGTTAACTAATTGCATTGTATTTCTAGGTTACCATAATAAACCACATCCGACGCACAATGGTTATCGCGTCATATTGTGA
ACTTATTTAAGGGTAATCCT

Downstream 100 bases:

>100_bases
TCCTTTTAGAAACATAGTGTGAACTGAATGATGAATTGAGATGGACTGCTGCATGCGGTCCATTTTTATTTGTTTGCGGC
GAGGTGACGTTTTTATTACT

Product: modulator of drug activity B

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MSNVLIINAHEPSPYSEGRLNASLVDKAQTLLQAKDHDVRVVTMQDEINVDEQLAHFEWADRVIIQSPINWMSVPWSFKK
YMDDVFTAGMGGALCAFDGRSAEEPKKNYGTGGTRTNTKYMLSLTFNAPKESFDDENEYLFQGKGVDDLMFHMHANFRFF
GMSALPTFASYDVMKNADIENDFTRFEAHINENF

Sequences:

>Translated_194_residues
MSNVLIINAHEPSPYSEGRLNASLVDKAQTLLQAKDHDVRVVTMQDEINVDEQLAHFEWADRVIIQSPINWMSVPWSFKK
YMDDVFTAGMGGALCAFDGRSAEEPKKNYGTGGTRTNTKYMLSLTFNAPKESFDDENEYLFQGKGVDDLMFHMHANFRFF
GMSALPTFASYDVMKNADIENDFTRFEAHINENF
>Mature_193_residues
SNVLIINAHEPSPYSEGRLNASLVDKAQTLLQAKDHDVRVVTMQDEINVDEQLAHFEWADRVIIQSPINWMSVPWSFKKY
MDDVFTAGMGGALCAFDGRSAEEPKKNYGTGGTRTNTKYMLSLTFNAPKESFDDENEYLFQGKGVDDLMFHMHANFRFFG
MSALPTFASYDVMKNADIENDFTRFEAHINENF

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=194, Percent_Identity=43.8144329896907, Blast_Score=164, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 22117; Mature: 21986

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVLIINAHEPSPYSEGRLNASLVDKAQTLLQAKDHDVRVVTMQDEINVDEQLAHFEWA
CCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHH
DRVIIQSPINWMSVPWSFKKYMDDVFTAGMGGALCAFDGRSAEEPKKNYGTGGTRTNTKY
CEEEEECCCCCEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCEE
MLSLTFNAPKESFDDENEYLFQGKGVDDLMFHMHANFRFFGMSALPTFASYDVMKNADIE
EEEEEECCCCCCCCCCCCEEEECCCHHHHHHEEECCEEEEECCCCCCHHHHHHHCCCCCC
NDFTRFEAHINENF
CHHHHHHEEECCCC
>Mature Secondary Structure 
SNVLIINAHEPSPYSEGRLNASLVDKAQTLLQAKDHDVRVVTMQDEINVDEQLAHFEWA
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHH
DRVIIQSPINWMSVPWSFKKYMDDVFTAGMGGALCAFDGRSAEEPKKNYGTGGTRTNTKY
CEEEEECCCCCEECCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCEE
MLSLTFNAPKESFDDENEYLFQGKGVDDLMFHMHANFRFFGMSALPTFASYDVMKNADIE
EEEEEECCCCCCCCCCCCEEEECCCHHHHHHEEECCEEEEECCCCCCHHHHHHHCCCCCC
NDFTRFEAHINENF
CHHHHHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]