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The map label for this gene is erg3 [H]

Identifier: 156977374

GI number: 156977374

Start: 1336407

End: 1337222

Strand: Reverse

Name: erg3 [H]

Synonym: VIBHAR_06161

Alternate gene names: 156977374

Gene position: 1337222-1336407 (Counterclockwise)

Preceding gene: 156977375

Following gene: 156977372

Centisome position: 60.67

GC content: 46.2

Gene sequence:

>816_bases
ATGGAATGGTCACAGATTACAGAGCATCCTGATTTATTGTTGATGTTGCTCGCGCCAATATTCTTTCTTTGTATTGCGGC
AGAATATTGGTTTGGACAGCGGGGTGGTCGATTGCCTGAGAGTGCGCGATATTACTTGCCAGAAGTCGTGTGTAACTTTG
TATTGGCTGGGCTTCATCAAGCGACAGATATCTTAACAGGGCTGTTGATCGCTAAACTGTATTTGTGGTGGTTTGGTTGG
CGCTTGTTTGATATCGAGATGACGGTTTCAACCTTCCTGTTACTCATGGTATTGCAAGATTTCTTCTATTATTGGTTCCA
CCGAGCAAGCCACCGTATCCGTTGGATGTGGGCAGCGCATGTGGTGCACCACAGTTCAGAGCGTATGAACTTCAGTACCG
CATTTCGCCAAAGCCTGATGTACCCACTAGCGGGTATGTGGTTATTCTGGTTGCCACTGGTCATTATTGGATTTGATCCT
AGATGGGTGGTGTTTGTTGTGCTGCTCAACCTTGGTCTGCAATTCTTTGTTCATACTCAGTCGATTCGTTCCCTTGGACC
TTTGGAGTGGGTCTTCAATACACCATCCCACCACCGCGTGCATCATGGCGTGAATCATCAATACATTGATAAAAATTACG
CTGGCGTGCTGATCATCTGGGATCGCATGTTTGGAACATTCGAGCCAGAAGTAGAAACCGTCCGTTATGACATCTCAAAG
CCCGTTAACAGCTTTAATCCTATTACCGTGACGTTCGCGGAATGGAAAGATATGTTCAAAGAGGTGACTCGTCCCAATTT
GTCTTGGCGTCAATGA

Upstream 100 bases:

>100_bases
CTTTTCAGGCTATTTGATTGATGAAAATGGCATTAAACACGAACTCGATGAGGTGATGGGACTCACCGAAGATCATTACG
CGAAATGGTAGGGACGGACT

Downstream 100 bases:

>100_bases
AGGGAAGCGATCGGTTGAGGTCACCATGAAGAAACGCGCTGGTGGCGGGCTGAAAAACGATACGTTCACTACACTTCAGT
TGGAGTAACCCCAAAGATAT

Product: C-5 sterol desaturase

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MEWSQITEHPDLLLMLLAPIFFLCIAAEYWFGQRGGRLPESARYYLPEVVCNFVLAGLHQATDILTGLLIAKLYLWWFGW
RLFDIEMTVSTFLLLMVLQDFFYYWFHRASHRIRWMWAAHVVHHSSERMNFSTAFRQSLMYPLAGMWLFWLPLVIIGFDP
RWVVFVVLLNLGLQFFVHTQSIRSLGPLEWVFNTPSHHRVHHGVNHQYIDKNYAGVLIIWDRMFGTFEPEVETVRYDISK
PVNSFNPITVTFAEWKDMFKEVTRPNLSWRQ

Sequences:

>Translated_271_residues
MEWSQITEHPDLLLMLLAPIFFLCIAAEYWFGQRGGRLPESARYYLPEVVCNFVLAGLHQATDILTGLLIAKLYLWWFGW
RLFDIEMTVSTFLLLMVLQDFFYYWFHRASHRIRWMWAAHVVHHSSERMNFSTAFRQSLMYPLAGMWLFWLPLVIIGFDP
RWVVFVVLLNLGLQFFVHTQSIRSLGPLEWVFNTPSHHRVHHGVNHQYIDKNYAGVLIIWDRMFGTFEPEVETVRYDISK
PVNSFNPITVTFAEWKDMFKEVTRPNLSWRQ
>Mature_271_residues
MEWSQITEHPDLLLMLLAPIFFLCIAAEYWFGQRGGRLPESARYYLPEVVCNFVLAGLHQATDILTGLLIAKLYLWWFGW
RLFDIEMTVSTFLLLMVLQDFFYYWFHRASHRIRWMWAAHVVHHSSERMNFSTAFRQSLMYPLAGMWLFWLPLVIIGFDP
RWVVFVVLLNLGLQFFVHTQSIRSLGPLEWVFNTPSHHRVHHGVNHQYIDKNYAGVLIIWDRMFGTFEPEVETVRYDISK
PVNSFNPITVTFAEWKDMFKEVTRPNLSWRQ

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=154, Percent_Identity=56.4935064935065, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI25144659, Length=194, Percent_Identity=41.2371134020619, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 32309; Mature: 32309

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWSQITEHPDLLLMLLAPIFFLCIAAEYWFGQRGGRLPESARYYLPEVVCNFVLAGLHQ
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ATDILTGLLIAKLYLWWFGWRLFDIEMTVSTFLLLMVLQDFFYYWFHRASHRIRWMWAAH
HHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VVHHSSERMNFSTAFRQSLMYPLAGMWLFWLPLVIIGFDPRWVVFVVLLNLGLQFFVHTQ
HHHHCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
SIRSLGPLEWVFNTPSHHRVHHGVNHQYIDKNYAGVLIIWDRMFGTFEPEVETVRYDISK
HHHHCCCCCEEECCCCCCHHHCCCCCCCCCCCCCEEEEEEEHHCCCCCCCHHHHHHHHHC
PVNSFNPITVTFAEWKDMFKEVTRPNLSWRQ
CCCCCCCEEEEHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEWSQITEHPDLLLMLLAPIFFLCIAAEYWFGQRGGRLPESARYYLPEVVCNFVLAGLHQ
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ATDILTGLLIAKLYLWWFGWRLFDIEMTVSTFLLLMVLQDFFYYWFHRASHRIRWMWAAH
HHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
VVHHSSERMNFSTAFRQSLMYPLAGMWLFWLPLVIIGFDPRWVVFVVLLNLGLQFFVHTQ
HHHHCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
SIRSLGPLEWVFNTPSHHRVHHGVNHQYIDKNYAGVLIIWDRMFGTFEPEVETVRYDISK
HHHHCCCCCEEECCCCCCHHHCCCCCCCCCCCCCEEEEEEEHHCCCCCCCHHHHHHHHHC
PVNSFNPITVTFAEWKDMFKEVTRPNLSWRQ
CCCCCCCEEEEHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]