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The map label for this gene is pknB [H]

Identifier: 156977080

GI number: 156977080

Start: 1053190

End: 1055250

Strand: Reverse

Name: pknB [H]

Synonym: VIBHAR_05865

Alternate gene names: 156977080

Gene position: 1055250-1053190 (Counterclockwise)

Preceding gene: 156977081

Following gene: 156977079

Centisome position: 47.88

GC content: 44.54

Gene sequence:

>2061_bases
ATGTTTCAACCAATATTATTTCATCCTAATAATATTTGTTCGATAAAAGAGTGCAAAGTGTCTGATAAGCAGGGAGCGGC
AAAAGGATATATTGATCAATTGGTTGTCAAAGCCATTGAGAAAAAGAAACATAACGAGCAAAGGTTGGCGAAGAAAAATA
AGCCAAAGCTTGAGTACGTGCTTTTTTCACAATTTGATGTACTAGACACCTTGCCGTCGAAAAATGGTAGAACAACCGTT
TACCATCTCGCCAAAAAAGGCCAACCTGAAAAGCAAATCTGCTGTAAAGTCGTCAATGAGGACGCGCCAGATATTGCCAG
CAAAATGTTGGTCAATGAGGCAAGCAGATTAGAGCTTTCTCAACATCCAAGCGTTGCGGATTTCATTAAAATCGGTAACG
AATTTGAACGTCCATACTTAATGTACGAGTGGATCCAAGGTGAATCACTGGCAGAAAAGATGGAGCGTCATTCCTCTAAA
GGTTTCCGTCACGATCACATTGCTTGGTTAGTTTACCAACTCGCCGGTGCGCTTGAATTCATGCACACTCGAGGTATTTG
TCATCTTGATATCAAACCATCGAATGTCCTGGTTAGCGAGGGCGATTACGTCAAGCTGATTGACTTTGGTGCAGCGCGCT
ATATCGGTGAGGCTGAATCTCATGCCGAAGCGAGTTTAAGTTACGCGTCGCCACTTTATCTAGAGACTGGCACGACCGAA
CCACAAGACGATGTTTATTCACTTGCACTGCTGACGGGCCATTTATTTATTGGTTCTATTTTCGGTGATGCATGGCACAA
GCAATTAAAAGATCGTAAGCGTCCGGCACTGATTCCAAATCATATTTGGAAGCTGCTCAAGCAAGTGATTAATAATCCAA
GAGGGCATGGCTATACCGCTATTTCTTTTGCTCAGCAACTTGCCCGCATTGATACTCAATCTATCGATTCTCAATCGAAT
GCGCCTATTTTTAGTAGTCTGCGTAATGCTGATTTATTGCTGACGCATTGTAAGCCTCAAGACAAAGGCGGTTACGGTCG
TTTTAAAGTGCTTGAAGCAAGCTTGGTATTAAGTGTGATGGCAGTGACAGGCCACTATCTGTACGAGCAAAATCAACCAG
AGTGGAAAACAATCGTAAAATCGGAACCAACGATTTCACAAGCGGGAACGCCGCTGGTTAGCACTATTAAGCCTGCGCAA
ACGGCTTCTTTCTTGGCGCAACCTCCTTGGGCGATTGAACAGGCGCTCAATGATATGGAAAAAGACGTTATATCGACGGC
GCCATATCGTGAAGCGTACCAAGTTCAGCAAACGAAGCTGTCCAAGCTGTACAAAAAGAACCAAGGTGAATTGACGGCTT
ATCAAGCCTTGGCCGATGAGTTACCAAAAACGTTGGTCGATCTGCGTAAAGAGCTAGTCACATTGCGCGAAAAACTTGTC
GATGATGGCGCGCTATTCCCTTATGCAGATAAAACTCTGACTAAAGTGATGGCGGGTTTGAATGTGGCTTCGGTCGACTC
GATGAAAATTTCTGCCATAGCGGGAAGTAAAGAGGAGCAGATTGCCAGCTTGATCCTTGATGGTGAAGTGCAGCTTGCGG
ACAAAGAAATGAAAGCTGCTTGGTTACTAAACCAATCTGAGGCGTATTTCTATAGCCAAGTGTTGCCAAACAAGGTCATG
AAGAACATCAATGACTCTATTGAGCTGCATGCAAAGGATCATTACTACACCAAAGCCATCGAAGAGACGAAAGCGGCGAA
GGCGTACTTTGGTAATACTCCAGAACTAACCAAAAAAGTCAAAGATCTGATTGTCGCTCGTAGCGAATACATCCTATTTA
GCACGGTCACTGAGCAATCCGTCTTTGATAAACAGAAACTGCACGATTCCCTTACCGATCTTGAGCGAAATGCACCTAAG
AAGTTTGGTGAAATCACCGACTTGCTTGAGAGCATGGCAACGGACTCCATCGATAAAAGCCATCAACTTTCTCGTCCTGC
ACGCGGTGCCATAGCGGTTGAACGAGCGTTAAGAGACTACCAAGCAGAGGGGAGAGGCTAA

Upstream 100 bases:

>100_bases
TGATGTAGTGAAAGCGTAAGTCAAAGAGTCTAATAACTTAGTAATAATAACTAAAGTAATAGACTTACTGTTCGTTTTAA
ATACCAGCCTTGAAACAAGG

Downstream 100 bases:

>100_bases
TGTCAGTGATTGATATCGAACGTTTGCTTACGCCAATTTCTGATGCTGCTCCGGTAGGTGAAGACGCGCGCTACGAGTTT
TGCTATGAAATGATGGAATC

Product: serine-threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 686; Mature: 686

Protein sequence:

>686_residues
MFQPILFHPNNICSIKECKVSDKQGAAKGYIDQLVVKAIEKKKHNEQRLAKKNKPKLEYVLFSQFDVLDTLPSKNGRTTV
YHLAKKGQPEKQICCKVVNEDAPDIASKMLVNEASRLELSQHPSVADFIKIGNEFERPYLMYEWIQGESLAEKMERHSSK
GFRHDHIAWLVYQLAGALEFMHTRGICHLDIKPSNVLVSEGDYVKLIDFGAARYIGEAESHAEASLSYASPLYLETGTTE
PQDDVYSLALLTGHLFIGSIFGDAWHKQLKDRKRPALIPNHIWKLLKQVINNPRGHGYTAISFAQQLARIDTQSIDSQSN
APIFSSLRNADLLLTHCKPQDKGGYGRFKVLEASLVLSVMAVTGHYLYEQNQPEWKTIVKSEPTISQAGTPLVSTIKPAQ
TASFLAQPPWAIEQALNDMEKDVISTAPYREAYQVQQTKLSKLYKKNQGELTAYQALADELPKTLVDLRKELVTLREKLV
DDGALFPYADKTLTKVMAGLNVASVDSMKISAIAGSKEEQIASLILDGEVQLADKEMKAAWLLNQSEAYFYSQVLPNKVM
KNINDSIELHAKDHYYTKAIEETKAAKAYFGNTPELTKKVKDLIVARSEYILFSTVTEQSVFDKQKLHDSLTDLERNAPK
KFGEITDLLESMATDSIDKSHQLSRPARGAIAVERALRDYQAEGRG

Sequences:

>Translated_686_residues
MFQPILFHPNNICSIKECKVSDKQGAAKGYIDQLVVKAIEKKKHNEQRLAKKNKPKLEYVLFSQFDVLDTLPSKNGRTTV
YHLAKKGQPEKQICCKVVNEDAPDIASKMLVNEASRLELSQHPSVADFIKIGNEFERPYLMYEWIQGESLAEKMERHSSK
GFRHDHIAWLVYQLAGALEFMHTRGICHLDIKPSNVLVSEGDYVKLIDFGAARYIGEAESHAEASLSYASPLYLETGTTE
PQDDVYSLALLTGHLFIGSIFGDAWHKQLKDRKRPALIPNHIWKLLKQVINNPRGHGYTAISFAQQLARIDTQSIDSQSN
APIFSSLRNADLLLTHCKPQDKGGYGRFKVLEASLVLSVMAVTGHYLYEQNQPEWKTIVKSEPTISQAGTPLVSTIKPAQ
TASFLAQPPWAIEQALNDMEKDVISTAPYREAYQVQQTKLSKLYKKNQGELTAYQALADELPKTLVDLRKELVTLREKLV
DDGALFPYADKTLTKVMAGLNVASVDSMKISAIAGSKEEQIASLILDGEVQLADKEMKAAWLLNQSEAYFYSQVLPNKVM
KNINDSIELHAKDHYYTKAIEETKAAKAYFGNTPELTKKVKDLIVARSEYILFSTVTEQSVFDKQKLHDSLTDLERNAPK
KFGEITDLLESMATDSIDKSHQLSRPARGAIAVERALRDYQAEGRG
>Mature_686_residues
MFQPILFHPNNICSIKECKVSDKQGAAKGYIDQLVVKAIEKKKHNEQRLAKKNKPKLEYVLFSQFDVLDTLPSKNGRTTV
YHLAKKGQPEKQICCKVVNEDAPDIASKMLVNEASRLELSQHPSVADFIKIGNEFERPYLMYEWIQGESLAEKMERHSSK
GFRHDHIAWLVYQLAGALEFMHTRGICHLDIKPSNVLVSEGDYVKLIDFGAARYIGEAESHAEASLSYASPLYLETGTTE
PQDDVYSLALLTGHLFIGSIFGDAWHKQLKDRKRPALIPNHIWKLLKQVINNPRGHGYTAISFAQQLARIDTQSIDSQSN
APIFSSLRNADLLLTHCKPQDKGGYGRFKVLEASLVLSVMAVTGHYLYEQNQPEWKTIVKSEPTISQAGTPLVSTIKPAQ
TASFLAQPPWAIEQALNDMEKDVISTAPYREAYQVQQTKLSKLYKKNQGELTAYQALADELPKTLVDLRKELVTLREKLV
DDGALFPYADKTLTKVMAGLNVASVDSMKISAIAGSKEEQIASLILDGEVQLADKEMKAAWLLNQSEAYFYSQVLPNKVM
KNINDSIELHAKDHYYTKAIEETKAAKAYFGNTPELTKKVKDLIVARSEYILFSTVTEQSVFDKQKLHDSLTDLERNAPK
KFGEITDLLESMATDSIDKSHQLSRPARGAIAVERALRDYQAEGRG

Specific function: Unknown

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI4505569, Length=167, Percent_Identity=26.3473053892216, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI115529463, Length=184, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI4507831, Length=117, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI212642197, Length=178, Percent_Identity=26.4044943820225, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565634, Length=166, Percent_Identity=30.1204819277108, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203047, Length=178, Percent_Identity=26.4044943820225, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323125, Length=239, Percent_Identity=24.2677824267782, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6324557, Length=194, Percent_Identity=28.8659793814433, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325047, Length=143, Percent_Identity=28.6713286713287, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320327, Length=174, Percent_Identity=27.0114942528736, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550904, Length=179, Percent_Identity=31.8435754189944, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550091, Length=179, Percent_Identity=31.8435754189944, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17137774, Length=192, Percent_Identity=23.9583333333333, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI281360507, Length=159, Percent_Identity=32.7044025157233, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI45552175, Length=159, Percent_Identity=32.7044025157233, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24653966, Length=206, Percent_Identity=26.6990291262136, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653972, Length=206, Percent_Identity=26.6990291262136, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24653974, Length=206, Percent_Identity=26.6990291262136, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24653970, Length=206, Percent_Identity=26.6990291262136, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24653968, Length=206, Percent_Identity=26.6990291262136, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR005543
- InterPro:   IPR000719
- InterPro:   IPR017441
- InterPro:   IPR017442
- InterPro:   IPR008271 [H]

Pfam domain/function: PF03793 PASTA; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 77021; Mature: 77021

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS00108 PROTEIN_KINASE_ST ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQPILFHPNNICSIKECKVSDKQGAAKGYIDQLVVKAIEKKKHNEQRLAKKNKPKLEYV
CCCCEEECCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
LFSQFDVLDTLPSKNGRTTVYHLAKKGQPEKQICCKVVNEDAPDIASKMLVNEASRLELS
EHHHHHHHHHCCCCCCCEEEEEEHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHH
QHPSVADFIKIGNEFERPYLMYEWIQGESLAEKMERHSSKGFRHDHIAWLVYQLAGALEF
CCCCHHHHHHHCCHHCCCEEEEHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
MHTRGICHLDIKPSNVLVSEGDYVKLIDFGAARYIGEAESHAEASLSYASPLYLETGTTE
HHHCCEEEEECCCCCEEECCCCEEEEEECCHHHHHCCHHHHHHHHHCCCCCEEEECCCCC
PQDDVYSLALLTGHLFIGSIFGDAWHKQLKDRKRPALIPNHIWKLLKQVINNPRGHGYTA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHH
ISFAQQLARIDTQSIDSQSNAPIFSSLRNADLLLTHCKPQDKGGYGRFKVLEASLVLSVM
HHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
AVTGHYLYEQNQPEWKTIVKSEPTISQAGTPLVSTIKPAQTASFLAQPPWAIEQALNDME
HHHHHHHHCCCCCHHHHHHCCCCCHHHCCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHH
KDVISTAPYREAYQVQQTKLSKLYKKNQGELTAYQALADELPKTLVDLRKELVTLREKLV
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDGALFPYADKTLTKVMAGLNVASVDSMKISAIAGSKEEQIASLILDGEVQLADKEMKAA
CCCCCCCCCHHHHHHHHHCCCEECCCCEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHH
WLLNQSEAYFYSQVLPNKVMKNINDSIELHAKDHYYTKAIEETKAAKAYFGNTPELTKKV
HHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHH
KDLIVARSEYILFSTVTEQSVFDKQKLHDSLTDLERNAPKKFGEITDLLESMATDSIDKS
HHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHH
HQLSRPARGAIAVERALRDYQAEGRG
HHHCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFQPILFHPNNICSIKECKVSDKQGAAKGYIDQLVVKAIEKKKHNEQRLAKKNKPKLEYV
CCCCEEECCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
LFSQFDVLDTLPSKNGRTTVYHLAKKGQPEKQICCKVVNEDAPDIASKMLVNEASRLELS
EHHHHHHHHHCCCCCCCEEEEEEHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHH
QHPSVADFIKIGNEFERPYLMYEWIQGESLAEKMERHSSKGFRHDHIAWLVYQLAGALEF
CCCCHHHHHHHCCHHCCCEEEEHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
MHTRGICHLDIKPSNVLVSEGDYVKLIDFGAARYIGEAESHAEASLSYASPLYLETGTTE
HHHCCEEEEECCCCCEEECCCCEEEEEECCHHHHHCCHHHHHHHHHCCCCCEEEECCCCC
PQDDVYSLALLTGHLFIGSIFGDAWHKQLKDRKRPALIPNHIWKLLKQVINNPRGHGYTA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCHH
ISFAQQLARIDTQSIDSQSNAPIFSSLRNADLLLTHCKPQDKGGYGRFKVLEASLVLSVM
HHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
AVTGHYLYEQNQPEWKTIVKSEPTISQAGTPLVSTIKPAQTASFLAQPPWAIEQALNDME
HHHHHHHHCCCCCHHHHHHCCCCCHHHCCCCHHHHCCCHHHHHHHCCCCHHHHHHHHHHH
KDVISTAPYREAYQVQQTKLSKLYKKNQGELTAYQALADELPKTLVDLRKELVTLREKLV
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DDGALFPYADKTLTKVMAGLNVASVDSMKISAIAGSKEEQIASLILDGEVQLADKEMKAA
CCCCCCCCCHHHHHHHHHCCCEECCCCEEEEEECCCCHHHHHHHHCCCCEEEHHHHHHHH
WLLNQSEAYFYSQVLPNKVMKNINDSIELHAKDHYYTKAIEETKAAKAYFGNTPELTKKV
HHCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHH
KDLIVARSEYILFSTVTEQSVFDKQKLHDSLTDLERNAPKKFGEITDLLESMATDSIDKS
HHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHH
HQLSRPARGAIAVERALRDYQAEGRG
HHHCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]