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The map label for this gene is cirA [H]

Identifier: 156977062

GI number: 156977062

Start: 1031179

End: 1033335

Strand: Reverse

Name: cirA [H]

Synonym: VIBHAR_05847

Alternate gene names: 156977062

Gene position: 1033335-1031179 (Counterclockwise)

Preceding gene: 156977063

Following gene: 156977061

Centisome position: 46.88

GC content: 46.04

Gene sequence:

>2157_bases
ATGCGTTTGTCGTTAAACCTCGTGATTGCATCCACGTTTGGAGCTGTTGCTCCTGCCTCTGCTAACTATGATCTAGATTC
TTTACTAGAAATGCCATTGTGTTCCTTGGCTGAAACCAAGGTTGTTTCGGCCACTCGAACCTCGCAATCCCTTGCAGATA
CGCCCGCGTCTGTATATGTCATTACCGCAAAAGAGATTAAACGCTCTGGTGCGCGCTCGGTTGCTGATGCGCTATCTTTG
GCACCCGGTCTTCATGTCGCAAAATACTCCAACTACGATTGGGGAGTGACGGTGCGTGGCAATAACGAAACCTTGAACAA
TAAAATGTTGGTCATGGTCGATGGCCGTAGCGTTTTTAACCCAATGTCTTCAGGTGTCGATTGGGATTTGATCCCGGTCA
GCATGGAGAATATATCTCAGATCGAAATCGTACTTGGCCCGGTCGGCACAGTATGGGGTGGCAATGCCGTAACAGGTATT
ATTAATGTCATCACAAAAGAAGCGGATGGTGTAGCAAAAGGGAAGGTATCTGCTAGCTTCGGAAACTACGATTACCGTGA
ATATCAGCTCTATCATGCTGGCTCTGTTGGTAAATACGCAAACTACAGTCTTTACGGTGAGTTTGTTGATCATATGCCGT
GGACAAGTGATGATGCGCGTGTAAAGCCATTCCAGCATTTCAATGTGTATACCGAGCGCTTTGGTGGTCGTTTGGATTAT
CAGAAGCATGAACATACATTGAGCGTACAAGCGGGTGGTATTCGTTCGCGTGAAGATGACAACTGGGGTAATTTCCAACC
GCACTTTATCATGTCAGGTGCAGAGCCAATGCGTACTCACGAAGCGGAAATGACGATGCAAGAGTACTTCGTTGGTGGCC
ATCATGTGTTTGACCGCAGCAATGGCGACAGTTGGGAAAACGAGCTGTGGTTGACTTACAGCTCTAACGACAGTACCCAC
GCGAATGCACAGTTTCTTAGAACCGATTTAGATTCTCACTATACTTTTTCGGACTTATGGGGAACAGAGCTCACCGTCGG
TGGCAATATCCGATTGATTGATGAAAAGTTTGGCACGTTCTCCACATATGAATTGGTGACGATGCCTTACCTTCGCGTAG
CAGAAGATCCAGACTTCCTAAACCAGTCTTACGGTTTGTACATGAACTGGAACATTCCTGTTATGGACAAAACCAAACTA
ACGCTGGGCAATCGCTGGCAGTACAACAACCTGACTCATGATATCGATCCGCAGCCACAAGTTCGCTTGAGTTATGAACT
CGCAAACAACCAAAGAATTTGGGCTGGGTGGGGTAAAGCGATTGTGACGCCTTCACGTCTTGAGCTAAGCACCTACATGC
GTGAAAACCAGTACATGCAGAACGTTATGTTTAGCGATAACAATTACTACGATTACTACTACAGCACGATACTCAAAGGC
AATGAGGATCTCGATGTCGAATCGGTTTCTACCTATGAACTTGGGTATCGTTTTTGGGATGAGCACAGGCTGCAATTCAG
CATCGGGGGCTTTTATACCCGACACGAGAACATTCGCGTTTATAAAACAGAGTCAGCGTCGCAAATCATCATTGGTGAAG
GTTCATCGCCTGGTAGGGTTGGCACGGTGGTAGAGCAGTACACTTCTCAGTTGGTGGATCCAATTTGGAGTGAGAGTTTT
GGTGGTGAAATCGCTGTGAAATGGCAACCCCGTGATGATCTCCAAATTAATGCCAACTACAGCTATAAGCGAATTGTTGG
TCACTGCGAAGGTGCCATCTGCTCAAGCAATGATGCTGTAAAACGAATGATTGAAAATGAGCCAAACCATTTTGTGAATG
CCCAAGTAATGTGGGACATCACGCCTCAATGGTGGGTAAGTGTCAGTGGGCAATATGTTTCTGAATCGGAACTGCATGAA
GATTATGAATCGGCATTGCATCCTGTTTCTGTAGCAAATAAAGACTACAGCTGGCCTGAAGTTGTGTCTTTTGATGCCTC
TTTGAGTTGGCAATACAACGACTGCATGCCTGAGATTACAGCCTCAGTAGAGAATCTAGGAGCGAATCAAAGCAAAGAGT
TTCCCAATAATTACAACTCTTTTGCCAATGGGACTCAGTACTGGCTGACCTTAGATTGGAATTACGCCGGATGGTAA

Upstream 100 bases:

>100_bases
CAAATGGTACACTGTACTCATATAGATACACTGTAATTTAACGTTTGAACCTCTTCCCCCAAATACCATTTTTTGCGTTC
AAACGTTGAGAAATACCCCT

Downstream 100 bases:

>100_bases
AGCGTTTTGAGAAAACATCCGCCTTCAAGTATGGGCTCGCTCTTTGGGCCTTACTGAGTGCGACGTTGGCTTTTGCTCAG
TATGACGATGCGGATTTAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 718; Mature: 718

Protein sequence:

>718_residues
MRLSLNLVIASTFGAVAPASANYDLDSLLEMPLCSLAETKVVSATRTSQSLADTPASVYVITAKEIKRSGARSVADALSL
APGLHVAKYSNYDWGVTVRGNNETLNNKMLVMVDGRSVFNPMSSGVDWDLIPVSMENISQIEIVLGPVGTVWGGNAVTGI
INVITKEADGVAKGKVSASFGNYDYREYQLYHAGSVGKYANYSLYGEFVDHMPWTSDDARVKPFQHFNVYTERFGGRLDY
QKHEHTLSVQAGGIRSREDDNWGNFQPHFIMSGAEPMRTHEAEMTMQEYFVGGHHVFDRSNGDSWENELWLTYSSNDSTH
ANAQFLRTDLDSHYTFSDLWGTELTVGGNIRLIDEKFGTFSTYELVTMPYLRVAEDPDFLNQSYGLYMNWNIPVMDKTKL
TLGNRWQYNNLTHDIDPQPQVRLSYELANNQRIWAGWGKAIVTPSRLELSTYMRENQYMQNVMFSDNNYYDYYYSTILKG
NEDLDVESVSTYELGYRFWDEHRLQFSIGGFYTRHENIRVYKTESASQIIIGEGSSPGRVGTVVEQYTSQLVDPIWSESF
GGEIAVKWQPRDDLQINANYSYKRIVGHCEGAICSSNDAVKRMIENEPNHFVNAQVMWDITPQWWVSVSGQYVSESELHE
DYESALHPVSVANKDYSWPEVVSFDASLSWQYNDCMPEITASVENLGANQSKEFPNNYNSFANGTQYWLTLDWNYAGW

Sequences:

>Translated_718_residues
MRLSLNLVIASTFGAVAPASANYDLDSLLEMPLCSLAETKVVSATRTSQSLADTPASVYVITAKEIKRSGARSVADALSL
APGLHVAKYSNYDWGVTVRGNNETLNNKMLVMVDGRSVFNPMSSGVDWDLIPVSMENISQIEIVLGPVGTVWGGNAVTGI
INVITKEADGVAKGKVSASFGNYDYREYQLYHAGSVGKYANYSLYGEFVDHMPWTSDDARVKPFQHFNVYTERFGGRLDY
QKHEHTLSVQAGGIRSREDDNWGNFQPHFIMSGAEPMRTHEAEMTMQEYFVGGHHVFDRSNGDSWENELWLTYSSNDSTH
ANAQFLRTDLDSHYTFSDLWGTELTVGGNIRLIDEKFGTFSTYELVTMPYLRVAEDPDFLNQSYGLYMNWNIPVMDKTKL
TLGNRWQYNNLTHDIDPQPQVRLSYELANNQRIWAGWGKAIVTPSRLELSTYMRENQYMQNVMFSDNNYYDYYYSTILKG
NEDLDVESVSTYELGYRFWDEHRLQFSIGGFYTRHENIRVYKTESASQIIIGEGSSPGRVGTVVEQYTSQLVDPIWSESF
GGEIAVKWQPRDDLQINANYSYKRIVGHCEGAICSSNDAVKRMIENEPNHFVNAQVMWDITPQWWVSVSGQYVSESELHE
DYESALHPVSVANKDYSWPEVVSFDASLSWQYNDCMPEITASVENLGANQSKEFPNNYNSFANGTQYWLTLDWNYAGW
>Mature_718_residues
MRLSLNLVIASTFGAVAPASANYDLDSLLEMPLCSLAETKVVSATRTSQSLADTPASVYVITAKEIKRSGARSVADALSL
APGLHVAKYSNYDWGVTVRGNNETLNNKMLVMVDGRSVFNPMSSGVDWDLIPVSMENISQIEIVLGPVGTVWGGNAVTGI
INVITKEADGVAKGKVSASFGNYDYREYQLYHAGSVGKYANYSLYGEFVDHMPWTSDDARVKPFQHFNVYTERFGGRLDY
QKHEHTLSVQAGGIRSREDDNWGNFQPHFIMSGAEPMRTHEAEMTMQEYFVGGHHVFDRSNGDSWENELWLTYSSNDSTH
ANAQFLRTDLDSHYTFSDLWGTELTVGGNIRLIDEKFGTFSTYELVTMPYLRVAEDPDFLNQSYGLYMNWNIPVMDKTKL
TLGNRWQYNNLTHDIDPQPQVRLSYELANNQRIWAGWGKAIVTPSRLELSTYMRENQYMQNVMFSDNNYYDYYYSTILKG
NEDLDVESVSTYELGYRFWDEHRLQFSIGGFYTRHENIRVYKTESASQIIIGEGSSPGRVGTVVEQYTSQLVDPIWSESF
GGEIAVKWQPRDDLQINANYSYKRIVGHCEGAICSSNDAVKRMIENEPNHFVNAQVMWDITPQWWVSVSGQYVSESELHE
DYESALHPVSVANKDYSWPEVVSFDASLSWQYNDCMPEITASVENLGANQSKEFPNNYNSFANGTQYWLTLDWNYAGW

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=133, Percent_Identity=33.8345864661654, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1790405, Length=175, Percent_Identity=26.8571428571429, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81510; Mature: 81510

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSLNLVIASTFGAVAPASANYDLDSLLEMPLCSLAETKVVSATRTSQSLADTPASVYV
CEEEEEEEEEECCCCCCCCCCCCCHHHHHHCCHHHHHCCCEEEHHCCCHHHHCCCCEEEE
ITAKEIKRSGARSVADALSLAPGLHVAKYSNYDWGVTVRGNNETLNNKMLVMVDGRSVFN
EEHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCEEEEEECCCHHHC
PMSSGVDWDLIPVSMENISQIEIVLGPVGTVWGGNAVTGIINVITKEADGVAKGKVSASF
HHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECC
GNYDYREYQLYHAGSVGKYANYSLYGEFVDHMPWTSDDARVKPFQHFNVYTERFGGRLDY
CCCCCEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
QKHEHTLSVQAGGIRSREDDNWGNFQPHFIMSGAEPMRTHEAEMTMQEYFVGGHHVFDRS
CCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECC
NGDSWENELWLTYSSNDSTHANAQFLRTDLDSHYTFSDLWGTELTVGGNIRLIDEKFGTF
CCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCEEHHCCCCEEEECCCEEEEECCCCCC
STYELVTMPYLRVAEDPDFLNQSYGLYMNWNIPVMDKTKLTLGNRWQYNNLTHDIDPQPQ
EEEEEEECCCEEECCCHHHHCCCCCEEEECCCCEECCCEEEECCEEEECCCCCCCCCCCC
VRLSYELANNQRIWAGWGKAIVTPSRLELSTYMRENQYMQNVMFSDNNYYDYYYSTILKG
EEEEEEECCCCEEEEECCCEEECCCHHHHHHHHHHHHHHHHHEECCCCEEEEEEEEEECC
NEDLDVESVSTYELGYRFWDEHRLQFSIGGFYTRHENIRVYKTESASQIIIGEGSSPGRV
CCCCCCCCEEEEECCEEEECCCEEEEEECCEEEECCCEEEEEECCCCEEEEECCCCCCHH
GTVVEQYTSQLVDPIWSESFGGEIAVKWQPRDDLQINANYSYKRIVGHCEGAICSSNDAV
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCHHHHHHHCCCCEECCCHHH
KRMIENEPNHFVNAQVMWDITPQWWVSVSGQYVSESELHEDYESALHPVSVANKDYSWPE
HHHHHCCCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCCCCC
VVSFDASLSWQYNDCMPEITASVENLGANQSKEFPNNYNSFANGTQYWLTLDWNYAGW
EEEECCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure
MRLSLNLVIASTFGAVAPASANYDLDSLLEMPLCSLAETKVVSATRTSQSLADTPASVYV
CEEEEEEEEEECCCCCCCCCCCCCHHHHHHCCHHHHHCCCEEEHHCCCHHHHCCCCEEEE
ITAKEIKRSGARSVADALSLAPGLHVAKYSNYDWGVTVRGNNETLNNKMLVMVDGRSVFN
EEHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCEEEEEECCCHHHC
PMSSGVDWDLIPVSMENISQIEIVLGPVGTVWGGNAVTGIINVITKEADGVAKGKVSASF
HHHCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECC
GNYDYREYQLYHAGSVGKYANYSLYGEFVDHMPWTSDDARVKPFQHFNVYTERFGGRLDY
CCCCCEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
QKHEHTLSVQAGGIRSREDDNWGNFQPHFIMSGAEPMRTHEAEMTMQEYFVGGHHVFDRS
CCCCEEEEEEECCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCEEEEECC
NGDSWENELWLTYSSNDSTHANAQFLRTDLDSHYTFSDLWGTELTVGGNIRLIDEKFGTF
CCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCCEEHHCCCCEEEECCCEEEEECCCCCC
STYELVTMPYLRVAEDPDFLNQSYGLYMNWNIPVMDKTKLTLGNRWQYNNLTHDIDPQPQ
EEEEEEECCCEEECCCHHHHCCCCCEEEECCCCEECCCEEEECCEEEECCCCCCCCCCCC
VRLSYELANNQRIWAGWGKAIVTPSRLELSTYMRENQYMQNVMFSDNNYYDYYYSTILKG
EEEEEEECCCCEEEEECCCEEECCCHHHHHHHHHHHHHHHHHEECCCCEEEEEEEEEECC
NEDLDVESVSTYELGYRFWDEHRLQFSIGGFYTRHENIRVYKTESASQIIIGEGSSPGRV
CCCCCCCCEEEEECCEEEECCCEEEEEECCEEEECCCEEEEEECCCCEEEEECCCCCCHH
GTVVEQYTSQLVDPIWSESFGGEIAVKWQPRDDLQINANYSYKRIVGHCEGAICSSNDAV
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCHHHHHHHCCCCEECCCHHH
KRMIENEPNHFVNAQVMWDITPQWWVSVSGQYVSESELHEDYESALHPVSVANKDYSWPE
HHHHHCCCCCEEEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCEEECCCCCCCCC
VVSFDASLSWQYNDCMPEITASVENLGANQSKEFPNNYNSFANGTQYWLTLDWNYAGW
EEEECCEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]