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The map label for this gene is ykoW [H]

Identifier: 156977060

GI number: 156977060

Start: 1028733

End: 1030649

Strand: Reverse

Name: ykoW [H]

Synonym: VIBHAR_05845

Alternate gene names: 156977060

Gene position: 1030649-1028733 (Counterclockwise)

Preceding gene: 156977061

Following gene: 156977059

Centisome position: 46.76

GC content: 44.81

Gene sequence:

>1917_bases
ATGATTCGTTCTCGTCTTGCTCGCTTACCTCTGCGTCATAAGATGATGTTGCCGACTTGGTTAATGATCACGTTGATTGT
TATTGGCTTGGGGACTTTAGCTATTCAATATTTGGTGTTGGCGCAAGAAGCTGCACTTGATCGAAGAACCAATATTCTTG
GACAGGGCGTTGCCAATACGCTTCAAGCGGCGTTGATGTTTGATGATGCATACGCAGCAAAAGAACAATTGGTTAATTTG
AGCTTTGACCCTGACGTTATTTCTGCCCTTGTTATCAATCAAAATGACCAAACCATGGCTTCGATTGAGGATTTGCCTGT
TGGTTGTGAATGGCAGAAACGAACATTGGAGTGTACTCACCTAAGTGTTGTGATGCGTCATTATGATGTTGTGTTAGGTG
ATGAAAAGCTGGGTGCATTAGAAGTTTGGGTGTCACTGGAGAACCTACTCATCAATGAACGAAAGATGTGGCTCTCATTA
GCCGTGATCGTTTTGTTACTTTCCATGTGTGCGTGGGCATTAGCTAAATTGCTGCATTCATTGATCTCATTGCCTTTGTT
GTCACTGCATCGTTCGGTTGAACACATGAGTCGGGTTGGCGTGATTCGAAAAACACTCCCGGTTTATCACCAAGATGAAG
TTGGTAAGCTCACGGCATGCTTTAATGAGATGACCATGAGCTTGGCTGAGCGTGAGTCTCAAGTAGCACAGGTTTTGAAG
CGAGTAGAGGACAAAAACCGCTATATTCACAGCGCATTAGATGCGATGCAGCGTTGCGTGCTCGTTGTTTCTTCTTACCA
TAAAGTCACGTACTTCAACCCGGTCGCCTCGAAAGAGATGAAAGGGGTCGACGTCAATTCGGATGTTCGTACGTTGCTCA
CGAGTTGGTTTGAGCCTGTATCTAAAATCGAACGAATCATGTTTGCGATAGATACGCACACCACGGTAAAGGGAATAGAG
GTTCGTAGCTTAGATAAAACCAAGCGTTATTTGATTTCTTGCAATCCGATGGATACAGAAAAAAGCAGCTTGATCCAGTT
GCAGGACATCACAGAGCAAACCTTGTCTGAGCAGCGCCGTAAGTTACTTGATTTGATGTTTGACCAAAACCAAGATGCCA
TTTTAGTGTTAAACCGAGCACTGAGTATCCAAACCCAAAACCATGCTGCGACACAATGGTTTGGTGAGGTGGGGGCGTTA
AGGACGTTAGAGCTTTTATCACCGTTTGAAGTGACTAAGGCAATTAAGCTTCGATTGCTCAAAACAGGACACTACAAGAC
GCACGTTGAGCTGAAAAACCAACAAGGACGGGTTATGCCTTGTGAGTTGAAAGTGCGAGTGTTGAAGAGTGAAACTGGCA
GAGCGGAAGCGTTCGTGGTTTCATTTACGGATTTAACCATAGATATCGAGCTCAAGCGTCTGAATTATCAAGCGAATCAC
GACCCATTAACGGGTTTGGCTAACCGCTCAAAAGCGATGCGTCGTTTACAAGAGAAGCACGATTTGGGGACATCACAACA
TATTCTGTTTGTTGATTTGGATGGCTTTAAAGCCGTAAACGACCAATATGGGCACGCGATTGGTGACCAACTATTGAAAG
TTGTCGCACAACGTTTGATGAGTTGTGTGGCAAGGCGAGACTTGGTGTCACGTTTGGCGGGTGATGAGTTTTTGATTGCG
GTTCGTGAAGCGACAAGCTGTGAGCCGATTGCTCAAAGGATCATCGAGAGTCTATCCAAACCGTTTCTCTTTGGTGATAT
AACGTGTGGCATCTCTGCAAGCATCGGCGTGAGTTATTGGCCACGCGATGAAAATACTTCCCTTGAAGAAAAAATCAACG
AGGCGGACATGGCGATGTATTTCGCCAAAAAAGAAGGAAAGAACCAGTTTCGTTCAGGTTTAGAAACGGTTTACTAA

Upstream 100 bases:

>100_bases
TTCGCCCTATGGTTTCGCGTGGCCATGTTGCACCTACCGGTGTTCAACTTAGAGCGCAATTACTCAGTATTTCGATCCTA
GCGGAAGACGAGGGGGAGCC

Downstream 100 bases:

>100_bases
GCGCGTTAAACGAAGGGCCATTTCTACAGAAGTGGCCTTTTTTGTTCGTATTACACGACACGAACCACTAAATATTCCAT
ATAACCCTGTTTAAAGGTTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MIRSRLARLPLRHKMMLPTWLMITLIVIGLGTLAIQYLVLAQEAALDRRTNILGQGVANTLQAALMFDDAYAAKEQLVNL
SFDPDVISALVINQNDQTMASIEDLPVGCEWQKRTLECTHLSVVMRHYDVVLGDEKLGALEVWVSLENLLINERKMWLSL
AVIVLLLSMCAWALAKLLHSLISLPLLSLHRSVEHMSRVGVIRKTLPVYHQDEVGKLTACFNEMTMSLAERESQVAQVLK
RVEDKNRYIHSALDAMQRCVLVVSSYHKVTYFNPVASKEMKGVDVNSDVRTLLTSWFEPVSKIERIMFAIDTHTTVKGIE
VRSLDKTKRYLISCNPMDTEKSSLIQLQDITEQTLSEQRRKLLDLMFDQNQDAILVLNRALSIQTQNHAATQWFGEVGAL
RTLELLSPFEVTKAIKLRLLKTGHYKTHVELKNQQGRVMPCELKVRVLKSETGRAEAFVVSFTDLTIDIELKRLNYQANH
DPLTGLANRSKAMRRLQEKHDLGTSQHILFVDLDGFKAVNDQYGHAIGDQLLKVVAQRLMSCVARRDLVSRLAGDEFLIA
VREATSCEPIAQRIIESLSKPFLFGDITCGISASIGVSYWPRDENTSLEEKINEADMAMYFAKKEGKNQFRSGLETVY

Sequences:

>Translated_638_residues
MIRSRLARLPLRHKMMLPTWLMITLIVIGLGTLAIQYLVLAQEAALDRRTNILGQGVANTLQAALMFDDAYAAKEQLVNL
SFDPDVISALVINQNDQTMASIEDLPVGCEWQKRTLECTHLSVVMRHYDVVLGDEKLGALEVWVSLENLLINERKMWLSL
AVIVLLLSMCAWALAKLLHSLISLPLLSLHRSVEHMSRVGVIRKTLPVYHQDEVGKLTACFNEMTMSLAERESQVAQVLK
RVEDKNRYIHSALDAMQRCVLVVSSYHKVTYFNPVASKEMKGVDVNSDVRTLLTSWFEPVSKIERIMFAIDTHTTVKGIE
VRSLDKTKRYLISCNPMDTEKSSLIQLQDITEQTLSEQRRKLLDLMFDQNQDAILVLNRALSIQTQNHAATQWFGEVGAL
RTLELLSPFEVTKAIKLRLLKTGHYKTHVELKNQQGRVMPCELKVRVLKSETGRAEAFVVSFTDLTIDIELKRLNYQANH
DPLTGLANRSKAMRRLQEKHDLGTSQHILFVDLDGFKAVNDQYGHAIGDQLLKVVAQRLMSCVARRDLVSRLAGDEFLIA
VREATSCEPIAQRIIESLSKPFLFGDITCGISASIGVSYWPRDENTSLEEKINEADMAMYFAKKEGKNQFRSGLETVY
>Mature_638_residues
MIRSRLARLPLRHKMMLPTWLMITLIVIGLGTLAIQYLVLAQEAALDRRTNILGQGVANTLQAALMFDDAYAAKEQLVNL
SFDPDVISALVINQNDQTMASIEDLPVGCEWQKRTLECTHLSVVMRHYDVVLGDEKLGALEVWVSLENLLINERKMWLSL
AVIVLLLSMCAWALAKLLHSLISLPLLSLHRSVEHMSRVGVIRKTLPVYHQDEVGKLTACFNEMTMSLAERESQVAQVLK
RVEDKNRYIHSALDAMQRCVLVVSSYHKVTYFNPVASKEMKGVDVNSDVRTLLTSWFEPVSKIERIMFAIDTHTTVKGIE
VRSLDKTKRYLISCNPMDTEKSSLIQLQDITEQTLSEQRRKLLDLMFDQNQDAILVLNRALSIQTQNHAATQWFGEVGAL
RTLELLSPFEVTKAIKLRLLKTGHYKTHVELKNQQGRVMPCELKVRVLKSETGRAEAFVVSFTDLTIDIELKRLNYQANH
DPLTGLANRSKAMRRLQEKHDLGTSQHILFVDLDGFKAVNDQYGHAIGDQLLKVVAQRLMSCVARRDLVSRLAGDEFLIA
VREATSCEPIAQRIIESLSKPFLFGDITCGISASIGVSYWPRDENTSLEEKINEADMAMYFAKKEGKNQFRSGLETVY

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=195, Percent_Identity=36.9230769230769, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1788381, Length=175, Percent_Identity=37.7142857142857, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1787802, Length=191, Percent_Identity=32.4607329842932, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1788956, Length=195, Percent_Identity=32.8205128205128, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081881, Length=168, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082007, Length=164, Percent_Identity=34.7560975609756, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1787816, Length=261, Percent_Identity=28.3524904214559, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=32.5, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI87081977, Length=156, Percent_Identity=33.974358974359, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787262, Length=161, Percent_Identity=31.6770186335404, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786584, Length=166, Percent_Identity=28.9156626506024, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788085, Length=183, Percent_Identity=30.0546448087432, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 72223; Mature: 72223

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS50885 HAMP ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRSRLARLPLRHKMMLPTWLMITLIVIGLGTLAIQYLVLAQEAALDRRTNILGQGVANT
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQAALMFDDAYAAKEQLVNLSFDPDVISALVINQNDQTMASIEDLPVGCEWQKRTLECTH
HHHHHHHHHHHHHHHHHCCCCCCHHHHEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHH
LSVVMRHYDVVLGDEKLGALEVWVSLENLLINERKMWLSLAVIVLLLSMCAWALAKLLHS
HHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISLPLLSLHRSVEHMSRVGVIRKTLPVYHQDEVGKLTACFNEMTMSLAERESQVAQVLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVEDKNRYIHSALDAMQRCVLVVSSYHKVTYFNPVASKEMKGVDVNSDVRTLLTSWFEPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHH
SKIERIMFAIDTHTTVKGIEVRSLDKTKRYLISCNPMDTEKSSLIQLQDITEQTLSEQRR
HHHHHHHHHCCCCCEEECEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
KLLDLMFDQNQDAILVLNRALSIQTQNHAATQWFGEVGALRTLELLSPFEVTKAIKLRLL
HHHHHHHCCCCCEEEEEEHHHEEEECCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
KTGHYKTHVELKNQQGRVMPCELKVRVLKSETGRAEAFVVSFTDLTIDIELKRLNYQANH
CCCCEEEEEEEECCCCCEEEHHHEEEEECCCCCCCEEEEEEEEEEEEEEEEEEECCCCCC
DPLTGLANRSKAMRRLQEKHDLGTSQHILFVDLDGFKAVNDQYGHAIGDQLLKVVAQRLM
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHCHHHHHHHHHHHHHHHHHHHH
SCVARRDLVSRLAGDEFLIAVREATSCEPIAQRIIESLSKPFLFGDITCGISASIGVSYW
HHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEC
PRDENTSLEEKINEADMAMYFAKKEGKNQFRSGLETVY
CCCCCCCHHHHHCHHHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MIRSRLARLPLRHKMMLPTWLMITLIVIGLGTLAIQYLVLAQEAALDRRTNILGQGVANT
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQAALMFDDAYAAKEQLVNLSFDPDVISALVINQNDQTMASIEDLPVGCEWQKRTLECTH
HHHHHHHHHHHHHHHHHCCCCCCHHHHEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHH
LSVVMRHYDVVLGDEKLGALEVWVSLENLLINERKMWLSLAVIVLLLSMCAWALAKLLHS
HHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISLPLLSLHRSVEHMSRVGVIRKTLPVYHQDEVGKLTACFNEMTMSLAERESQVAQVLK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVEDKNRYIHSALDAMQRCVLVVSSYHKVTYFNPVASKEMKGVDVNSDVRTLLTSWFEPV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHH
SKIERIMFAIDTHTTVKGIEVRSLDKTKRYLISCNPMDTEKSSLIQLQDITEQTLSEQRR
HHHHHHHHHCCCCCEEECEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
KLLDLMFDQNQDAILVLNRALSIQTQNHAATQWFGEVGALRTLELLSPFEVTKAIKLRLL
HHHHHHHCCCCCEEEEEEHHHEEEECCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
KTGHYKTHVELKNQQGRVMPCELKVRVLKSETGRAEAFVVSFTDLTIDIELKRLNYQANH
CCCCEEEEEEEECCCCCEEEHHHEEEEECCCCCCCEEEEEEEEEEEEEEEEEEECCCCCC
DPLTGLANRSKAMRRLQEKHDLGTSQHILFVDLDGFKAVNDQYGHAIGDQLLKVVAQRLM
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHCHHHHHHHHHHHHHHHHHHHH
SCVARRDLVSRLAGDEFLIAVREATSCEPIAQRIIESLSKPFLFGDITCGISASIGVSYW
HHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEC
PRDENTSLEEKINEADMAMYFAKKEGKNQFRSGLETVY
CCCCCCCHHHHHCHHHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]