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The map label for this gene is cdr [H]

Identifier: 156976922

GI number: 156976922

Start: 910628

End: 912331

Strand: Reverse

Name: cdr [H]

Synonym: VIBHAR_05707

Alternate gene names: 156976922

Gene position: 912331-910628 (Counterclockwise)

Preceding gene: 156976926

Following gene: 156976919

Centisome position: 41.39

GC content: 47.36

Gene sequence:

>1704_bases
ATGAGCAAAATCGTGATTATTGGTGGTGTTGCTGGCGGTGCATCTGCAGCAGCTCGCGCTCGTCGTCTTAGTGAAGACGC
AGAAATCATCATGTTTGAACGCGGTCCATTTGTATCATTTGCAAACTGTGGCTTGCCGTACCACATTGGTGGTGATATCC
AAGAACGCAGCAAACTGCTTCTTCAAACACCTGAAAGCTTTTTAGCGCGTTTCAGTGTTGATGTCCGTGTGATGAACGAA
GTGGTTTCTATTAACCGCCAAGACAAAACGGTTACGGTTAAGAACCTACTTGATGGCTCTGAATACCAAGAGAGCTATGA
CTTTCTTCTACTTAGCCCTGGTGCTGGTCCAGTAGTGCCGCCTATTCCGGGTATTGATAACCCGTTAACGCATTCGCTGC
GCAATATTCCAGATATGGATCGCATCATTAAGACGATCGAAACCAACAAAGTTGAACACGCTACCGTCGTTGGCGGTGGT
TTTATCGGTTTGGAAATGATGGAAGCGTTCCACCAGCTTGGCGTAAAAACCACATTGGTTGAAATGGCGGATCAAGTGAT
GACGCCCGTTGACCGAGAAATGGCTGGTTTTGCTCATGCTGAAATCCGAGAGAAAGGTATCGACCTACGTTTAGGCGTTG
CTCTATCTTCTGTTGAATACGTTGCGAACCAATCTATCGCGAACATAGAAGCGGGTGAAGATGACACGCACCAGCACCTT
CAAGGAAAACTGACGCTGTCTCTAAACAATGGTGATCAGCTGGATACCGATATCCTGATCATGGCGATTGGTGTACGCCC
TGAGACAAAACTCGCGCAAGAAGCCGGACTTCAAATTGGCTCACTAGGCGGTATCTATACCAACGAGTACATGCAAACCA
GCGATCCTTCCATCTATGCCGTTGGTGATGCGGTTGAAGAGAAAGACTTTGTCACTGGCGAACAAACACTTGTTCCGTTG
GCAGGGCCGGCAAACCGTCAAGGTCGCATGGCAGCAGACAACATGCTTGGCCGCCAAGAAACTTACCAAGGTACACAAGG
CACAGCGATCTGTAAGATCTTCGATTTAGCCGTCGCTTCTACTGGTAAAAATGAGAAGCAGCTTAAACGTGACAACATCA
CTTATGAAAAAGTGTATGTCCACACAGCAAGCCACGCGAGTTACTACCCTGGCGCAGAAACTGTGTCGTTCAAAATGCTG
TTTGATCCAGCAACCGGCAAAGTTTTAGGTGCACAAGCCGTAGGTAAAGATGGCGTTGATAAACGTATCGACGTAATGGC
AGTTGCACAGCGTGCTGGTATGACGGTAGAACAACTGCAACACCTTGAACTCACTTACGCGCCGCCGTATGGTTCAGCGA
AAGATGTGATTAACCAAGCGGCTTTCGTTGCGAACAACATCATGAACGGTGACGCAACAGCGATTCATTTTGATGAAATC
GACAACCTGTCAGAAAATCAAGTGCTGCTTGATGTTCGTAATCCGGGAGAATTAGAATCCGTAGGTTTCATTGAAGGCGC
GATCAATATTCCTGTCGACCAGCTTCGCCAACGTATGAATGAACTGCCTAAAGACAAAGAGATCGTGATTTATTGTCAGG
TCGGCTTGCGCGGTAACGTCGCTTATCGTCAACTGGTCAATTCAGGATTTAAAGCACGTAACCTACTTGGCGGTTACCGT
ACCTATAAGTTCGCAAGAGCTTAA

Upstream 100 bases:

>100_bases
TATCATTAAGTCAATACTAATGTAGAATAAACAACATTAGACATAGCTAATTCAATTAAGTAAGGTGTAGGCGTTTTCGA
TCATTCAGTAGGAGACATCC

Downstream 100 bases:

>100_bases
TCTCTGATTATAAATATCTAAGTTTAGGGCTGAAAAAAGGGGCATATTATGTGCCCCTTTCTACATTTCGGATTCGACTA
AATGAATAATCTTGGTCGCT

Product: hypothetical protein

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MSKIVIIGGVAGGASAAARARRLSEDAEIIMFERGPFVSFANCGLPYHIGGDIQERSKLLLQTPESFLARFSVDVRVMNE
VVSINRQDKTVTVKNLLDGSEYQESYDFLLLSPGAGPVVPPIPGIDNPLTHSLRNIPDMDRIIKTIETNKVEHATVVGGG
FIGLEMMEAFHQLGVKTTLVEMADQVMTPVDREMAGFAHAEIREKGIDLRLGVALSSVEYVANQSIANIEAGEDDTHQHL
QGKLTLSLNNGDQLDTDILIMAIGVRPETKLAQEAGLQIGSLGGIYTNEYMQTSDPSIYAVGDAVEEKDFVTGEQTLVPL
AGPANRQGRMAADNMLGRQETYQGTQGTAICKIFDLAVASTGKNEKQLKRDNITYEKVYVHTASHASYYPGAETVSFKML
FDPATGKVLGAQAVGKDGVDKRIDVMAVAQRAGMTVEQLQHLELTYAPPYGSAKDVINQAAFVANNIMNGDATAIHFDEI
DNLSENQVLLDVRNPGELESVGFIEGAINIPVDQLRQRMNELPKDKEIVIYCQVGLRGNVAYRQLVNSGFKARNLLGGYR
TYKFARA

Sequences:

>Translated_567_residues
MSKIVIIGGVAGGASAAARARRLSEDAEIIMFERGPFVSFANCGLPYHIGGDIQERSKLLLQTPESFLARFSVDVRVMNE
VVSINRQDKTVTVKNLLDGSEYQESYDFLLLSPGAGPVVPPIPGIDNPLTHSLRNIPDMDRIIKTIETNKVEHATVVGGG
FIGLEMMEAFHQLGVKTTLVEMADQVMTPVDREMAGFAHAEIREKGIDLRLGVALSSVEYVANQSIANIEAGEDDTHQHL
QGKLTLSLNNGDQLDTDILIMAIGVRPETKLAQEAGLQIGSLGGIYTNEYMQTSDPSIYAVGDAVEEKDFVTGEQTLVPL
AGPANRQGRMAADNMLGRQETYQGTQGTAICKIFDLAVASTGKNEKQLKRDNITYEKVYVHTASHASYYPGAETVSFKML
FDPATGKVLGAQAVGKDGVDKRIDVMAVAQRAGMTVEQLQHLELTYAPPYGSAKDVINQAAFVANNIMNGDATAIHFDEI
DNLSENQVLLDVRNPGELESVGFIEGAINIPVDQLRQRMNELPKDKEIVIYCQVGLRGNVAYRQLVNSGFKARNLLGGYR
TYKFARA
>Mature_566_residues
SKIVIIGGVAGGASAAARARRLSEDAEIIMFERGPFVSFANCGLPYHIGGDIQERSKLLLQTPESFLARFSVDVRVMNEV
VSINRQDKTVTVKNLLDGSEYQESYDFLLLSPGAGPVVPPIPGIDNPLTHSLRNIPDMDRIIKTIETNKVEHATVVGGGF
IGLEMMEAFHQLGVKTTLVEMADQVMTPVDREMAGFAHAEIREKGIDLRLGVALSSVEYVANQSIANIEAGEDDTHQHLQ
GKLTLSLNNGDQLDTDILIMAIGVRPETKLAQEAGLQIGSLGGIYTNEYMQTSDPSIYAVGDAVEEKDFVTGEQTLVPLA
GPANRQGRMAADNMLGRQETYQGTQGTAICKIFDLAVASTGKNEKQLKRDNITYEKVYVHTASHASYYPGAETVSFKMLF
DPATGKVLGAQAVGKDGVDKRIDVMAVAQRAGMTVEQLQHLELTYAPPYGSAKDVINQAAFVANNIMNGDATAIHFDEID
NLSENQVLLDVRNPGELESVGFIEGAINIPVDQLRQRMNELPKDKEIVIYCQVGLRGNVAYRQLVNSGFKARNLLGGYRT
YKFARA

Specific function: Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=442, Percent_Identity=24.2081447963801, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI226437568, Length=425, Percent_Identity=24.9411764705882, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI65787454, Length=425, Percent_Identity=24.9411764705882, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI91199540, Length=385, Percent_Identity=25.4545454545455, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1789765, Length=337, Percent_Identity=26.7062314540059, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1789065, Length=331, Percent_Identity=26.8882175226586, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1786307, Length=323, Percent_Identity=25.6965944272446, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI87082354, Length=326, Percent_Identity=26.9938650306748, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788892, Length=207, Percent_Identity=27.536231884058, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=308, Percent_Identity=24.3506493506494, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321091, Length=345, Percent_Identity=25.7971014492754, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21358499, Length=375, Percent_Identity=24.2666666666667, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 61738; Mature: 61607

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIVIIGGVAGGASAAARARRLSEDAEIIMFERGPFVSFANCGLPYHIGGDIQERSKLL
CCEEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCEECCCCHHHHHHHH
LQTPESFLARFSVDVRVMNEVVSINRQDKTVTVKNLLDGSEYQESYDFLLLSPGAGPVVP
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCHHHHCCCCEEEECCCCCCCCC
PIPGIDNPLTHSLRNIPDMDRIIKTIETNKVEHATVVGGGFIGLEMMEAFHQLGVKTTLV
CCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHH
EMADQVMTPVDREMAGFAHAEIREKGIDLRLGVALSSVEYVANQSIANIEAGEDDTHQHL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHC
QGKLTLSLNNGDQLDTDILIMAIGVRPETKLAQEAGLQIGSLGGIYTNEYMQTSDPSIYA
CEEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHCCEEECCCCEEECCCEECCCCCEEE
VGDAVEEKDFVTGEQTLVPLAGPANRQGRMAADNMLGRQETYQGTQGTAICKIFDLAVAS
ECCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHCCCHHHCCCCCCCEEEEEEEHHHHC
TGKNEKQLKRDNITYEKVYVHTASHASYYPGAETVSFKMLFDPATGKVLGAQAVGKDGVD
CCCCHHHHHHCCCEEEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCEEECHHCCCCCCC
KRIDVMAVAQRAGMTVEQLQHLELTYAPPYGSAKDVINQAAFVANNIMNGDATAIHFDEI
HHHHHHHHHHHHCCCHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHC
DNLSENQVLLDVRNPGELESVGFIEGAINIPVDQLRQRMNELPKDKEIVIYCQVGLRGNV
CCCCCCEEEEEECCCCCCCCCEEEECEECCCHHHHHHHHHHCCCCCEEEEEEECCCCCCH
AYRQLVNSGFKARNLLGGYRTYKFARA
HHHHHHHCCCHHHHHHCCHHHEEEECC
>Mature Secondary Structure 
SKIVIIGGVAGGASAAARARRLSEDAEIIMFERGPFVSFANCGLPYHIGGDIQERSKLL
CEEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCCEECCCCHHHHHHHH
LQTPESFLARFSVDVRVMNEVVSINRQDKTVTVKNLLDGSEYQESYDFLLLSPGAGPVVP
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHCCHHHHCCCCEEEECCCCCCCCC
PIPGIDNPLTHSLRNIPDMDRIIKTIETNKVEHATVVGGGFIGLEMMEAFHQLGVKTTLV
CCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCHHHHH
EMADQVMTPVDREMAGFAHAEIREKGIDLRLGVALSSVEYVANQSIANIEAGEDDTHQHL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCHHHHHC
QGKLTLSLNNGDQLDTDILIMAIGVRPETKLAQEAGLQIGSLGGIYTNEYMQTSDPSIYA
CEEEEEEECCCCCCCCEEEEEEECCCCCHHHHHHHCCEEECCCCEEECCCEECCCCCEEE
VGDAVEEKDFVTGEQTLVPLAGPANRQGRMAADNMLGRQETYQGTQGTAICKIFDLAVAS
ECCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHHHCCCHHHCCCCCCCEEEEEEEHHHHC
TGKNEKQLKRDNITYEKVYVHTASHASYYPGAETVSFKMLFDPATGKVLGAQAVGKDGVD
CCCCHHHHHHCCCEEEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCEEECHHCCCCCCC
KRIDVMAVAQRAGMTVEQLQHLELTYAPPYGSAKDVINQAAFVANNIMNGDATAIHFDEI
HHHHHHHHHHHHCCCHHHHHCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEHHHC
DNLSENQVLLDVRNPGELESVGFIEGAINIPVDQLRQRMNELPKDKEIVIYCQVGLRGNV
CCCCCCEEEEEECCCCCCCCCEEEECEECCCHHHHHHHHHHCCCCCEEEEEEECCCCCCH
AYRQLVNSGFKARNLLGGYRTYKFARA
HHHHHHHCCCHHHHHHCCHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA