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The map label for this gene is cyaB [H]

Identifier: 156976823

GI number: 156976823

Start: 800262

End: 801944

Strand: Direct

Name: cyaB [H]

Synonym: VIBHAR_05599

Alternate gene names: 156976823

Gene position: 800262-801944 (Clockwise)

Preceding gene: 156976822

Following gene: 156976824

Centisome position: 36.31

GC content: 45.63

Gene sequence:

>1683_bases
ATGAAGTCCATATTGTTGGTTGACGACAGCAAAACGGTTCTGCTCTACATGACCAGTGCATTGCAAAAGCAAGGGTACGA
GGTCATTGCCGTTGAAGATGGTGAGTCTGCGTTAGAAGTACTGAATCACCGCACTGACATTCAGTTTGTCCTCAGTGATT
TGATGATGCCGGGCATTAGTGGCATTGAGCTTTGTCGTGAGCTTAAGTCGTCGGCGTTTTCTCGTTATATCTTCTTTGTT
CTCCTTTCTTCATATAACGATGAAGAATCCATCATCAAAGGCATGGATGCAGGTGCCGATGACTTTGTTGATAAGAAGAC
CTCTGTCGCTGAGCTGCAAGCGCGGATTCGAGCGGGTTTTCGTACTTTAGAGCTGCACTATACGCTCACGACAAAAAACC
AAGAGCTCGATTTAGCGTATCAAACCATTCAGCAGGATCTGGATTCTGCTGGAGAGTTAATGGGGCAACTGTTGCCCGTT
GAAGAACAGATTCACACGGCACAATTTAGATTCACTTATGTCCCTTGTACCAAGATCGGTGGGGATATGTTGGGTTATGT
CGAGCTTGATGAATCGCATGTTGCGTTTTATGTCTTCGATGTTTCCGGGCACGGTATTTCTTCGGCGTTAATGGCGTTCT
CGATTCAACAGGCTTTGTTACAACGTAACAAATTGGAGTCGATAACGTTAGATTGGAGTGACAACGAATACCGCATCAGT
AAGCCTGCGGCTGTGATTGAAAGGCTCAATCGACGCTACCAGCAAACGCAGAACGGCAAGCTCTATTTCACTATCGAATA
CGCCGTGTTGAACACCAAAACCGGTGAACTAAACTATTGCACAGCAGGGCATCCTAAATTTGTTTGGCAACAGACGAAAC
AAAACCGCTTGGAACTTGTTGGCGACAACAACTTCATTGTCGGGGCATTGGAGCCAATGATATACCAAGGTGGACGTATC
CAACTCAAGCCTGATGACGCGCTTTGGTTTTTCTCCGATGGCTTATTGGAAGCTAAGCAAGGCGAGGAGCTTTACGGCAT
TGACCGACTGTTAGTCAACATCGAAAGGAGTAAAGCGATGCCAGAAAAAGCACAAACTAATGCTGTTTTAAAGCAAGTGC
AAAACTGGCAAGGAAAACCAGAACTCGACGATGATGTGAGCTTGTTGAAAGTGCAATGGTTGGGCTGTGCACAATCGCGA
GCCGTTAATTCGCCGAGGGTGGTGTTCCAGAAATCCTATCAAGCATCTTTAGAAGTTTCGCGCCAAGCGAGTCTCGAATT
GGTTGAGTTCCTTCAACAACATTCGGTTTCTTCTCATGCCATGCAAGCGTTGGAGTTATGTGTGGTAGAACTCATGAACA
ATGCGTTTATTCATGCCTACCAAGAGCAAGCAGGGAAAACGGTTGAGTTAGAATGCGAAGTGCTTCGAGGTGAAAAAACA
AAAGTTGAGCTGCGCGTGGCTGATTACGGAAACGGTATTGATGACGACACGTTCAAAGGTCACATCTCTAAGCAAATTGA
AGCCCCTAACTTGCTCGATGAAGACAGTTGGTTGCCTTCTGGGCGAGGGCTAATATTGATCGCTCAAATGACAAACGGGT
TTTCTGTATCACATCAAGGGGAGCGTAATTGTTTTACGGTGGTGATATCTCTCGACGAAAAGGCAAAGTCTATAATTCTT
TAA

Upstream 100 bases:

>100_bases
CCGTTATCAACACCAACTTTTAGCGGAAGATTACAGCCGTTTCAGAGATGCCCAATCCATGAATAGCGTGCTGCAATAGA
ACAAACGGGCAAGGAGACGC

Downstream 100 bases:

>100_bases
AGGCTTTACTCGTGGAAGTCAAACATGTCGCAAATAGAAATCAAACGGGACCGGCCACGTGTCGGAAAGCAGACTGGATT
GATGCGACAAAAAGCTGTAT

Product: response regulator receiver

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2; AC2 [H]

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MKSILLVDDSKTVLLYMTSALQKQGYEVIAVEDGESALEVLNHRTDIQFVLSDLMMPGISGIELCRELKSSAFSRYIFFV
LLSSYNDEESIIKGMDAGADDFVDKKTSVAELQARIRAGFRTLELHYTLTTKNQELDLAYQTIQQDLDSAGELMGQLLPV
EEQIHTAQFRFTYVPCTKIGGDMLGYVELDESHVAFYVFDVSGHGISSALMAFSIQQALLQRNKLESITLDWSDNEYRIS
KPAAVIERLNRRYQQTQNGKLYFTIEYAVLNTKTGELNYCTAGHPKFVWQQTKQNRLELVGDNNFIVGALEPMIYQGGRI
QLKPDDALWFFSDGLLEAKQGEELYGIDRLLVNIERSKAMPEKAQTNAVLKQVQNWQGKPELDDDVSLLKVQWLGCAQSR
AVNSPRVVFQKSYQASLEVSRQASLELVEFLQQHSVSSHAMQALELCVVELMNNAFIHAYQEQAGKTVELECEVLRGEKT
KVELRVADYGNGIDDDTFKGHISKQIEAPNLLDEDSWLPSGRGLILIAQMTNGFSVSHQGERNCFTVVISLDEKAKSIIL

Sequences:

>Translated_560_residues
MKSILLVDDSKTVLLYMTSALQKQGYEVIAVEDGESALEVLNHRTDIQFVLSDLMMPGISGIELCRELKSSAFSRYIFFV
LLSSYNDEESIIKGMDAGADDFVDKKTSVAELQARIRAGFRTLELHYTLTTKNQELDLAYQTIQQDLDSAGELMGQLLPV
EEQIHTAQFRFTYVPCTKIGGDMLGYVELDESHVAFYVFDVSGHGISSALMAFSIQQALLQRNKLESITLDWSDNEYRIS
KPAAVIERLNRRYQQTQNGKLYFTIEYAVLNTKTGELNYCTAGHPKFVWQQTKQNRLELVGDNNFIVGALEPMIYQGGRI
QLKPDDALWFFSDGLLEAKQGEELYGIDRLLVNIERSKAMPEKAQTNAVLKQVQNWQGKPELDDDVSLLKVQWLGCAQSR
AVNSPRVVFQKSYQASLEVSRQASLELVEFLQQHSVSSHAMQALELCVVELMNNAFIHAYQEQAGKTVELECEVLRGEKT
KVELRVADYGNGIDDDTFKGHISKQIEAPNLLDEDSWLPSGRGLILIAQMTNGFSVSHQGERNCFTVVISLDEKAKSIIL
>Mature_560_residues
MKSILLVDDSKTVLLYMTSALQKQGYEVIAVEDGESALEVLNHRTDIQFVLSDLMMPGISGIELCRELKSSAFSRYIFFV
LLSSYNDEESIIKGMDAGADDFVDKKTSVAELQARIRAGFRTLELHYTLTTKNQELDLAYQTIQQDLDSAGELMGQLLPV
EEQIHTAQFRFTYVPCTKIGGDMLGYVELDESHVAFYVFDVSGHGISSALMAFSIQQALLQRNKLESITLDWSDNEYRIS
KPAAVIERLNRRYQQTQNGKLYFTIEYAVLNTKTGELNYCTAGHPKFVWQQTKQNRLELVGDNNFIVGALEPMIYQGGRI
QLKPDDALWFFSDGLLEAKQGEELYGIDRLLVNIERSKAMPEKAQTNAVLKQVQNWQGKPELDDDVSLLKVQWLGCAQSR
AVNSPRVVFQKSYQASLEVSRQASLELVEFLQQHSVSSHAMQALELCVVELMNNAFIHAYQEQAGKTVELECEVLRGEKT
KVELRVADYGNGIDDDTFKGHISKQIEAPNLLDEDSWLPSGRGLILIAQMTNGFSVSHQGERNCFTVVISLDEKAKSIIL

Specific function: This Protein Is A Positive Regulator For The Phosphate Regulon. Transcription Of This Operon Is Positively Regulated By Phob And Phor When Phosphate Is Limited. [C]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=122, Percent_Identity=34.4262295081967, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082012, Length=144, Percent_Identity=29.8611111111111, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=33.8983050847458, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786911, Length=170, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00072 Response_reg [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 63049; Mature: 63049

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSILLVDDSKTVLLYMTSALQKQGYEVIAVEDGESALEVLNHRTDIQFVLSDLMMPGIS
CCEEEEECCCCEEEEEEEHHHHHCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHCCCCC
GIELCRELKSSAFSRYIFFVLLSSYNDEESIIKGMDAGADDFVDKKTSVAELQARIRAGF
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHCCC
RTLELHYTLTTKNQELDLAYQTIQQDLDSAGELMGQLLPVEEQIHTAQFRFTYVPCTKIG
EEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCEEEEEEEEEEHHHCC
GDMLGYVELDESHVAFYVFDVSGHGISSALMAFSIQQALLQRNKLESITLDWSDNEYRIS
CCEEEEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEC
KPAAVIERLNRRYQQTQNGKLYFTIEYAVLNTKTGELNYCTAGHPKFVWQQTKQNRLELV
CHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEECCCCHHHHHHCCCCCEEEE
GDNNFIVGALEPMIYQGGRIQLKPDDALWFFSDGLLEAKQGEELYGIDRLLVNIERSKAM
CCCCEEEEECCHHHCCCCEEEECCCCEEEEEECCCEECCCCCCHHCHHHHEEEEHHHHCC
PEKAQTNAVLKQVQNWQGKPELDDDVSLLKVQWLGCAQSRAVNSPRVVFQKSYQASLEVS
CHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCEEEECCHHHHHHHH
RQASLELVEFLQQHSVSSHAMQALELCVVELMNNAFIHAYQEQAGKTVELECEVLRGEKT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHEEEEHHHCCCEEEEEEEEECCCCE
KVELRVADYGNGIDDDTFKGHISKQIEAPNLLDEDSWLPSGRGLILIAQMTNGFSVSHQG
EEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEECCCC
ERNCFTVVISLDEKAKSIIL
CCCEEEEEEEECCCHHHCCC
>Mature Secondary Structure
MKSILLVDDSKTVLLYMTSALQKQGYEVIAVEDGESALEVLNHRTDIQFVLSDLMMPGIS
CCEEEEECCCCEEEEEEEHHHHHCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHCCCCC
GIELCRELKSSAFSRYIFFVLLSSYNDEESIIKGMDAGADDFVDKKTSVAELQARIRAGF
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHCCC
RTLELHYTLTTKNQELDLAYQTIQQDLDSAGELMGQLLPVEEQIHTAQFRFTYVPCTKIG
EEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCEEEEEEEEEEHHHCC
GDMLGYVELDESHVAFYVFDVSGHGISSALMAFSIQQALLQRNKLESITLDWSDNEYRIS
CCEEEEEEECCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEC
KPAAVIERLNRRYQQTQNGKLYFTIEYAVLNTKTGELNYCTAGHPKFVWQQTKQNRLELV
CHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEECCCCHHHHHHCCCCCEEEE
GDNNFIVGALEPMIYQGGRIQLKPDDALWFFSDGLLEAKQGEELYGIDRLLVNIERSKAM
CCCCEEEEECCHHHCCCCEEEECCCCEEEEEECCCEECCCCCCHHCHHHHEEEEHHHHCC
PEKAQTNAVLKQVQNWQGKPELDDDVSLLKVQWLGCAQSRAVNSPRVVFQKSYQASLEVS
CHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCHHHHCCCCCCEEEECCHHHHHHHH
RQASLELVEFLQQHSVSSHAMQALELCVVELMNNAFIHAYQEQAGKTVELECEVLRGEKT
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHEEEEHHHCCCEEEEEEEEECCCCE
KVELRVADYGNGIDDDTFKGHISKQIEAPNLLDEDSWLPSGRGLILIAQMTNGFSVSHQG
EEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCEEECCCC
ERNCFTVVISLDEKAKSIIL
CCCEEEEEEEECCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]