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The map label for this gene is bcd [H]

Identifier: 156976705

GI number: 156976705

Start: 692217

End: 693386

Strand: Reverse

Name: bcd [H]

Synonym: VIBHAR_05480

Alternate gene names: 156976705

Gene position: 693386-692217 (Counterclockwise)

Preceding gene: 156976706

Following gene: 156976704

Centisome position: 31.46

GC content: 51.71

Gene sequence:

>1170_bases
ATGAAAAGCAGCTACACCCAACTCAACTTTGGCCTTGGTGAAACCATCGATATGCTCCGAGACCACGTCAACGCGTTTGC
CACCGAGCATATCGCCCCTATCGCCTCAGATATCGACCGCGACAACCAATTCCCCAATCATTTGTGGTCCAAGTTTGGTG
AAATGGGTTTGCTCGGCGTGACCGTCGACGAAGAGTTCGGTGGTGCAGGCATGGGCTACCTTGCTCATGTTGTTGCAATG
GAAGAGATCAGCCGAGCTTCGGCGCCTGTCGCGCTCAGTTACGGCGCACATTCCAACCTTTGTGTTAACCAAATCTTTCG
CAATGGATCCCCTGCTCAACGAGAAAAGTACCTACCTAAACTCATCGATGGTTCTCACGTTGGCGCACTAGCCATGAGTG
AGCCGAACTCAGGTTCTGACGTGGTTAGCATGCAGCTTCGTGCTGAAGACAAAGGCGATCACTATCTGATGAATGGTAAT
AAAATGTGGATCACCAACGGGCCTGATGCCGACACCTTAGTGGTCTACGCGAAAACCGATCCCAATGGCGGCTCTCGTGG
TATCACCGCTTTCATTATTGAGCGAGAGTTTGAAGGCTTTAGCCATGCACAGAAGCTCGACAAACTTGGTATGCGCGGCT
CCAACACCTGTGAATTAGTGTTCCAAGATTGTGTCGTGCCTAAAGAAAATGTGTTGGGTGAATTAAACCGTGGTGTTGAA
GTGTTAATGAGTGGCTTAGATTACGAACGCGTGGTACTAGCCGCCGGCCCGCTTGGCATCATGCAAGCCTGCATGGACGA
AGTGGTTCCGTATGTGCATGACCGCAAACAGTTCGGCAAATCCATTGGTGAGTTCCAACTGGTACAAGGAAAGCTTGCTG
ACATGTATTCACGCATGAACGCCGCCAAAGCTTACGTTTATACCGTCGCTGCCGCGTGCGACCGAGGTGAATGCACACGT
AAAGACGCCGCTGGCGTGATCCTTTACAGCGCCGAACTCGCCACGCAAATGTCCCTCGATGCTATTCAGCTGTTGGGCGG
TAATGGCTACATCAACGAATACGCGACCGGGCGCTTGCTACGCGACGCCAAACTGTATGAGATTGGCGCTGGCACCTCTG
AAATTCGCCGTATGTTAATTGGACGAGAGCTGTTCGAAGAGTCTCGCTAA

Upstream 100 bases:

>100_bases
GAGCAATAAAAACAAGAACAACCATAATTTCCAATCCCAAGCAGTGTAACTCGAACCTTATCCGTACTAACAACCGCAGT
ACTCGCAACAGGGAAATGTT

Downstream 100 bases:

>100_bases
ACCACCGACAAGGAAGTCACAATGGCAATCATTAAAAGTAAAACCAAGCCAACCGACGAGCTGTTCTTGTCGAACAAAGC
GGTCATGACCGAGTTGGTGA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MKSSYTQLNFGLGETIDMLRDHVNAFATEHIAPIASDIDRDNQFPNHLWSKFGEMGLLGVTVDEEFGGAGMGYLAHVVAM
EEISRASAPVALSYGAHSNLCVNQIFRNGSPAQREKYLPKLIDGSHVGALAMSEPNSGSDVVSMQLRAEDKGDHYLMNGN
KMWITNGPDADTLVVYAKTDPNGGSRGITAFIIEREFEGFSHAQKLDKLGMRGSNTCELVFQDCVVPKENVLGELNRGVE
VLMSGLDYERVVLAAGPLGIMQACMDEVVPYVHDRKQFGKSIGEFQLVQGKLADMYSRMNAAKAYVYTVAAACDRGECTR
KDAAGVILYSAELATQMSLDAIQLLGGNGYINEYATGRLLRDAKLYEIGAGTSEIRRMLIGRELFEESR

Sequences:

>Translated_389_residues
MKSSYTQLNFGLGETIDMLRDHVNAFATEHIAPIASDIDRDNQFPNHLWSKFGEMGLLGVTVDEEFGGAGMGYLAHVVAM
EEISRASAPVALSYGAHSNLCVNQIFRNGSPAQREKYLPKLIDGSHVGALAMSEPNSGSDVVSMQLRAEDKGDHYLMNGN
KMWITNGPDADTLVVYAKTDPNGGSRGITAFIIEREFEGFSHAQKLDKLGMRGSNTCELVFQDCVVPKENVLGELNRGVE
VLMSGLDYERVVLAAGPLGIMQACMDEVVPYVHDRKQFGKSIGEFQLVQGKLADMYSRMNAAKAYVYTVAAACDRGECTR
KDAAGVILYSAELATQMSLDAIQLLGGNGYINEYATGRLLRDAKLYEIGAGTSEIRRMLIGRELFEESR
>Mature_389_residues
MKSSYTQLNFGLGETIDMLRDHVNAFATEHIAPIASDIDRDNQFPNHLWSKFGEMGLLGVTVDEEFGGAGMGYLAHVVAM
EEISRASAPVALSYGAHSNLCVNQIFRNGSPAQREKYLPKLIDGSHVGALAMSEPNSGSDVVSMQLRAEDKGDHYLMNGN
KMWITNGPDADTLVVYAKTDPNGGSRGITAFIIEREFEGFSHAQKLDKLGMRGSNTCELVFQDCVVPKENVLGELNRGVE
VLMSGLDYERVVLAAGPLGIMQACMDEVVPYVHDRKQFGKSIGEFQLVQGKLADMYSRMNAAKAYVYTVAAACDRGECTR
KDAAGVILYSAELATQMSLDAIQLLGGNGYINEYATGRLLRDAKLYEIGAGTSEIRRMLIGRELFEESR

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=64.8936170212766, Blast_Score=523, Evalue=1e-148,
Organism=Homo sapiens, GI226958414, Length=337, Percent_Identity=67.3590504451039, Blast_Score=494, Evalue=1e-140,
Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=38.8888888888889, Blast_Score=278, Evalue=6e-75,
Organism=Homo sapiens, GI4501859, Length=367, Percent_Identity=34.0599455040872, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI21361497, Length=376, Percent_Identity=37.2340425531915, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI4557231, Length=379, Percent_Identity=34.5646437994723, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI187960098, Length=379, Percent_Identity=34.5646437994723, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI76496475, Length=381, Percent_Identity=33.8582677165354, Blast_Score=218, Evalue=5e-57,
Organism=Homo sapiens, GI4557235, Length=340, Percent_Identity=36.4705882352941, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI4501857, Length=375, Percent_Identity=32.5333333333333, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI7656849, Length=389, Percent_Identity=30.0771208226221, Blast_Score=195, Evalue=8e-50,
Organism=Homo sapiens, GI4503943, Length=372, Percent_Identity=30.6451612903226, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI7669494, Length=368, Percent_Identity=31.25, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI211971008, Length=375, Percent_Identity=23.4666666666667, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI48976061, Length=375, Percent_Identity=23.4666666666667, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1786223, Length=363, Percent_Identity=27.2727272727273, Blast_Score=162, Evalue=5e-41,
Organism=Escherichia coli, GI87081958, Length=383, Percent_Identity=28.1984334203655, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI87082384, Length=283, Percent_Identity=26.8551236749117, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081702, Length=335, Percent_Identity=25.0746268656716, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17538396, Length=380, Percent_Identity=61.8421052631579, Blast_Score=496, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17506239, Length=371, Percent_Identity=33.4231805929919, Blast_Score=241, Evalue=7e-64,
Organism=Caenorhabditis elegans, GI17569725, Length=382, Percent_Identity=34.2931937172775, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI17508101, Length=360, Percent_Identity=32.5, Blast_Score=228, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI17534899, Length=383, Percent_Identity=32.3759791122715, Blast_Score=228, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17570075, Length=387, Percent_Identity=31.266149870801, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI71985184, Length=350, Percent_Identity=35.1428571428571, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI71990804, Length=294, Percent_Identity=36.3945578231293, Blast_Score=207, Evalue=6e-54,
Organism=Caenorhabditis elegans, GI17533517, Length=379, Percent_Identity=30.6068601583113, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71982178, Length=274, Percent_Identity=36.1313868613139, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17505929, Length=372, Percent_Identity=32.5268817204301, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=36.7965367965368, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71985192, Length=310, Percent_Identity=34.1935483870968, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17551932, Length=368, Percent_Identity=30.4347826086957, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17534353, Length=380, Percent_Identity=28.1578947368421, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI17531909, Length=246, Percent_Identity=29.6747967479675, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI86563383, Length=283, Percent_Identity=25.7950530035336, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI86563381, Length=283, Percent_Identity=25.7950530035336, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355753, Length=384, Percent_Identity=63.28125, Blast_Score=498, Evalue=1e-141,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=40.1595744680851, Blast_Score=295, Evalue=3e-80,
Organism=Drosophila melanogaster, GI24646207, Length=376, Percent_Identity=36.968085106383, Blast_Score=259, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24666513, Length=365, Percent_Identity=33.4246575342466, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24660351, Length=384, Percent_Identity=34.375, Blast_Score=239, Evalue=2e-63,
Organism=Drosophila melanogaster, GI281363737, Length=353, Percent_Identity=34.8441926345609, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI19920834, Length=377, Percent_Identity=28.9124668435013, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 42534; Mature: 42534

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSYTQLNFGLGETIDMLRDHVNAFATEHIAPIASDIDRDNQFPNHLWSKFGEMGLLGV
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEE
TVDEEFGGAGMGYLAHVVAMEEISRASAPVALSYGAHSNLCVNQIFRNGSPAQREKYLPK
EECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCHHHHHHCHH
LIDGSHVGALAMSEPNSGSDVVSMQLRAEDKGDHYLMNGNKMWITNGPDADTLVVYAKTD
HCCCCCCCEEEECCCCCCCCEEEEEEEECCCCCEEEECCCEEEEECCCCCCEEEEEEEEC
PNGGSRGITAFIIEREFEGFSHAQKLDKLGMRGSNTCELVFQDCVVPKENVLGELNRGVE
CCCCCCCEEEEEEEEHHCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
VLMSGLDYERVVLAAGPLGIMQACMDEVVPYVHDRKQFGKSIGEFQLVQGKLADMYSRMN
HHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
AAKAYVYTVAAACDRGECTRKDAAGVILYSAELATQMSLDAIQLLGGNGYINEYATGRLL
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHEECCCCCCCHHHHCHHH
RDAKLYEIGAGTSEIRRMLIGRELFEESR
HCCEEEEECCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSSYTQLNFGLGETIDMLRDHVNAFATEHIAPIASDIDRDNQFPNHLWSKFGEMGLLGV
CCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEE
TVDEEFGGAGMGYLAHVVAMEEISRASAPVALSYGAHSNLCVNQIFRNGSPAQREKYLPK
EECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHCCCCHHHHHHCHH
LIDGSHVGALAMSEPNSGSDVVSMQLRAEDKGDHYLMNGNKMWITNGPDADTLVVYAKTD
HCCCCCCCEEEECCCCCCCCEEEEEEEECCCCCEEEECCCEEEEECCCCCCEEEEEEEEC
PNGGSRGITAFIIEREFEGFSHAQKLDKLGMRGSNTCELVFQDCVVPKENVLGELNRGVE
CCCCCCCEEEEEEEEHHCCHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
VLMSGLDYERVVLAAGPLGIMQACMDEVVPYVHDRKQFGKSIGEFQLVQGKLADMYSRMN
HHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
AAKAYVYTVAAACDRGECTRKDAAGVILYSAELATQMSLDAIQLLGGNGYINEYATGRLL
HHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHEECCCCCCCHHHHCHHH
RDAKLYEIGAGTSEIRRMLIGRELFEESR
HCCEEEEECCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]