Click here to switch to the map view.

The map label for this gene is yngE [H]

Identifier: 156976704

GI number: 156976704

Start: 690591

End: 692195

Strand: Reverse

Name: yngE [H]

Synonym: VIBHAR_05479

Alternate gene names: 156976704

Gene position: 692195-690591 (Counterclockwise)

Preceding gene: 156976705

Following gene: 156976703

Centisome position: 31.41

GC content: 51.96

Gene sequence:

>1605_bases
ATGGCAATCATTAAAAGTAAAACCAAGCCAACCGACGAGCTGTTCTTGTCGAACAAAGCGGTCATGACCGAGTTGGTGAA
CAACCTCAATGCCAATATCAAAGCTATCAAACAGGGTGGCGGACAGAAAGCTATCGACCGCCAACGCCTGAAAGGAAAGC
TGCCCGTCCGTGAGCGCGTCACGCTCCTTTTGGATGAAGGCAGCGAGTTTCTTGAAGTCGGACAATTCGCAGCGTGGAAT
GTCTATGAAGAGTCGATACCTTGCGCAGGTGTCGTTGCGGGTATTGGCACCATTGAAGGCATTCAATGCATGGTGATCGC
CAACGACCCTTCAGTGAAAGGCGGCACCTATTACCCACTCACCGTGAAAAAGCATCTACGCGCGCAAGAGATCGCCCAAC
GTTGCCAACTGCCTTGCGTCTATCTGGTGGATTCTGGGGGAGCGAACCTCCCTCACCAAGCAGAAGTGTTTGCTGACAAA
GAGCACTTCGGACGCATCTTCTTCAATCAAGCCAGAATGTCGGCACAGGGCATTCCTCAAGTTGCAGTGGTGATGGGGCT
TTGTACCGCTGGTGGCGCTTATGTACCAGCGATGTCGGACGTTTCCATTATGGTCAAAGAGCAAGGCACCATCTTCTTGG
CAGGTCCACCGCTAGTAAAAGCCGCAACGGGAGAAATCGTCACCGATGAAGAATTGGGCGGTGCCGATGTGCACTGTCGC
AAGTCTGGCGTTGCCGATTACTATGCAGAAAATGACCAGCACGCATTACAGCTTGCGCGCGAAGCCATCTCAAATACTAA
TCAATCACTCCCCGTTCAAAGCGACAAAACCGTCTTGCCACCGCGTTACGACGCAGAAGAGATGTACGGCATCGTCAATG
CGAACCTTCGCTTGTCTTTTGATGTTCGAGAGATCATCGCTCGCGTGGTCGACGACTCAGACTTTGACGAGTTCAAGGCG
CTTTATGGCAAGACTTTAGTGTGTGGTTTCGCTCGAATCCACGGCAATTTGATTGGCATTGTGGCAAACAACGGCATCTT
GTTTTCAGAGTCCTCCCAGAAAGGCGCACACTTTATTGAGCTGTGTGCCAAACGCAAAATTCCCCTACTCTTTTTGCAAA
ACATCACTGGTTTTATGGTCGGCAAAAAGCTTGAAGCGGAAGGCATTGCCAAACACGGCGCGAAACTGGTGATGGCAGTC
GCCTGTGCGGACGTACCCAAGTTCACCGTGATTATTGGCGGCTCTTACGGCGCAGGCAACTACGGCATGTGCGGTCGCGC
TTATGACCCAACCATGATGTGGATGTGGCCGAACGCACGAATCTCAGTAATGGGCGGAGAACAAGCCGCGGGCGTGCTCA
CTCAAGTACGGCGAGAAGTGAAAAAGCGCCAAGGTGAAGACTGGCCAGAACCAGAAGAAAGTGCATTCCGAGATTCTATC
GTAGACTTGTATGAGTCTCAGGGGCATCCCTACTACGCCAGCGCACGCTTGTGGGATGACGGCATCATCGACCCGAAAGA
AACGCGTCAGGTGTTAGCTCAAGCGTTAAGAGCATCGCTCCATGCGCCAATTCCTGACAGCAACTTTGGCATATTCAGAA
TGTAG

Upstream 100 bases:

>100_bases
ACTGTATGAGATTGGCGCTGGCACCTCTGAAATTCGCCGTATGTTAATTGGACGAGAGCTGTTCGAAGAGTCTCGCTAAA
CCACCGACAAGGAAGTCACA

Downstream 100 bases:

>100_bases
CAATGTAGAAATCTAGAGAAGAAAGGACGTCACATGCAGGATCATCAACCGAGTATCATCCCCAATACAAAGCGACAAGA
TGAAGTACTTTGGAACGTCG

Product: propionyl-CoA carboxylase subunit beta

Products: ADP; phosphate; 3-methylglutaconyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MAIIKSKTKPTDELFLSNKAVMTELVNNLNANIKAIKQGGGQKAIDRQRLKGKLPVRERVTLLLDEGSEFLEVGQFAAWN
VYEESIPCAGVVAGIGTIEGIQCMVIANDPSVKGGTYYPLTVKKHLRAQEIAQRCQLPCVYLVDSGGANLPHQAEVFADK
EHFGRIFFNQARMSAQGIPQVAVVMGLCTAGGAYVPAMSDVSIMVKEQGTIFLAGPPLVKAATGEIVTDEELGGADVHCR
KSGVADYYAENDQHALQLAREAISNTNQSLPVQSDKTVLPPRYDAEEMYGIVNANLRLSFDVREIIARVVDDSDFDEFKA
LYGKTLVCGFARIHGNLIGIVANNGILFSESSQKGAHFIELCAKRKIPLLFLQNITGFMVGKKLEAEGIAKHGAKLVMAV
ACADVPKFTVIIGGSYGAGNYGMCGRAYDPTMMWMWPNARISVMGGEQAAGVLTQVRREVKKRQGEDWPEPEESAFRDSI
VDLYESQGHPYYASARLWDDGIIDPKETRQVLAQALRASLHAPIPDSNFGIFRM

Sequences:

>Translated_534_residues
MAIIKSKTKPTDELFLSNKAVMTELVNNLNANIKAIKQGGGQKAIDRQRLKGKLPVRERVTLLLDEGSEFLEVGQFAAWN
VYEESIPCAGVVAGIGTIEGIQCMVIANDPSVKGGTYYPLTVKKHLRAQEIAQRCQLPCVYLVDSGGANLPHQAEVFADK
EHFGRIFFNQARMSAQGIPQVAVVMGLCTAGGAYVPAMSDVSIMVKEQGTIFLAGPPLVKAATGEIVTDEELGGADVHCR
KSGVADYYAENDQHALQLAREAISNTNQSLPVQSDKTVLPPRYDAEEMYGIVNANLRLSFDVREIIARVVDDSDFDEFKA
LYGKTLVCGFARIHGNLIGIVANNGILFSESSQKGAHFIELCAKRKIPLLFLQNITGFMVGKKLEAEGIAKHGAKLVMAV
ACADVPKFTVIIGGSYGAGNYGMCGRAYDPTMMWMWPNARISVMGGEQAAGVLTQVRREVKKRQGEDWPEPEESAFRDSI
VDLYESQGHPYYASARLWDDGIIDPKETRQVLAQALRASLHAPIPDSNFGIFRM
>Mature_533_residues
AIIKSKTKPTDELFLSNKAVMTELVNNLNANIKAIKQGGGQKAIDRQRLKGKLPVRERVTLLLDEGSEFLEVGQFAAWNV
YEESIPCAGVVAGIGTIEGIQCMVIANDPSVKGGTYYPLTVKKHLRAQEIAQRCQLPCVYLVDSGGANLPHQAEVFADKE
HFGRIFFNQARMSAQGIPQVAVVMGLCTAGGAYVPAMSDVSIMVKEQGTIFLAGPPLVKAATGEIVTDEELGGADVHCRK
SGVADYYAENDQHALQLAREAISNTNQSLPVQSDKTVLPPRYDAEEMYGIVNANLRLSFDVREIIARVVDDSDFDEFKAL
YGKTLVCGFARIHGNLIGIVANNGILFSESSQKGAHFIELCAKRKIPLLFLQNITGFMVGKKLEAEGIAKHGAKLVMAVA
CADVPKFTVIIGGSYGAGNYGMCGRAYDPTMMWMWPNARISVMGGEQAAGVLTQVRREVKKRQGEDWPEPEESAFRDSIV
DLYESQGHPYYASARLWDDGIIDPKETRQVLAQALRASLHAPIPDSNFGIFRM

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=525, Percent_Identity=60.7619047619048, Blast_Score=656, Evalue=0.0,
Organism=Homo sapiens, GI119943100, Length=492, Percent_Identity=34.5528455284553, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI295821216, Length=512, Percent_Identity=33.3984375, Blast_Score=230, Evalue=3e-60,
Organism=Homo sapiens, GI310133460, Length=133, Percent_Identity=51.1278195488722, Blast_Score=126, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17552936, Length=538, Percent_Identity=60.7806691449814, Blast_Score=696, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147362, Length=498, Percent_Identity=34.136546184739, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI25147359, Length=498, Percent_Identity=34.136546184739, Blast_Score=255, Evalue=4e-68,
Organism=Drosophila melanogaster, GI24586065, Length=550, Percent_Identity=60.7272727272727, Blast_Score=700, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: 6.4.1.4

Molecular weight: Translated: 58277; Mature: 58145

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIIKSKTKPTDELFLSNKAVMTELVNNLNANIKAIKQGGGQKAIDRQRLKGKLPVRERV
CCEECCCCCCCHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCCHHHCE
TLLLDEGSEFLEVGQFAAWNVYEESIPCAGVVAGIGTIEGIQCMVIANDPSVKGGTYYPL
EEEECCCHHHHHHCCCCEEEEHHHCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEE
TVKKHLRAQEIAQRCQLPCVYLVDSGGANLPHQAEVFADKEHFGRIFFNQARMSAQGIPQ
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHEECHHHHHHHHHHHHHHCCCCCCH
VAVVMGLCTAGGAYVPAMSDVSIMVKEQGTIFLAGPPLVKAATGEIVTDEELGGADVHCR
HHHHHHHHHCCCEECCCCCCCEEEEECCCEEEEECCCEEEECCCCEEECCCCCCCCEEEC
KSGVADYYAENDQHALQLAREAISNTNQSLPVQSDKTVLPPRYDAEEMYGIVNANLRLSF
CCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHEEEECCEEEEE
DVREIIARVVDDSDFDEFKALYGKTLVCGFARIHGNLIGIVANNGILFSESSQKGAHFIE
CHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCEEEECCCCCCHHHHH
LCAKRKIPLLFLQNITGFMVGKKLEAEGIAKHGAKLVMAVACADVPKFTVIIGGSYGAGN
HHHHCCCCEEEECCCHHHHHCCCCCHHHHHHCCHHEEEEEHHCCCCEEEEEEECCCCCCC
YGMCGRAYDPTMMWMWPNARISVMGGEQAAGVLTQVRREVKKRQGEDWPEPEESAFRDSI
CCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
VDLYESQGHPYYASARLWDDGIIDPKETRQVLAQALRASLHAPIPDSNFGIFRM
HHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEC
>Mature Secondary Structure 
AIIKSKTKPTDELFLSNKAVMTELVNNLNANIKAIKQGGGQKAIDRQRLKGKLPVRERV
CEECCCCCCCHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHCCCCCHHHCE
TLLLDEGSEFLEVGQFAAWNVYEESIPCAGVVAGIGTIEGIQCMVIANDPSVKGGTYYPL
EEEECCCHHHHHHCCCCEEEEHHHCCCHHHHHHCCCCCCCEEEEEEECCCCCCCCEEEEE
TVKKHLRAQEIAQRCQLPCVYLVDSGGANLPHQAEVFADKEHFGRIFFNQARMSAQGIPQ
HHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHEECHHHHHHHHHHHHHHCCCCCCH
VAVVMGLCTAGGAYVPAMSDVSIMVKEQGTIFLAGPPLVKAATGEIVTDEELGGADVHCR
HHHHHHHHHCCCEECCCCCCCEEEEECCCEEEEECCCEEEECCCCEEECCCCCCCCEEEC
KSGVADYYAENDQHALQLAREAISNTNQSLPVQSDKTVLPPRYDAEEMYGIVNANLRLSF
CCCCCHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHEEEECCEEEEE
DVREIIARVVDDSDFDEFKALYGKTLVCGFARIHGNLIGIVANNGILFSESSQKGAHFIE
CHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCEEEEEECCCEEEECCCCCCHHHHH
LCAKRKIPLLFLQNITGFMVGKKLEAEGIAKHGAKLVMAVACADVPKFTVIIGGSYGAGN
HHHHCCCCEEEECCCHHHHHCCCCCHHHHHHCCHHEEEEEHHCCCCEEEEEEECCCCCCC
YGMCGRAYDPTMMWMWPNARISVMGGEQAAGVLTQVRREVKKRQGEDWPEPEESAFRDSI
CCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
VDLYESQGHPYYASARLWDDGIIDPKETRQVLAQALRASLHAPIPDSNFGIFRM
HHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 3-methylcrotonoyl-CoA; HCO3-

Specific reaction: ATP + 3-methylcrotonoyl-CoA + HCO3- = ADP + phosphate + 3-methylglutaconyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]