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The map label for this gene is torA [H]

Identifier: 156976678

GI number: 156976678

Start: 668670

End: 671096

Strand: Direct

Name: torA [H]

Synonym: VIBHAR_05452

Alternate gene names: 156976678

Gene position: 668670-671096 (Clockwise)

Preceding gene: 156976677

Following gene: 156976679

Centisome position: 30.34

GC content: 42.93

Gene sequence:

>2427_bases
ATGGAACTTTCTCGTAGAAGCTTTTTGAAATCAGCAGGGGTTGCCAGTACGGCAGCCCTCTCAGCACAGTTAACTCCTTT
AGCATTTGCCGCAAGCACAGATGTTGCCATTAAGAAGGCATTAACGGCTTCAAAATTCGGTACTTTTGAAGCAACGATCG
ATAATGGTGTCATTACTGGTGTGTCGCCGATTGATAAGTTAGGTATGACGATTGATTTAGCTGAATACGCTTATAAGACC
ATAAACAATCCTTCCCGAATTCAAACTCCTATGGTCAGAAAAGGTTACTTAGAGGGTAAAGGTGGTAATCGAGGTGACAA
CGAGTTTGTCCCTATTAGTTGGGAGCAAGCGATTGATTTGCTCTACAACAAGTTGGAGGAGGCACAGGTGAATCACGGCC
CTTCTTCAATATATCCTCATAGTTCTTGGGGTCCATTTGGTCAGTATGGTAATTGTGCAACCGTCATGAAGCGAGCGTTG
AACCTTCATGGTAAGACACTCAGTTCATCAGGCTATTATTCGACCGCCGCTGCTCAGTCTATCCTACCGGAAGTCGTCGG
AGATAGTGAGGTGTATTCAGAGCAGACAACCTTAAGTTACATCGAGGAAGAAACGGATTTACTAATCTTTTGGGCGTGTG
ATCCGATAAAGAATTTAAAAATTGGTTTTGGTACATCAGATCATGCACCTTATGAATACTGGGATAGAATCAAAGCTAAG
GTCGCTTCGGGTAAATTGAAAGTGATTTCTGTTGATCCTGTTAAATCAGAAGCTCAGAAATTTTTAGGTGGAGAGCAATT
AGCAATTAAGCCTCAGACAGATACTGCATTGCTGTTGGGGTTATGTCATGAATTATTGGAAAGTGACCAGTATGACGCTG
ACTTTATCGATACTTATACCGATGGTGCTGATGAGTTGTTCAGTTACCTCAATGGTGAAAAAGATGGAGTCAAAAAGACG
GCTGAGTGGGCGTCGAAGATTTGTGGCGTACCCGTTGAGACGATTAAATCTCTTGCCAAACAGATGGTTTCAGGGCGAAC
TTTGATCAGTAGTGGCTGGAGTGCTCAGCGAGCTCATCATGGCGAGCAATACTGTATGTCAATTGTTTCTCTGGCTTCAA
TGATCGGACAAATCGGACTTCCTGGAGGTGGTTTTTCATTTGGTTACATTTATAACGATGCCGGTGCTGGCTCGTCGAAT
GGTGCCCGTTTAGGATCTTTGTCTGCATCGATTAAAGGAGCTAAACCCAAACATGACAAGCCTTATACGAGTACTCCTTA
TTTCCCCACATCGCGCATAGTTGATGTTATTGAAAATCCAGGAATGAAAAGTACTTATAAAGGAAACGATATTACTTACC
CTGATCTAAGAGTTTTAATTGTTTCAGGGGCTAATATTGTTTCCACTCACCAAGACGTTAACCGATTAACCAAGGCGTTA
GATAAGCTTGATTTTATGGTAACGATCGATACTCAATGGACTGCTACCTGTCGCTATTCAGATTTGGTTTTACCTACTAC
CACTCTTTGGGAGCGTGATGAGCTTTCTGGGTATGGTAATGCAACCAATCGAGGCGTTGTGGGTATGCGTAAGCTTATCG
AGCCAATGTACGATTCTAAAGACGACTTTGATATTTGGCGTATGTTTACTGCTAAGTTTGGTAAAGAGAAGGAATTTACC
GGTGGTAAAACGCAGTTGCAGTGGTTGAAAGAATTTTACGATAAAGCTTATGAGGCCAACCAGAAAAAAGGTATTGAAAT
GCCGACGTTCGAGAGTTTCTGGACAGATAAGACAGCCTTTATTAGATATGAGGGCAATAATAAGTATGTTCGTCACCAGT
CATTCCGCGATGATCCTGATTTGGATGGTCTAGCAACCGACTCTGGCTTAATTCAATTGTTCTCCCAAAAAGTAGCCAAT
GCAAATCTTAAAGATTGTACGCCGTATGCGAGTTGGATTGAGCCCACTGATTGGAAAGAAAGAGTCTCTGGAGAGTATAT
GCACATGGTAACGCTTCATCCTAGTAACCGATTACACTCACAACTCGGCGGAGTTCAGGAGCTGAGGGAGGCGGTTAACA
GCAATGATCATGAACCGATGTGGATCAACCCGTCAGATGGAGCCAAATACGGTATAAAAACCGGCGATATAGTGGAAGGT
TACAATGAAAGAGGCTCTGTTCTGTTCGGTGCGATTATTTCTGATAAAGTGAGTGAAGGGGTGGTTGCTTCGCAAGAGGG
TGGTTGGTATAGCCCTAAGGGAGCTTCTTGTTTGTACGGTAATGCGAACGTCTTGACTAATGACCAAGGGACATCTTCAT
GGGGTCAAGGGCCAACGGCTCAGACATGTTTAGTTAAAGTGAAAAAATACTCGGGTAAAAAGCCTCAAATTGATTGTTTT
ACTGGTCCGATTATTAAATCAAGCTGA

Upstream 100 bases:

>100_bases
ACAAGCTGTTGAAGTACTTACAGTACCACTCTGCTGATTTTGCTAGTAACCATTGATAAATGGACTATTGAACTCATCAC
ATAATGAATAAGGAAAAAAT

Downstream 100 bases:

>100_bases
TTGTAAAGAGTGACACCTCCCATTTACCCTGCTTTCAATTGAGAGCGGGGTTTCATTTTTCTACATCAGGGCGTGATTTT
AAGAAAGGCATTTATTCTGA

Product: trimethylamine-N-oxide reductase 1

Products: NA

Alternate protein names: TMAO reductase; Trimethylamine oxidase [H]

Number of amino acids: Translated: 808; Mature: 808

Protein sequence:

>808_residues
MELSRRSFLKSAGVASTAALSAQLTPLAFAASTDVAIKKALTASKFGTFEATIDNGVITGVSPIDKLGMTIDLAEYAYKT
INNPSRIQTPMVRKGYLEGKGGNRGDNEFVPISWEQAIDLLYNKLEEAQVNHGPSSIYPHSSWGPFGQYGNCATVMKRAL
NLHGKTLSSSGYYSTAAAQSILPEVVGDSEVYSEQTTLSYIEEETDLLIFWACDPIKNLKIGFGTSDHAPYEYWDRIKAK
VASGKLKVISVDPVKSEAQKFLGGEQLAIKPQTDTALLLGLCHELLESDQYDADFIDTYTDGADELFSYLNGEKDGVKKT
AEWASKICGVPVETIKSLAKQMVSGRTLISSGWSAQRAHHGEQYCMSIVSLASMIGQIGLPGGGFSFGYIYNDAGAGSSN
GARLGSLSASIKGAKPKHDKPYTSTPYFPTSRIVDVIENPGMKSTYKGNDITYPDLRVLIVSGANIVSTHQDVNRLTKAL
DKLDFMVTIDTQWTATCRYSDLVLPTTTLWERDELSGYGNATNRGVVGMRKLIEPMYDSKDDFDIWRMFTAKFGKEKEFT
GGKTQLQWLKEFYDKAYEANQKKGIEMPTFESFWTDKTAFIRYEGNNKYVRHQSFRDDPDLDGLATDSGLIQLFSQKVAN
ANLKDCTPYASWIEPTDWKERVSGEYMHMVTLHPSNRLHSQLGGVQELREAVNSNDHEPMWINPSDGAKYGIKTGDIVEG
YNERGSVLFGAIISDKVSEGVVASQEGGWYSPKGASCLYGNANVLTNDQGTSSWGQGPTAQTCLVKVKKYSGKKPQIDCF
TGPIIKSS

Sequences:

>Translated_808_residues
MELSRRSFLKSAGVASTAALSAQLTPLAFAASTDVAIKKALTASKFGTFEATIDNGVITGVSPIDKLGMTIDLAEYAYKT
INNPSRIQTPMVRKGYLEGKGGNRGDNEFVPISWEQAIDLLYNKLEEAQVNHGPSSIYPHSSWGPFGQYGNCATVMKRAL
NLHGKTLSSSGYYSTAAAQSILPEVVGDSEVYSEQTTLSYIEEETDLLIFWACDPIKNLKIGFGTSDHAPYEYWDRIKAK
VASGKLKVISVDPVKSEAQKFLGGEQLAIKPQTDTALLLGLCHELLESDQYDADFIDTYTDGADELFSYLNGEKDGVKKT
AEWASKICGVPVETIKSLAKQMVSGRTLISSGWSAQRAHHGEQYCMSIVSLASMIGQIGLPGGGFSFGYIYNDAGAGSSN
GARLGSLSASIKGAKPKHDKPYTSTPYFPTSRIVDVIENPGMKSTYKGNDITYPDLRVLIVSGANIVSTHQDVNRLTKAL
DKLDFMVTIDTQWTATCRYSDLVLPTTTLWERDELSGYGNATNRGVVGMRKLIEPMYDSKDDFDIWRMFTAKFGKEKEFT
GGKTQLQWLKEFYDKAYEANQKKGIEMPTFESFWTDKTAFIRYEGNNKYVRHQSFRDDPDLDGLATDSGLIQLFSQKVAN
ANLKDCTPYASWIEPTDWKERVSGEYMHMVTLHPSNRLHSQLGGVQELREAVNSNDHEPMWINPSDGAKYGIKTGDIVEG
YNERGSVLFGAIISDKVSEGVVASQEGGWYSPKGASCLYGNANVLTNDQGTSSWGQGPTAQTCLVKVKKYSGKKPQIDCF
TGPIIKSS
>Mature_808_residues
MELSRRSFLKSAGVASTAALSAQLTPLAFAASTDVAIKKALTASKFGTFEATIDNGVITGVSPIDKLGMTIDLAEYAYKT
INNPSRIQTPMVRKGYLEGKGGNRGDNEFVPISWEQAIDLLYNKLEEAQVNHGPSSIYPHSSWGPFGQYGNCATVMKRAL
NLHGKTLSSSGYYSTAAAQSILPEVVGDSEVYSEQTTLSYIEEETDLLIFWACDPIKNLKIGFGTSDHAPYEYWDRIKAK
VASGKLKVISVDPVKSEAQKFLGGEQLAIKPQTDTALLLGLCHELLESDQYDADFIDTYTDGADELFSYLNGEKDGVKKT
AEWASKICGVPVETIKSLAKQMVSGRTLISSGWSAQRAHHGEQYCMSIVSLASMIGQIGLPGGGFSFGYIYNDAGAGSSN
GARLGSLSASIKGAKPKHDKPYTSTPYFPTSRIVDVIENPGMKSTYKGNDITYPDLRVLIVSGANIVSTHQDVNRLTKAL
DKLDFMVTIDTQWTATCRYSDLVLPTTTLWERDELSGYGNATNRGVVGMRKLIEPMYDSKDDFDIWRMFTAKFGKEKEFT
GGKTQLQWLKEFYDKAYEANQKKGIEMPTFESFWTDKTAFIRYEGNNKYVRHQSFRDDPDLDGLATDSGLIQLFSQKVAN
ANLKDCTPYASWIEPTDWKERVSGEYMHMVTLHPSNRLHSQLGGVQELREAVNSNDHEPMWINPSDGAKYGIKTGDIVEG
YNERGSVLFGAIISDKVSEGVVASQEGGWYSPKGASCLYGNANVLTNDQGTSSWGQGPTAQTCLVKVKKYSGKKPQIDCF
TGPIIKSS

Specific function: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787231, Length=830, Percent_Identity=39.0361445783133, Blast_Score=629, Evalue=0.0,
Organism=Escherichia coli, GI87081994, Length=821, Percent_Identity=36.5408038976857, Blast_Score=549, Evalue=1e-157,
Organism=Escherichia coli, GI145693196, Length=776, Percent_Identity=35.4381443298969, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI87081797, Length=752, Percent_Identity=28.8563829787234, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI1787870, Length=753, Percent_Identity=26.6932270916335, Blast_Score=231, Evalue=9e-62,
Organism=Escherichia coli, GI171474008, Length=745, Percent_Identity=25.6375838926174, Blast_Score=215, Evalue=9e-57,
Organism=Escherichia coli, GI3868721, Length=741, Percent_Identity=22.2672064777328, Blast_Score=112, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311
- InterPro:   IPR011887 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 88739; Mature: 88739

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSRRSFLKSAGVASTAALSAQLTPLAFAASTDVAIKKALTASKFGTFEATIDNGVITG
CCCCHHHHHHHCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCEEEC
VSPIDKLGMTIDLAEYAYKTINNPSRIQTPMVRKGYLEGKGGNRGDNEFVPISWEQAIDL
CCCHHHHCCEEEHHHHHHHHCCCCHHHCCCHHHCCCEECCCCCCCCCCEEECCHHHHHHH
LYNKLEEAQVNHGPSSIYPHSSWGPFGQYGNCATVMKRALNLHGKTLSSSGYYSTAAAQS
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHH
ILPEVVGDSEVYSEQTTLSYIEEETDLLIFWACDPIKNLKIGFGTSDHAPYEYWDRIKAK
HHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHH
VASGKLKVISVDPVKSEAQKFLGGEQLAIKPQTDTALLLGLCHELLESDQYDADFIDTYT
HCCCCEEEEEECCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHC
DGADELFSYLNGEKDGVKKTAEWASKICGVPVETIKSLAKQMVSGRTLISSGWSAQRAHH
CCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHC
GEQYCMSIVSLASMIGQIGLPGGGFSFGYIYNDAGAGSSNGARLGSLSASIKGAKPKHDK
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCC
PYTSTPYFPTSRIVDVIENPGMKSTYKGNDITYPDLRVLIVSGANIVSTHQDVNRLTKAL
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
DKLDFMVTIDTQWTATCRYSDLVLPTTTLWERDELSGYGNATNRGVVGMRKLIEPMYDSK
HHCEEEEEEECCEEEEEEECCEECCCHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCC
DDFDIWRMFTAKFGKEKEFTGGKTQLQWLKEFYDKAYEANQKKGIEMPTFESFWTDKTAF
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCCCCCCHHHCCCCEEE
IRYEGNNKYVRHQSFRDDPDLDGLATDSGLIQLFSQKVANANLKDCTPYASWIEPTDWKE
EEECCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHH
RVSGEYMHMVTLHPSNRLHSQLGGVQELREAVNSNDHEPMWINPSDGAKYGIKTGDIVEG
HCCCCEEEEEEECCCHHHHHHHCCHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHCC
YNERGSVLFGAIISDKVSEGVVASQEGGWYSPKGASCLYGNANVLTNDQGTSSWGQGPTA
CCCCCCEEEEHHHHHHHHCCCEECCCCCEECCCCCEEEECCCEEEECCCCCCCCCCCCCH
QTCLVKVKKYSGKKPQIDCFTGPIIKSS
HHHHHHHHHHCCCCCCEEEECCCCCCCC
>Mature Secondary Structure
MELSRRSFLKSAGVASTAALSAQLTPLAFAASTDVAIKKALTASKFGTFEATIDNGVITG
CCCCHHHHHHHCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCEEEC
VSPIDKLGMTIDLAEYAYKTINNPSRIQTPMVRKGYLEGKGGNRGDNEFVPISWEQAIDL
CCCHHHHCCEEEHHHHHHHHCCCCHHHCCCHHHCCCEECCCCCCCCCCEEECCHHHHHHH
LYNKLEEAQVNHGPSSIYPHSSWGPFGQYGNCATVMKRALNLHGKTLSSSGYYSTAAAQS
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCHHHHHHH
ILPEVVGDSEVYSEQTTLSYIEEETDLLIFWACDPIKNLKIGFGTSDHAPYEYWDRIKAK
HHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCCCHHHHHHHHHH
VASGKLKVISVDPVKSEAQKFLGGEQLAIKPQTDTALLLGLCHELLESDQYDADFIDTYT
HCCCCEEEEEECCCHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHC
DGADELFSYLNGEKDGVKKTAEWASKICGVPVETIKSLAKQMVSGRTLISSGWSAQRAHH
CCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEECCCCCHHHHHC
GEQYCMSIVSLASMIGQIGLPGGGFSFGYIYNDAGAGSSNGARLGSLSASIKGAKPKHDK
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCEEECCCCCCCCCCCCCCC
PYTSTPYFPTSRIVDVIENPGMKSTYKGNDITYPDLRVLIVSGANIVSTHQDVNRLTKAL
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHH
DKLDFMVTIDTQWTATCRYSDLVLPTTTLWERDELSGYGNATNRGVVGMRKLIEPMYDSK
HHCEEEEEEECCEEEEEEECCEECCCHHCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCC
DDFDIWRMFTAKFGKEKEFTGGKTQLQWLKEFYDKAYEANQKKGIEMPTFESFWTDKTAF
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCCCCCCHHHCCCCEEE
IRYEGNNKYVRHQSFRDDPDLDGLATDSGLIQLFSQKVANANLKDCTPYASWIEPTDWKE
EEECCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHH
RVSGEYMHMVTLHPSNRLHSQLGGVQELREAVNSNDHEPMWINPSDGAKYGIKTGDIVEG
HCCCCEEEEEEECCCHHHHHHHCCHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCHHCC
YNERGSVLFGAIISDKVSEGVVASQEGGWYSPKGASCLYGNANVLTNDQGTSSWGQGPTA
CCCCCCEEEEHHHHHHHHCCCEECCCCCEECCCCCEEEECCCEEEECCCCCCCCCCCCCH
QTCLVKVKKYSGKKPQIDCFTGPIIKSS
HHHHHHHHHHCCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9813127; 9813128 [H]