Click here to switch to the map view.

The map label for this gene is aroF [H]

Identifier: 156938223

GI number: 156938223

Start: 1292290

End: 1293288

Strand: Reverse

Name: aroF [H]

Synonym: Igni_1436

Alternate gene names: 156938223

Gene position: 1293288-1292290 (Counterclockwise)

Preceding gene: 156938224

Following gene: 156938222

Centisome position: 99.67

GC content: 57.26

Gene sequence:

>999_bases
GTGCTTAAACAAGGCGAGGGCGGATCGGAAGTCAAGAACGTCTTACAAGAGAAGGGCTTGAAGTTCTGGGAAGTCACCTT
ATACGGCCGTCCTCTGATAGTGACCCCTCCCGGGACCTTCGTCGAGGGCTTGGAGAAGTTGCCCGGAGTTGAATTGGTGC
TAAACGTGAAGGCGAAGTACCCGCTGGCGAGCAGGGAGTTCAAACAAGAGGACACGATCGTGAGCATCGGAAACGCTAAG
TTCGGGGGCGAGTACTTCTCCGTAATAGCCGGCCCGTGCTCCGTAGAGAGCGAAGAACAAATACTCTCTACGGCAGAGTT
CGTGAAGAAGGAGGGCGCAGCCGCTCTGAGGGGCGGCGCCTACAAGCCTAGGACTAACCCCTACTCCTTCCAAGGCCTCG
GAGAGGAGGGCTTGAAGCTTTTAAAGAAGGCCAAAGAGGTTACGGGTCTCCCCATAGTCACTGAGGTCATGGACACTAGG
GACGTCCCTAAGGTGGCGGAAGTGGCAGACGCCTTCCAGATAGGGGCCCGGAACATGCAGAACTTCCCGCTGCTCAGAGA
GGTCGGCAAGGCAAAGAAGCCGGTCGTCTTAAAGAGGGGACTGGGCAACACGGTGGAGGAGTGGTTCCAAGCGGCCGAGT
ACGTCTTGTTGGAGGGGAACGGCGACGTGATACTGTGTGAGAGGGGCATAAGGACCTTCGAGACTGCCACCAGGTTCACC
TTGGACGTGGCTGCCATACCGGTAGGCAAGAAGAAGGTCCACTTGCCGGTGATAGGGGACCCCTCCCACCCTGCCGGCAA
GAGGGACTTGGTAGAGCCGTTGGCGCTTGCAATAGTCGCGGCCGGCGCCGACGGTCTGATAGTCGAGGTCCACCCCGAGC
CTGACAAGGCGAAGAGCGACGCAGCCCAGCAGTTAACCTTTGAGCAGTTCAAGGAACTTATGAAGAAAGTGAGGGCTTTA
ACTGAAGTGATGGGGAAGCAGCTCGTTACCGCTTTATAA

Upstream 100 bases:

>100_bases
GTCACGCGACCCCTTCCCCCAATAGTCAGGAAGAAGTGGAAGACGATCAGAAGAAAAGGGATGGGTGTGGGAGGGGAGGG
GGAACGGAAGCATGATAATA

Downstream 100 bases:

>100_bases
AAAGCTAGGCGCACTCCTCGCGGTGCTCAGATGAAGTACAGGGACTTGCTCGTGGCCGAGATAACCCCTGAGATGGAAGG
CCGGCGCGTAAGGGTGGCCG

Product: 3-deoxy-7-phosphoheptulonate synthase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MLKQGEGGSEVKNVLQEKGLKFWEVTLYGRPLIVTPPGTFVEGLEKLPGVELVLNVKAKYPLASREFKQEDTIVSIGNAK
FGGEYFSVIAGPCSVESEEQILSTAEFVKKEGAAALRGGAYKPRTNPYSFQGLGEEGLKLLKKAKEVTGLPIVTEVMDTR
DVPKVAEVADAFQIGARNMQNFPLLREVGKAKKPVVLKRGLGNTVEEWFQAAEYVLLEGNGDVILCERGIRTFETATRFT
LDVAAIPVGKKKVHLPVIGDPSHPAGKRDLVEPLALAIVAAGADGLIVEVHPEPDKAKSDAAQQLTFEQFKELMKKVRAL
TEVMGKQLVTAL

Sequences:

>Translated_332_residues
MLKQGEGGSEVKNVLQEKGLKFWEVTLYGRPLIVTPPGTFVEGLEKLPGVELVLNVKAKYPLASREFKQEDTIVSIGNAK
FGGEYFSVIAGPCSVESEEQILSTAEFVKKEGAAALRGGAYKPRTNPYSFQGLGEEGLKLLKKAKEVTGLPIVTEVMDTR
DVPKVAEVADAFQIGARNMQNFPLLREVGKAKKPVVLKRGLGNTVEEWFQAAEYVLLEGNGDVILCERGIRTFETATRFT
LDVAAIPVGKKKVHLPVIGDPSHPAGKRDLVEPLALAIVAAGADGLIVEVHPEPDKAKSDAAQQLTFEQFKELMKKVRAL
TEVMGKQLVTAL
>Mature_332_residues
MLKQGEGGSEVKNVLQEKGLKFWEVTLYGRPLIVTPPGTFVEGLEKLPGVELVLNVKAKYPLASREFKQEDTIVSIGNAK
FGGEYFSVIAGPCSVESEEQILSTAEFVKKEGAAALRGGAYKPRTNPYSFQGLGEEGLKLLKKAKEVTGLPIVTEVMDTR
DVPKVAEVADAFQIGARNMQNFPLLREVGKAKKPVVLKRGLGNTVEEWFQAAEYVLLEGNGDVILCERGIRTFETATRFT
LDVAAIPVGKKKVHLPVIGDPSHPAGKRDLVEPLALAIVAAGADGLIVEVHPEPDKAKSDAAQQLTFEQFKELMKKVRAL
TEVMGKQLVTAL

Specific function: Catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG2876

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=279, Percent_Identity=26.8817204301075, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006268 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 36050; Mature: 36050

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQGEGGSEVKNVLQEKGLKFWEVTLYGRPLIVTPPGTFVEGLEKLPGVELVLNVKAKY
CCCCCCCHHHHHHHHHHCCCEEEEEEEECCEEEECCCCHHHHHHHHCCCEEEEEEECCCC
PLASREFKQEDTIVSIGNAKFGGEYFSVIAGPCSVESEEQILSTAEFVKKEGAAALRGGA
CCCHHHHCCCCCEEEECCCCCCCHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHCCCC
YKPRTNPYSFQGLGEEGLKLLKKAKEVTGLPIVTEVMDTRDVPKVAEVADAFQIGARNMQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
NFPLLREVGKAKKPVVLKRGLGNTVEEWFQAAEYVLLEGNGDVILCERGIRTFETATRFT
CCHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCEEEEECCCCEEEECCCCHHHHHHHHEE
LDVAAIPVGKKKVHLPVIGDPSHPAGKRDLVEPLALAIVAAGADGLIVEVHPEPDKAKSD
EEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
AAQQLTFEQFKELMKKVRALTEVMGKQLVTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKQGEGGSEVKNVLQEKGLKFWEVTLYGRPLIVTPPGTFVEGLEKLPGVELVLNVKAKY
CCCCCCCHHHHHHHHHHCCCEEEEEEEECCEEEECCCCHHHHHHHHCCCEEEEEEECCCC
PLASREFKQEDTIVSIGNAKFGGEYFSVIAGPCSVESEEQILSTAEFVKKEGAAALRGGA
CCCHHHHCCCCCEEEECCCCCCCHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHCCCC
YKPRTNPYSFQGLGEEGLKLLKKAKEVTGLPIVTEVMDTRDVPKVAEVADAFQIGARNMQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCC
NFPLLREVGKAKKPVVLKRGLGNTVEEWFQAAEYVLLEGNGDVILCERGIRTFETATRFT
CCHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCEEEEECCCCEEEECCCCHHHHHHHHEE
LDVAAIPVGKKKVHLPVIGDPSHPAGKRDLVEPLALAIVAAGADGLIVEVHPEPDKAKSD
EEEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHH
AAQQLTFEQFKELMKKVRALTEVMGKQLVTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571; 12743122 [H]