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The map label for this gene is aspC [H]

Identifier: 156938222

GI number: 156938222

Start: 1290898

End: 1292259

Strand: Reverse

Name: aspC [H]

Synonym: Igni_1435

Alternate gene names: 156938222

Gene position: 1292259-1290898 (Counterclockwise)

Preceding gene: 156938223

Following gene: 156938221

Centisome position: 99.59

GC content: 55.58

Gene sequence:

>1362_bases
ATGAAGTACAGGGACTTGCTCGTGGCCGAGATAACCCCTGAGATGGAAGGCCGGCGCGTAAGGGTGGCCGGCTGGGTTCA
CGCGGTCAGAAGCATCGGCAAGCTAGCTTTCCTAATTCTGCGAGACTTCAGCGGCACGATACAAGTTACTTTCAGGGTCC
CGAAGGACGTCAGCGAGGAGGAGAAGAAGAGGTATAAGGAACTAATCAAAAAAGTGAGCAAGATCCCGCCGGAGAGCGTA
GTTATGGTGGTCGGCGTAGTTAGGAGGGACCCCAGGGCCCCAAGAGGCGTGGAACTCAGCGGGGAGGAAATAGAAGTTCT
AAACGAAGCCAAGAGTCCCTTGCCCTTAGACGTATCGGGCAAGGTCGACGCACACATCGACACCAGGCTGGCCAACAGGC
CGATCGACCTCAGGAGGCCCGAGAGCCAAGCGGTGTTGAGGCTGGTCTCACTGAGCGCCAAGGCTATAAGAGAATACTTG
TACAGTTTAAACTTCGTCGAGGTGTTCACCCCTAAGATAATAGCCTCCGGAACCGAAGGCGGGGCCCAACTGGTCCCGGT
CTTCTACTTTGGCAAGACGGCTTACTTAGCCCAAAGCCCCCAGCTCTACAAAGAGCTGCTGACCTCCTCGCTGGAGTACG
TTTTCGAAATAGCTCCCGCGTGGCGTCACGAGGAGAGCGACACCCCCTACCACCTAGCGGAGTTCATTTCTGTTGACGTA
GAAATGGCGTTCGCGGACTACAACGACGTGATGAAAGTCTTAGAAAACGTCGTGAAGAGGGTAATTGACAGCGTTAAGAA
TGAGGGTAGGAAGTGGTTGGAGGTATTGGGCCACGAGCCCCCTGAGGTGAACCTCCCAATACCTCGAATAACCTACAAGG
AGGCTTGGGAAATATTGAAGGCTGAGGGCGTGGAAGTGGAGCCGGGAGAGGACTTCGGCACGCCCGAGCTGAGGAAGTTG
AGCGAGGCGTTGGAAAGGGAGGGCAAGACCTCTGGGGGCTTCTATTTCATAACCGACTGGCCCGCCGACGTGAGGCCTTT
CTACACAAAGAGGGGAGGCAAGGAGGTCATAGGCGGGAAGGAGGTAGACTTGAGCGAGAGCTTCGACTTGAACTGGCGTC
ACCTAGAGATCTCCAGCGGGAGTACGAGAATTCACAGAAGGAACGAGCTAGAGGAGGAGTTAAAGAAGAGAGGCTTGAAC
CCGGCTAACTTCGAATGGTACTTAAAGTGGTACGACTACGGGATGCCCCCGCACGCCGGTTGGGGAATGGGACTCCAAAG
GCTAATGGTCCCGGTAGCTGGGATACCCAACGTGAGGCTCGCCAGCACCTTCCCGAGGGATATGAAGCGCTTGGTGCCAT
AA

Upstream 100 bases:

>100_bases
CAAGGAACTTATGAAGAAAGTGAGGGCTTTAACTGAAGTGATGGGGAAGCAGCTCGTTACCGCTTTATAAAAAGCTAGGC
GCACTCCTCGCGGTGCTCAG

Downstream 100 bases:

>100_bases
GTTTATAAGAGGTTCCGTTAAGCGCCCCCCGGGCGGCGGTCGTCTAGCCTGGACTAGGATGCCGGCCTTCCAAGCCGGTG
ATCCCGGGTTCAAATCCCGG

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MKYRDLLVAEITPEMEGRRVRVAGWVHAVRSIGKLAFLILRDFSGTIQVTFRVPKDVSEEEKKRYKELIKKVSKIPPESV
VMVVGVVRRDPRAPRGVELSGEEIEVLNEAKSPLPLDVSGKVDAHIDTRLANRPIDLRRPESQAVLRLVSLSAKAIREYL
YSLNFVEVFTPKIIASGTEGGAQLVPVFYFGKTAYLAQSPQLYKELLTSSLEYVFEIAPAWRHEESDTPYHLAEFISVDV
EMAFADYNDVMKVLENVVKRVIDSVKNEGRKWLEVLGHEPPEVNLPIPRITYKEAWEILKAEGVEVEPGEDFGTPELRKL
SEALEREGKTSGGFYFITDWPADVRPFYTKRGGKEVIGGKEVDLSESFDLNWRHLEISSGSTRIHRRNELEEELKKRGLN
PANFEWYLKWYDYGMPPHAGWGMGLQRLMVPVAGIPNVRLASTFPRDMKRLVP

Sequences:

>Translated_453_residues
MKYRDLLVAEITPEMEGRRVRVAGWVHAVRSIGKLAFLILRDFSGTIQVTFRVPKDVSEEEKKRYKELIKKVSKIPPESV
VMVVGVVRRDPRAPRGVELSGEEIEVLNEAKSPLPLDVSGKVDAHIDTRLANRPIDLRRPESQAVLRLVSLSAKAIREYL
YSLNFVEVFTPKIIASGTEGGAQLVPVFYFGKTAYLAQSPQLYKELLTSSLEYVFEIAPAWRHEESDTPYHLAEFISVDV
EMAFADYNDVMKVLENVVKRVIDSVKNEGRKWLEVLGHEPPEVNLPIPRITYKEAWEILKAEGVEVEPGEDFGTPELRKL
SEALEREGKTSGGFYFITDWPADVRPFYTKRGGKEVIGGKEVDLSESFDLNWRHLEISSGSTRIHRRNELEEELKKRGLN
PANFEWYLKWYDYGMPPHAGWGMGLQRLMVPVAGIPNVRLASTFPRDMKRLVP
>Mature_453_residues
MKYRDLLVAEITPEMEGRRVRVAGWVHAVRSIGKLAFLILRDFSGTIQVTFRVPKDVSEEEKKRYKELIKKVSKIPPESV
VMVVGVVRRDPRAPRGVELSGEEIEVLNEAKSPLPLDVSGKVDAHIDTRLANRPIDLRRPESQAVLRLVSLSAKAIREYL
YSLNFVEVFTPKIIASGTEGGAQLVPVFYFGKTAYLAQSPQLYKELLTSSLEYVFEIAPAWRHEESDTPYHLAEFISVDV
EMAFADYNDVMKVLENVVKRVIDSVKNEGRKWLEVLGHEPPEVNLPIPRITYKEAWEILKAEGVEVEPGEDFGTPELRKL
SEALEREGKTSGGFYFITDWPADVRPFYTKRGGKEVIGGKEVDLSESFDLNWRHLEISSGSTRIHRRNELEEELKKRGLN
PANFEWYLKWYDYGMPPHAGWGMGLQRLMVPVAGIPNVRLASTFPRDMKRLVP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI45439306, Length=472, Percent_Identity=35.8050847457627, Blast_Score=255, Evalue=7e-68,
Organism=Homo sapiens, GI4758762, Length=451, Percent_Identity=29.7117516629712, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI226491502, Length=480, Percent_Identity=27.0833333333333, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI40789249, Length=263, Percent_Identity=34.2205323193916, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI5031815, Length=473, Percent_Identity=28.3298097251586, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI194272210, Length=473, Percent_Identity=28.3298097251586, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1787161, Length=480, Percent_Identity=26.875, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788173, Length=291, Percent_Identity=29.553264604811, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790571, Length=460, Percent_Identity=23.0434782608696, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1789256, Length=469, Percent_Identity=24.3070362473348, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17551876, Length=477, Percent_Identity=34.3815513626834, Blast_Score=257, Evalue=7e-69,
Organism=Caenorhabditis elegans, GI71984122, Length=446, Percent_Identity=30.2690582959641, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17556372, Length=423, Percent_Identity=25.0591016548463, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI32566633, Length=306, Percent_Identity=32.3529411764706, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71994340, Length=472, Percent_Identity=24.7881355932203, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17535925, Length=472, Percent_Identity=24.7881355932203, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17535927, Length=472, Percent_Identity=24.7881355932203, Blast_Score=82, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6323011, Length=456, Percent_Identity=34.6491228070175, Blast_Score=228, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6321807, Length=447, Percent_Identity=29.9776286353468, Blast_Score=185, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6319872, Length=479, Percent_Identity=25.8872651356994, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320242, Length=493, Percent_Identity=24.1379310344828, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325153, Length=305, Percent_Identity=30.4918032786885, Blast_Score=76, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17136276, Length=476, Percent_Identity=33.8235294117647, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI19921528, Length=449, Percent_Identity=30.5122494432071, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI19922416, Length=479, Percent_Identity=25.0521920668058, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI24584738, Length=301, Percent_Identity=33.5548172757475, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24640849, Length=479, Percent_Identity=26.5135699373695, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24640851, Length=479, Percent_Identity=26.5135699373695, Blast_Score=96, Evalue=7e-20,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020780
- InterPro:   IPR004523
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.12 [H]

Molecular weight: Translated: 51605; Mature: 51605

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYRDLLVAEITPEMEGRRVRVAGWVHAVRSIGKLAFLILRDFSGTIQVTFRVPKDVSEE
CCCHHEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHH
EKKRYKELIKKVSKIPPESVVMVVGVVRRDPRAPRGVELSGEEIEVLNEAKSPLPLDVSG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
KVDAHIDTRLANRPIDLRRPESQAVLRLVSLSAKAIREYLYSLNFVEVFTPKIIASGTEG
CCCCEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHEECCCCC
GAQLVPVFYFGKTAYLAQSPQLYKELLTSSLEYVFEIAPAWRHEESDTPYHLAEFISVDV
CCEEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
EMAFADYNDVMKVLENVVKRVIDSVKNEGRKWLEVLGHEPPEVNLPIPRITYKEAWEILK
HEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
AEGVEVEPGEDFGTPELRKLSEALEREGKTSGGFYFITDWPADVRPFYTKRGGKEVIGGK
HCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCC
EVDLSESFDLNWRHLEISSGSTRIHRRNELEEELKKRGLNPANFEWYLKWYDYGMPPHAG
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCC
WGMGLQRLMVPVAGIPNVRLASTFPRDMKRLVP
HHHHHHHHHHHHCCCCCCEECCCCHHHHHHHCC
>Mature Secondary Structure
MKYRDLLVAEITPEMEGRRVRVAGWVHAVRSIGKLAFLILRDFSGTIQVTFRVPKDVSEE
CCCHHEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHH
EKKRYKELIKKVSKIPPESVVMVVGVVRRDPRAPRGVELSGEEIEVLNEAKSPLPLDVSG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
KVDAHIDTRLANRPIDLRRPESQAVLRLVSLSAKAIREYLYSLNFVEVFTPKIIASGTEG
CCCCEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHEECCCCC
GAQLVPVFYFGKTAYLAQSPQLYKELLTSSLEYVFEIAPAWRHEESDTPYHLAEFISVDV
CCEEEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
EMAFADYNDVMKVLENVVKRVIDSVKNEGRKWLEVLGHEPPEVNLPIPRITYKEAWEILK
HEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
AEGVEVEPGEDFGTPELRKLSEALEREGKTSGGFYFITDWPADVRPFYTKRGGKEVIGGK
HCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCC
EVDLSESFDLNWRHLEISSGSTRIHRRNELEEELKKRGLNPANFEWYLKWYDYGMPPHAG
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCC
WGMGLQRLMVPVAGIPNVRLASTFPRDMKRLVP
HHHHHHHHHHHHCCCCCCEECCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]