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The map label for this gene is truD [H]

Identifier: 156938047

GI number: 156938047

Start: 1122712

End: 1123749

Strand: Reverse

Name: truD [H]

Synonym: Igni_1260

Alternate gene names: 156938047

Gene position: 1123749-1122712 (Counterclockwise)

Preceding gene: 156938048

Following gene: 156938041

Centisome position: 86.61

GC content: 59.83

Gene sequence:

>1038_bases
ATGAGGCGCCCGCACCCCATAGACTATTACGTCGGTATGACGAAGTATTTCCTAAATTTAGAAGCTTGCGAGGGAAGGGT
CCTCAGGCCCAAGGGGTTCCGGGTCATAGAGCTCTCGGAGCCCTCCCCGGGCCCCTCCTACGTATACCTACTCCTCAAGG
AGGGGATAGACACCATCCACGCCCTCCGGGAAATTAGGAGGCGCTTGGGCGGTAAGTGGTACCACTTAGGCCTCAAGGAC
GCTAACGGCGTTACGTTACAGCTCTTGAGCTCGGACGTCGTCAGCGAAGGCCTTCAGCTGAGGCTTAGGAAGGGCTGCCT
GGTCTTGACTCCGTTGGGCAGGGGCTCAATCAACAAGGCCCGCATGTGGGGCAACGCGTTCGTGATAGACCTTCAGTGCT
CCAAACCACACTCGCTCGAAGGGAAAGTGAAGGTCCCGGGCTACTTCTCGTACCAGCGCTTCGGCACCGCTAGGCCGGTC
TCCCACGTGGTGGGCAAGATGATCCTCTTGGAGAGGTGGGAGGAGGCGGTGGAGGCCCTCTTGGGCGAGCCCACCCCGTG
GGAGTCGGAGGCGGCCAGGAGGGTTAGGCTAGAGTATTATTCTGAGGGGCCGCGCGCTTACTTGAGGGCCCCCAAGTTCA
TGGACGTTGAGAGGAGGGTGGCCTTCGAGCTCTTGAGGGGGAGCTCCCCCAAGAGGGCCTTGAAGAAGAGCGGCTTGACG
GAGCTCTTCCTCCACGCCTACCAGTCCTACCTGTACAACAAGAGGCTCTCCGAGTTCGACGACCCTTGTGAGGGCCCCGA
AGCCCTTCCCGGGCCCGGGGCGGAGGGCTACGAAGAGCTCTTAGAGGAGGAAGGGGTTACCTTGGAGCTCTTCAAAAAGT
TCGGCCTGAGGGCGGCCCCTAGGCGACCTTGTTACGAGACCTACGTGAAGAGCTTTGCTAGGGGGGACGGGAGGGTGACG
CTTATCTTCAAGTTGCCTAGGGGCTACTACGCGACGTCTTTATTGAGAGAAATAGTTAGGGACCCCTTCGCCGTCTGA

Upstream 100 bases:

>100_bases
CGAAGGTGCTCGAGGCGATAAGGCAAGCGGGCTTGGAGGAGTTCATGAAGGAGGAAGTAAAGCCGGAGCTGCCGGTACCC
CCGTCCCTCGGAGCTTACCT

Downstream 100 bases:

>100_bases
CTCACTCCGCCACGGGCCCTATTACGGTCTTACCCACCAACTTGTTTATGGTCTCCACGTACTCGTCTACAATCTCTTGC
AGCTTCTTTATTTGTTCCTC

Product: tRNA pseudouridine synthase D, TruD

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D; tRNA-uridine isomerase D [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MRRPHPIDYYVGMTKYFLNLEACEGRVLRPKGFRVIELSEPSPGPSYVYLLLKEGIDTIHALREIRRRLGGKWYHLGLKD
ANGVTLQLLSSDVVSEGLQLRLRKGCLVLTPLGRGSINKARMWGNAFVIDLQCSKPHSLEGKVKVPGYFSYQRFGTARPV
SHVVGKMILLERWEEAVEALLGEPTPWESEAARRVRLEYYSEGPRAYLRAPKFMDVERRVAFELLRGSSPKRALKKSGLT
ELFLHAYQSYLYNKRLSEFDDPCEGPEALPGPGAEGYEELLEEEGVTLELFKKFGLRAAPRRPCYETYVKSFARGDGRVT
LIFKLPRGYYATSLLREIVRDPFAV

Sequences:

>Translated_345_residues
MRRPHPIDYYVGMTKYFLNLEACEGRVLRPKGFRVIELSEPSPGPSYVYLLLKEGIDTIHALREIRRRLGGKWYHLGLKD
ANGVTLQLLSSDVVSEGLQLRLRKGCLVLTPLGRGSINKARMWGNAFVIDLQCSKPHSLEGKVKVPGYFSYQRFGTARPV
SHVVGKMILLERWEEAVEALLGEPTPWESEAARRVRLEYYSEGPRAYLRAPKFMDVERRVAFELLRGSSPKRALKKSGLT
ELFLHAYQSYLYNKRLSEFDDPCEGPEALPGPGAEGYEELLEEEGVTLELFKKFGLRAAPRRPCYETYVKSFARGDGRVT
LIFKLPRGYYATSLLREIVRDPFAV
>Mature_345_residues
MRRPHPIDYYVGMTKYFLNLEACEGRVLRPKGFRVIELSEPSPGPSYVYLLLKEGIDTIHALREIRRRLGGKWYHLGLKD
ANGVTLQLLSSDVVSEGLQLRLRKGCLVLTPLGRGSINKARMWGNAFVIDLQCSKPHSLEGKVKVPGYFSYQRFGTARPV
SHVVGKMILLERWEEAVEALLGEPTPWESEAARRVRLEYYSEGPRAYLRAPKFMDVERRVAFELLRGSSPKRALKKSGLT
ELFLHAYQSYLYNKRLSEFDDPCEGPEALPGPGAEGYEELLEEEGVTLELFKKFGLRAAPRRPCYETYVKSFARGDGRVT
LIFKLPRGYYATSLLREIVRDPFAV

Specific function: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

Organism=Homo sapiens, GI50727002, Length=272, Percent_Identity=27.5735294117647, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 39323; Mature: 39323

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS50984 TRUD ; PS00213 LIPOCALIN ; PS01268 UPF0024

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPHPIDYYVGMTKYFLNLEACEGRVLRPKGFRVIELSEPSPGPSYVYLLLKEGIDTIH
CCCCCCCHHHHHHHHHHEEHHHCCCEEECCCCCEEEEECCCCCCCCEEEHHHHHCHHHHH
ALREIRRRLGGKWYHLGLKDANGVTLQLLSSDVVSEGLQLRLRKGCLVLTPLGRGSINKA
HHHHHHHHHCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHH
RMWGNAFVIDLQCSKPHSLEGKVKVPGYFSYQRFGTARPVSHVVGKMILLERWEEAVEAL
EECCCEEEEEEECCCCCCCCCEEECCCEECHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LGEPTPWESEAARRVRLEYYSEGPRAYLRAPKFMDVERRVAFELLRGSSPKRALKKSGLT
HCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCHH
ELFLHAYQSYLYNKRLSEFDDPCEGPEALPGPGAEGYEELLEEEGVTLELFKKFGLRAAP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEHHHHHHCCCCCC
RRPCYETYVKSFARGDGRVTLIFKLPRGYYATSLLREIVRDPFAV
CCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRRPHPIDYYVGMTKYFLNLEACEGRVLRPKGFRVIELSEPSPGPSYVYLLLKEGIDTIH
CCCCCCCHHHHHHHHHHEEHHHCCCEEECCCCCEEEEECCCCCCCCEEEHHHHHCHHHHH
ALREIRRRLGGKWYHLGLKDANGVTLQLLSSDVVSEGLQLRLRKGCLVLTPLGRGSINKA
HHHHHHHHHCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHH
RMWGNAFVIDLQCSKPHSLEGKVKVPGYFSYQRFGTARPVSHVVGKMILLERWEEAVEAL
EECCCEEEEEEECCCCCCCCCEEECCCEECHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LGEPTPWESEAARRVRLEYYSEGPRAYLRAPKFMDVERRVAFELLRGSSPKRALKKSGLT
HCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCHH
ELFLHAYQSYLYNKRLSEFDDPCEGPEALPGPGAEGYEELLEEEGVTLELFKKFGLRAAP
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEHHHHHHCCCCCC
RRPCYETYVKSFARGDGRVTLIFKLPRGYYATSLLREIVRDPFAV
CCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]