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The map label for this gene is 156937987

Identifier: 156937987

GI number: 156937987

Start: 1069415

End: 1070452

Strand: Reverse

Name: 156937987

Synonym: Igni_1200

Alternate gene names: NA

Gene position: 1070452-1069415 (Counterclockwise)

Preceding gene: 156937988

Following gene: 156937986

Centisome position: 82.5

GC content: 61.56

Gene sequence:

>1038_bases
TTGGAAAGGGCAATTTACGTGGGTGACGTGTTCCTCTTACACAAGACCCCTCCCGGGCACCCGGAGAGCCCGGAGAGGGT
AAAGGCTATCTTAGATTTGATGAAAAGGACCAAGCTCCCGAATTACGTCGAAGTGAGAAGTCCAGTCCCTATAGACGAAA
GGGAGTTGGAGTTAGTTCACGATAGGGATTACGTCGAGTACGTAAAGAGGGTCATAGAGGCCGGAGGGGGCTACTTGGAC
CCAGACACCTACGCCAGCCCCACCTCCTGGGAGCCGGCCCTCTACGCCGCCGGCACGGTGGCTTACGCAGCTCAGAGGGC
AGTGGAGGGCGACCACTGGCTCGCGTTCGCGGCCGTCAGGCCGCCCGGCCACCACGCCCGGAGGTCCGAAGGCAGGGGGT
TCTGTATATTCAACAACGTCGCCTTGGCCGCCGAGGTCTTGAGGAGGAGGGGGATGAGGGTCGCCGTCGTGGACATAGAC
GTCCACTGGGGCGACGGGACGGCTTACATATTCTACAACACCGACGAGGTCCTCTACGTCAGCACACACCAAGACCCTAG
GACCCTCTATCCCTTCGAGGGCTTCCCCAGCCAGAAGGGCTCCGGTAAGGGGGAGGGCTACACCGTCAACGTCCCCTTGC
CCCCGGGCACTGGGGACAAGGGCTTCTTGTACGCCCTCCACGAAGTGGTCTTGCCGGTGCTCGAGGCTTACTTGCCCCAA
GCGCTCTTGGTCTCCGCCGGCTGGGACACCCACTGGCTCGACCCCTTGGCGTCCCTCGAGGTTACTGTGGACGGCCACTG
GGAGGCCGTCAGCTCCCTCGCGAGCTTCGCGGAGAGCTTGGGGATCCCCATAGTCATAGCATTGGAGGGGGGCTACGTGA
ATTGGGTCGTAGCGAGGAGTACGTTAAACTCCCTTGGGGCCGCTAAGGAGAAGTTCTTCGGTGACGAGGAGAGGGTCGTG
GATAGCGTTCCGGAGGAAGAGGTGGAGTTCTACGTGGAGGAGGCCAAGAGGGAGCTGAGGGGGTACTGGCCCCTCTGA

Upstream 100 bases:

>100_bases
AGCTTACAGCGAGGAGGCCTTCTGGCCTTCAATAGCCACCACCACCTTCCTGGTCGTCGGCTAAAACCCCCCTTTTTTCC
GCCCGTAAAGGGCACAACTC

Downstream 100 bases:

>100_bases
GGCCTTTAGGTGGTGCCGGGGGTGGGATTTGAACCCACGCAGGCCTACGCCAGCGGGTCTTAAGCCCGCCCCCTTTTCCG
GGCTCGGGCACCCCGGCTCC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MERAIYVGDVFLLHKTPPGHPESPERVKAILDLMKRTKLPNYVEVRSPVPIDERELELVHDRDYVEYVKRVIEAGGGYLD
PDTYASPTSWEPALYAAGTVAYAAQRAVEGDHWLAFAAVRPPGHHARRSEGRGFCIFNNVALAAEVLRRRGMRVAVVDID
VHWGDGTAYIFYNTDEVLYVSTHQDPRTLYPFEGFPSQKGSGKGEGYTVNVPLPPGTGDKGFLYALHEVVLPVLEAYLPQ
ALLVSAGWDTHWLDPLASLEVTVDGHWEAVSSLASFAESLGIPIVIALEGGYVNWVVARSTLNSLGAAKEKFFGDEERVV
DSVPEEEVEFYVEEAKRELRGYWPL

Sequences:

>Translated_345_residues
MERAIYVGDVFLLHKTPPGHPESPERVKAILDLMKRTKLPNYVEVRSPVPIDERELELVHDRDYVEYVKRVIEAGGGYLD
PDTYASPTSWEPALYAAGTVAYAAQRAVEGDHWLAFAAVRPPGHHARRSEGRGFCIFNNVALAAEVLRRRGMRVAVVDID
VHWGDGTAYIFYNTDEVLYVSTHQDPRTLYPFEGFPSQKGSGKGEGYTVNVPLPPGTGDKGFLYALHEVVLPVLEAYLPQ
ALLVSAGWDTHWLDPLASLEVTVDGHWEAVSSLASFAESLGIPIVIALEGGYVNWVVARSTLNSLGAAKEKFFGDEERVV
DSVPEEEVEFYVEEAKRELRGYWPL
>Mature_345_residues
MERAIYVGDVFLLHKTPPGHPESPERVKAILDLMKRTKLPNYVEVRSPVPIDERELELVHDRDYVEYVKRVIEAGGGYLD
PDTYASPTSWEPALYAAGTVAYAAQRAVEGDHWLAFAAVRPPGHHARRSEGRGFCIFNNVALAAEVLRRRGMRVAVVDID
VHWGDGTAYIFYNTDEVLYVSTHQDPRTLYPFEGFPSQKGSGKGEGYTVNVPLPPGTGDKGFLYALHEVVLPVLEAYLPQ
ALLVSAGWDTHWLDPLASLEVTVDGHWEAVSSLASFAESLGIPIVIALEGGYVNWVVARSTLNSLGAAKEKFFGDEERVV
DSVPEEEVEFYVEEAKRELRGYWPL

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=287, Percent_Identity=34.8432055749129, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI17158039, Length=306, Percent_Identity=32.6797385620915, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI30795204, Length=306, Percent_Identity=32.6797385620915, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI30795202, Length=306, Percent_Identity=32.6797385620915, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI20070354, Length=318, Percent_Identity=33.3333333333333, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI148539870, Length=321, Percent_Identity=31.7757009345794, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI169234807, Length=321, Percent_Identity=31.7757009345794, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI153085395, Length=375, Percent_Identity=29.6, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI13128860, Length=302, Percent_Identity=29.1390728476821, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI13128862, Length=290, Percent_Identity=27.5862068965517, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI62750347, Length=232, Percent_Identity=37.5, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI62750349, Length=232, Percent_Identity=37.5, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI226529806, Length=235, Percent_Identity=35.3191489361702, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI293336691, Length=278, Percent_Identity=28.4172661870504, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI8923769, Length=252, Percent_Identity=30.1587301587302, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI262073088, Length=139, Percent_Identity=36.6906474820144, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI262073092, Length=212, Percent_Identity=30.188679245283, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI209862883, Length=295, Percent_Identity=24.7457627118644, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI217272877, Length=301, Percent_Identity=24.5847176079734, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=294, Percent_Identity=34.3537414965986, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17540332, Length=294, Percent_Identity=34.3537414965986, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI193206283, Length=296, Percent_Identity=34.1216216216216, Blast_Score=150, Evalue=9e-37,
Organism=Caenorhabditis elegans, GI193209491, Length=266, Percent_Identity=34.9624060150376, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17534739, Length=290, Percent_Identity=30.6896551724138, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17537347, Length=296, Percent_Identity=34.1216216216216, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17508561, Length=313, Percent_Identity=28.4345047923323, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17561978, Length=304, Percent_Identity=28.6184210526316, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI25154020, Length=284, Percent_Identity=28.8732394366197, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI25154022, Length=285, Percent_Identity=28.4210526315789, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324307, Length=316, Percent_Identity=30.6962025316456, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6323999, Length=293, Percent_Identity=30.3754266211604, Blast_Score=129, Evalue=8e-31,
Organism=Saccharomyces cerevisiae, GI6321244, Length=291, Percent_Identity=26.4604810996564, Blast_Score=110, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6325325, Length=240, Percent_Identity=25.8333333333333, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281360899, Length=311, Percent_Identity=35.3697749196142, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24642146, Length=311, Percent_Identity=35.3697749196142, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24642144, Length=311, Percent_Identity=35.3697749196142, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24642142, Length=311, Percent_Identity=35.3697749196142, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI281360799, Length=305, Percent_Identity=32.1311475409836, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI281360801, Length=305, Percent_Identity=32.1311475409836, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24641720, Length=305, Percent_Identity=32.1311475409836, Blast_Score=134, Evalue=9e-32,
Organism=Drosophila melanogaster, GI24657891, Length=302, Percent_Identity=28.1456953642384, Blast_Score=117, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24644244, Length=294, Percent_Identity=26.530612244898, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 38382; Mature: 38382

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERAIYVGDVFLLHKTPPGHPESPERVKAILDLMKRTKLPNYVEVRSPVPIDERELELVH
CCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHEEC
DRDYVEYVKRVIEAGGGYLDPDTYASPTSWEPALYAAGTVAYAAQRAVEGDHWLAFAAVR
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEC
PPGHHARRSEGRGFCIFNNVALAAEVLRRRGMRVAVVDIDVHWGDGTAYIFYNTDEVLYV
CCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCEEEEEEEEEEECCCEEEEEECCCEEEEE
STHQDPRTLYPFEGFPSQKGSGKGEGYTVNVPLPPGTGDKGFLYALHEVVLPVLEAYLPQ
EECCCCCEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
ALLVSAGWDTHWLDPLASLEVTVDGHWEAVSSLASFAESLGIPIVIALEGGYVNWVVARS
EEEEECCCCCHHCCCHHEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEHH
TLNSLGAAKEKFFGDEERVVDSVPEEEVEFYVEEAKRELRGYWPL
HHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MERAIYVGDVFLLHKTPPGHPESPERVKAILDLMKRTKLPNYVEVRSPVPIDERELELVH
CCCEEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHEEC
DRDYVEYVKRVIEAGGGYLDPDTYASPTSWEPALYAAGTVAYAAQRAVEGDHWLAFAAVR
CCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEC
PPGHHARRSEGRGFCIFNNVALAAEVLRRRGMRVAVVDIDVHWGDGTAYIFYNTDEVLYV
CCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCEEEEEEEEEEECCCEEEEEECCCEEEEE
STHQDPRTLYPFEGFPSQKGSGKGEGYTVNVPLPPGTGDKGFLYALHEVVLPVLEAYLPQ
EECCCCCEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
ALLVSAGWDTHWLDPLASLEVTVDGHWEAVSSLASFAESLGIPIVIALEGGYVNWVVARS
EEEEECCCCCHHCCCHHEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEEHH
TLNSLGAAKEKFFGDEERVVDSVPEEEVEFYVEEAKRELRGYWPL
HHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]