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The map label for this gene is secY [H]

Identifier: 156937986

GI number: 156937986

Start: 1067813

End: 1069252

Strand: Reverse

Name: secY [H]

Synonym: Igni_1199

Alternate gene names: 156937986

Gene position: 1069252-1067813 (Counterclockwise)

Preceding gene: 156937987

Following gene: 156937985

Centisome position: 82.41

GC content: 58.13

Gene sequence:

>1440_bases
GTGCAAGACCTAGGGCGCAAGGCTTTGGAAGTGCTGGCGGAAATTGGGACCTACGTCCCGGCTGTCCCTCGGCCTAAGAG
AAAGATAAACTTGTACAAGAGGCTCACGTGGACCGCCCTCGCTTTGGTTGCTTACCTAATGATGAGCAACATACCTCTGC
CCGGCGTGAGCGTGCAGACGAGCTTCAACCTCCTCTTGATGAACATAGTGTTCGCGGCCAACGCGGGCACACTGATGCAG
TTGGGAATAGGGCCCATAGTGACCGCCGGCCTGGTCTTGCAGCTGTTGGTGGGAGCGAAAATAATAGACTTGGACCTGAC
CGACCCAGAAGATAAGAAGCTGTTCACATTGGCACAGAAGGGCTTCGCGGTAGTGCTGGCCGTGTTCGAGGCAATCGGCT
TGGTCCTCTCCGGGAGCCTCTGGACCACTGTGACCCCCGACGGGGTGGTGGTTTACAACCCTCCCCCCGCGCCGGTGATA
GTCCTCGACATGTTGCTGTTGGCGGGCGCCACTATACTGGTAATAATTATGGACGAGATGATCCAGAAGGGCTACGGCCT
GGGGAGCGGGATAAGCTTGTTCATAGCTGCCAGCGTGGTCAGCGGGATAGCTTGGGAGTTCGCGGGCTGGTTCAGCCAAG
CCGGTCAGCTCATCTGGGCCGGCCTGGTGCCTGCGGCGCTCAAGTGCGGCCTCGCCTCCGTAATACTGGGCAACCCCCTC
GGCGCCCCCAAGGTCCCCGGGACCCAAGTGGTCTGCGACGGCCGGAGAGTCCCGGTGGGGGCGATGCCGGACCTAATAGG
CTTCTTAGCCACCGTTGTTATGATAGCCGCCATAGCCTACTTGAGCTCAGTTAAGATCCAAGTACCCCTCGTGGTAAAGG
AGATGAGGGGGATGAGGATAAAGATACCCCTCAACTTGCTCTACGTCACAAACATACCGGTCTTGTTGGCAGCAATAATA
TTCGCTAACATACAGACCGTCGCTTCCCACGCCCCCGGGAGCCCGCTCTCCGCGGTGGCCTACTACTTGACCCCTCCAAG
GGGGCTCTTGGCGTTCATCCACGAGCCCTTGAGGATGTTCACCTACGGAATCGCCTTGACCGCCCTCTCCGTGGCCTTCG
GCTACTTGTGGGTCGAGCTGGCGGGGCTGGACCCGAAGACCCAAGCTAGGAACTTGATAGAGTCCGGCCTCCACGTCCCC
GGGGCGAGGAGCGACCCGAGGCACTTGGAAAAGATACTGGCCAAGTACATATACCCGTTGACCATACTGTCCAGCATAAT
CGTGGCCTTGTTAGTTATAGTGGCCGACATATTCGGGGCCTACGGAACCGGGACCGGGCTCTTGTTGGCGACGATGATCT
TACAGCAGTACTATACTATGTTGACGTACGAGAGGGCGATAGAGACATATCCCCTACTCAGAAAGGTCCTCGGAGAGTGA

Upstream 100 bases:

>100_bases
AGCCCGCCCCCTTTTCCGGGCTCGGGCACCCCGGCTCCGACCCCAAGGGACCGGAGCCCTTTTATTAATCAACCCCCACG
GCGAGGGCGGGGACGCTGAA

Downstream 100 bases:

>100_bases
AGGGCATGATGAGGGTAGTCATTGCCACCGGAGTTCCCGGCGTGGGCAAGACCACGGTCACCAGCAAGGCTGTGGAGATG
TTAAAGGAGAAGGGTTACAA

Product: protein translocase subunit secY/sec61 alpha

Products: NA

Alternate protein names: Protein transport protein SEC61 subunit alpha homolog [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MQDLGRKALEVLAEIGTYVPAVPRPKRKINLYKRLTWTALALVAYLMMSNIPLPGVSVQTSFNLLLMNIVFAANAGTLMQ
LGIGPIVTAGLVLQLLVGAKIIDLDLTDPEDKKLFTLAQKGFAVVLAVFEAIGLVLSGSLWTTVTPDGVVVYNPPPAPVI
VLDMLLLAGATILVIIMDEMIQKGYGLGSGISLFIAASVVSGIAWEFAGWFSQAGQLIWAGLVPAALKCGLASVILGNPL
GAPKVPGTQVVCDGRRVPVGAMPDLIGFLATVVMIAAIAYLSSVKIQVPLVVKEMRGMRIKIPLNLLYVTNIPVLLAAII
FANIQTVASHAPGSPLSAVAYYLTPPRGLLAFIHEPLRMFTYGIALTALSVAFGYLWVELAGLDPKTQARNLIESGLHVP
GARSDPRHLEKILAKYIYPLTILSSIIVALLVIVADIFGAYGTGTGLLLATMILQQYYTMLTYERAIETYPLLRKVLGE

Sequences:

>Translated_479_residues
MQDLGRKALEVLAEIGTYVPAVPRPKRKINLYKRLTWTALALVAYLMMSNIPLPGVSVQTSFNLLLMNIVFAANAGTLMQ
LGIGPIVTAGLVLQLLVGAKIIDLDLTDPEDKKLFTLAQKGFAVVLAVFEAIGLVLSGSLWTTVTPDGVVVYNPPPAPVI
VLDMLLLAGATILVIIMDEMIQKGYGLGSGISLFIAASVVSGIAWEFAGWFSQAGQLIWAGLVPAALKCGLASVILGNPL
GAPKVPGTQVVCDGRRVPVGAMPDLIGFLATVVMIAAIAYLSSVKIQVPLVVKEMRGMRIKIPLNLLYVTNIPVLLAAII
FANIQTVASHAPGSPLSAVAYYLTPPRGLLAFIHEPLRMFTYGIALTALSVAFGYLWVELAGLDPKTQARNLIESGLHVP
GARSDPRHLEKILAKYIYPLTILSSIIVALLVIVADIFGAYGTGTGLLLATMILQQYYTMLTYERAIETYPLLRKVLGE
>Mature_479_residues
MQDLGRKALEVLAEIGTYVPAVPRPKRKINLYKRLTWTALALVAYLMMSNIPLPGVSVQTSFNLLLMNIVFAANAGTLMQ
LGIGPIVTAGLVLQLLVGAKIIDLDLTDPEDKKLFTLAQKGFAVVLAVFEAIGLVLSGSLWTTVTPDGVVVYNPPPAPVI
VLDMLLLAGATILVIIMDEMIQKGYGLGSGISLFIAASVVSGIAWEFAGWFSQAGQLIWAGLVPAALKCGLASVILGNPL
GAPKVPGTQVVCDGRRVPVGAMPDLIGFLATVVMIAAIAYLSSVKIQVPLVVKEMRGMRIKIPLNLLYVTNIPVLLAAII
FANIQTVASHAPGSPLSAVAYYLTPPRGLLAFIHEPLRMFTYGIALTALSVAFGYLWVELAGLDPKTQARNLIESGLHVP
GARSDPRHLEKILAKYIYPLTILSSIIVALLVIVADIFGAYGTGTGLLLATMILQQYYTMLTYERAIETYPLLRKVLGE

Specific function: Involved in protein export. Interacts with secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Homo sapiens, GI14589847, Length=497, Percent_Identity=30.1810865191147, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI7019415, Length=494, Percent_Identity=29.3522267206478, Blast_Score=207, Evalue=1e-53,
Organism=Homo sapiens, GI217330618, Length=496, Percent_Identity=29.0322580645161, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI217330616, Length=435, Percent_Identity=29.6551724137931, Blast_Score=186, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17543770, Length=493, Percent_Identity=30.4259634888438, Blast_Score=218, Evalue=7e-57,
Organism=Saccharomyces cerevisiae, GI6323411, Length=486, Percent_Identity=26.5432098765432, Blast_Score=189, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6319760, Length=476, Percent_Identity=21.6386554621849, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI19920826, Length=497, Percent_Identity=29.7786720321932, Blast_Score=213, Evalue=3e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201
- InterPro:   IPR019561 [H]

Pfam domain/function: PF10559 Plug_translocon; PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 51207; Mature: 51207

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDLGRKALEVLAEIGTYVPAVPRPKRKINLYKRLTWTALALVAYLMMSNIPLPGVSVQT
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHH
SFNLLLMNIVFAANAGTLMQLGIGPIVTAGLVLQLLVGAKIIDLDLTDPEDKKLFTLAQK
HHHHHHHHHHHHCCCCCEEHHCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHH
GFAVVLAVFEAIGLVLSGSLWTTVTPDGVVVYNPPPAPVIVLDMLLLAGATILVIIMDEM
HHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHH
IQKGYGLGSGISLFIAASVVSGIAWEFAGWFSQAGQLIWAGLVPAALKCGLASVILGNPL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
GAPKVPGTQVVCDGRRVPVGAMPDLIGFLATVVMIAAIAYLSSVKIQVPLVVKEMRGMRI
CCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHCCCEE
KIPLNLLYVTNIPVLLAAIIFANIQTVASHAPGSPLSAVAYYLTPPRGLLAFIHEPLRMF
EEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEECCCHHHHHHHHHHHHHH
TYGIALTALSVAFGYLWVELAGLDPKTQARNLIESGLHVPGARSDPRHLEKILAKYIYPL
HHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
TILSSIIVALLVIVADIFGAYGTGTGLLLATMILQQYYTMLTYERAIETYPLLRKVLGE
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQDLGRKALEVLAEIGTYVPAVPRPKRKINLYKRLTWTALALVAYLMMSNIPLPGVSVQT
CCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHH
SFNLLLMNIVFAANAGTLMQLGIGPIVTAGLVLQLLVGAKIIDLDLTDPEDKKLFTLAQK
HHHHHHHHHHHHCCCCCEEHHCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHH
GFAVVLAVFEAIGLVLSGSLWTTVTPDGVVVYNPPPAPVIVLDMLLLAGATILVIIMDEM
HHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHH
IQKGYGLGSGISLFIAASVVSGIAWEFAGWFSQAGQLIWAGLVPAALKCGLASVILGNPL
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
GAPKVPGTQVVCDGRRVPVGAMPDLIGFLATVVMIAAIAYLSSVKIQVPLVVKEMRGMRI
CCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHCCCEE
KIPLNLLYVTNIPVLLAAIIFANIQTVASHAPGSPLSAVAYYLTPPRGLLAFIHEPLRMF
EEEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCHHHHEEEECCCHHHHHHHHHHHHHH
TYGIALTALSVAFGYLWVELAGLDPKTQARNLIESGLHVPGARSDPRHLEKILAKYIYPL
HHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
TILSSIIVALLVIVADIFGAYGTGTGLLLATMILQQYYTMLTYERAIETYPLLRKVLGE
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10382966 [H]