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The map label for this gene is eno [H]

Identifier: 156937797

GI number: 156937797

Start: 897141

End: 898385

Strand: Reverse

Name: eno [H]

Synonym: Igni_1007

Alternate gene names: 156937797

Gene position: 898385-897141 (Counterclockwise)

Preceding gene: 156937803

Following gene: 156937796

Centisome position: 69.24

GC content: 59.76

Gene sequence:

>1245_bases
GTGAGGGGGCGCTGGATACTGGACTCCCGGGGCAACCCCACGGTGGAGGTAGACGTCTACACGGAGGGCGGCTTCGGCAG
AGCGGCCGCCCCCGCCGGGGCTTCCAAGGGGAGCAAGGAGGCCCTCGAGCTGAGGGACGGCGGGAACGCGTTCATGGGAA
AGGGCGTGCTGAAGGCCGTAAGGAACGTAAACGAAGTAATAGGCCCTTCGCTCGTAGGCATGGACTCCTTGGACCAGAAA
GAGATAGACATGAAAATGATAGAGTTAGACGGGACGGAGAATAAGTCCAAGCTGGGCGCGAACGCTATAGTCGCCACGAG
TATGGCGGTGGCCAAGGCGGCGGCGGACAGCTTGTCGGTACCCCTATATTACCACTTGGGCGGCGCCTTGGCCCAAACCT
TGCCCACCCCGCTCCTCAACGTGATAAACGGCGGGGCCCACGCGGGCAACGAGCTAGCCATACAAGAGTTCATGATAGTT
CCTTGGGACTTCTCTTCGTTCTCTGAGGCCCTCCAAGCGGCTTCCGAGATCTACCACTACTTGAAGAGCTACTTGAAGGA
GAAGTACGGCAAGTCCGCAATTAATGTGGGCGACGAGGGGGGCTTCGCTCCCCCCATGAGGCAGACGCGCGAGGCGCTGG
ACGCCTTGGTTAATGCAATAAAGAAGGCCGGGTATGAGGGAAGGGTTGCCTTGGCCTTGGACGCCGCCGCCACACACTTT
TACGACCAAGAGAAGGGGGTGTACCGAATAGACGGGAAGGAGCTGGATAGGGAGGGGCTGTTGGAGCTCTACGAGGAGCT
GATAAGGGACTACCCGATCGTTAGCATAGAAGATCCCCTCCACGAGGAAGACTGGGAAGGGTTTAAGGAGGCCGTCAAGA
GGTTGAAGATAAGGGTTGTAGGCGACGACTTGCTAGTTACCAACCCCAAGCTAGTAAAAAAGGCCATAGAGGAAGGGGTC
GCGAACGCGGTGCTCGTGAAGGTGAACCAAGTGGGGACCGTAACGGAGGCCTACGAGGTGGTTGACATGGCGAAGAGGGC
CTCGTGGGCAGCGATAGTAAGCCACCGCTCCGGCGAGACCGAGGACACGTTCATCTCGCACTTCGCCGTGGGCTCCGGGG
CGCCGGCGATAAAGGCCGGAGCGCCGGCGAGGGGCGAGAGGACCGCCAAGTACAACGAGCTGCTGAGGATTGAAGAGGAA
CTCGGGAGGCCTAAGTTCGCCAGGGACGCCTACTTCCGAACTTGA

Upstream 100 bases:

>100_bases
TTCCAACGTCCCTCTCCGACGGGCCGAGAGGGTTGGAAGGTCTTTACTGCCTTCCCGGAGGGCCCCCGGTGGTGGGGCCA
CGAGCACGGTAATCCGCTTC

Downstream 100 bases:

>100_bases
GTTACGTCGACCCCTCTTGACTAATAAAGCTCTTTTTTACCCCAATAGGGCACGGGTGGGTCAAGTGGCCACTGAGGAGA
AGAGGCCGACGTCGGTGGCG

Product: enolase

Products: NA

Alternate protein names: 2-phospho-D-glycerate hydro-lyase; 2-phosphoglycerate dehydratase [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MRGRWILDSRGNPTVEVDVYTEGGFGRAAAPAGASKGSKEALELRDGGNAFMGKGVLKAVRNVNEVIGPSLVGMDSLDQK
EIDMKMIELDGTENKSKLGANAIVATSMAVAKAAADSLSVPLYYHLGGALAQTLPTPLLNVINGGAHAGNELAIQEFMIV
PWDFSSFSEALQAASEIYHYLKSYLKEKYGKSAINVGDEGGFAPPMRQTREALDALVNAIKKAGYEGRVALALDAAATHF
YDQEKGVYRIDGKELDREGLLELYEELIRDYPIVSIEDPLHEEDWEGFKEAVKRLKIRVVGDDLLVTNPKLVKKAIEEGV
ANAVLVKVNQVGTVTEAYEVVDMAKRASWAAIVSHRSGETEDTFISHFAVGSGAPAIKAGAPARGERTAKYNELLRIEEE
LGRPKFARDAYFRT

Sequences:

>Translated_414_residues
MRGRWILDSRGNPTVEVDVYTEGGFGRAAAPAGASKGSKEALELRDGGNAFMGKGVLKAVRNVNEVIGPSLVGMDSLDQK
EIDMKMIELDGTENKSKLGANAIVATSMAVAKAAADSLSVPLYYHLGGALAQTLPTPLLNVINGGAHAGNELAIQEFMIV
PWDFSSFSEALQAASEIYHYLKSYLKEKYGKSAINVGDEGGFAPPMRQTREALDALVNAIKKAGYEGRVALALDAAATHF
YDQEKGVYRIDGKELDREGLLELYEELIRDYPIVSIEDPLHEEDWEGFKEAVKRLKIRVVGDDLLVTNPKLVKKAIEEGV
ANAVLVKVNQVGTVTEAYEVVDMAKRASWAAIVSHRSGETEDTFISHFAVGSGAPAIKAGAPARGERTAKYNELLRIEEE
LGRPKFARDAYFRT
>Mature_414_residues
MRGRWILDSRGNPTVEVDVYTEGGFGRAAAPAGASKGSKEALELRDGGNAFMGKGVLKAVRNVNEVIGPSLVGMDSLDQK
EIDMKMIELDGTENKSKLGANAIVATSMAVAKAAADSLSVPLYYHLGGALAQTLPTPLLNVINGGAHAGNELAIQEFMIV
PWDFSSFSEALQAASEIYHYLKSYLKEKYGKSAINVGDEGGFAPPMRQTREALDALVNAIKKAGYEGRVALALDAAATHF
YDQEKGVYRIDGKELDREGLLELYEELIRDYPIVSIEDPLHEEDWEGFKEAVKRLKIRVVGDDLLVTNPKLVKKAIEEGV
ANAVLVKVNQVGTVTEAYEVVDMAKRASWAAIVSHRSGETEDTFISHFAVGSGAPAIKAGAPARGERTAKYNELLRIEEE
LGRPKFARDAYFRT

Specific function: Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis [H]

COG id: COG0148

COG function: function code G; Enolase

Gene ontology:

Cell location: Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the archaeal cel

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enolase family [H]

Homologues:

Organism=Homo sapiens, GI301897477, Length=412, Percent_Identity=53.3980582524272, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI301897469, Length=412, Percent_Identity=53.3980582524272, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI4503571, Length=421, Percent_Identity=52.4940617577197, Blast_Score=424, Evalue=1e-119,
Organism=Homo sapiens, GI5803011, Length=412, Percent_Identity=52.4271844660194, Blast_Score=424, Evalue=1e-119,
Organism=Homo sapiens, GI301897479, Length=410, Percent_Identity=47.5609756097561, Blast_Score=358, Evalue=4e-99,
Organism=Homo sapiens, GI169201331, Length=340, Percent_Identity=26.1764705882353, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI169201757, Length=340, Percent_Identity=26.1764705882353, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI239744207, Length=340, Percent_Identity=26.1764705882353, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI1789141, Length=411, Percent_Identity=52.7980535279805, Blast_Score=386, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI71995829, Length=416, Percent_Identity=52.6442307692308, Blast_Score=421, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17536383, Length=416, Percent_Identity=52.6442307692308, Blast_Score=421, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI32563855, Length=184, Percent_Identity=46.7391304347826, Blast_Score=176, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6321693, Length=416, Percent_Identity=52.4038461538462, Blast_Score=398, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6323985, Length=419, Percent_Identity=49.8806682577566, Blast_Score=391, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6324974, Length=419, Percent_Identity=49.6420047732697, Blast_Score=389, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6324969, Length=419, Percent_Identity=49.6420047732697, Blast_Score=389, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6321968, Length=416, Percent_Identity=51.6826923076923, Blast_Score=366, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24580918, Length=426, Percent_Identity=52.112676056338, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24580916, Length=426, Percent_Identity=52.112676056338, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24580920, Length=426, Percent_Identity=52.112676056338, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24580914, Length=426, Percent_Identity=52.112676056338, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI281360527, Length=426, Percent_Identity=52.112676056338, Blast_Score=412, Evalue=1e-115,
Organism=Drosophila melanogaster, GI17137654, Length=426, Percent_Identity=52.112676056338, Blast_Score=412, Evalue=1e-115,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000941
- InterPro:   IPR020810
- InterPro:   IPR020809
- InterPro:   IPR020811 [H]

Pfam domain/function: PF00113 Enolase_C; PF03952 Enolase_N [H]

EC number: =4.2.1.11 [H]

Molecular weight: Translated: 44933; Mature: 44933

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00164 ENOLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGRWILDSRGNPTVEVDVYTEGGFGRAAAPAGASKGSKEALELRDGGNAFMGKGVLKAV
CCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHEEECCCCCHHHHHHHHHHH
RNVNEVIGPSLVGMDSLDQKEIDMKMIELDGTENKSKLGANAIVATSMAVAKAAADSLSV
HHHHHHHCCCCCCCCCCCCHHHCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHCCC
PLYYHLGGALAQTLPTPLLNVINGGAHAGNELAIQEFMIVPWDFSSFSEALQAASEIYHY
CHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHH
LKSYLKEKYGKSAINVGDEGGFAPPMRQTREALDALVNAIKKAGYEGRVALALDAAATHF
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHH
YDQEKGVYRIDGKELDREGLLELYEELIRDYPIVSIEDPLHEEDWEGFKEAVKRLKIRVV
HHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHEEEEEE
GDDLLVTNPKLVKKAIEEGVANAVLVKVNQVGTVTEAYEVVDMAKRASWAAIVSHRSGET
CCCEEECCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
EDTFISHFAVGSGAPAIKAGAPARGERTAKYNELLRIEEELGRPKFARDAYFRT
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCC
>Mature Secondary Structure
MRGRWILDSRGNPTVEVDVYTEGGFGRAAAPAGASKGSKEALELRDGGNAFMGKGVLKAV
CCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHEEECCCCCHHHHHHHHHHH
RNVNEVIGPSLVGMDSLDQKEIDMKMIELDGTENKSKLGANAIVATSMAVAKAAADSLSV
HHHHHHHCCCCCCCCCCCCHHHCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHCCC
PLYYHLGGALAQTLPTPLLNVINGGAHAGNELAIQEFMIVPWDFSSFSEALQAASEIYHY
CHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHH
LKSYLKEKYGKSAINVGDEGGFAPPMRQTREALDALVNAIKKAGYEGRVALALDAAATHF
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHH
YDQEKGVYRIDGKELDREGLLELYEELIRDYPIVSIEDPLHEEDWEGFKEAVKRLKIRVV
HHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHEEEEEE
GDDLLVTNPKLVKKAIEEGVANAVLVKVNQVGTVTEAYEVVDMAKRASWAAIVSHRSGET
CCCEEECCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
EDTFISHFAVGSGAPAIKAGAPARGERTAKYNELLRIEEELGRPKFARDAYFRT
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA