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The map label for this gene is ribH [H]

Identifier: 156937727

GI number: 156937727

Start: 829183

End: 829602

Strand: Reverse

Name: ribH [H]

Synonym: Igni_0936

Alternate gene names: 156937727

Gene position: 829602-829183 (Counterclockwise)

Preceding gene: 156937728

Following gene: 156937724

Centisome position: 63.94

GC content: 62.14

Gene sequence:

>420_bases
GTGAGGCTCGGCATAGTGGTGTCTGAGTTCAACTACGATATAACCAGACTTATGCTAGAGAAGGCTCTGGACCACGCTAA
GTTCCTCGGGGTGGAGGAGGTCTTGGTGCTCAAGGTGCCGGGCTCTTTCGAGGCCCCGCTGGCCGCGAAGAGGCTGCTGG
AGGAGGGCTGCGACGCGGTAGCTGTCTTGGGCGCCGTGATAAAGGGCGAGACCGACCACGACCAAGTGGTGGCCCACCAG
GTCGCTAGGAAGTTAATGGACTTGTCTTTGGAGTACGGGAAGCCCGTCACCTTAGGCGTTATAGGCCCCGGGGCCACGCG
GGAGCAAGCGGCCGAGAGGATAGAGGAGTACGCGCGCCGCGCCGTGGAGGCTGCAGTCAAGGCTTGGAAGCGGTTGAACG
AGGGGCCTCAGCTGGCGTGA

Upstream 100 bases:

>100_bases
CAAGGTCAAGTACTTGGTAGTGCCGACCTCCCTGGGCCTCGTGGTAGCCGCTAAAACTTGATACGCTCCTCTCCAGAGCC
GGACGGAAGGTGTTGAGGGC

Downstream 100 bases:

>100_bases
GTAGTGAGGTGCGCTATCAAGGACTGGACGTCGAAGAAGAACGACCCCTCGTCGGCGGCCTTCCTCCCCTTCTTTTTCAC
GGTCTCAGTCAAGCATATGG

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MRLGIVVSEFNYDITRLMLEKALDHAKFLGVEEVLVLKVPGSFEAPLAAKRLLEEGCDAVAVLGAVIKGETDHDQVVAHQ
VARKLMDLSLEYGKPVTLGVIGPGATREQAAERIEEYARRAVEAAVKAWKRLNEGPQLA

Sequences:

>Translated_139_residues
MRLGIVVSEFNYDITRLMLEKALDHAKFLGVEEVLVLKVPGSFEAPLAAKRLLEEGCDAVAVLGAVIKGETDHDQVVAHQ
VARKLMDLSLEYGKPVTLGVIGPGATREQAAERIEEYARRAVEAAVKAWKRLNEGPQLA
>Mature_139_residues
MRLGIVVSEFNYDITRLMLEKALDHAKFLGVEEVLVLKVPGSFEAPLAAKRLLEEGCDAVAVLGAVIKGETDHDQVVAHQ
VARKLMDLSLEYGKPVTLGVIGPGATREQAAERIEEYARRAVEAAVKAWKRLNEGPQLA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=137, Percent_Identity=37.2262773722628, Blast_Score=67, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324429, Length=147, Percent_Identity=30.6122448979592, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 15176; Mature: 15176

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGIVVSEFNYDITRLMLEKALDHAKFLGVEEVLVLKVPGSFEAPLAAKRLLEEGCDAV
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCHHHHHHHHHCCHHH
AVLGAVIKGETDHDQVVAHQVARKLMDLSLEYGKPVTLGVIGPGATREQAAERIEEYARR
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
AVEAAVKAWKRLNEGPQLA
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRLGIVVSEFNYDITRLMLEKALDHAKFLGVEEVLVLKVPGSFEAPLAAKRLLEEGCDAV
CCCEEEEECCCHHHHHHHHHHHHHHHHHCCHHHEEEEECCCCCCCCHHHHHHHHHCCHHH
AVLGAVIKGETDHDQVVAHQVARKLMDLSLEYGKPVTLGVIGPGATREQAAERIEEYARR
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
AVEAAVKAWKRLNEGPQLA
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA