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The map label for this gene is trxB [H]

Identifier: 156937702

GI number: 156937702

Start: 808908

End: 809894

Strand: Direct

Name: trxB [H]

Synonym: Igni_0911

Alternate gene names: 156937702

Gene position: 808908-809894 (Clockwise)

Preceding gene: 156937701

Following gene: 156937707

Centisome position: 62.34

GC content: 60.18

Gene sequence:

>987_bases
GTGCTGAGGCTCGGAGCGCCGGCCAAGAGGCCGAAGGGAGGGGAGTTCGACGTCGTAGTGATAGGCGCGGGTCCCGGAGG
GCTGACTGCCGCTATGTACGCTGCCAGGTTGGGGTTGAAGACGGTAGTCTTGGAGAAGGACAACAAGCCGGGGGGTAGGA
CCTCCCTAGCCCCCGTGGTCGAGGACTACCCCGGCATAGACAAGATAGGCGGCGAGGAGCTGGCCCAACGCTTCTTGAAC
CAAGCCACCAAGTTCGGGGCTCAAGTGGTGTTCGGGGAAAGGGTCGTGGACGCCGACTTCTCCAAGGAGGAGATGAAGGT
GGTGAGGACCCACAAGGGGAGGGAATACAAGGCCCCCGCGGTGATCATAGCGACCGGCGTCTCCACTAAAGGCTTGGGCG
TCAAGGGCGAGAAGGAGTACTTCGGCAAGGGCGTGAGCTACTGCGTAGTGTGCGACGCCCCCTTCTTCAAGGGCGAACCC
ATGGCCTTGGTGGGTTACGACGACCACGCGATGGAGGAGGCGGTCTACATGACCTCCCTCGCCAGCAAGGTATACATAGT
AACTCACGGGAAGAAGATCGAAGCCTCCGAGTCTTACATGAGCGTGTTAAGGAACAACCCGAAGGTCGAAATACTTGAAG
GAGCTAAGGTGAAGGAGATAGTGGGCGACGGCCAGAAGGTGACCGGGCTGGTGGTGGAGCTGCCGGACGGCACTACCAAG
ACCTTGCCGGTGAGGGCCGTGTTCATATCTTACGGCGAGGTCCCCAGCACCGAGATATTCAAGAAGGCTGGGGTGGAGGT
GGACGAAAGGGGCTTCATAAAGATAGACCCCTACACTAGGACCAACGTGCCCGGAGTCTTCGCGGTGGGCGACGTGACCG
GGATAGGCTTCCAGATAGTGATCGCCGCCGGCCACGGGGCCACCGCCGCCTTAGAGGCCTCGAAGTACGTGAAGAGGATC
AAGAGGAAGGTAGCGGTCAAACAATAG

Upstream 100 bases:

>100_bases
ATTAAAGAGATAGCCGAGGAGCTCAAGAACTTGCTTTTCGGTTAGTCAGGTCGTTAATTAAAATTTCGCCCTCCCCACGG
AGCGAAAGCGGTGTGAAAGC

Downstream 100 bases:

>100_bases
CCTCTTTTAAGCGCGGGAAGAAGTAGACATTATAAGGCGTGTAGTTGGCGCTCAAGTTGGCCTGTTCGGCGGCCATCTCG
AATATCCTCTTGTGTTTCCT

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MLRLGAPAKRPKGGEFDVVVIGAGPGGLTAAMYAARLGLKTVVLEKDNKPGGRTSLAPVVEDYPGIDKIGGEELAQRFLN
QATKFGAQVVFGERVVDADFSKEEMKVVRTHKGREYKAPAVIIATGVSTKGLGVKGEKEYFGKGVSYCVVCDAPFFKGEP
MALVGYDDHAMEEAVYMTSLASKVYIVTHGKKIEASESYMSVLRNNPKVEILEGAKVKEIVGDGQKVTGLVVELPDGTTK
TLPVRAVFISYGEVPSTEIFKKAGVEVDERGFIKIDPYTRTNVPGVFAVGDVTGIGFQIVIAAGHGATAALEASKYVKRI
KRKVAVKQ

Sequences:

>Translated_328_residues
MLRLGAPAKRPKGGEFDVVVIGAGPGGLTAAMYAARLGLKTVVLEKDNKPGGRTSLAPVVEDYPGIDKIGGEELAQRFLN
QATKFGAQVVFGERVVDADFSKEEMKVVRTHKGREYKAPAVIIATGVSTKGLGVKGEKEYFGKGVSYCVVCDAPFFKGEP
MALVGYDDHAMEEAVYMTSLASKVYIVTHGKKIEASESYMSVLRNNPKVEILEGAKVKEIVGDGQKVTGLVVELPDGTTK
TLPVRAVFISYGEVPSTEIFKKAGVEVDERGFIKIDPYTRTNVPGVFAVGDVTGIGFQIVIAAGHGATAALEASKYVKRI
KRKVAVKQ
>Mature_328_residues
MLRLGAPAKRPKGGEFDVVVIGAGPGGLTAAMYAARLGLKTVVLEKDNKPGGRTSLAPVVEDYPGIDKIGGEELAQRFLN
QATKFGAQVVFGERVVDADFSKEEMKVVRTHKGREYKAPAVIIATGVSTKGLGVKGEKEYFGKGVSYCVVCDAPFFKGEP
MALVGYDDHAMEEAVYMTSLASKVYIVTHGKKIEASESYMSVLRNNPKVEILEGAKVKEIVGDGQKVTGLVVELPDGTTK
TLPVRAVFISYGEVPSTEIFKKAGVEVDERGFIKIDPYTRTNVPGVFAVGDVTGIGFQIVIAAGHGATAALEASKYVKRI
KRKVAVKQ

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI50301238, Length=337, Percent_Identity=26.7062314540059, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI226437568, Length=298, Percent_Identity=26.8456375838926, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI21389617, Length=298, Percent_Identity=26.8456375838926, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI65787454, Length=298, Percent_Identity=26.8456375838926, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787114, Length=314, Percent_Identity=33.1210191082803, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=32.6923076923077, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=316, Percent_Identity=35.126582278481, Blast_Score=173, Evalue=4e-44,
Organism=Saccharomyces cerevisiae, GI6321898, Length=312, Percent_Identity=33.974358974359, Blast_Score=162, Evalue=9e-41,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 35074; Mature: 35074

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRLGAPAKRPKGGEFDVVVIGAGPGGLTAAMYAARLGLKTVVLEKDNKPGGRTSLAPVV
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHH
EDYPGIDKIGGEELAQRFLNQATKFGAQVVFGERVVDADFSKEEMKVVRTHKGREYKAPA
HCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCEEECCCCCHHHHHHHHHCCCCCCCCCE
VIIATGVSTKGLGVKGEKEYFGKGVSYCVVCDAPFFKGEPMALVGYDDHAMEEAVYMTSL
EEEEECCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHH
ASKVYIVTHGKKIEASESYMSVLRNNPKVEILEGAKVKEIVGDGQKVTGLVVELPDGTTK
CCEEEEEECCCEECCHHHHHHHHHCCCCEEEECCCCHHHHHCCCCEEEEEEEECCCCCCC
TLPVRAVFISYGEVPSTEIFKKAGVEVDERGFIKIDPYTRTNVPGVFAVGDVTGIGFQIV
CEEEEEEEEECCCCCCHHHHHHCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCEEEE
IAAGHGATAALEASKYVKRIKRKVAVKQ
EEECCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLRLGAPAKRPKGGEFDVVVIGAGPGGLTAAMYAARLGLKTVVLEKDNKPGGRTSLAPVV
CCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHH
EDYPGIDKIGGEELAQRFLNQATKFGAQVVFGERVVDADFSKEEMKVVRTHKGREYKAPA
HCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCEEECCCCCHHHHHHHHHCCCCCCCCCE
VIIATGVSTKGLGVKGEKEYFGKGVSYCVVCDAPFFKGEPMALVGYDDHAMEEAVYMTSL
EEEEECCCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHH
ASKVYIVTHGKKIEASESYMSVLRNNPKVEILEGAKVKEIVGDGQKVTGLVVELPDGTTK
CCEEEEEECCCEECCHHHHHHHHHCCCCEEEECCCCHHHHHCCCCEEEEEEEECCCCCCC
TLPVRAVFISYGEVPSTEIFKKAGVEVDERGFIKIDPYTRTNVPGVFAVGDVTGIGFQIV
CEEEEEEEEECCCCCCHHHHHHCCCCCCCCCCEEECCCCCCCCCEEEEECCCCCCCEEEE
IAAGHGATAALEASKYVKRIKRKVAVKQ
EEECCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]