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The map label for this gene is hypA

Identifier: 156937618

GI number: 156937618

Start: 735487

End: 735906

Strand: Direct

Name: hypA

Synonym: Igni_0825

Alternate gene names: 156937618

Gene position: 735487-735906 (Clockwise)

Preceding gene: 156937611

Following gene: 156937619

Centisome position: 56.68

GC content: 52.14

Gene sequence:

>420_bases
TTGCACGAGGCAAGCTACGCCCTCACGATAGTGGATACCGTCATGGAGGCCCTTAAAAAGGAGGGCCTCGAGAACGTGAA
AGTAACCAAAGTCATAATTAAGATAGGAGAGTTGAGCTTGGTGGACCCCGTAGCTTTGCGTAACGCCTTCGAGGCCTACT
CCCTAGGCAGCCCCTTGGAGGGGGCCGAGCTGGAGATAGAGGTGGTGCCGTCCAAGTTCGTGTGTAAGAGGTGTGGCCAC
GAGTGGACCTTTAAAGACGTCTACCCAGAGCTCAAGGCTAACATACCGGTCATCCACTTGTATCCCCACTTAGTGAAGGA
CCTACTCAAGTGTCCCAAGTGCAACAGTTCCGAGGTGGAAATTGTGCAAGGGACGGAGTTCGTAATAGAGGGATTCGAAT
ATCAAGAGAGTAACGAGTGA

Upstream 100 bases:

>100_bases
AGGACGCTGCGGGCCCCGCCGGAGACGGCCAAGCTCTCGTTGTACGTATTGCTAAAGTATTTCAACGTCTCGACGCCCTC
CAGAGCAACGGAGCCGCGGG

Downstream 100 bases:

>100_bases
ACCCTAGAGTCAACCAACGCGTTTTTATTATTAATTAACGTTCGCGCACTGGCTTTTGGAGGCACGAGATGTCCGCCCTG
AGCGCGCGGAAAGCGCAGAG

Product: hydrogenase expression/synthesis, HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MHEASYALTIVDTVMEALKKEGLENVKVTKVIIKIGELSLVDPVALRNAFEAYSLGSPLEGAELEIEVVPSKFVCKRCGH
EWTFKDVYPELKANIPVIHLYPHLVKDLLKCPKCNSSEVEIVQGTEFVIEGFEYQESNE

Sequences:

>Translated_139_residues
MHEASYALTIVDTVMEALKKEGLENVKVTKVIIKIGELSLVDPVALRNAFEAYSLGSPLEGAELEIEVVPSKFVCKRCGH
EWTFKDVYPELKANIPVIHLYPHLVKDLLKCPKCNSSEVEIVQGTEFVIEGFEYQESNE
>Mature_139_residues
MHEASYALTIVDTVMEALKKEGLENVKVTKVIIKIGELSLVDPVALRNAFEAYSLGSPLEGAELEIEVVPSKFVCKRCGH
EWTFKDVYPELKANIPVIHLYPHLVKDLLKCPKCNSSEVEIVQGTEFVIEGFEYQESNE

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_IGNH4 (A8AAQ5)

Other databases:

- EMBL:   CP000816
- RefSeq:   YP_001435414.1
- STRING:   A8AAQ5
- GeneID:   5562494
- GenomeReviews:   CP000816_GR
- KEGG:   iho:Igni_0825
- eggNOG:   arNOG08691
- HOGENOM:   HBG688671
- OMA:   HEWALAD
- BioCyc:   IHOS453591:IGNI_0825-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 15609; Mature: 15609

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEASYALTIVDTVMEALKKEGLENVKVTKVIIKIGELSLVDPVALRNAFEAYSLGSPLE
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC
GAELEIEVVPSKFVCKRCGHEWTFKDVYPELKANIPVIHLYPHLVKDLLKCPKCNSSEVE
CCEEEEEECCHHHHHHHCCCCCCHHHHCHHHHCCCCEEEECHHHHHHHHHCCCCCCCCEE
IVQGTEFVIEGFEYQESNE
EEECCCEEHCCCCCCCCCC
>Mature Secondary Structure
MHEASYALTIVDTVMEALKKEGLENVKVTKVIIKIGELSLVDPVALRNAFEAYSLGSPLE
CCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCC
GAELEIEVVPSKFVCKRCGHEWTFKDVYPELKANIPVIHLYPHLVKDLLKCPKCNSSEVE
CCEEEEEECCHHHHHHHCCCCCCHHHHCHHHHCCCCEEEECHHHHHHHHHCCCCCCCCEE
IVQGTEFVIEGFEYQESNE
EEECCCEEHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA