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The map label for this gene is 156937171

Identifier: 156937171

GI number: 156937171

Start: 332295

End: 333356

Strand: Direct

Name: 156937171

Synonym: Igni_0377

Alternate gene names: NA

Gene position: 332295-333356 (Clockwise)

Preceding gene: 156937170

Following gene: 156937172

Centisome position: 25.61

GC content: 61.77

Gene sequence:

>1062_bases
TTGTACGTCTGCTCGGCCAACGTGGTGAAGGTCGATAGGCACTACGACAAGAGCTCTTCTGCCTTGGCCGTGGAGGCCCT
CGCGCCGGTGGTGGAGGCGTGCGGCGAGCCCGACGCGCTGGTAGTTAGCACTTACTTGTCCCGCTACCAAGAGTCCTTCG
GCAACTTGGGAGCGCTCTTGGCCGAGTACTTGGGCTTCAAGGGGGAGGTGTACGAGGTCTCCGCCGGGGAGGCCTCGGGG
GGCGCGGCGGTGGCTCTCGCATACAAGCTCGTTAGGTCGGGCCTCAAGAGGGTACTGGTAGTGGGGGTGGACAAGACTAA
CGACTTCCAGTCAAAGAAGGCCGTGAAACACTTACAAACCCTCTTAAGTCCTTACGAGTCCTTCTACGGCCTGACCTACG
CCGGCGCCCACGCGCTCGCTGCCTCCTTGTACATGAAGGAGTTCAACGTCAGTAGGGAGGAGCTCGCCCACTGGGCGGTG
GTCATGCACGACAACGCCACCGCCGTGCCCCACGCACAGCTGAGGTTCCCGGTGACGGTCGAGAAGGTCTTGAACTCCAA
CTCCGTAGCGGAGCCCTTGAAGCTCTTGGACTCTCACCCGTTCAGCGACGGGGCCGCGGCGGTCATGCTTACTTCCGAGA
CCTCGCCAGTAGCCTTGGAAGTCGCGGCAGCTTCGTCCAAACTGACTTTGGCAGAGAGGGACTTAACTTTCATGGAAAGC
GCCAAGGCGGCGATGGAGGCCTTGGGGAACCCGGAGCCGGAGGCGGTGGAGGTCCACGACCCCTTCAGCGTGGCCGGCGT
CATAGCGCTCGAGTCCTTAGGCCTCGCCCCTAGGGGGAAGGGCATTAAGTACTTGTTAGAGAACGCCCACTCGGTCAACC
CCTCTGGGGGGTTGAAGGCGAGGGGTCACCCGGTGGGGGCCACGGGGGTTTACCAAGTGGCCGAGGGCTTCCTCGCGATA
ACCTCCGGCCTGGGCAAGCTGGGCAAGGTCAGCAGTTTCTTGGCCCACAGTTCCAACTTGATGGGGGCTACTACGTACTT
AACGTACATGAGGGAGGTGTAA

Upstream 100 bases:

>100_bases
CGCCCACCACGCAGAGCTACATAGAGAGGAGGAAGGTTATAGACTACGCGACCTACTTGCGGTTCAGGAACAAGATAAAG
AAGTTGGCGAGGTGAGGCCG

Downstream 100 bases:

>100_bases
GCCGTGGAGATAAGTCCGGCTGCTGTTTGGAGGGAGAAGCCCTATAGGTATAGGCTAGAGGTGAGGAGGTGCCCCAGCTG
CAAGAGGGTGTTCAGAGAGG

Product: acetyl-CoA acetyltransferase

Products: CoA; 3-oxoacyl-CoA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MYVCSANVVKVDRHYDKSSSALAVEALAPVVEACGEPDALVVSTYLSRYQESFGNLGALLAEYLGFKGEVYEVSAGEASG
GAAVALAYKLVRSGLKRVLVVGVDKTNDFQSKKAVKHLQTLLSPYESFYGLTYAGAHALAASLYMKEFNVSREELAHWAV
VMHDNATAVPHAQLRFPVTVEKVLNSNSVAEPLKLLDSHPFSDGAAAVMLTSETSPVALEVAAASSKLTLAERDLTFMES
AKAAMEALGNPEPEAVEVHDPFSVAGVIALESLGLAPRGKGIKYLLENAHSVNPSGGLKARGHPVGATGVYQVAEGFLAI
TSGLGKLGKVSSFLAHSSNLMGATTYLTYMREV

Sequences:

>Translated_353_residues
MYVCSANVVKVDRHYDKSSSALAVEALAPVVEACGEPDALVVSTYLSRYQESFGNLGALLAEYLGFKGEVYEVSAGEASG
GAAVALAYKLVRSGLKRVLVVGVDKTNDFQSKKAVKHLQTLLSPYESFYGLTYAGAHALAASLYMKEFNVSREELAHWAV
VMHDNATAVPHAQLRFPVTVEKVLNSNSVAEPLKLLDSHPFSDGAAAVMLTSETSPVALEVAAASSKLTLAERDLTFMES
AKAAMEALGNPEPEAVEVHDPFSVAGVIALESLGLAPRGKGIKYLLENAHSVNPSGGLKARGHPVGATGVYQVAEGFLAI
TSGLGKLGKVSSFLAHSSNLMGATTYLTYMREV
>Mature_353_residues
MYVCSANVVKVDRHYDKSSSALAVEALAPVVEACGEPDALVVSTYLSRYQESFGNLGALLAEYLGFKGEVYEVSAGEASG
GAAVALAYKLVRSGLKRVLVVGVDKTNDFQSKKAVKHLQTLLSPYESFYGLTYAGAHALAASLYMKEFNVSREELAHWAV
VMHDNATAVPHAQLRFPVTVEKVLNSNSVAEPLKLLDSHPFSDGAAAVMLTSETSPVALEVAAASSKLTLAERDLTFMES
AKAAMEALGNPEPEAVEVHDPFSVAGVIALESLGLAPRGKGIKYLLENAHSVNPSGGLKARGHPVGATGVYQVAEGFLAI
TSGLGKLGKVSSFLAHSSNLMGATTYLTYMREV

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI302344760, Length=295, Percent_Identity=26.7796610169492, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI19923233, Length=295, Percent_Identity=26.7796610169492, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI302344767, Length=288, Percent_Identity=26.3888888888889, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI302344762, Length=233, Percent_Identity=27.4678111587983, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI55956775, Length=227, Percent_Identity=26.8722466960352, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17537653, Length=300, Percent_Identity=27, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19921506, Length=282, Percent_Identity=30.1418439716312, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24585051, Length=282, Percent_Identity=29.4326241134752, Blast_Score=91, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020617
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: 2.3.1.16

Molecular weight: Translated: 37296; Mature: 37296

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVCSANVVKVDRHYDKSSSALAVEALAPVVEACGEPDALVVSTYLSRYQESFGNLGALL
CEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AEYLGFKGEVYEVSAGEASGGAAVALAYKLVRSGLKRVLVVGVDKTNDFQSKKAVKHLQT
HHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHH
LLSPYESFYGLTYAGAHALAASLYMKEFNVSREELAHWAVVMHDNATAVPHAQLRFPVTV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEECCCCCCCCCCEECCCHH
EKVLNSNSVAEPLKLLDSHPFSDGAAAVMLTSETSPVALEVAAASSKLTLAERDLTFMES
HHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEHHHHHHHHHH
AKAAMEALGNPEPEAVEVHDPFSVAGVIALESLGLAPRGKGIKYLLENAHSVNPSGGLKA
HHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCC
RGHPVGATGVYQVAEGFLAITSGLGKLGKVSSFLAHSSNLMGATTYLTYMREV
CCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MYVCSANVVKVDRHYDKSSSALAVEALAPVVEACGEPDALVVSTYLSRYQESFGNLGALL
CEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AEYLGFKGEVYEVSAGEASGGAAVALAYKLVRSGLKRVLVVGVDKTNDFQSKKAVKHLQT
HHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHH
LLSPYESFYGLTYAGAHALAASLYMKEFNVSREELAHWAVVMHDNATAVPHAQLRFPVTV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHEEEEEECCCCCCCCCCEECCCHH
EKVLNSNSVAEPLKLLDSHPFSDGAAAVMLTSETSPVALEVAAASSKLTLAERDLTFMES
HHHHCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEECCCCEEEHHHHHHHHHH
AKAAMEALGNPEPEAVEVHDPFSVAGVIALESLGLAPRGKGIKYLLENAHSVNPSGGLKA
HHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCCC
RGHPVGATGVYQVAEGFLAITSGLGKLGKVSSFLAHSSNLMGATTYLTYMREV
CCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acetyl-CoA

Specific reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]