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The map label for this gene is 156936906

Identifier: 156936906

GI number: 156936906

Start: 102732

End: 103712

Strand: Reverse

Name: 156936906

Synonym: Igni_0111

Alternate gene names: NA

Gene position: 103712-102732 (Counterclockwise)

Preceding gene: 156936907

Following gene: 156936905

Centisome position: 7.99

GC content: 58.82

Gene sequence:

>981_bases
ATGAAGGTCGTCTGGAGCGAGAGCTTCACGAAACACTTCTTCGCGCCCCCTTCAATAGTTCGCGAGTGGACTGCCAGGAT
GAAGAAGTTCAAAGAGGTCGTAAGCGGTAAGGTAGAGCTAGTCCCCCCGGAGGAGGCCTCCTTAGAACTCTTCGAGCTGG
TGCACTGTAGGAGCTTAATAGAGAGGATAATGGAGTTAGACTCCATCGGAGGCGTCATAGACTACGGGGACACCTACATC
TACCCTGGCTCCGCCTCGACGCTCGTGGACGTCTTGGGAGGGGTGTTGAGGGCGGCTGAGCTCGCGGAGGAGCAAGGGTT
CGGCTACACCCCATACGGAGGCTTACACCACGCCGGCAAGTGCAGGGCGGCCGGCTTCTGTCCGGCCAACGACGTAGCGG
TCTTGGCGGAGGCCTTGGCTAGGAAGGGCTATCGGGTAGCCTACTTGGACTTCGACGTTCACCACGGGGACGGCACCCAA
GAGATATTCTACGAAAGGTCAGACGTCCTCACCGTGAGCGTACACATGTACTACCCCGGCTTCTACCCCGGGACGGGCTG
GTACGCGGAGCTCGGCGCCGGCGAAGGCAAGGGCTATTCCCTCAACGTGCCCCTTCCCCCGAGGTCCGGTGACGAGGCGT
ACGCAATGGTAATAGACCTAATTGTGAAGAGGGCCATTGAGAACTTCGAGCCGGACTTCGTGGTCGCCCAAATGGGCGTC
GACGGCTACTGGAAGGACCCCTTGGGCGGAGCCCTGAACCTAACCGCTAACACCTATTACAAGATAGGGGAATTTCTGAG
AAGTATAGAGGTCCCCGTAGCGGGCGCTGGAGGAGGGGGTTACGGGGAAGGGGCAGTGGTTCCGATGCTGAGCGAGCTGG
GGTTTAGGATAGAGGAGGAGCCTACGCCCTCCCCGCCCGAAGCGTTAGAAAGGGTAGAGGAGGTCCTCCGTTACTTCGAA
GAAAACGTTAGTTGGTTCTAA

Upstream 100 bases:

>100_bases
ATATACACCGGCCCGTGGCAGCTCAAGTACAGAGATACCGTGAAGCTCTACTGCGAAGTCATGGGGAGGGCCACTTCTTA
CATCAAGTGAGGGGAGCGCT

Downstream 100 bases:

>100_bases
AGCCCGCGGGTCGAGAAGCCCCTAGGGTGTGACGTCGTGGAGACCGTAGACTTTAACACCTTTAGTAAGGTAGACTTAAG
GGTCGGCAAGGTGATAGAGG

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKVVWSESFTKHFFAPPSIVREWTARMKKFKEVVSGKVELVPPEEASLELFELVHCRSLIERIMELDSIGGVIDYGDTYI
YPGSASTLVDVLGGVLRAAELAEEQGFGYTPYGGLHHAGKCRAAGFCPANDVAVLAEALARKGYRVAYLDFDVHHGDGTQ
EIFYERSDVLTVSVHMYYPGFYPGTGWYAELGAGEGKGYSLNVPLPPRSGDEAYAMVIDLIVKRAIENFEPDFVVAQMGV
DGYWKDPLGGALNLTANTYYKIGEFLRSIEVPVAGAGGGGYGEGAVVPMLSELGFRIEEEPTPSPPEALERVEEVLRYFE
ENVSWF

Sequences:

>Translated_326_residues
MKVVWSESFTKHFFAPPSIVREWTARMKKFKEVVSGKVELVPPEEASLELFELVHCRSLIERIMELDSIGGVIDYGDTYI
YPGSASTLVDVLGGVLRAAELAEEQGFGYTPYGGLHHAGKCRAAGFCPANDVAVLAEALARKGYRVAYLDFDVHHGDGTQ
EIFYERSDVLTVSVHMYYPGFYPGTGWYAELGAGEGKGYSLNVPLPPRSGDEAYAMVIDLIVKRAIENFEPDFVVAQMGV
DGYWKDPLGGALNLTANTYYKIGEFLRSIEVPVAGAGGGGYGEGAVVPMLSELGFRIEEEPTPSPPEALERVEEVLRYFE
ENVSWF
>Mature_326_residues
MKVVWSESFTKHFFAPPSIVREWTARMKKFKEVVSGKVELVPPEEASLELFELVHCRSLIERIMELDSIGGVIDYGDTYI
YPGSASTLVDVLGGVLRAAELAEEQGFGYTPYGGLHHAGKCRAAGFCPANDVAVLAEALARKGYRVAYLDFDVHHGDGTQ
EIFYERSDVLTVSVHMYYPGFYPGTGWYAELGAGEGKGYSLNVPLPPRSGDEAYAMVIDLIVKRAIENFEPDFVVAQMGV
DGYWKDPLGGALNLTANTYYKIGEFLRSIEVPVAGAGGGGYGEGAVVPMLSELGFRIEEEPTPSPPEALERVEEVLRYFE
ENVSWF

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128860, Length=190, Percent_Identity=41.0526315789474, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI8923769, Length=256, Percent_Identity=32.421875, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI13128862, Length=169, Percent_Identity=40.8284023668639, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI262073088, Length=205, Percent_Identity=34.1463414634146, Blast_Score=125, Evalue=4e-29,
Organism=Homo sapiens, GI293336691, Length=178, Percent_Identity=38.7640449438202, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI262073092, Length=193, Percent_Identity=33.6787564766839, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI17158039, Length=144, Percent_Identity=39.5833333333333, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI30795202, Length=144, Percent_Identity=39.5833333333333, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI30795204, Length=144, Percent_Identity=39.5833333333333, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI148539870, Length=144, Percent_Identity=38.8888888888889, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI169234807, Length=144, Percent_Identity=38.8888888888889, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI153085395, Length=174, Percent_Identity=36.2068965517241, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI13128864, Length=177, Percent_Identity=35.5932203389831, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI62750347, Length=144, Percent_Identity=39.5833333333333, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI62750349, Length=144, Percent_Identity=39.5833333333333, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI217272877, Length=255, Percent_Identity=26.2745098039216, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI209862883, Length=249, Percent_Identity=26.1044176706827, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI20070354, Length=161, Percent_Identity=31.6770186335404, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17561978, Length=191, Percent_Identity=43.455497382199, Blast_Score=140, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17508561, Length=256, Percent_Identity=35.546875, Blast_Score=138, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17534739, Length=193, Percent_Identity=36.7875647668394, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17540334, Length=224, Percent_Identity=33.4821428571429, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI193206283, Length=224, Percent_Identity=33.4821428571429, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17540332, Length=224, Percent_Identity=33.4821428571429, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193209491, Length=250, Percent_Identity=32.4, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17537347, Length=278, Percent_Identity=25.5395683453237, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6321244, Length=169, Percent_Identity=41.4201183431953, Blast_Score=135, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6323999, Length=169, Percent_Identity=42.0118343195266, Blast_Score=129, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6325325, Length=186, Percent_Identity=35.4838709677419, Blast_Score=106, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6324307, Length=220, Percent_Identity=34.0909090909091, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24657891, Length=169, Percent_Identity=43.7869822485207, Blast_Score=138, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24644244, Length=169, Percent_Identity=41.4201183431953, Blast_Score=129, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24642146, Length=295, Percent_Identity=29.1525423728814, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24642144, Length=295, Percent_Identity=29.1525423728814, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24642142, Length=295, Percent_Identity=29.1525423728814, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281360899, Length=289, Percent_Identity=29.0657439446367, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI281360799, Length=239, Percent_Identity=32.2175732217573, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281360801, Length=239, Percent_Identity=32.2175732217573, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24641720, Length=239, Percent_Identity=32.2175732217573, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 35878; Mature: 35878

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVWSESFTKHFFAPPSIVREWTARMKKFKEVVSGKVELVPPEEASLELFELVHCRSLI
CEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHH
ERIMELDSIGGVIDYGDTYIYPGSASTLVDVLGGVLRAAELAEEQGFGYTPYGGLHHAGK
HHHHHHHHCCCEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
CRAAGFCPANDVAVLAEALARKGYRVAYLDFDVHHGDGTQEIFYERSDVLTVSVHMYYPG
CCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHCCCCCEEEEEEEEEECC
FYPGTGWYAELGAGEGKGYSLNVPLPPRSGDEAYAMVIDLIVKRAIENFEPDFVVAQMGV
CCCCCCCEEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCC
DGYWKDPLGGALNLTANTYYKIGEFLRSIEVPVAGAGGGGYGEGAVVPMLSELGFRIEEE
CCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHCCCEECCC
PTPSPPEALERVEEVLRYFEENVSWF
CCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKVVWSESFTKHFFAPPSIVREWTARMKKFKEVVSGKVELVPPEEASLELFELVHCRSLI
CEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHH
ERIMELDSIGGVIDYGDTYIYPGSASTLVDVLGGVLRAAELAEEQGFGYTPYGGLHHAGK
HHHHHHHHCCCEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
CRAAGFCPANDVAVLAEALARKGYRVAYLDFDVHHGDGTQEIFYERSDVLTVSVHMYYPG
CCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHCCCCCEEEEEEEEEECC
FYPGTGWYAELGAGEGKGYSLNVPLPPRSGDEAYAMVIDLIVKRAIENFEPDFVVAQMGV
CCCCCCCEEECCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCC
DGYWKDPLGGALNLTANTYYKIGEFLRSIEVPVAGAGGGGYGEGAVVPMLSELGFRIEEE
CCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHCCCEECCC
PTPSPPEALERVEEVLRYFEENVSWF
CCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]